Overexpression of murine WT1 +/+ and -/- isoforms has no effect on chemoresistance but delays differentiation in the K562 leukemia cell line

Leukemia Research

Volumn 24, Issue 11, 2000, Pages 927-936

  Carrington, D ^a   Algar, E ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Chemoresistance; Differentiation; Leukemia; Oncog ene; Proliferation; Wilms' tumor gene

Indexed keywords

CISPLATIN; DOXORUBICIN; GENE PRODUCT; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN WT1; REAGENT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL DIFFERENTIATION; CELL STRAIN K 562; CONTROLLED STUDY; ERYTHROLEUKEMIA CELL; GENE OVEREXPRESSION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MEGAKARYOPOIESIS; MOUSE; NEPHROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CISPLATIN; DNA-BINDING PROTEINS; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; GENES, WILMS TUMOR; HEMATOPOIESIS; HUMANS; K562 CELLS; MEGAKARYOCYTES; MICE; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTORS; TRANSFECTION; WT1 PROTEINS;

EID: 0033741271     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(00)00064-3     Document Type: Article

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