Nanoparticle-coated microparticles: Preparation and characterization

Journal of Microencapsulation

Volumn 21, Issue 5, 2004, Pages 499-512

  Beck, R C R ^a   Pohlmann, A R ^b   Guterres, S S ^a  

^a Faculdade de Farmacia   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Coating; Diclofenac; Gastroresistance; Microparticles; Nanoparticles; Scanning electron microscopy; Spray drying

Indexed keywords

BUFFER; DICLOFENAC; EUDRAGIT; INORGANIC COMPOUND; NANOCAPSULE; NANOPARTICLE; POLYMER; SILICON DIOXIDE; TRIACETIN;

ARTICLE; BIOTECHNOLOGICAL PRODUCTION; COLLOID; CONTROLLED STUDY; DRUG RELEASE; DRUG STRUCTURE; HYDROPHILICITY; IN VITRO STUDY; MATERIAL COATING; MATERIAL STATE; MICROENCAPSULATION; MICROPARTICLE; PH; POWDER; SPRAY DRYING; STRUCTURE ANALYSIS; SUSPENSION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DICLOFENAC; DRUG COMPOUNDING; HYDROPHOBICITY; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; NANOTECHNOLOGY; TABLETS, ENTERIC-COATED;

EID: 5644259777     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040410001729278     Document Type: Article

References (25)

1. Ammoury, N., Dubrasquet, M., Fessi, H., Devissaguet, J. P., Puisieux, F. and Benita, S., 1993, Indomethacin-loaded poly (D,L-lactide) nanocapsules: protection from gastrointestinal ulcerations and anti-inflammatory activity evaluation in rats. Clinical Materials, 13, 121-130.
2. Benita, S., 1996, Microencapsulation: Methods and Industrial Applications (New York: Marcel Dekker).
3. Bodmeier, R. and Chen, H., 1988, Preparation of biodegradable poly(±)lactide microparticles using a spray-drying technique. Journal of Pharmacy and Pharmacology, 40, 754-757.
4. Chiarini, A., Tartarini, A. and Fini, A., 1984, pH-solubility relationship and partition coefficients for some anti-inflammatory arylaliphatic acids. Archiv der Pharmazie, 317, 268-273.
5. Conte, U., Conti, B., Giunchedi, P. and Maggi, L., 1994, Spray dried polylactide microsphere preparation: influence of the technological parameters. Drug Development and Industrial Pharmacy, 20, 235-258.
6. Fessi, H., Puisieux, F. and Devissaguet, J.-Ph., 1988, European Patent, 0274961 A1.
7. Giunchedi, P., Conti, B., Genta, I., Conte, U. and Puglisi, G., 2001, Emulsion spray-drying for the preparation of albumin-loaded PLGA microspheres. Drug Development and Industrial Pharmacy, 27, 745-750.
8. Guterres, S. S., Fessi, H., Barrat, G., Devissaguet, J.-P., and Puisieux, F., 1995b, Poly(D,L-lactide) nanocapsules containing diclofenac: i. formulation and stability study. International Journal of Pharmaceutics, 113, 57-63.
9. Guterres, S. S., Fessi, H., Barrat, G., Puisieux, F. and Devissaguet, J.-Ph., 1995a, Poly(D,L-lactide) nanocapsules containing non-steroidal anti-inflammatory drugs: gastrointestinal tolerance following intravenous and oral administration. Pharmaceutical Research 12, 1-3.
10. Guterres, S. S., Müller, C. R., Pohlmann, A. R. and Dalla Costa, T., 2001, Gastrointestinal tolerance following oral administration of spray-dried diclofenac-loaded nanocapsules and nanospheres. S.T.P. Pharma Sciences, 11, 229-233.
11. Huang, Y. C., Chiang, C. H. and Yeh, M. K., 2003, Optimizing formulation factors in preparing chitosan microparticles by spray-drying methods. Journal of Microencapsulation, 20, 247-260.
12. Kawashima, Y., Iwamoto, T., Niwa, T., Takeuchi, H. and Hino, T., 1993, Uniform and improved bioavailability of newly developed rapid and sustained release suspensions of ibuprofen microspheres. International Journal of Pharmaceutics, 89, 9-17.
13. Kibbe, A. H., 2000, Handbook of Pharmaceutical Excipients (London: Pharmaceutical Press).
14. Lin, S. and Kao, Y., 1991, Tablet formulation study of spray-dried sodium diclofenac enteric-coated microcapsules. Pharmaceutical Research, 8, 919-924.
15. Magenheim, B. and Benita, S., 1991, Nanoparticle characterization: a comprehensive physicochemical approach. S.T.P. Pharma Sciences, 1, 221-241.
16. Müller, C. R., Bassani, V. L., Pohlmann, A. R., Michalowski, C. B., Petrovick, P. R., and Guterres, S. S., 2000, Preparation and characterization of spray-dried polymeric nanocapsules. Drug Development and Industrial Pharmacy, 26, 343-347.
17. Müller, C. R., Schaffazick, S. R., Pohlmann, A. R., De Lucca Freitas, L., Pesce da Silveira, N., Dalla Costa, T., and Guterres, S. S., 2001, Spray-dried diclofenac-loaded poli(E-caprolactone) nanocapsules and nanospheres. preparation and physicochemical characterization. Pharmazie, 56, 864-867.
18. Palmieri, G. F., Bonacucina, G., Di Martino, P. and Martelli, S., 2001, Spray-drying as a method for microparticulate controlled release systems preparation: advantages and limits. I. Water-soluble drugs. Drug Development and Industrial Pharmacy, 27, 195-204.
19. Palmieri, G. F., Bonacucina, G., Di Martino, P. and Martelli, S., 2002, Gastroresistant microspheres containing ketoprofen, Journal of Microencapsulation, 19, 111-119.
20. Palmieri, G. F., Wehrle, P. and Stamm, A., 1994, Evaluation of spray-drying as a method to prepare microparticles for controlled drug release. Drug Development and Industrial Pharmacy, 20, 2859-2879.
21. Pohlmann, A. R., Weiss, V., Mertins, O., Pesce da Silveira, N. and Guterres, S. S., 2002, Spray-dried indomethacin-loaded polyester nanocapsules and nanospheres: development, stability evaluation and nanostructure models. European Journal of Pharmaceutical Sciences, 16, 305-312.
22. Skiba, M., Morva, C., Duchene, D., Puisieux, F. and Wouessidjewe, D., 1995, Evaluation of gastrointestinal behaviour in the rat of amphiphilic β-cyclodextrin nanocapsules, loaded with indomethacin. International Journal of Pharmaceutics, 126, 275-279.
23. Tuncay, M., Calis, S., Kas, H. S., Ercan, M. T., Peksoy, I. and Hincal, A. A., 2000, Diclofenac sodium incorporated plga (50:50) microspheres: formulation considerations and in vitro/in vivo evaluation. International Journal of Pharmaceutics, 195, 179-188.
24. Wan, L. S. C., Heng, P. W. S. and Chia, C. G. H., 1992, Spray drying as a process for microencapsulation and the effect of different coating polymers. Drug Development and Industrial Pharmacy, 18, 997-1011.
25. Watanabe, T. O., Wakiyama, N. O., Usui, F. O., Ikeda, M. O., Isobe, T. O. and Senna, M., 2001, Stability of amorphous indomethacin compounded with silica. International Journal of Pharmaceutics, 226, 81-91.