Changes in immunoreactivity of HSP60 and its neuroprotective effects in the gerbil hippocampal CA1 region induced by transient ischemia

Experimental Neurology

Volumn 208, Issue 2, 2007, Pages 247-256

  Hwang, In Koo ^a   Ahn, Hee Cheol ^b,c   Yoo, Ki Yeon ^c   Lee, Jae Yong ^c   Suh, Hong Won ^c,d   Kwon, Young Guen ^e   Cho, Jun Hwi ^b   Won, Moo Ho ^c  

^a Seoul National University   (South Korea)

^b Kangwon National University   (South Korea)

^c Hallym University   (South Korea)

^d Hallym University   (South Korea)

^e Yonsei University   (South Korea)

Author keywords

Adenoviral vector; Delayed neuronal death; Hippocampal CA1 region; HSP60; Neuroprotection; Transient ischemia

Indexed keywords

BRAIN PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; HEAT SHOCK PROTEIN 60;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN DAMAGE; BRAIN ISCHEMIA; BRAIN REGION; CELL PROTECTION; CONTROLLED STUDY; FOREBRAIN; GERBIL; GLIA CELL; HIPPOCAMPUS; IMMUNOREACTIVITY; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; REPERFUSION; TRANSIENT ISCHEMIC ATTACK; VIRUS RECOMBINANT; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; CELL DEATH; CHAPERONIN 60; FLUORESCENT ANTIBODY TECHNIQUE; GERBILLINAE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; PYRAMIDAL CELLS; STAINING AND LABELING; TISSUE DISTRIBUTION;

EID: 36049022492     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.08.017     Document Type: Article

References (43)

1. Abe K., Kawagoe J., Aoki M., and Kogure K. Changes of mitochondrial DNA and heat shock protein gene expressions in gerbil hippocampus after transient forebrain ischemia. J. Cereb. Blood Flow Metab. 13 (1993) 773-780
2. Abe K., Kawagoe J., Itoyama Y., and Kogure K. Isolation of an ischemia-induced gene and early disturbance of mitochondrial DNA expression after transient forebrain ischemia. Adv. Neurol. 71 (1996) 485-503
3. Abe K., Kawagoe J., Aoki M., Kogure K., and Itoyama Y. Stress protein inductions after brain ischemia. Cell. Mol. Neurobiol. 18 (1998) 709-719
4. Anderson C.M., and Nedergaard M. Astrocyte-mediated control of cerebral microcirculation. Trends Neurosci. 26 (2003) 340-344
5. Bajramović J.J., Geutskens S.B., Bsibsi M., Boot M., Hassankhan R., Verhulst K.C., and van Noort J.M. The stress kit: a new method based on competitive reverse transcriptase-polymerase chain reaction to quantify the expression of human alphaB-crystallin, Hsp27, and Hsp60. Cell Stress Chaperones 5 (2000) 30-35
6. Beckmann R.P., Lovett M., and Welch W.J. Examining the function and regulation of shp70 in cells subjected to metabolic stress. J. Cell Biol. 117 (1992) 1137-1159
7. Buttke T.M., and Sandstrom P.A. Oxidative stress as a mediator of apoptosis. Immunol. Today 15 (1994) 7-10
8. Candelario-Jalil E., Alvarez D., Merino N., and Leon O.S. Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils. Neurosci. Res. 47 (2003) 245-253
9. Christophe M., and Nicolas S. Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion. Curr. Pharm. Des. 12 (2006) 739-757
10. Craig E.A., Kramer J., Shilling J., Werner-Washburne M., Holmes S., Kosic-Smithers J., and Nicolet C.M. SSC1, an essential member of the yeast HSP70 multigene family, encodes a mitochondrial protein. Mol. Cell. Biol. 9 (1989) 3000-3008
11. Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 82 (2002) 47-95
12. Frantseva M.V., Carlen P.L., and Perez Velazquez J.L. Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons. Free Radic. Biol. Med. 31 (2001) 1216-1227
13. Gething M.J., and Sambrook J. Protein folding in the cell. Nature 355 (1992) 33-35
14. Hald A., and Lotharius J. Oxidative stress and inflammation in Parkinson's disease: is there a causal link?. Exp. Neurol. 193 (2005) 279-290
15. Hartl F.U. Heat shock proteins in protein folding and membrane translocation. Semin. Immunol. 3 (1991) 5-16
16. Hou Q., and Hsu Y.T. Bax translocates from cytosol to mitochondria in cardiac cells during apoptosis: development of a GFP-Bax-stable H9c2 cell line for apoptosis analysis. Am. J. Physiol, Heart Circ. Physiol. 289 (2005) H477-H487
17. Hwang I.K., Eum W.S., Yoo K.Y., Cho J.H., Kim D.W., Choi S.H., Kang T.C., Kwon O.S., Kang J.H., Choi S.Y., and Won M.H. Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus. Free Radic. Biol. Med. 39 (2005) 392-402
18. Hwang I.K., Yoo K.Y., Nam Y.S., Choi J.H., Lee I.S., Kwon Y.G., Kang T.C., Kim Y.S., and Won M.H. Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult. Neurosci. Res. 54 (2006) 319-327
19. Itoh H., Kobayashi R., Wakui H., Komatsuda A., Ohtani H., Miura A.B., Otaka M., Masamune O., Andoh H., Koyama K., Sata Y., and Tashima Y. Mammalian 60-kDa stress protein (chaperonin homolog). Identification, biochemical properties, and localization. J. Biol. Chem. 270 (1995) 13429-13435
20. Jacobson M.D. Reactive oxygen species and programmed cell death. Trends Biochem. Sci. 21 (1996) 83-86
21. Kim S.W., and Lee J.K. NO-induced downregulation of HSP10 and HSP60 expression in the postischemic brain. J. Neurosci. Res. 85 (2007) 1252-1259
22. Kirchhoff S.R., Gupta S., and Knowlton A.A. Cytosolic heat shock protein 60, apoptosis, and myocardial injury. Circulation 105 (2002) 2899-2904
23. Lau S., Patnaik N., Sayen M.R., and Mestril R. Simultaneous overexpression of two stress proteins in rat cardiomyocytes and myogenic cells confers protection against ischemia-induced injury. Circulation 96 (1997) 2287-2294
24. Lee M.Y., Choi Y.S., Choi J.S., Min D.S., Chun M.H., Kim O.N., Lee S.B., and Kim S.Y. An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia. Brain Res. 924 (2002) 237-241
25. Lewthwaite J., Owen N., Coates A., Henderson B., and Steptoe A. Circulating human heat shock protein 60 in the plasma of British civil servants: relationship to physiological and psychosocial stress. Circulation 106 (2002) 196-201
26. Li P.A., He Q.P., Nakamura L., and Csiszar K. Free radical spin trap alpha-phenyl-N-tert-butyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury. Free Radic. Biol. Med. 31 (2001) 1191-1197
27. Lin K.M., Lin B., Lian I.Y., Mestril R., Scheffler I.E., and Dillmann W.H. Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation. Circulation 103 (2001) 1787-1792
28. Muranyi M., He Q.P., Fong K.S.K., and Li P.A. Induction of heat shock proteins by hyperglycemic cerebral ischemia. Mol. Brain Res. 139 (2005) 80-87
29. Okubo A., Kinouchi H., Owada Y., Kunizuka H., Itoh H., Izaki K., Kondo H., Tashima Y., Yoshimoto T., and Mizoi K. Simultaneous induction of mitochondrial heat shock protein mRNAs in rat forebrain ischemia. Mol. Brain Res. 84 (2000) 127-134
30. Pelham H.R.B. Speculations on the functions of the major heart shock and glucose-regulated proteins. Cell 46 (1986) 595-561
31. Petito C.K., Torres-Munoz J., Roberts B., Olarte J.P., Nowak Jr. T.S., and Pulsinelli W.A. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. J. Cereb. Blood Flow Metab. 17 (1997) 967-976
32. Pong K., Doctrow S.R., Huffman K., Adinolfi C.A., and Baudry M. Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons. Exp. Neurol. 171 (2001) 84-97
33. Qiao Y., Ouyang Y.B., and Giffard R.G. Overexpression of HDJ-2 protects astrocytes from ischemia-like injury and reduces redistribution of ubiquitin staining in vitro. J. Cereb. Blood Flow Metab. 23 (2003) 1113-1116
34. Rastogi L., Godbole M.M., Ray M., Rathore P., Rathore P., Pradhan S., Gupta S.K., and Pandey C.M. Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult. Exp. Neurol. 200 (2006) 290-300
35. Samali A., Cai J., Zhivotovsky B., Jones D.P., and Orrenius S. Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells. EMBO J. 18 (1999) 2040-2048
36. Schmued L.C., and Hopkins K.J. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 874 (2000) 123-130
37. Shan Y.X., Liu T.J., Su H.F., Samsamshariat A., Mestril R., and Wang P.H. Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells. J. Mol. Cell. Cardiol. 35 (2003) 1135-1143
38. Shigenaga M.K., Hagen T.M., and Ames B.N. Oxidative damage and mitochondrial decay in aging. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10771-10778
39. Solaini G., and Harris D.A. Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion. Biochem. J. 390 (2005) 377-394
40. 2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK. Exp. Neurol. 180 (2003) 144-155
41. Voos W., and Rottgers K. Molecular chaperones as essential mediators of mitochondrial biogenesis. Biochim. Biophys. Acta 1592 (2002) 51-62
42. Yagi T., Jikihara I., Fukumura M., Watabe K., Ohashi T., Eto Y., Hara M., and Maeda M. Rescue of ischemic brain injury by adenoviral gene transfer of glial cell line-derived neurotrophic factor after transient global ischemia in gerbils. Brain Res. 885 (2000) 273-282
43. Zhao Q., Wang J., Levichkin I.V., Stasinopoulos S., Ryan M.T., and Hoogenraad N.J. A mitochondrial specific stress response in mammalian cells. EMBO J. 21 (2002) 4411-4419