Rate-modulating PHBHV/PCL microparticles containing weak acid model drugs

International Journal of Pharmaceutics

Volumn 345, Issue 1-2, 2007, Pages 70-80

  Poletto, Fernanda S ^a   Jäger, Eliézer ^a   Ré, Maria I ^b   Guterres, Sílvia S ^a   Pohlmann, Adriana R ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b Instituto de Pesquisas Tecnologicas   (Brazil)

Author keywords

Diffusion; Drug release; Mathematical modeling; Microparticle; PCL; PHBHV

Indexed keywords

DICLOFENAC; INDOMETACIN; NANOPARTICLE; POLY (HYDROXYBUTYRATE CO HYDROXYVALERATE); POLYCAPROLACTONE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION COEFFICIENT; DRUG DIFFUSION; DRUG HALF LIFE; DRUG RELEASE; DRUG SOLUBILITY; ENCAPSULATION; GLASS TRANSITION TEMPERATURE; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALORIMETRY, DIFFERENTIAL SCANNING; CAPSULES; DICLOFENAC; DRUG COMPOUNDING; HALF-LIFE; INDOMETHACIN; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MODELS, CHEMICAL; MODELS, STATISTICAL; PARTICLE SIZE; POLYESTERS; POROSITY; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; SURFACE PROPERTIES; WATER;

EID: 36049016061     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.05.040     Document Type: Article

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