Organocatalytic asymmetric direct phosphonylation of α,β- unsaturated aldehydes: Mechanism, scope, and application in synthesis

Journal of Organic Chemistry

Volumn 72, Issue 23, 2007, Pages 8893-8903

  Maerten, Eddy ^a   Cabrera, Silvia ^a   Kjærsgaard, Anne ^a   Jørgensen, Karl Anker ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON ATOMS; PHOSPHONYLATION; RATE-DETERMINING STEPS;

ADDITION REACTIONS; ENANTIOSELECTIVITY; NUCLEOPHILES; STOICHIOMETRY; SYNTHESIS (CHEMICAL);

ALDEHYDES;

2 [BIS(3,5 BISTRIFLUOROMETHYLPHENYL)TRIMETHYLSILANOXYMETHYL]PYRROLIDINE; ALDEHYDE DERIVATIVE; ANTIMALARIAL AGENT; BENZOIC ACID; BRONSTED ACID; CARBON; GLUTAMIC ACID; HYDROXYL GROUP; PHOSPHITE; PHOSPHONIUM DERIVATIVE; PYRROLIDINE DERIVATIVE; SODIUM IODIDE; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC CATALYSIS; CATALYSIS; CENTRAL NERVOUS SYSTEM; CHEMICAL REACTION; DEALKYLATION; DENSITY FUNCTIONAL THEORY; ENANTIOSELECTIVITY; PHOSPHONYLATION; QUANTUM YIELD; REACTION ANALYSIS; SYNTHESIS;

ALDEHYDES; CATALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRYSTALLOGRAPHY, X-RAY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHITES; PHOSPHONIC ACIDS; STEREOISOMERISM;

EID: 35948976871     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo7018587     Document Type: Article

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