Antioxidant vitamins and adrenocorticotrophic hormone-induced hypertension in rats

Clinical and Experimental Hypertension

Volumn 29, Issue 7, 2007, Pages 465-478

  Schyvens, Christopher G ^a   Andrews, Miles C ^a   Tam, Rachel ^a   Mori, Trevor A ^b   Croft, Kevin D ^b   McKenzie, Katja U S ^a   Whitworth, Judith A ^a   Zhang, Yi ^a  

^a Biology and Environment   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Ascorbic acid; Hypertension; Tocopherol

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CORTICOTROPIN; GAMMA TOCOPHEROL; ISOPROSTANE DERIVATIVE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; TAP WATER; VITAMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; DIET SUPPLEMENTATION; HYPERTENSION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SYSTOLIC BLOOD PRESSURE;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; DISEASE MODELS, ANIMAL; HYPERTENSION; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SYSTOLE; TOCOPHEROLS; VITAMINS;

EID: 36248948591     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.1080/10641960701615774     Document Type: Article

References (44)

1. Whitworth JA, Schyvens CG, Zhang Y, Mangos GJ, Kelly JJ. Glucocorticoid-induced hypertension: from mouse to man. Clin Exp Pharmacol Physiol. 2001;28:993-996.
2. Whitworth JA, Schyvens CG, Zhang Y, Andrews MC, Mangos GJ, Kelly J. The nitric oxide system in glucocorticoid-induced hypertension. J Hypertens. 2002;20:1035-1043.
3. Zhang Y, Jang R, Mori TA, Croft KD, Schyvens CG, McKenzie KUS, Whitworth JA. The antioxidant tempol reverses and partially prevents adrenocorticotropic hormone-induced hypertension in the rat. J Hypertens. 2003;21:1613-1618.
4. Zhang Y, Croft KD, Mori TA, Schyvens CG, McKenzie KUS, Whitworth JA. The anti-oxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat. Am J Hypertens. 2004;17:260-265.
5. Zhang Y, Chan MMK, Andrews MC, Mori TA, Croft KD, McKenzie KUS, Schyvens CG, Whitworth JA. Apocynin but not allopurinol prevents and reverses ACTH-induced hypertension in the rat. Am J Hypertens. 2005;18:910-916.
6. Hu L, Zhang Y, Lim PS, Miao Y, Tan C, McKenzie KUS, Schyvens CG, Whitworth JA. Apocynin but not L-arginine prevents and reverses dexamethasone-induced hypertension in the rat. Am J Hypertens. 2006;19:413-418.
7. Mondo CK, Zhang Y, Possamai V, Miao Y, Schyvens CG, McKenzie KUS, Hu L, Guo Z, Whitworth JA. N-acetylcysteine partially prevents but does not reverse ACTH-induced hypertension in the rat. Clin Exp Hypertens. 2006;28:73-84.
8. Vaziri ND, Ni Z, Oveisi F, Trnavsky-Hobbs DL. Effect of antioxidant therapy on blood pressure and NO synthase expression in hypertension in rats. Hypertension 2000;36:957-964.
9. Iuchi T, Akaike A, Mitsui T, Ohshima Y, Shintani Y, Azuma H, Matsumoto T. Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction. Circ Res. 2003;92:81-87.
10. Mangos GJ, Turner SW, Fraser TB, Whitworth JA. The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. J Hypertens. 2000;18:1849-1855.
11. Turner SW, Wen C, Li M, Whitworth JA L-arginine prevents corticotropin-induced increases in blood pressure in the rat. Hypertension 1996;27:184-189.
12. Wen C, Li M, Fraser T, Wang J, Turner SW, Whitworth JA. L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat. Blood Pressure 2000;9:298-304.
13. Wen C, Li M, Whitworth JA. Role of nitric oxide in adrenocorticotrophin- induced hypertension: L-arginine effects reversed by N-nitro-L-arginine. Clin Exp Pharmacol Physiol. 2000;27:887-890.
14. Olsson B, Johansson M, Gabrielsson J, Bolme P. Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine. Eur J Clin Pharmacol 1988;34:77-82.
15. Touyz RM. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? Hypertension 2004;44:1-5.
16. McCall MR, Frei B. Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic Biol Med. 1999;26:1034-1053.
17. Block G, Mangels AR, Norkus EP, Patterson BH, Levander OA, Taylor PR. Ascorbic acid status and subsequent diastolic and systolic blood pressure. Hypertension 2001;37:261-267.
18. Chen J, He J, Hamm L, Batuman V, Whelton PK. Serum antioxidant vitamins and blood pressure in the United States population. Hypertension 2002;40:810-816.
19. Heart Protection Study Collaboration Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002;360:23-33.
20. Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003;22:18-35.
21. Houston MC. Nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension. Prog Cardiovasc Dis. 2005;47:396-449.
22. Brigelius-Flohe R, Traber MG. Vitamin E: function and metabolism. FASEB. 1999;13:1145-1155.
23. Hensley K, Benaksas EJ, Bolli R, Comp P, Grammas P, Hamdheydari L, Mou S, Pye QN, Stoddard MF, Wallis G, Williamson KS, West M, Wechter WJ, Floyd RA. New perspectives on Vitamin E: γ-tocopherol and carboxyethylhydroxychroman metabolites in biology and medicine. Free Rad Biol Med. 2004;36:1-15.
24. Moshage H, Kok B, Huizenga J, Jansen P. Nitrite and nitrate determination in plasma: a critical evaluation. Clin Chem. 1995;41:892-896.
25. Lee W, Hamernyik P, Hutchinson M, Raisys VA, Labbe RF. Ascorbic acid in lymphocytes: cell preparation and liquid-chromatography assay. Clin Chem. 1982;28:2165-2169.
26. Nilsson B, Johansson B, Jansson L, Holmberg L. Determination of plasma alpha-tocopherol by high-performance liquid chromatography. J Chromatogr. 1978;145:169-172.
27. Greggi Antunes LM, Darin JD, Bianchi MD. Protective effects of vitamin C against cisplatininduced nephrotoxicity and lipid peroxidation in adult rats: a dose-dependent study. Pharmacol Res. 2000;41:405-411.
28. Lutz M, Cortez J, Vinet R. Effects of dietary fats, alpha-tocopherol and beta-carotene supplementation on aortic ring segment responses in the rat. Int J Vitam Nutr Res. 1995;65:225-230.
29. Clement M, Bourre JM. Graded dietary levels of RRR-gamma-tocopherol induce a marked increase in the concentrations of alpha- and gamma-tocopherol in nervous tissues, heart, liver and muscle of vitamin E-deficient rats. Biochim Biophys Acta. 1997;1334:173-181.
30. Seo MY, Lee SM. Protective effect of low dose of ascorbic acid on hepatobiliary function in hepatic ischemia/reperfusion in rats. J Hepatol. 2002;36:72-77.
31. Chen X, Touyz RM, Park JB, Schiffrin EL. Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR. Hypertension 2001;38:606-611.
32. Akpaffiong MJ, Taylor AA. Antihypertensive and vasodilator actions of antioxidants in spontaneously hypertensive rats. Am J Hypertens. 1998;11:1450-1460.
33. Schafer SC, Wallerath T, Closs EI, Schmidt C, Schwarz PM, Forstermann U, Lehr HA. Dexamethasone suppresses eNOS and CAT-1 and induces oxidative stress in mouse resistance arterioles. Am J Physiol Heart Circ Physiol. 2005;288:H436-H444. Erratum in: Am J Physiol Heart Circ Physiol. 2005;289:H2752.
34. Kim MK, Sasaki S, Sasazuki S, Okubo S, Hayashi M, Tsugane S. Lack of long-term effect of vitamin C supplementation on blood pressure. Hypertension 2002;40:797-803.
35. Saldeen T, Li D, Mehta JL. Differential effects of α- and γ-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis. J Am Coll Cardiol. 1999;34:1208-1215.
36. Li D, Saldeen T, Romero F, Mehta JL. Relative effects of α- and γ-tocopherol on low-density lipoprotein oxidation and superoxide dismutase and nitric oxide synthase activity and protein expression in rats. J Cardiovasc Pharmacol Therapeut. 1999;4:219-226.
37. Newaz MA, Nawal NN, Rohaizan CH, Muslim N, Gapor A. Alpha-tocopherol increased nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats. Am J Hypertens. 1999;12:839-844.
38. Newaz MA, Nawal NN. Effect of alpha-tocopherol on lipid peroxidation and total antioxidant status in spontaneously hypertensive rats. Am J Hypertens. 1998;11:1480-1485.
39. Noguchi T, Ikeda K, Sasaki Y, Yamamoto J, Yamori Y. Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2004;31 (Suppl. 2):S24-S26.
40. Forde P, Scribner AW, Dial R, Loscalzo J, Trolliet MR. Prevention of hypertension and renal dysfunction in Dahl rats by alpha-tocopherol. J Cardiovasc Pharmacol. 2003;42:82-88.
41. Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:154-160.
42. Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet. 2003;361:2017-2023. Erratum in: Lancet 2004 21;363:662.
43. Miller ER III, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142:37-46.
44. Maffei A, Poulet R, Vecchione C, Colella S, Fratta L, Frati G, Trimarco V, Trimarco B, Lembo G. Increased basal nitric oxide release despite enhanced free radical production in hypertension. J Hypertens. 2002;20:1135-1142.