Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells

Journal of Neuro-Oncology

Volumn 85, Issue 3, 2007, Pages 245-254

  Carapancea, Mia ^a   Cosaceanu, Daria ^a   Budiu, Raluca ^a   Kwiecinska, Anna ^a   Tataranu, Ligia ^b   Ciubotaru, Vasile ^b   Alexandru, Oana ^a   Banita, Monica ^c   Pisoschi, Catalina ^c   Bäcklund, Magnus L ^a   Lewensohn, Rolf ^a   Dricu, Anica ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Clinic Hospital Bagdasar Arseni Bucharest   (Romania)

^c UNIVERSITY OF MEDICINE AND PHARMACY OF CRAIOVA   (Romania)

Author keywords

High grade glioma; IGF 1R; Ionizingradiation; JNK1; PDGFR

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SOMATOMEDIN C RECEPTOR;

ARTICLE; CANCER CELL CULTURE; CANCER GRADING; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GAMMA IRRADIATION; GLIOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; IONIZING RADIATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; COMBINED MODALITY THERAPY; DRUG COMBINATIONS; GLIOMA; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 8; RADIATION DOSAGE; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; RECEPTOR, IGF TYPE 1; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; TYRPHOSTINS;

EID: 36348968816     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-007-9417-0     Document Type: Article

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