The relationships of age changes in retinal pigment epithelium and Bruch's membrane

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 2, 1999, Pages 443-449

  Okubo, Akiko ^a   Rosa Jr , Robert H ^a   Bunce, Catey V ^a   Alexander, Robert A ^a   Fan, Joseph T ^a   Bird, Alan C ^a   Lutbert, Philip J ^a  

^a MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ARTICLE; AUTOFLUORESCENCE; BRUCH MEMBRANE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REGRESSION ANALYSIS; REPRODUCIBILITY; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA LUTEA; SECRETORY GRANULE; STATISTICAL MODEL; THICKNESS; TISSUE PREPARATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; BRUCH MEMBRANE; CHILD; CHILD, PRESCHOOL; FLUORESCENCE; HUMANS; INFANT; MELANOSOMES; MIDDLE AGED; PIGMENT EPITHELIUM OF EYE;

EID: 0032922283     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Evans J. Causes of blindness and partial sight in England and Wales. Studies on Medical and Population Subjects. No. 57 London: Her Majesty's Stationery Office; 1995;1990-1991.
2. Leibowitz HM, Krueger DE, Mauder LR, et al. The Framingham Eye Study monograph, 1973-75. Surv Ophthalmol 1988;24(Suppl): 335-610.
3. Gass JDM. Pathogenesis of disciform detachment on the neuroepithelium, Part 3, Senile disciform macular degeneration. Am J Ophthalmol. 1967;63:617-644.
4. Hogan MJ. Role of the retinal pigment epithelium in macular disease. Trans Am Acad Otolaryngol Ophthalmol. 1972;76:64-80.
5. Ishibashi T, Sorgente N, Patterson R, Ryan SJ. Pathogenesis of drusen in the primate. Invest Ophthalmol Vis Sci. 1986;27:184-193.
6. Rungger-Branche E, Englert U, Leuenberger PM. Exocytic clearing of degraded membrane material from pigment epithelial cells in frog retina. Invest Ophthalmol Vis Sci. 1988;28:2026-2037.
7. Ishibashi T, Patterson R, Oshnishi Y, Inomata H, Ryan RJ. Formation of drusen in the human eye. Am J Ophthalmol. 1986;101: 342-353.
8. Piguet B, Wells JA, Palmvang IB, Wormald R, Chisholm IH, Bird AC. Age-related Bruch's membrane change: a clinical study of the relative role of heredity and environment. Br J Ophthalmol. 1993; 77:400-403.
9. Heiba IM, Elston RC, Klein BEK, Klein R. Sibling correlations and segregation analysis of age-related maculopathy: The Beaver Dam eye study. Genet Epidemiol. 1994;11:51-67.
10. Silvestri TG, Johnson PB, Hughes. Is genetic predisposition an important risk factor in age-related macular disease? Eye. 1994;8: 564-568.
11. Klein ML, Mauldin WM, Stoumbos VD. Heredity and age-related macular degeneration: observations in monozygotic twins. Arch Ophthalmol. 1994;112:932-937.
12. Mares-Perlman JA, Brady WE, Klein R, et al. Serum oxidants and age-related macular degeneration in a population-based case-control study. Arch Ophthalmol. 1995;113:1518-1523.
13. Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids. Vitamins A, C, and E and advanced age related macular degeneration. JAMA. 1994;272:1413-1420.
14. Ott J. Complex traits on the map. Nature. 1996;379:772-773.
15. Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995;11:241-247.
16. Klein R, Klein BEK, Linton KLP. Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology. 1992;99: 933-943.
17. Mitchell P, Smith W, Attebo K, Wang JJ. Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study. Ophthalmology. 1995;102:1450-1460.
18. Vingerling JR, Dielemans I, Hofman A, et al. The prevalence of age-related maculopathy in the Rotterdam Study. Ophthalmology. 1995;102:205-210.
19. Wing GL, Blanchard GC, Weiter JJ. The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1976;17:601-607.
20. Feeney-Burns L, Hilderbrand ES, Eldridge S. Morphometric analysis of macular, equatorial and peripheral cells. Invest Ophthalmol Vis Sci. 1984;25:195-200.
21. Weiter JJ, Delori FC, Eing GL, Fitch KA. Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes. Invest Ophthalmol Vis Sci. 1986;27:145-152.
22. Feeney-Burns L, Burns RP, Gao C. Age-related changes in humans over 90 years old. Am J Ophthalmol. 1990;109:265-278.
23. Pauleikhoff D, Harper CA, Marshall J, et al. Aging changes in Bruch's membrane: a histological and morphologic study. Ophthalmology. 1990;97:171-178.
24. Sheraidah G, Steinmetz R, Maguire J, Pauleikhoff D, Marshall J, Bird AC. Correlation between lipids extracted from Bruch's membrane and age. Ophthalmology. 1993;110:47-51.
25. Holz FG, Sheraidah G, Pauleiklioff D, Bird AC. Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane. Arch Ophthalmol. 1994;112:402-406.
26. Ramrattan RS, van der Schaft TL, Mooy CM, de Bruijn WC, Mulder PGH, de Jong PTVM. Morphometric analysis of Bruch's membrane, the choriocapillaris and the choroid in aging. Invest Ophthalmol Vis Sci. 1994;35:2857-2864.
27. Delori FC, Dorey K, Staurenghi G, Arend O, Goger DG, Weiter JJ. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelial lipofuscin characteristics. Invest Ophthalmol Vis Sci. 1995;36:718-729.
28. von Ruckmann A, Fitzke FW, Bird AC. Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope. Invest Ophthalmol Vis Sci. 1997;38:478-486.
29. Eldred GE, Katz ML. Fluorophores of the human retinal pigment epithelium: separation and spectral characterization. Exp Eye Res. 1988;47:71-86.
30. Boulton M. Aging of the retinal pigment epithelium. Prog Retinal Res. 1991;11:125-152.
31. Yuodelis C, Hendrickson A. A qualitative and quantitative analysis of the human fovea during development. Vision Res. 1986;26: 847-855.
32. Keunen JEE, van Norren D, van Meel GL. Density of foveal cone pigment at older age. Invest Ophthalmol Vis Sci. 1987;28:985-991.
33. Curcio CA, Millican CL, Allen KA, Kalina RE. Aging of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina. Invest Ophthalmol Vis Sci. 1993;34:3278-3296.
34. Feeney L. Lipofuscin and melanin of human retinal pigment epithelium. Fluorescence enzyme cytochemical, and ultrastructural studies. Invest Ophthalmol Vis Sci. 1978;17:583-600.
35. Katz ML, Norberg M. Influence of dietary vitamin A on autofluorescence of leupeptin-induced inclusions in the retinal pigment epithelium. Exp Eye Res. 1992;54:239-246.
36. Docchio F, Boulton M, Cubeddu R, Ramponi R, Barker PD. Age-related changes in the fluorescence of melanin and lipofuscin granules of the retinal pigment epithelium: a time-resolved fluorescence spectroscopy study. Photochem Photobiol. 1991;54: 247-253.
37. Rozanowska M, Jarvis-Evans J, Korytowski W, Boulton ME, Burke JM, Sarna T. Blue light-induced reactivity of retinal age pigment. In vitro generation of oxygen-reactive species. J Biol Chem. 1995;27: 18825-18830.
38. Kubo N, Ohno Y, Yanagawa H, Yuzawa M, Matsui M, Uyama M. Research Committee on Chorioretinal Degenerations. Annual Estimated Number of Patients with Senile Disciform Macular Degeneration in Japan. Tokyo: The Ministry of Health and Welfare of Japan; 1989:136-139. (In Japanese).
39. Kubo N, Ohno Y, Yuzawa M, et al. Research committee on chorioretinal degenerations. Report on Nationwide Clinico-Epidemiological Survey of Senile Disciform Macular Degeneration in Japan. Tokyo: The Ministry of Health and Welfare of Japan; 1990: 121-124 (In Japanese).
40. Yuzawa M, Hagita K, Egawa T, Minato H, Matsui M. Macular lesions predisposing to senile disciform macular degeneration. Jpn J Ophthalmol. 1991;35:87-95.
41. Maruo T, Ikebukuro N, Kawanabe K, Kubota N. Changes in causes of visual handicaps in Tokyo. Jpn J Ophthalmol. 1991;35:268-272.
42. Yang CS, Lin CL, Lee FL, Tsai SC, Chung YM, Liu JH. Digital indocyanine green angiography in chorioretinal diseases. Chung Hua I Hsueh Tsa Chih Taipei. 1995;56:411-417.
43. Chen SN, Liu KR, Tsai CB, et al. Indocyanine green videoangiography of choroidal neovascular membrane in age-related macular degeneration. J Formos Med Assoc. 1993;92:823-828.