메뉴 건너뛰기




Volumn 15, Issue 6, 2007, Pages 881-888

New strategy for the antifibrotic therapy with oral administration of FR260330 (a selective inducible nitric oxide synthase inhibitor) in rat experimental liver cirrhosis

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ANTIFIBROTIC AGENT; FR 260330; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE; THIOACETAMIDE; UNCLASSIFIED DRUG;

EID: 36249006445     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2007.00308.x     Document Type: Article
Times cited : (14)

References (40)
  • 2
    • 0033854016 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine- treated rats
    • Nakamura T, Sakata R, Ueno T, Sata M, Ueno H. Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats. Hepatology 2000 32 : 247 55.
    • (2000) Hepatology , vol.32 , pp. 247-55
    • Nakamura, T.1    Sakata, R.2    Ueno, T.3    Sata, M.4    Ueno, H.5
  • 3
    • 0028941524 scopus 로고
    • Interferon alpha and gamma inhibit proliferation and collagen synthesis of human Ito cells in culture
    • Mallat A, Preaux AM, Blazejewski S, Rosenbaum J, Dhumeaux D, Mavier P. Interferon alpha and gamma inhibit proliferation and collagen synthesis of human Ito cells in culture. Hepatology 1995 21 : 1003 10.
    • (1995) Hepatology , vol.21 , pp. 1003-10
    • Mallat, A.1    Preaux, A.M.2    Blazejewski, S.3    Rosenbaum, J.4    Dhumeaux, D.5    Mavier, P.6
  • 4
    • 0036107548 scopus 로고    scopus 로고
    • Transcriptional regulation of hepatic stellate cell activation
    • Mann DA, Smart DE. Transcriptional regulation of hepatic stellate cell activation. Gut 2002 50 : 891 6.
    • (2002) Gut , vol.50 , pp. 891-6
    • Mann, D.A.1    Smart, D.E.2
  • 6
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis - Mechanisms and treatment strategies
    • Friedman SL. The cellular basis of hepatic fibrosis - mechanisms and treatment strategies. N Engl J Med 1993 328 : 1828 35.
    • (1993) N Engl J Med , vol.328 , pp. 1828-35
    • Friedman, S.L.1
  • 7
    • 0028109801 scopus 로고
    • Transforming growth factor beta in tissue fibrosis
    • Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med 1994 331 : 1286 92.
    • (1994) N Engl J Med , vol.331 , pp. 1286-92
    • Border, W.A.1    Noble, N.A.2
  • 8
    • 0034809804 scopus 로고    scopus 로고
    • Hepatic stellate cells as a target for the treatment of liver fibrosis
    • Bataller R, Brenner DA. Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin Liver Dis 2001 21 : 437 51.
    • (2001) Semin Liver Dis , vol.21 , pp. 437-51
    • Bataller, R.1    Brenner, D.A.2
  • 10
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991 43 : 109 42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-42
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 11
    • 0032910873 scopus 로고    scopus 로고
    • Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: Implications in inflammation
    • Grisham MB, Jourd'Heuil D, Wink DA. Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation. Am J Physiol 1999 276 : G315 21.
    • (1999) Am J Physiol , vol.276
    • Grisham, M.B.1    Jourd'Heuil, D.2    Wink, D.A.3
  • 12
    • 0034146023 scopus 로고    scopus 로고
    • Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion
    • Liu P, Xu B, Spokas E, Lai PS, Wong PY. Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion. Shock 2000 13 : 217 23.
    • (2000) Shock , vol.13 , pp. 217-23
    • Liu, P.1    Xu, B.2    Spokas, E.3    Lai, P.S.4    Wong, P.Y.5
  • 13
    • 0033610282 scopus 로고    scopus 로고
    • Beneficial effects of inducible nitric oxide synthase inhibitor on reperfusion injury in the pig liver
    • Isobe M, Katsuramaki T, Hirata K, Kimura H, Nagayama M, Matsuno T. Beneficial effects of inducible nitric oxide synthase inhibitor on reperfusion injury in the pig liver. Transplantation 1999 68 : 803 13.
    • (1999) Transplantation , vol.68 , pp. 803-13
    • Isobe, M.1    Katsuramaki, T.2    Hirata, K.3    Kimura, H.4    Nagayama, M.5    Matsuno, T.6
  • 16
  • 17
    • 0037093483 scopus 로고    scopus 로고
    • A novel inhibitor of inducible nitric oxide synthase (ONO-1714) prevents critical warm ischemia-reperfusion injury in the pig liver
    • Meguro M, Katsuramaki T, Nagayama M, Kimura H, Isobe M, Kimura Y, Matsuno T, Nui A, Hirata K. A novel inhibitor of inducible nitric oxide synthase (ONO-1714) prevents critical warm ischemia-reperfusion injury in the pig liver. Transplantation 2002 73 : 1439 46.
    • (2002) Transplantation , vol.73 , pp. 1439-46
    • Meguro, M.1    Katsuramaki, T.2    Nagayama, M.3    Kimura, H.4    Isobe, M.5    Kimura, Y.6    Matsuno, T.7    Nui, A.8    Hirata, K.9
  • 18
    • 17144391461 scopus 로고    scopus 로고
    • Remnant liver injury after hepatectomy with the pringle maneuver and its inhibition by an iNOS inhibitor (ONO-1714) in a pig model
    • Kukita K, Katsuramaki T, Kikuchi H, Meguro M, Nagayama M, Kimura H. Remnant liver injury after hepatectomy with the pringle maneuver and its inhibition by an iNOS inhibitor (ONO-1714) in a pig model. J Surg Res 2005 125 : 78 87.
    • (2005) J Surg Res , vol.125 , pp. 78-87
    • Kukita, K.1    Katsuramaki, T.2    Kikuchi, H.3    Meguro, M.4    Nagayama, M.5    Kimura, H.6
  • 19
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990 87 : 1620 4.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-4
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 20
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor WA, Squadrito GL. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol 1995 268 : 699 722.
    • (1995) Am J Physiol , vol.268 , pp. 699-722
    • Pryor, W.A.1    Squadrito, G.L.2
  • 24
    • 0345118244 scopus 로고    scopus 로고
    • Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat
    • Kamanaka Y, Kawabata A, Matsuya H, Taga C, Sekiguchi F, Kawao N. Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat. Life Sci 2003 74 : 793 802.
    • (2003) Life Sci , vol.74 , pp. 793-802
    • Kamanaka, Y.1    Kawabata, A.2    Matsuya, H.3    Taga, C.4    Sekiguchi, F.5    Kawao, N.6
  • 27
    • 0035122655 scopus 로고    scopus 로고
    • Expression patterns of cell cycle-related proteins in a rat cirrhotic model induced by CCl4 or thioacetamide
    • Jeong DH, Jang JJ, Lee SJ, Lee JH, Lim IK, Lee MJ, Lee YS. Expression patterns of cell cycle-related proteins in a rat cirrhotic model induced by CCl4 or thioacetamide. J Gastroenterol 2001 36 : 24 32.
    • (2001) J Gastroenterol , vol.36 , pp. 24-32
    • Jeong, D.H.1    Jang, J.J.2    Lee, S.J.3    Lee, J.H.4    Lim, I.K.5    Lee, M.J.6    Lee, Y.S.7
  • 28
    • 13844271441 scopus 로고    scopus 로고
    • Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor
    • Chida N, Hirasawa Y, Ohkawa T, Ishii Y, Sudo Y, Tamura K, Mutoh S. Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor. Eur J Pharmacol 2005 509 : 71 6.
    • (2005) Eur J Pharmacol , vol.509 , pp. 71-6
    • Chida, N.1    Hirasawa, Y.2    Ohkawa, T.3    Ishii, Y.4    Sudo, Y.5    Tamura, K.6    Mutoh, S.7
  • 30
    • 0023751476 scopus 로고
    • Thioacetamide-induced cirrhosis-like liver lesions in rats - Usefulness and reliability of this animal model
    • Muller A, Machnik F, Zimmermann T, Schubert H. Thioacetamide-induced cirrhosis-like liver lesions in rats - usefulness and reliability of this animal model. Exp Pathol 1988 34 : 229 36.
    • (1988) Exp Pathol , vol.34 , pp. 229-36
    • Muller, A.1    MacHnik, F.2    Zimmermann, T.3    Schubert, H.4
  • 31
    • 0035980914 scopus 로고    scopus 로고
    • Chronic liver injury, TGF-beta, and cancer
    • Bissell DM. Chronic liver injury, TGF-beta, and cancer. Exp Mol Med 2001 33 : 179 90.
    • (2001) Exp Mol Med , vol.33 , pp. 179-90
    • Bissell, D.M.1
  • 32
    • 0032794576 scopus 로고    scopus 로고
    • Cytokines and fibrogenesis
    • Friedman SL. Cytokines and fibrogenesis. Semin Liver Dis 1999 19 : 129 40.
    • (1999) Semin Liver Dis , vol.19 , pp. 129-40
    • Friedman, S.L.1
  • 34
    • 4644257565 scopus 로고    scopus 로고
    • Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice
    • Fiorucci S, Antonelli E, Distrutti E, Mencarelli A, Farneti S, Del Soldato P, Morelli A. Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice. Br J Pharmacol 2004 143 : 33 42.
    • (2004) Br J Pharmacol , vol.143 , pp. 33-42
    • Fiorucci, S.1    Antonelli, E.2    Distrutti, E.3    Mencarelli, A.4    Farneti, S.5    Del Soldato, P.6    Morelli, A.7
  • 35
    • 0347906012 scopus 로고    scopus 로고
    • A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats
    • Loureiro-Silva MR, Cadelina GW, Iwakiri Y, Groszmann R. A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats. J Hepatol 2003 39 : 940 6.
    • (2003) J Hepatol , vol.39 , pp. 940-6
    • Loureiro-Silva, M.R.1    Cadelina, G.W.2    Iwakiri, Y.3    Groszmann, R.4
  • 36
    • 0033852205 scopus 로고    scopus 로고
    • Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells
    • Zhuang S, Simon G. Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells. Am J Physiol Cell Physiol 2000 279 : C341 51.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Zhuang, S.1    Simon, G.2
  • 38
    • 0036749813 scopus 로고    scopus 로고
    • Differential expression and localization of nitric oxide synthases in cirrhotic livers of bile duct-ligated rats
    • Wei CL, Khoo HE, Lee KH, Hon WM. Differential expression and localization of nitric oxide synthases in cirrhotic livers of bile duct-ligated rats. Nitric Oxide 2002 7 : 91 102.
    • (2002) Nitric Oxide , vol.7 , pp. 91-102
    • Wei, C.L.1    Khoo, H.E.2    Lee, K.H.3    Hon, W.M.4
  • 40
    • 19944428400 scopus 로고    scopus 로고
    • Antiviral therapy for cirrhotic hepatitis C: Association with reduced hepatocellular carcinoma development and improved survival
    • Shiratori Y, Ito Y, Yokosuka O, Imazeki F, Nakata R, Tanaka N. Antiviral therapy for cirrhotic hepatitis C: association with reduced hepatocellular carcinoma development and improved survival. Ann Intern Med 2005 142 : 105 14.
    • (2005) Ann Intern Med , vol.142 , pp. 105-14
    • Shiratori, Y.1    Ito, Y.2    Yokosuka, O.3    Imazeki, F.4    Nakata, R.5    Tanaka, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.