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Volumn 288, Issue 1 57-1, 2005, Pages

Dexamethasone suppresses eNOS and CAT-1 and induces oxidative stress in mouse resistance arterioles

Author keywords

Cationic amino acid transporter 1; Endothelial nitric oxide synthase; Glucocorticoids; Hypertension; Intravital microscopy; L arginine; Reactive oxygen species

Indexed keywords

AMINO ACID TRANSPORTER; ARGININE; DEXAMETHASONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOCORTICOID; MINERALOCORTICOID; N ACETYL S NITROSOPENICILLAMINE; REACTIVE OXYGEN METABOLITE;

EID: 11144256975     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00587.2004     Document Type: Article
Times cited : (92)

References (50)
  • 1
    • 0003398975 scopus 로고
    • Washington, DC: Federation of American Societies for Experimental Biology
    • Altman PL. Biological Handbooks: Blood and Other Body Fluids. Washington, DC: Federation of American Societies for Experimental Biology, 1961, p. 75-78.
    • (1961) Biological Handbooks: Blood and Other Body Fluids , pp. 75-78
    • Altman, P.L.1
  • 2
    • 0034171336 scopus 로고    scopus 로고
    • Quantification of video-taped images in microcirculation research using inexpensive imaging software (Adobe Photoshop)
    • Brunner J, Krummenauer F, and Lehr HA. Quantification of video-taped images in microcirculation research using inexpensive imaging software (Adobe Photoshop). Microcirculation 7: 103-107, 2000.
    • (2000) Microcirculation , vol.7 , pp. 103-107
    • Brunner, J.1    Krummenauer, F.2    Lehr, H.A.3
  • 4
    • 0027368884 scopus 로고
    • Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats
    • Chen PY and Sanders PW. Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats. Hypertension 22: 812-818, 1993.
    • (1993) Hypertension , vol.22 , pp. 812-818
    • Chen, P.Y.1    Sanders, P.W.2
  • 5
    • 0027409441 scopus 로고
    • Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver
    • Closs EI, Albritton LM, Kim JW, and Cunningham JM. Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver. J Biol Chem 268: 7538-7544, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 7538-7544
    • Closs, E.I.1    Albritton, L.M.2    Kim, J.W.3    Cunningham, J.M.4
  • 6
    • 0342506444 scopus 로고    scopus 로고
    • Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: Three related carriers with distinct transport properties
    • Closs EI, Graef P, Habermeier A, Cunningham JM, and Foerstermann U. Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry 36: 6462-6468, 1997.
    • (1997) Biochemistry , vol.36 , pp. 6462-6468
    • Closs, E.I.1    Graef, P.2    Habermeier, A.3    Cunningham, J.M.4    Foerstermann, U.5
  • 7
    • 0033986606 scopus 로고    scopus 로고
    • Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: Role of cationic amino acid transporters
    • Closs EI, Scheld JS, Sharafi M, and Foerstermann U. Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters. Mol Pharmacol 57: 68-74, 2000.
    • (2000) Mol Pharmacol , vol.57 , pp. 68-74
    • Closs, E.I.1    Scheld, J.S.2    Sharafi, M.3    Foerstermann, U.4
  • 8
    • 0032989206 scopus 로고    scopus 로고
    • Pentobarbital-sensitive EDHF comediates ACh-induced arteriolar dilation in the hamster microcirculation
    • De Wit C, Esser N, Lehr HA, Bolz SS, and Pohl U. Pentobarbital-sensitive EDHF comediates ACh-induced arteriolar dilation in the hamster microcirculation. Am J Physiol Heart Circ Physiol 276: H1527-H1534, 1999.
    • (1999) Am J Physiol Heart Circ Physiol , vol.276
    • De Wit, C.1    Esser, N.2    Lehr, H.A.3    Bolz, S.S.4    Pohl, U.5
  • 9
    • 0030227168 scopus 로고    scopus 로고
    • Selective induction of a cationic amino acid transporter by tumor necrosis factor-alpha in vascular endothelium
    • Durante W, Liao L, Cheng K, and Schafer AI. Selective induction of a cationic amino acid transporter by tumor necrosis factor-alpha in vascular endothelium. Proc Assoc Am Physicians 108: 356-361, 1996.
    • (1996) Proc Assoc Am Physicians , vol.108 , pp. 356-361
    • Durante, W.1    Liao, L.2    Cheng, K.3    Schafer, A.I.4
  • 10
    • 1642562661 scopus 로고    scopus 로고
    • Treatment of glomerular endothelial dysfunction in steroid-resistant nephrosis with Ganoderma lucidum, vitamins C, E and vasodilators
    • Futrakul N, Boonyen M, Patumraj S, Siriviriyakul P, Tosukhowong P, and Futrakul P. Treatment of glomerular endothelial dysfunction in steroid-resistant nephrosis with Ganoderma lucidum, vitamins C, E and vasodilators. Clin Hemorheol Microcirc 29: 205-210, 2003.
    • (2003) Clin Hemorheol Microcirc , vol.29 , pp. 205-210
    • Futrakul, N.1    Boonyen, M.2    Patumraj, S.3    Siriviriyakul, P.4    Tosukhowong, P.5    Futrakul, P.6
  • 11
    • 0023216508 scopus 로고
    • Chemical renal medullectomy prevents frusemide-induced inhibition of sympathetic vasoconstriction in the in situ blood perfused rat mesentery
    • Gerkens JF, Armsworth SJ, Bhagwandeen SB, and Smith AJ. Chemical renal medullectomy prevents frusemide-induced inhibition of sympathetic vasoconstriction in the in situ blood perfused rat mesentery. J Hypertens 5: 273-275, 1987.
    • (1987) J Hypertens , vol.5 , pp. 273-275
    • Gerkens, J.F.1    Armsworth, S.J.2    Bhagwandeen, S.B.3    Smith, A.J.4
  • 12
    • 0027197086 scopus 로고
    • Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: An epidemiological update with special attention to carotene and vitamin C
    • Gey KF, Moser UK, Jordan P, Stahelin HB, Eichholzer M, and Ludin E. Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C. Am J Clin Nutr 57: 787S-797S, 1993.
    • (1993) Am J Clin Nutr , vol.57
    • Gey, K.F.1    Moser, U.K.2    Jordan, P.3    Stahelin, H.B.4    Eichholzer, M.5    Ludin, E.6
  • 14
    • 0033063539 scopus 로고    scopus 로고
    • Cationic amino acid transporter gene expression in cultured vascular smooth muscle cells and in rats
    • Hattori Y, Kasai K, and Gross SS. Cationic amino acid transporter gene expression in cultured vascular smooth muscle cells and in rats. Am J Physiol Heart Circ Physiol 276: H2020-H2028, 1999.
    • (1999) Am J Physiol Heart Circ Physiol , vol.276
    • Hattori, Y.1    Kasai, K.2    Gross, S.S.3
  • 17
    • 0033854745 scopus 로고    scopus 로고
    • Propofol attenuates acetylcholine-induced pulmonary vasorelaxation: Role of nitric oxide and endothelium-derived hyperpolarizing factors
    • Horibe M, Ogawa K, Sohn JT, and Murray PA. Propofol attenuates acetylcholine-induced pulmonary vasorelaxation: role of nitric oxide and endothelium-derived hyperpolarizing factors. Anesthesiology 93: 447-455, 2000.
    • (2000) Anesthesiology , vol.93 , pp. 447-455
    • Horibe, M.1    Ogawa, K.2    Sohn, J.T.3    Murray, P.A.4
  • 19
    • 0037428173 scopus 로고    scopus 로고
    • Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction
    • Iuchi T, Akaike M, Mitsui T, Ohshima Y, Shintani Y, Azuma H, and Matsumoto T. Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction. Circ Res 92: 81-87, 2003.
    • (2003) Circ Res , vol.92 , pp. 81-87
    • Iuchi, T.1    Akaike, M.2    Mitsui, T.3    Ohshima, Y.4    Shintani, Y.5    Azuma, H.6    Matsumoto, T.7
  • 21
    • 0025784145 scopus 로고
    • Transport of cationic amino acids by the mouse ecotropic retrovirus receptor
    • Kim JW, Closs EI, Albritton LM, and Cunningham JM. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 352: 725-728, 1991.
    • (1991) Nature , vol.352 , pp. 725-728
    • Kim, J.W.1    Closs, E.I.2    Albritton, L.M.3    Cunningham, J.M.4
  • 22
    • 0029115228 scopus 로고
    • Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation
    • Kuo L, Davis MJ, and Chilian WM. Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation. Circulation 92: 518-525, 1995.
    • (1995) Circulation , vol.92 , pp. 518-525
    • Kuo, L.1    Davis, M.J.2    Chilian, W.M.3
  • 23
    • 0028018112 scopus 로고
    • Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo
    • Lehr HA, Frei B, and Arfors KE. Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo. Proc Natl Acad Sci USA 91: 7688-7692, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7688-7692
    • Lehr, H.A.1    Frei, B.2    Arfors, K.E.3
  • 24
    • 0027286346 scopus 로고
    • Stimulation of leukocyte/endothelium interaction by oxidized low-density lipoprotein in hairless mice. Involvement of CD11b/CD 18 adhesion receptor complex
    • Lehr HA, Kroeber M, Huebner C, Vajkoczy P, Menger MD, Nolte D, Kohlschuetter A, and Messmer K. Stimulation of leukocyte/endothelium interaction by oxidized low-density lipoprotein in hairless mice. Involvement of CD11b/CD18 adhesion receptor complex. Lab Invest 68: 388-395, 1993.
    • (1993) Lab Invest , vol.68 , pp. 388-395
    • Lehr, H.A.1    Kroeber, M.2    Huebner, C.3    Vajkoczy, P.4    Menger, M.D.5    Nolte, D.6    Kohlschuetter, A.7    Messmer, K.8
  • 25
    • 0027857106 scopus 로고
    • Dorsal skinfold chamber technique for intravital microscopy in nude mice
    • Lehr HA, Leunig M, Menger MD, Nolte D, and Messmer K. Dorsal skinfold chamber technique for intravital microscopy in nude mice. Am J Pathol 143: 1055-1062, 1993.
    • (1993) Am J Pathol , vol.143 , pp. 1055-1062
    • Lehr, H.A.1    Leunig, M.2    Menger, M.D.3    Nolte, D.4    Messmer, K.5
  • 26
    • 0342723791 scopus 로고    scopus 로고
    • Nitric oxide in the pathogenesis of vascular disease
    • Li H and Foerstermann U. Nitric oxide in the pathogenesis of vascular disease. J Pathol 190: 244-254, 2000.
    • (2000) J Pathol , vol.190 , pp. 244-254
    • Li, H.1    Foerstermann, U.2
  • 27
    • 0036430356 scopus 로고    scopus 로고
    • Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs
    • Li H, Wallerath T, Muenzel T, and Foerstermann U. Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs. Nitric Oxide 7: 149-164, 2002.
    • (2002) Nitric Oxide , vol.7 , pp. 149-164
    • Li, H.1    Wallerath, T.2    Muenzel, T.3    Foerstermann, U.4
  • 28
    • 0030953321 scopus 로고    scopus 로고
    • Dexamethasone-induced hypertension in the rat: Effects of L-arginine
    • Li M, Fraser T, Wang J, and Whitworth JA. Dexamethasone-induced hypertension in the rat: effects of L-arginine. Clin Exp Pharmacol Physiol 24: 730-732, 1997.
    • (1997) Clin Exp Pharmacol Physiol , vol.24 , pp. 730-732
    • Li, M.1    Fraser, T.2    Wang, J.3    Whitworth, J.A.4
  • 29
    • 0028926105 scopus 로고
    • Vasodilatory effects of ketamine on pulmonary arteries in rats with chronic hypoxic pulmonary hypertension
    • Maruyama K, Maruyama J, Yokochi A, Muneyuki M, and Miyasaka K. Vasodilatory effects of ketamine on pulmonary arteries in rats with chronic hypoxic pulmonary hypertension. Anesth Analg 80: 786-792, 1995.
    • (1995) Anesth Analg , vol.80 , pp. 786-792
    • Maruyama, K.1    Maruyama, J.2    Yokochi, A.3    Muneyuki, M.4    Miyasaka, K.5
  • 30
    • 0027482749 scopus 로고
    • Scope and perspectives of intravital microscopy-bridge over from in vitro to in vivo
    • Menger MD and Lehr HA. Scope and perspectives of intravital microscopy-bridge over from in vitro to in vivo. Immunol Today 14: 519-522, 1993.
    • (1993) Immunol Today , vol.14 , pp. 519-522
    • Menger, M.D.1    Lehr, H.A.2
  • 32
    • 0025080602 scopus 로고
    • Structure and function of small arteries
    • Mulvany MJ and Aalkjaer C. Structure and function of small arteries. Physiol Rev 70: 921-961, 1990.
    • (1990) Physiol Rev , vol.70 , pp. 921-961
    • Mulvany, M.J.1    Aalkjaer, C.2
  • 33
    • 0035199632 scopus 로고    scopus 로고
    • Cytokine treatment increases arginine metabolism and uptake in bovine pulmonary arterial endothelial cells
    • Nelin LD, Nash HE, and Chicoine LG. Cytokine treatment increases arginine metabolism and uptake in bovine pulmonary arterial endothelial cells. Am J Physiol Lung Cell Mol Physiol 281: L1232-L1239, 2001.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Nelin, L.D.1    Nash, H.E.2    Chicoine, L.G.3
  • 34
    • 0029878479 scopus 로고    scopus 로고
    • Contrasting effects of blockade of nitric oxide formation on resistance and conductance coronary vessels in conscious dogs
    • Parent R, Hamdad N, Ming Z, and Lavallee M. Contrasting effects of blockade of nitric oxide formation on resistance and conductance coronary vessels in conscious dogs. Cardiovasc Res 31: 555-567, 1996.
    • (1996) Cardiovasc Res , vol.31 , pp. 555-567
    • Parent, R.1    Hamdad, N.2    Ming, Z.3    Lavallee, M.4
  • 35
    • 0034115831 scopus 로고    scopus 로고
    • Large arterioles in the control of blood flow: Role of endothelium-dependent dilation
    • Pohl U, De Wit C, and Gloe T. Large arterioles in the control of blood flow: role of endothelium-dependent dilation. Acta Physiol Scand 168: 505-510, 2000.
    • (2000) Acta Physiol Scand , vol.168 , pp. 505-510
    • Pohl, U.1    De Wit, C.2    Gloe, T.3
  • 36
    • 0025750850 scopus 로고
    • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells
    • Pollock JS, Foerstermann U, Mitchell JA, Warner TD, Schmidt HH, Nakane M, and Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci USA 88: 10480-10484, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10480-10484
    • Pollock, J.S.1    Foerstermann, U.2    Mitchell, J.A.3    Warner, T.D.4    Schmidt, H.H.5    Nakane, M.6    Murad, F.7
  • 38
    • 0025695687 scopus 로고
    • Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: An insight into endotoxin shock
    • Rees DD, Cellek S, Palmer RM, and Moncada S. Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: an insight into endotoxin shock. Biochem Biophys Res Commun 173: 541-547, 1990.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 541-547
    • Rees, D.D.1    Cellek, S.2    Palmer, R.M.3    Moncada, S.4
  • 39
    • 0026680275 scopus 로고
    • Renal effects of prolonged synthesis inhibition of endothelium-derived nitric oxide
    • Salazar FJ, Pinilla JM, Lopez F, Romero JC, and Quesada T. Renal effects of prolonged synthesis inhibition of endothelium-derived nitric oxide. Hypertension 20: 113-117, 1992.
    • (1992) Hypertension , vol.20 , pp. 113-117
    • Salazar, F.J.1    Pinilla, J.M.2    Lopez, F.3    Romero, J.C.4    Quesada, T.5
  • 40
    • 0029880571 scopus 로고    scopus 로고
    • Mechanism of glucocorticoid-induced hypertension
    • Saruta T. Mechanism of glucocorticoid-induced hypertension. Hypertens Res 19: 1-8, 1996.
    • (1996) Hypertens Res , vol.19 , pp. 1-8
    • Saruta, T.1
  • 41
    • 0035339278 scopus 로고    scopus 로고
    • Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA
    • Schwartz IF, Schwartz D, Wollman Y, Chernichowski T, Blum M, Levo Y, and Iaina A. Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA. J Lab Clin Med 137: 356-362, 2001.
    • (2001) J Lab Clin Med , vol.137 , pp. 356-362
    • Schwartz, I.F.1    Schwartz, D.2    Wollman, Y.3    Chernichowski, T.4    Blum, M.5    Levo, Y.6    Iaina, A.7
  • 42
    • 0029793534 scopus 로고    scopus 로고
    • Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport
    • Simmons WW, Ungureanu-Longrois D, Smith GK, Smith TW, and Kelly RA. Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport. J Biol Chem 271: 23928-23937, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 23928-23937
    • Simmons, W.W.1    Ungureanu-Longrois, D.2    Smith, G.K.3    Smith, T.W.4    Kelly, R.A.5
  • 45
    • 0029055276 scopus 로고
    • In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats: Hydroethidine microfluorography
    • Suzuki H, Swei A, Zweifach BW, and Schmid-Schonbein GW. In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats: hydroethidine microfluorography. Hypertension 25: 1083-1089, 1995.
    • (1995) Hypertension , vol.25 , pp. 1083-1089
    • Suzuki, H.1    Swei, A.2    Zweifach, B.W.3    Schmid-Schonbein, G.W.4
  • 46
    • 0028893458 scopus 로고
    • Modification of leukocyte adhesion in spontaneously hypertensive rats by adrenal corticosteroids
    • Suzuki H, Zweifach BW, Forrest MJ, and Schmid-Schonbein GW. Modification of leukocyte adhesion in spontaneously hypertensive rats by adrenal corticosteroids. J Leukoc Biol 57: 20-26, 1995.
    • (1995) J Leukoc Biol , vol.57 , pp. 20-26
    • Suzuki, H.1    Zweifach, B.W.2    Forrest, M.J.3    Schmid-Schonbein, G.W.4
  • 47
    • 0029402648 scopus 로고
    • Dependence of elevated mesenteric arteriolar tone on glucocorticoids in spontaneously hypertensive rats
    • Suzuki H, Zweifach BW, and Schmid-Schonbein GW. Dependence of elevated mesenteric arteriolar tone on glucocorticoids in spontaneously hypertensive rats. Int J Microcirc Clin Exp 15: 309-315, 1995.
    • (1995) Int J Microcirc Clin Exp , vol.15 , pp. 309-315
    • Suzuki, H.1    Zweifach, B.W.2    Schmid-Schonbein, G.W.3
  • 48
    • 0030029686 scopus 로고    scopus 로고
    • Glucocorticoid modulates vasodilator response of mesenteric arterioles in spontaneously hypertensive rats
    • Suzuki H, Zweifach BW, and Schmid-Schonbein GW. Glucocorticoid modulates vasodilator response of mesenteric arterioles in spontaneously hypertensive rats. Hypertension 27: 114-118, 1996.
    • (1996) Hypertension , vol.27 , pp. 114-118
    • Suzuki, H.1    Zweifach, B.W.2    Schmid-Schonbein, G.W.3
  • 49
    • 0029558290 scopus 로고
    • Dexamethasone influences intimal thickening and vascular reactivity in the rabbit collared carotid artery
    • Van Put DJ, Van Hove CE, De Meyer GR, Wuyts F, Herman AG, and Bull H. Dexamethasone influences intimal thickening and vascular reactivity in the rabbit collared carotid artery. Eur J Pharmacol 294: 753-761, 1995.
    • (1995) Eur J Pharmacol , vol.294 , pp. 753-761
    • Van Put, D.J.1    Van Hove, C.E.2    De Meyer, G.R.3    Wuyts, F.4    Herman, A.G.5    Bull, H.6


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