메뉴 건너뛰기




Volumn 21, Issue 12, 2007, Pages 2485-2494

Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ARSENIC TRIOXIDE; BCR ABL PROTEIN; ETOPOSIDE; HYBRID PROTEIN; IMATINIB; ISOPROTEIN; LIPOCORTIN 5; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRYPAN BLUE; WT1 PROTEIN;

EID: 36348970549     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404924     Document Type: Article
Times cited : (27)

References (55)
  • 1
    • 0035835816 scopus 로고    scopus 로고
    • Wilms tumour and the WT1 gene
    • Lee SB, Haber DA. Wilms tumour and the WT1 gene. Exp Cell Res 2001; 264: 74-99.
    • (2001) Exp Cell Res , vol.264 , pp. 74-99
    • Lee, S.B.1    Haber, D.A.2
  • 2
    • 0035827923 scopus 로고    scopus 로고
    • WT1 proteins: Functions in growth and differentiation
    • Scharnhorst V, van der Eb AJ, Jochemsen AG. WT1 proteins: Functions in growth and differentiation. Gene 2001; 273: 141-161.
    • (2001) Gene , vol.273 , pp. 141-161
    • Scharnhorst, V.1    van der Eb, A.J.2    Jochemsen, A.G.3
  • 3
    • 0025099787 scopus 로고
    • Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
    • Call KM, Glaser T, Ito CY, Buckler AJ, Pelletier J, Haber DA et al. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 1990; 60: 509-520.
    • (1990) Cell , vol.60 , pp. 509-520
    • Call, K.M.1    Glaser, T.2    Ito, C.Y.3    Buckler, A.J.4    Pelletier, J.5    Haber, D.A.6
  • 4
    • 0025098654 scopus 로고
    • Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
    • Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns GAP. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature 1990; 343: 774-778.
    • (1990) Nature , vol.343 , pp. 774-778
    • Gessler, M.1    Poustka, A.2    Cavenee, W.3    Neve, R.L.4    Orkin, S.H.5    Bruns, G.A.P.6
  • 5
    • 0028850524 scopus 로고
    • Expression of the tumor suppressor gene WT1 in both human and mouse bone marrow
    • Fraizer GC, Patmasiriwat P, Zhang X, Saunders GF. Expression of the tumor suppressor gene WT1 in both human and mouse bone marrow. Blood 1995; 86: 4704-4706.
    • (1995) Blood , vol.86 , pp. 4704-4706
    • Fraizer, G.C.1    Patmasiriwat, P.2    Zhang, X.3    Saunders, G.F.4
  • 6
    • 0031010990 scopus 로고    scopus 로고
    • Expression of the Wilms'tumor gene (WT1) in normal hemopoiesis
    • Baird PN, Simmons PJ. Expression of the Wilms'tumor gene (WT1) in normal hemopoiesis. Exp Hematol 1997; 25: 312-320.
    • (1997) Exp Hematol , vol.25 , pp. 312-320
    • Baird, P.N.1    Simmons, P.J.2
  • 7
    • 0030812823 scopus 로고    scopus 로고
    • The Wilms' tumor gene is expressed in a subset of CD34+ progenitdrs and downregulated early in the course of differentiation in vitro
    • Maurer U, Brieger J, Weidmann E, Mitrou PS, Hoelzer D, Bergmann L. The Wilms' tumor gene is expressed in a subset of CD34+ progenitdrs and downregulated early in the course of differentiation in vitro. Exp Hematol 1997; 25: 945-950.
    • (1997) Exp Hematol , vol.25 , pp. 945-950
    • Maurer, U.1    Brieger, J.2    Weidmann, E.3    Mitrou, P.S.4    Hoelzer, D.5    Bergmann, L.6
  • 8
    • 0031135108 scopus 로고    scopus 로고
    • Wilms' tumor gene expression in human CD34+ hematopoietic progenitors during fetal development and early clonogenic growth
    • Menssen HD, Renkl HJ, Entezami M, Thiel E. Wilms' tumor gene expression in human CD34+ hematopoietic progenitors during fetal development and early clonogenic growth. Blood 1997; 89: 3486-3487.
    • (1997) Blood , vol.89 , pp. 3486-3487
    • Menssen, H.D.1    Renkl, H.J.2    Entezami, M.3    Thiel, E.4
  • 9
    • 0036179060 scopus 로고    scopus 로고
    • Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells
    • Hosen N, Sonoda Y, Oji Y, Kimura T, Minamiguchi H, Tamaki H et al. Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells. Br J Haematol 2002; 116: 409-420.
    • (2002) Br J Haematol , vol.116 , pp. 409-420
    • Hosen, N.1    Sonoda, Y.2    Oji, Y.3    Kimura, T.4    Minamiguchi, H.5    Tamaki, H.6
  • 10
    • 34447634119 scopus 로고    scopus 로고
    • The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis
    • Hosen N, Shirakata T, Nishida S, Yanagihara M, Tsuboi A, Kawakami M et al. The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis. Leukemia 2007; 21: 1783-1791.
    • (2007) Leukemia , vol.21 , pp. 1783-1791
    • Hosen, N.1    Shirakata, T.2    Nishida, S.3    Yanagihara, M.4    Tsuboi, A.5    Kawakami, M.6
  • 13
    • 0026751042 scopus 로고
    • Expression of the Wilms' tumor gene (WT1) inhuman leukemias
    • Miwa H, Beran M, Saunders GF. Expression of the Wilms' tumor gene (WT1) inhuman leukemias. Leukemia 1992; 6: 405-409.
    • (1992) Leukemia , vol.6 , pp. 405-409
    • Miwa, H.1    Beran, M.2    Saunders, G.F.3
  • 15
    • 0028130136 scopus 로고
    • WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia
    • Inoue K, Sugiyama H, Ogawa H, Nakagawa M, Yamagami T, Miwa H et al. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 1994; 84: 3071-3079.
    • (1994) Blood , vol.84 , pp. 3071-3079
    • Inoue, K.1    Sugiyama, H.2    Ogawa, H.3    Nakagawa, M.4    Yamagami, T.5    Miwa, H.6
  • 16
    • 0029069227 scopus 로고
    • Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias
    • Menssen HD, Renkl HJ, kodeck U, Maurer J, Notter M, Schwartz S et al. Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias. Leukemia 1995; 9: 1060-1067.
    • (1995) Leukemia , vol.9 , pp. 1060-1067
    • Menssen, H.D.1    Renkl, H.J.2    kodeck, U.3    Maurer, J.4    Notter, M.5    Schwartz, S.6
  • 17
    • 0029860337 scopus 로고    scopus 로고
    • Increased expression of the Wilms tumor gene (WT1) at relapse in acute leukemia
    • Tamaki H, Ogawa H, Inoue K, Soma T, Yamagami T, Miyake S et al Increased expression of the Wilms tumor gene (WT1) at relapse in acute leukemia. Blood 1996; 88: 4396-4398.
    • (1996) Blood , vol.88 , pp. 4396-4398
    • Tamaki, H.1    Ogawa, H.2    Inoue, K.3    Soma, T.4    Yamagami, T.5    Miyake, S.6
  • 18
    • 0027931178 scopus 로고
    • Wilms' tumor gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells
    • Phelan SA, Lindberg C, Call KM. Wilms' tumor gene, WT1, mRNA is down-regulated during induction of erythroid and megakaryocytic differentiation of K562 cells. Cell Growth Differ 1994; 5: 677-686.
    • (1994) Cell Growth Differ , vol.5 , pp. 677-686
    • Phelan, S.A.1    Lindberg, C.2    Call, K.M.3
  • 19
    • 0028294563 scopus 로고
    • Downregulation of Wilms' tumor gene (wt1) during myelomonocytic differentiation in HL60 cells
    • Sekiya M, Adachi M, Hinoda Y, Imai K, Yachi A. Downregulation of Wilms' tumor gene (wt1) during myelomonocytic differentiation in HL60 cells. Blood 1994; 83: 1876-1882.
    • (1994) Blood , vol.83 , pp. 1876-1882
    • Sekiya, M.1    Adachi, M.2    Hinoda, Y.3    Imai, K.4    Yachi, A.5
  • 20
    • 0032522925 scopus 로고    scopus 로고
    • Wilms' tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells
    • Inoue K, Tamaki H, Ogawa H, Oka Y, Soma T, Tatekawa T et al. Wilms' tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells. Blood 1998; 91: 2969-2976.
    • (1998) Blood , vol.91 , pp. 2969-2976
    • Inoue, K.1    Tamaki, H.2    Ogawa, H.3    Oka, Y.4    Soma, T.5    Tatekawa, T.6
  • 21
    • 0032545941 scopus 로고    scopus 로고
    • Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program
    • Svedberg H, Chylicki K, Baldetorp B, Rauscher III FJ, Gullberg U. Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program. Oncogene 1998; 16: 925-932.
    • (1998) Oncogene , vol.16 , pp. 925-932
    • Svedberg, H.1    Chylicki, K.2    Baldetorp, B.3    Rauscher III, F.J.4    Gullberg, U.5
  • 22
    • 0032944068 scopus 로고    scopus 로고
    • Constitutive expression of the Wilms' tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF)
    • Tsuboi A, Oka Y, Ogawa H, Elisseeva OA, Tamaki H, Oji Y et al. Constitutive expression of the Wilms' tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF). Leuk Res 1999; 23: 499-505.
    • (1999) Leuk Res , vol.23 , pp. 499-505
    • Tsuboi, A.1    Oka, Y.2    Ogawa, H.3    Elisseeva, O.A.4    Tamaki, H.5    Oji, Y.6
  • 23
    • 33645729159 scopus 로고    scopus 로고
    • AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1
    • Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S et al. AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. Blood 2006; 107: 3303-3312.
    • (2006) Blood , vol.107 , pp. 3303-3312
    • Nishida, S.1    Hosen, N.2    Shirakata, T.3    Kanato, K.4    Yanagihara, M.5    Nakatsuka, S.6
  • 24
    • 4143119022 scopus 로고    scopus 로고
    • Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation
    • Cilloni D, Messa F, Gottardi E, Fava M, Arruga F, Defilippi I et al. Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation. Cancer 2004; 101: 979-988.
    • (2004) Cancer , vol.101 , pp. 979-988
    • Cilloni, D.1    Messa, F.2    Gottardi, E.3    Fava, M.4    Arruga, F.5    Defilippi, I.6
  • 25
    • 14644425319 scopus 로고    scopus 로고
    • Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
    • Ren R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 2005; 5: 172-183.
    • (2005) Nat Rev Cancer , vol.5 , pp. 172-183
    • Ren, R.1
  • 26
    • 22144435106 scopus 로고    scopus 로고
    • DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis
    • Svensson E, Eriksson H, Gekas C, Olofsson T, Richter J, Gullberg U. DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis. Exp Cell Res 2005; 308: 211-221.
    • (2005) Exp Cell Res , vol.308 , pp. 211-221
    • Svensson, E.1    Eriksson, H.2    Gekas, C.3    Olofsson, T.4    Richter, J.5    Gullberg, U.6
  • 27
    • 0034663147 scopus 로고    scopus 로고
    • Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein
    • Kelly PF, Vandergriff J, Nathwani A, Nienhuis AW, Vanin EF. Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. Blood 2000; 96: 1206-1214.
    • (2000) Blood , vol.96 , pp. 1206-1214
    • Kelly, P.F.1    Vandergriff, J.2    Nathwani, A.3    Nienhuis, A.W.4    Vanin, E.F.5
  • 28
    • 8844265285 scopus 로고    scopus 로고
    • Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of cytokine-stimulated CD34+ human marrow cells in vitro
    • Edvardsson L, Dykes J, Olsson ML, Olofsson T. Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of cytokine-stimulated CD34+ human marrow cells in vitro. Br J Haematol 2004; 127: 451-463.
    • (2004) Br J Haematol , vol.127 , pp. 451-463
    • Edvardsson, L.1    Dykes, J.2    Olsson, M.L.3    Olofsson, T.4
  • 29
    • 0036278859 scopus 로고    scopus 로고
    • Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream
    • Ginzinger DG. Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream. Exp Hematol 2002; 30 503-512.
    • (2002) Exp Hematol , vol.30 , pp. 503-512
    • Ginzinger, D.G.1
  • 30
    • 1542503883 scopus 로고    scopus 로고
    • Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a)
    • Hakansson P, Lassen C, Olofsson T, Baldetorp B, Karlsson A, Gullberg U et al. Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a). Leukemia 2004; 18: 538-547.
    • (2004) Leukemia , vol.18 , pp. 538-547
    • Hakansson, P.1    Lassen, C.2    Olofsson, T.3    Baldetorp, B.4    Karlsson, A.5    Gullberg, U.6
  • 31
    • 0030710557 scopus 로고    scopus 로고
    • Transactivation of an intronic hematopoietic-specific enhancer of the human Wilms' tumor 1 gene by GATA-1 and c-Myb
    • Zhang X, Xing G, Fraizer GC, Saunders GF. Transactivation of an intronic hematopoietic-specific enhancer of the human Wilms' tumor 1 gene by GATA-1 and c-Myb. J Biol Chem 1997; 272: 29272-29280.
    • (1997) J Biol Chem , vol.272 , pp. 29272-29280
    • Zhang, X.1    Xing, G.2    Fraizer, G.C.3    Saunders, G.F.4
  • 32
    • 0028903992 scopus 로고
    • GATA-1 transactivates the WT1 hematopoietic specific enhancer
    • Wu Y, Fraizer GC, Saunders GF. GATA-1 transactivates the WT1 hematopoietic specific enhancer. J Biol Chem 1995; 270: 5944-5949.
    • (1995) J Biol Chem , vol.270 , pp. 5944-5949
    • Wu, Y.1    Fraizer, G.C.2    Saunders, G.F.3
  • 33
    • 0036565871 scopus 로고    scopus 로고
    • Modulation of p210(BCR-ABL) activity in transduced primary human hematopoietic cells controls lineage programming
    • Chalandon Y, Jiang X, Hazlewood G, Loutet S, Conneally E, Eaves A et al. Modulation of p210(BCR-ABL) activity in transduced primary human hematopoietic cells controls lineage programming. Blood 2002; 99: 3197-3204.
    • (2002) Blood , vol.99 , pp. 3197-3204
    • Chalandon, Y.1    Jiang, X.2    Hazlewood, G.3    Loutet, S.4    Conneally, E.5    Eaves, A.6
  • 34
    • 0035871781 scopus 로고    scopus 로고
    • A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector
    • Zhao RC, Jiang Y, Verfaillie CM. A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector. Blood 2001; 97: 2406-2412.
    • (2001) Blood , vol.97 , pp. 2406-2412
    • Zhao, R.C.1    Jiang, Y.2    Verfaillie, C.M.3
  • 35
    • 0029880547 scopus 로고    scopus 로고
    • A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines
    • Algar EM, Khromykh T, Smith SI, Blackburn DM, Bryson GJ, Smith PJ. A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines. Oncogene 1996; 12: 1005-1014.
    • (1996) Oncogene , vol.12 , pp. 1005-1014
    • Algar, E.M.1    Khromykh, T.2    Smith, S.I.3    Blackburn, D.M.4    Bryson, G.J.5    Smith, P.J.6
  • 36
    • 9244237089 scopus 로고    scopus 로고
    • Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis
    • Yamagami T, Sugiyama H, Inoue K, Ogawa H, Tatekawa T, Hirata M et al. Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis. Blood 1996; 87: 2878-2884.
    • (1996) Blood , vol.87 , pp. 2878-2884
    • Yamagami, T.1    Sugiyama, H.2    Inoue, K.3    Ogawa, H.4    Tatekawa, T.5    Hirata, M.6
  • 37
    • 33745165056 scopus 로고    scopus 로고
    • Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway
    • Ito K, Oji Y, Tatsumi N, Shimizu S, Kanai Y, Nakazawa T et al. Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway. Oncogene 2006; 25: 4217-4229.
    • (2006) Oncogene , vol.25 , pp. 4217-4229
    • Ito, K.1    Oji, Y.2    Tatsumi, N.3    Shimizu, S.4    Kanai, Y.5    Nakazawa, T.6
  • 39
    • 33748555528 scopus 로고    scopus 로고
    • Down-regulation of wt1 expression in leukemia cell lines as part of apoptotic effect in arsenic treatment using two compounds
    • Glienke W, Chow KU, Bauer N, Bergmann L. Down-regulation of wt1 expression in leukemia cell lines as part of apoptotic effect in arsenic treatment using two compounds. Leuk Lymphoma 2006; 47: 1629-1638.
    • (2006) Leuk Lymphoma , vol.47 , pp. 1629-1638
    • Glienke, W.1    Chow, K.U.2    Bauer, N.3    Bergmann, L.4
  • 40
    • 0034110424 scopus 로고    scopus 로고
    • Differential responses of Bcl-2 family genes to etoposide in chronic myeloid leukemia K562 cells
    • Fukumi S, Horiguchi-Yamada J, Nakada S, Nagai M, Ohno T, Yamada H. Differential responses of Bcl-2 family genes to etoposide in chronic myeloid leukemia K562 cells. Mol Cell Biochem 2000; 206: 43-50.
    • (2000) Mol Cell Biochem , vol.206 , pp. 43-50
    • Fukumi, S.1    Horiguchi-Yamada, J.2    Nakada, S.3    Nagai, M.4    Ohno, T.5    Yamada, H.6
  • 41
    • 33947615372 scopus 로고    scopus 로고
    • Alterations in mRNA expression of apoptosis-related genes BCL2, BAX, FAS, caspase-3, and the novel member BCL2L12 after treatment of human leukemic cell line HL60 with the antineoplastic agent etoposide
    • Floros KV, Thomadaki H, Florou D, Talieri M, Scorilas A. Alterations in mRNA expression of apoptosis-related genes BCL2, BAX, FAS, caspase-3, and the novel member BCL2L12 after treatment of human leukemic cell line HL60 with the antineoplastic agent etoposide. Ann NY Acad Sci 2006; 1090: 89-97.
    • (2006) Ann NY Acad Sci , vol.1090 , pp. 89-97
    • Floros, K.V.1    Thomadaki, H.2    Florou, D.3    Talieri, M.4    Scorilas, A.5
  • 42
    • 15044346433 scopus 로고    scopus 로고
    • BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice
    • Chalandon Y, Jiang X, Christ O, Loutet S, Thanopoulou E, Eaves A et al. BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice. Leukemia 2005; 19: 442-448.
    • (2005) Leukemia , vol.19 , pp. 442-448
    • Chalandon, Y.1    Jiang, X.2    Christ, O.3    Loutet, S.4    Thanopoulou, E.5    Eaves, A.6
  • 43
    • 0029063970 scopus 로고
    • Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells
    • Skorski T, Kanakaraj P, Nieborowska-Skorska M, Ratajczak MZ, Wen SC, Zon G et al. Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells. Blood 1995; 86: 726-736.
    • (1995) Blood , vol.86 , pp. 726-736
    • Skorski, T.1    Kanakaraj, P.2    Nieborowska-Skorska, M.3    Ratajczak, M.Z.4    Wen, S.C.5    Zon, G.6
  • 44
    • 29744445248 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway and cancer
    • Stokoe D. The phosphoinositide 3-kinase pathway and cancer. Expert Rev Mol Med 2005; 7: 1-22.
    • (2005) Expert Rev Mol Med , vol.7 , pp. 1-22
    • Stokoe, D.1
  • 45
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature 2001; 411: 355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 46
    • 14944373628 scopus 로고    scopus 로고
    • HER2/neu increases the expression of Wilms Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells
    • Tuna M, Chavez-Reyes A, Tari AM. HER2/neu increases the expression of Wilms Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells. Oncogene 2005; 24: 1648-1652.
    • (2005) Oncogene , vol.24 , pp. 1648-1652
    • Tuna, M.1    Chavez-Reyes, A.2    Tari, A.M.3
  • 48
    • 0028206250 scopus 로고
    • Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter
    • Fraizer GC, Wu YJ, Hewitt SM, Maity T, Ton CC, Huff V. Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. J Biol Chem 1994; 269: 8892-8900.
    • (1994) J Biol Chem , vol.269 , pp. 8892-8900
    • Fraizer, G.C.1    Wu, Y.J.2    Hewitt, S.M.3    Maity, T.4    Ton, C.C.5    Huff, V.6
  • 49
    • 4143151967 scopus 로고    scopus 로고
    • Genomic mechanisms of p210BCR-ABL signaling: Induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis
    • Ray S, Lu Y, Kaufmann SH, Gustafson WC, Karp JE, Boldogh I et al. Genomic mechanisms of p210BCR-ABL signaling: Induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis. J Biol Chem 2004; 279: 35604-35615.
    • (2004) J Biol Chem , vol.279 , pp. 35604-35615
    • Ray, S.1    Lu, Y.2    Kaufmann, S.H.3    Gustafson, W.C.4    Karp, J.E.5    Boldogh, I.6
  • 50
    • 31544481433 scopus 로고    scopus 로고
    • Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/ AKT signaling pathway
    • Zhao W, Kitidis C, Fleming MD, Lodish HF, Ghaffari S. Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/ AKT signaling pathway. Blood 2006; 107: 907-915.
    • (2006) Blood , vol.107 , pp. 907-915
    • Zhao, W.1    Kitidis, C.2    Fleming, M.D.3    Lodish, H.F.4    Ghaffari, S.5
  • 51
    • 33744472466 scopus 로고    scopus 로고
    • The Wilms' tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene
    • Dame C, Kirschner KM, Bartz KV, Wallach T, Hussels CS, Scholz H. The Wilms' tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene. Blood 2006; 107: 4282-4290.
    • (2006) Blood , vol.107 , pp. 4282-4290
    • Dame, C.1    Kirschner, K.M.2    Bartz, K.V.3    Wallach, T.4    Hussels, C.S.5    Scholz, H.6
  • 52
    • 12344262623 scopus 로고    scopus 로고
    • RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML
    • Na IK, Kreuzer KA, Lupberger J, Dorken B, le Coutre P. RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML. Leuk Res 2005; 29: 343-345.
    • (2005) Leuk Res , vol.29 , pp. 343-345
    • Na, I.K.1    Kreuzer, K.A.2    Lupberger, J.3    Dorken, B.4    le Coutre, P.5
  • 53
    • 0033565656 scopus 로고    scopus 로고
    • WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene
    • Mayo MW, Wang CY, Drouin SS, Madrid LV, Marshall AF, Reed JC et al. WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene. EMBO J 1999; 18: 3990-4003.
    • (1999) EMBO J , vol.18 , pp. 3990-4003
    • Mayo, M.W.1    Wang, C.Y.2    Drouin, S.S.3    Madrid, L.V.4    Marshall, A.F.5    Reed, J.C.6
  • 54
    • 0033741271 scopus 로고    scopus 로고
    • Overexpression of murine WT1 +/+ and -/- isoforms has no effect on chemoresistance but delays differentiation in the K562 leukemia cell line
    • Carrington D, Algar E. Overexpression of murine WT1 +/+ and -/- isoforms has no effect on chemoresistance but delays differentiation in the K562 leukemia cell line. Leuk Res 2000; 24: 927-936.
    • (2000) Leuk Res , vol.24 , pp. 927-936
    • Carrington, D.1    Algar, E.2
  • 55
    • 33749510073 scopus 로고    scopus 로고
    • Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic
    • Kuroda J, Puthalakath H, Cragg MS, Kelly PN, Bouillet P, Huang DC et al. Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. Proc Natl Acad Sci USA 2006; 103: 14907-14912.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14907-14912
    • Kuroda, J.1    Puthalakath, H.2    Cragg, M.S.3    Kelly, P.N.4    Bouillet, P.5    Huang, D.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.