The specific monocarboxylate transporter-1 (MCT-1) inhibitor, AR-C117977, induces donor-specific suppression, reducing acute and chronic allograft rejection in the rat

Transplantation

Volumn 84, Issue 9, 2007, Pages 1191-1199

  Ekberg, Henrik ^a   Qi, Zhongquan ^a,c   Pahlman, Clara ^a   Veress, Béla ^a   Bundick, Robert V ^b   Craggs, Robert I ^b   Holness, Elain ^b   Edwards, Susan ^b   Murray, Clare M ^b   Ferguson, Douglas ^b   Kerry, Philip J ^b   Wilson, Elaine ^b   Donald, David K ^b  

^a LUND UNIVERSITY   (Sweden)

^b ASTRAZENECA   (United Kingdom)

^c XIAMEN UNIVERSITY   (China)

Author keywords

Alloimmune responses; Donor specific suppression; Immunosuppression; Monocarboxylate transporter

Indexed keywords

AR C117977; AR C122982; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; MONOCARBOXYLATE TRANSPORTER 1 INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHIOLITIS OBLITERANS; CARDIAC GRAFT REJECTION; CONTROLLED STUDY; DRUG BLOOD LEVEL; GRAFT REJECTION; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; HISTOLOGY; IMMUNE RESPONSE; MALE; MIXED LYMPHOCYTE REACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL TIME; VASCULAR DISEASE;

ACUTE DISEASE; ANIMALS; ATHEROSCLEROSIS; CHRONIC DISEASE; GRAFT REJECTION; GRAFT SURVIVAL; GRAFT VS HOST REACTION; HEART TRANSPLANTATION; HETEROCYCLIC COMPOUNDS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE CULTURE TEST, MIXED; MONOCARBOXYLIC ACID TRANSPORTERS; POSTOPERATIVE COMPLICATIONS; RATS; RATS, INBRED LEW; SYMPORTERS; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC;

EID: 36249023288     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000287541.53389.be     Document Type: Article

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