Confocal Raman microscopy can quantify advanced glycation end product (AGE) modifications in Bruch's membrane leading to accurate, nondestructive prediction of ocular aging

FASEB Journal

Volumn 21, Issue 13, 2007, Pages 3542-3552

  Glenn, Josephine V ^a   Beattie, J Renwick ^a   Barrett, Lindsay ^a   Frizzell, Norma ^b   Thorpe, Suzanne R ^b   Boulton, Mike E ^c   McGarvey, John J ^a   Stitt, Alan W ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Raman spectroscopy; RPE

Indexed keywords

ADVANCED GLYCATION END PRODUCT;

ACCURACY; ADULT; AGED; AGING; ANALYTIC METHOD; ARTICLE; AUTOPSY; BASEMENT MEMBRANE; BRUCH MEMBRANE; CELLULAR DISTRIBUTION; CHOROID; CONFOCAL MICROSCOPY; CONFOCAL RAMAN MICROSCOPY; DISEASE COURSE; DRUSEN; GAS CHROMATOGRAPHY; GENDER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN MODIFICATION; QUANTITATIVE ANALYSIS; RETINA MACULA AGE RELATED DEGENERATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TISSUE HOMOGENATE;

EID: 35948941926     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-7896com     Document Type: Article

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