Early deregulation of the p16ink4a-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway in cell proliferation-driven esophageal tumorigenesis in zinc-deficient rats1

Cancer Research

Volumn 60, Issue 16, 2000, Pages 4589-4595

  Fong, L Y Y ^a   Nguyen, Vu T ^a   Farber, J L ^a   Huebner, K ^a   Magee, P N ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLINE; GENE PRODUCT; N BENZYL N METHYLNITROSAMINE; PROTEIN P16; RETINOBLASTOMA PROTEIN; CARCINOGEN; CARRIER PROTEIN; CDK4 PROTEIN, RAT; CYCLIN DEPENDENT KINASE 4; DIMETHYLNITROSAMINE; DRUG DERIVATIVE; ONCOPROTEIN; PROTEIN P16INK4A; ZINC;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL CYCLE; CELL GROWTH; CELL TRANSFORMATION; ESOPHAGUS CANCER; IMMUNOHISTOCHEMISTRY; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; RAT; ZINC DEFICIENCY; ANIMAL; BIOSYNTHESIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIVISION; COCARCINOGENESIS; CYTOLOGY; DRUG EFFECT; ESOPHAGUS; ESOPHAGUS TUMOR; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CARCINOGENS; CARRIER PROTEINS; CELL DIVISION; COCARCINOGENESIS; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; DIMETHYLNITROSAMINE; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; G1 PHASE; IMMUNOHISTOCHEMISTRY; MALE; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RETINOBLASTOMA PROTEIN; S PHASE; SIGNAL TRANSDUCTION; ZINC;

EID: 0034662498     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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