Non-invasive in vivo optical imaging of the lacZ and luc gene expression in mice

Gene Therapy

Volumn 14, Issue 22, 2007, Pages 1587-1593

  Josserand, V ^a,b,c   Texier Nogues, I ^d   Huber, P ^b,e   Favrot, M C ^a,b   Coll, J L ^a,b  

^a INSTITUT ALBERT BONNIOT   (France)

^b UNIV GRENOBLE ALPES   (France)

^c CERMEP IMAGERIE DU VIVANT   (France)

^d CEA LETI   (France)

^e CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; FIREFLY LUCIFERASE; PLASMID VECTOR; POLYETHYLENEIMINE; PYRANOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL GENE; BIOLUMINESCENCE; CELL KILLING; CONTROLLED STUDY; ENZYME ANALYSIS; FAR RED LIGHT; FEMALE; FLUORESCENCE ANALYSIS; FOLLOW UP; GENE EXPRESSION SYSTEM; GENETIC CODE; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; LUNG ALVEOLUS CELL; MOLECULAR IMAGING; MOUSE; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPORTER GENE; SENSITIVITY ANALYSIS; SKIN CELL; TRANSGENIC MOUSE; TUMOR CELL; TUMOR GROWTH;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS;

EID: 35848962532     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3303028     Document Type: Article

References (28)

1. Schenborn E, Groskreutz D. Reporter gene vectors and assays. Mol Biotechnol 1999; 13: 29-44.
2. Bogdanov AAJ, Weissleder R. In vivo imaging of gene delivery and expression. Trends Biotechnol 2002; 8: S11-S18.
3. Contag CH, Bachmann MH. Advances in in vivo bioluminescence imaging of gene expression. Annu Rev Biomed Eng 2002; 4: 235-260.
4. Liang Q, Nguyen K, Satyamurthy N, Barrio JR, Phelps ME, Gambhir SS et al. Monitoring adenoviral DNA delivery, using a mutant herpes simplex virus type 1 thymidine kinase gene as a PET reporter gene. Gene Therapy 2002; 9: 1659-1666.
5. Berger F, Gambhir SS. Recent advances in imaging endogenous or transferred gene expression utilizing radionuclide technologies in living subjects: Applications to breast cancer. Breast Cancer Res 2001; 3: 28-35.
6. Hoffman R. Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. Lancet Oncol 2002; 3: 546-556.
7. Weissleder R. Scaling down imaging: Molecular mapping of cancer in mice: Nat Rev Cancer 2002; 2: 11-18.
8. Sanes JR, Rubenstein JL, Nicolas JF. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J 1986; 5: 3133-3142.
9. James AL, Perry JD, Chilvers K, Robson IS, Armstrong L, Orr KE. Ahzarin-beta-D-galactoside: A new substrate for the detection of bacterial beta-galactosidase. Lett Appl Microbiol 2000; 30: 336-340.
10. Rakhmanova VA, MacDonald RC. A microplate fluorimetric assay for transfection of the beta-galactosidase reporter gene. Anal Biochem 1998; 257: 234-237.
11. Young DC, Kingsley SD, Ryan KA, Dutko FJ. Selective inactivation of eukaryotic beta-galactosidase in assays for inhibitors of HIV-1 TAT using bacterial beta-galactosidase as a reporter enzyme. Anal Biochem 1993; 215: 24-30.
12. Chilvers KF, Perry JD, James AL, Reed RH. Synthesis and evaluation of novel fluorogenic substrates for the detection of bacterial beta-galactosidase. J Appl microbiol 2001; 91: 1118-1130.
13. Gee KR, Sun WC, Bhalgat WK, Upson RH, Klaubert DH, Latham KA et al. Flurogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. Anal Biochem 1999; 273: 41-48.
14. Louie AY, Huber MM, Ahrens ET, Rothbächer U, Moats R, Jacobs RE et al. In vivo visualization of gene expression using magnetic resonance imaging. Nat Biotechnol 2000; 18: 321-325.
15. Lee KH, Byun SS, Choi JH, Paik JY, Choe YS, Kim BT. Targeting of lacZ reporter gene expression with radioiodine-labelled phenylethyl-beta-d-thiogalactopyranoside. Eur J Nucl Med Mol Imaging 2004; 31: 433-438.
16. Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout, D, Weissleder R. In vivo imaging of beta-galactosidase activity using far red fluorescent switch. Cancer Res 2004; 64: 1579-1583.
17. Weissleder R, Ntziachristos V. Shedding light onto live molecular targets. Nat Med 2003; 9, 123-128.
18. Brown EB, Campbell RB, Tsnzuki Y, Xu L, Carmeliet F, Fukumura D et al. In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multi-photon laser scanning microscopy. Nat Med 2001; 7: 864-868.
19. Corey PF, Trimmer RW, Biddlecom WG. A new chromogenic b-galactosidase substrates: 7-D-galactopyranosyloxy-9,9-dimethyl-9H-acridin- 2-one. Angew Chem Int Ed Engl 1991; 30: 1646-1648.
20. Chollet P, Favrot MC, Hurbin A, Coll JL. Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. J Gene Med 2002; 4: 84-91.
21. Prandini MH, Dreher I, Bouillot S, Benkerri S, Moll T, Huber P. The human VE-cadherin promoter is subjected to organ-specific regulation and is activated in tumour angiogenesis. Oncogene 2005; 24: 2992-3001.
22. Jenkins DE, Hornig YS, Oei Y, Dusich J, Purchio T. Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice. Breast Cancer Res 2005; 7: R444-R454.
23. Goula D, Benoist C, Mantero S, Merlo G, Levi G, Demeneix BA. Polyethylenimine-based intravenous delivery of transgenes to mouse lung. Gene Therapy 1998; 5: 1291-1295.
24. Coll JL, Chollet, P, Brambilla E, Desplanques D, Behr JP, Favrot M. In vivo delivery to tumors of DNA complexed with linear polyethylenimine. Hum Gene Ther 1999; 10: 1659-1666.
25. Zou SM, Erbacher P, Remy JS, Behr JP. Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse. J Gene Med 2000; 2 128-134.
26. Ntziachristos V, Tung CH, Bremer C, Weissleder R. Fluorescence molecular tomography resolves protease activity in vivo. Nat Med 2002; 8 757-760.
27. Garanger E, Boturyn D, Jin Z, Dumy P, Favrot MC, Coll JL. New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors. Mol Ther 2005; 12: 1168-1175.
28. Jin ZH, Josserand V, Razkin J, Garanger E, Boturyn D, Favrot MC et al. Noninvasive optical imaging of ovarian metastases using Cy5-labeled RAFT-c(-RGDfK-)4. Mol Imaging 2006; 5: 188-197.