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Volumn 6, Issue 10, 2007, Pages 2634-2641

Combined IFN-γ and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HISTONE H4; MAX PROTEIN; MYC PROTEIN; ORNITHINE DECARBOXYLASE; PROTEIN MAD1; RETINOIC ACID; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 35848937783     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0492     Document Type: Article
Times cited : (25)

References (49)
  • 1
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur GM. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 2003;3:203-16.
    • (2003) Nat Rev Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 2
    • 9644278104 scopus 로고    scopus 로고
    • MYCN amplification remains prognostically strong 20 years after its clinical debut
    • Cohn SL, Tweddle DA. MYCN amplification remains prognostically strong 20 years after its "clinical debut." Eur J Cancer 2004;40:2639-42.
    • (2004) Eur J Cancer , vol.40 , pp. 2639-2642
    • Cohn, S.L.1    Tweddle, D.A.2
  • 3
    • 0842309106 scopus 로고    scopus 로고
    • MYCN in neuronal tumours
    • Schwab M. MYCN in neuronal tumours. Cancer Lett 2004;204:179-87.
    • (2004) Cancer Lett , vol.204 , pp. 179-187
    • Schwab, M.1
  • 5
    • 0037189025 scopus 로고    scopus 로고
    • Regulation of N-myc expression in development and disease
    • Strieder V, Lutz W. Regulation of N-myc expression in development and disease. Cancer Lett 2002;180:107-19.
    • (2002) Cancer Lett , vol.180 , pp. 107-119
    • Strieder, V.1    Lutz, W.2
  • 8
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005;6:635-45.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 10
    • 0035904463 scopus 로고    scopus 로고
    • Function and regulation of the transcription factors of the Myc/Max/Mad network
    • Lüscher B. Function and regulation of the transcription factors of the Myc/Max/Mad network. Gene 2001;277:1-14.
    • (2001) Gene , vol.277 , pp. 1-14
    • Lüscher, B.1
  • 11
    • 0035500434 scopus 로고    scopus 로고
    • The interplay between Mad and Myc in proliferation and differentiation
    • Zhou ZQ, Hurlin PJ. The interplay between Mad and Myc in proliferation and differentiation. Trends Cell Biol 2001;11:S10-4.
    • (2001) Trends Cell Biol , vol.11
    • Zhou, Z.Q.1    Hurlin, P.J.2
  • 13
    • 0035881691 scopus 로고    scopus 로고
    • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
    • Bouchard C, Dittrich O, Kiermaier A, et al. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev 2001;15:2042-7.
    • (2001) Genes Dev , vol.15 , pp. 2042-2047
    • Bouchard, C.1    Dittrich, O.2    Kiermaier, A.3
  • 14
    • 0035957406 scopus 로고    scopus 로고
    • Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells
    • Xu D, Popov N, Hou M, et al. Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc Natl Acad Sci U S A 2001;98:3826-31.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 3826-3831
    • Xu, D.1    Popov, N.2    Hou, M.3
  • 15
    • 0038523952 scopus 로고    scopus 로고
    • Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network
    • Orian A, van Steensel B, Delrow J, et al. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev 2003;17:1101-14.
    • (2003) Genes Dev , vol.17 , pp. 1101-1114
    • Orian, A.1    van Steensel, B.2    Delrow, J.3
  • 17
    • 0036781812 scopus 로고    scopus 로고
    • c-MYC: More than just a matter of life and death
    • Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer 2002;2:764-76.
    • (2002) Nat Rev Cancer , vol.2 , pp. 764-776
    • Pelengaris, S.1    Khan, M.2    Evan, G.3
  • 18
    • 33947138135 scopus 로고    scopus 로고
    • Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation
    • Edsjo A, Holmquist L, Pahlman S. Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation. Semin Cancer Biol 2007;17:248-56.
    • (2007) Semin Cancer Biol , vol.17 , pp. 248-256
    • Edsjo, A.1    Holmquist, L.2    Pahlman, S.3
  • 19
    • 0033554684 scopus 로고    scopus 로고
    • Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrowtran splantation, and 13-cis-retinoic acid. Children's Cancer Group
    • Matthay KK, Villablanca JG, Seeger RC, et al. Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrowtran splantation, and 13-cis-retinoic acid. Children's Cancer Group. N Engl J Med 1999;341:1165-73.
    • (1999) N Engl J Med , vol.341 , pp. 1165-1173
    • Matthay, K.K.1    Villablanca, J.G.2    Seeger, R.C.3
  • 20
    • 0025728742 scopus 로고
    • Effects of interferon-γ and its interaction with retinoic acid on human neuroblastoma differentiation
    • Wuarin L, Verity MA, Sidell N. Effects of interferon-γ and its interaction with retinoic acid on human neuroblastoma differentiation. Int J Cancer 1991;48:136-41.
    • (1991) Int J Cancer , vol.48 , pp. 136-141
    • Wuarin, L.1    Verity, M.A.2    Sidell, N.3
  • 21
    • 0026610595 scopus 로고
    • γ-interferon and retinoic acid synergize in inhibiting the growth of human neuroblastoma cells in nude mice
    • Cornaglia-Ferraris P, Mariottini GL, Ponzoni M. γ-interferon and retinoic acid synergize in inhibiting the growth of human neuroblastoma cells in nude mice. Cancer Lett 1992;61:215-20.
    • (1992) Cancer Lett , vol.61 , pp. 215-220
    • Cornaglia-Ferraris, P.1    Mariottini, G.L.2    Ponzoni, M.3
  • 22
    • 0031455754 scopus 로고    scopus 로고
    • Interferon-γ and retinoic acid down-regulate N-myc in neuroblastoma through complementary mechanisms of action
    • Wada RK, Pai DS, Huang J, Yamashiro JM, Sidell N. Interferon-γ and retinoic acid down-regulate N-myc in neuroblastoma through complementary mechanisms of action. Cancer Lett 1997;121:181-8.
    • (1997) Cancer Lett , vol.121 , pp. 181-188
    • Wada, R.K.1    Pai, D.S.2    Huang, J.3    Yamashiro, J.M.4    Sidell, N.5
  • 23
    • 0035480012 scopus 로고    scopus 로고
    • Interferon-γ cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells
    • Guzhova I, Hultquist A, Cetinkaya C, Nilsson K, Pahlman S, Larsson LG. Interferon-γ cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells. Int J Cancer 2001;94:97-108.
    • (2001) Int J Cancer , vol.94 , pp. 97-108
    • Guzhova, I.1    Hultquist, A.2    Cetinkaya, C.3    Nilsson, K.4    Pahlman, S.5    Larsson, L.G.6
  • 24
    • 0020418633 scopus 로고
    • Effects of phorbol ester tumor promoters and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells
    • Spinelli W, Sonnenfeld KH, Ishii DN. Effects of phorbol ester tumor promoters and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells. Cancer Res 1982;42:5067-73.
    • (1982) Cancer Res , vol.42 , pp. 5067-5073
    • Spinelli, W.1    Sonnenfeld, K.H.2    Ishii, D.N.3
  • 25
    • 0033153098 scopus 로고    scopus 로고
    • Posttranslational regulation of Myc function in response to phorbol ester/interferon-γ-induced differentiation of v-Myc-transformed U- 937 monoblasts
    • Bahram F, Wu S, Öberg F, Lüscher B, Larsson LG. Posttranslational regulation of Myc function in response to phorbol ester/interferon-γ-induced differentiation of v-Myc-transformed U- 937 monoblasts. Blood 1999;93:3900-12.
    • (1999) Blood , vol.93 , pp. 3900-3912
    • Bahram, F.1    Wu, S.2    Öberg, F.3    Lüscher, B.4    Larsson, L.G.5
  • 26
    • 0029743372 scopus 로고    scopus 로고
    • Conditional expression of N-myc in human neuroblastoma cells increases expression of α-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
    • Lutz W, Stohr M, Schurmann J, Wenzel A, Lohr A, Schwab M. Conditional expression of N-myc in human neuroblastoma cells increases expression of α-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 1996;13:803-12.
    • (1996) Oncogene , vol.13 , pp. 803-812
    • Lutz, W.1    Stohr, M.2    Schurmann, J.3    Wenzel, A.4    Lohr, A.5    Schwab, M.6
  • 27
    • 0030024706 scopus 로고    scopus 로고
    • Overexpression of Mxi1 inhibits the induction of the human ornithine decarboxylase gene by the Myc/Max protein complex
    • Wu S, Pena A, Korcz A, Soprano DR, Soprano KJ. Overexpression of Mxi1 inhibits the induction of the human ornithine decarboxylase gene by the Myc/Max protein complex. Oncogene 1996;12:621-9.
    • (1996) Oncogene , vol.12 , pp. 621-629
    • Wu, S.1    Pena, A.2    Korcz, A.3    Soprano, D.R.4    Soprano, K.J.5
  • 28
    • 0033765517 scopus 로고    scopus 로고
    • Direct recruitment of N-myc to target gene promoters
    • Mac SM, D'Cunha CA, Farnham PJ. Direct recruitment of N-myc to target gene promoters. Mol Carcinog 2000;29:76-86.
    • (2000) Mol Carcinog , vol.29 , pp. 76-86
    • Mac, S.M.1    D'Cunha, C.A.2    Farnham, P.J.3
  • 29
    • 0343673898 scopus 로고    scopus 로고
    • Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1
    • Gunes C, Lichtsteiner S, Vasserot AP, Englert C. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res 2000;60:2116-21.
    • (2000) Cancer Res , vol.60 , pp. 2116-2121
    • Gunes, C.1    Lichtsteiner, S.2    Vasserot, A.P.3    Englert, C.4
  • 30
    • 0034624675 scopus 로고    scopus 로고
    • Identification of Mad as a repressor of the human telomerase (hTERT) gene
    • Oh S, Song YH, Yim J, Kim TK. Identification of Mad as a repressor of the human telomerase (hTERT) gene. Oncogene 2000;19:1485-90.
    • (2000) Oncogene , vol.19 , pp. 1485-1490
    • Oh, S.1    Song, Y.H.2    Yim, J.3    Kim, T.K.4
  • 31
    • 0035107916 scopus 로고    scopus 로고
    • Cytokine-induced restoration of differentiation and cell cycle arrest in v-Myc transformed U-937 monoblasts correlates with reduced Myc activity
    • Öberg F, Wu S, Bahram F, Nilsson K, Larsson LG. Cytokine-induced restoration of differentiation and cell cycle arrest in v-Myc transformed U-937 monoblasts correlates with reduced Myc activity. Leukemia 2001;15:217-27.
    • (2001) Leukemia , vol.15 , pp. 217-227
    • Öberg, F.1    Wu, S.2    Bahram, F.3    Nilsson, K.4    Larsson, L.G.5
  • 32
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21((WAF1/CIP1)) gene
    • Gartel AL, Tyner AL. Transcriptional regulation of the p21((WAF1/CIP1)) gene. Exp Cell Res 1999;246:280-9.
    • (1999) Exp Cell Res , vol.246 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 33
    • 0027987170 scopus 로고
    • Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53
    • Jiang H, Lin J, Su ZZ, Collart FR, Huberman E, Fisher PB. Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene 1994;9:3397-406.
    • (1994) Oncogene , vol.9 , pp. 3397-3406
    • Jiang, H.1    Lin, J.2    Su, Z.Z.3    Collart, F.R.4    Huberman, E.5    Fisher, P.B.6
  • 34
    • 0027945476 scopus 로고    scopus 로고
    • Steinman RA, Hoffman B, IroA, Guillouf C, Liebermann DA, el-Houseini ME. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene 1994;9:3389-96.
    • Steinman RA, Hoffman B, IroA, Guillouf C, Liebermann DA, el-Houseini ME. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene 1994;9:3389-96.
  • 35
    • 0034610545 scopus 로고    scopus 로고
    • p27Kip1 accumulation is associated with retinoic-induced neuroblastoma differentiation: Evidence of a decreased proteasome-dependent degradation
    • Borriello A, Pietra VD, Criscuolo M, et al. p27Kip1 accumulation is associated with retinoic-induced neuroblastoma differentiation: evidence of a decreased proteasome-dependent degradation. Oncogene 2000;19:51-60.
    • (2000) Oncogene , vol.19 , pp. 51-60
    • Borriello, A.1    Pietra, V.D.2    Criscuolo, M.3
  • 36
    • 0038026135 scopus 로고    scopus 로고
    • Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2
    • Nakamura M, Matsuo T, Stauffer J, Neckers L, Thiele CJ. Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2. Cell Death Differ 2003;10:230-9.
    • (2003) Cell Death Differ , vol.10 , pp. 230-239
    • Nakamura, M.1    Matsuo, T.2    Stauffer, J.3    Neckers, L.4    Thiele, C.J.5
  • 37
    • 0036232595 scopus 로고    scopus 로고
    • MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity
    • McArthur GA, Foley KP, Fero ML, et al. MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity. Mol Cell Biol 2002;22:3014-23.
    • (2002) Mol Cell Biol , vol.22 , pp. 3014-3023
    • McArthur, G.A.1    Foley, K.P.2    Fero, M.L.3
  • 38
    • 13944282126 scopus 로고    scopus 로고
    • Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells
    • Walkley CR, Fero ML, Chien WM, Purton LE, McArthur GA. Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells. Nat Cell Biol 2005;7:172-8.
    • (2005) Nat Cell Biol , vol.7 , pp. 172-178
    • Walkley, C.R.1    Fero, M.L.2    Chien, W.M.3    Purton, L.E.4    McArthur, G.A.5
  • 39
    • 0842325799 scopus 로고    scopus 로고
    • Restoration of promyelocytic leukemia protein-nuclear bodies in neuroblastoma cells enhances retinoic acid responsiveness
    • Yu JH, Nakajima A, Nakajima H, Diller LR, Bloch KD, Bloch DB. Restoration of promyelocytic leukemia protein-nuclear bodies in neuroblastoma cells enhances retinoic acid responsiveness. Cancer Res 2004;64:928-33.
    • (2004) Cancer Res , vol.64 , pp. 928-933
    • Yu, J.H.1    Nakajima, A.2    Nakajima, H.3    Diller, L.R.4    Bloch, K.D.5    Bloch, D.B.6
  • 40
    • 0034968656 scopus 로고    scopus 로고
    • Role of PML and PML-RARa in Mad-mediated transcriptional repression
    • Khan MM, Nomura T, Kim H, et al. Role of PML and PML-RARa in Mad-mediated transcriptional repression. Mol Cell 2001;7:1233-43.
    • (2001) Mol Cell , vol.7 , pp. 1233-1243
    • Khan, M.M.1    Nomura, T.2    Kim, H.3
  • 41
    • 21644467027 scopus 로고    scopus 로고
    • c-Myc localization within the nucleus: Evidence for association with the PML nuclear body
    • Smith KP, Byron M, O'Connell BC, et al. c-Myc localization within the nucleus: evidence for association with the PML nuclear body. J Cell Biochem 2004;93:1282-96.
    • (2004) J Cell Biochem , vol.93 , pp. 1282-1296
    • Smith, K.P.1    Byron, M.2    O'Connell, B.C.3
  • 42
    • 16444380896 scopus 로고    scopus 로고
    • PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts
    • Cairo S, De Falco F, Pizzo M, Salomoni P, Pandolfi PP, Meroni G. PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts. Oncogene 2005;24:2195-203.
    • (2005) Oncogene , vol.24 , pp. 2195-2203
    • Cairo, S.1    De Falco, F.2    Pizzo, M.3    Salomoni, P.4    Pandolfi, P.P.5    Meroni, G.6
  • 43
    • 0029997640 scopus 로고    scopus 로고
    • Differentiation therapy of acute promyelocytic leukemia: Clinical and molecular features [see comments]
    • Miller W, Jr. Differentiation therapy of acute promyelocytic leukemia: clinical and molecular features [see comments]. Cancer Invest 1996;14:142-50.
    • (1996) Cancer Invest , vol.14 , pp. 142-150
    • Miller Jr., W.1
  • 45
    • 0024427470 scopus 로고
    • The effects of γ interferon on the natural killer and tumor cells of children with neuroblastoma. A preliminary report
    • Evans A, Main E, Zier K, et al. The effects of γ interferon on the natural killer and tumor cells of children with neuroblastoma. A preliminary report. Cancer 1989;64:1383-7.
    • (1989) Cancer , vol.64 , pp. 1383-1387
    • Evans, A.1    Main, E.2    Zier, K.3
  • 46
    • 0032560653 scopus 로고    scopus 로고
    • MycN and IFNγ cooperate in apoptosis of human neuroblastoma cells
    • Lutz W, Fulda S, Jeremias I, Debatin KM, Schwab M. MycN and IFNγ cooperate in apoptosis of human neuroblastoma cells. Oncogene 1998;17:339-46.
    • (1998) Oncogene , vol.17 , pp. 339-346
    • Lutz, W.1    Fulda, S.2    Jeremias, I.3    Debatin, K.M.4    Schwab, M.5
  • 47
    • 0032588320 scopus 로고    scopus 로고
    • Induction of apoptosis by IFNγ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit
    • Bernassola F, Scheuerpflug C, Herr I, Krammer PH, Debatin KM, Melino G. Induction of apoptosis by IFNγ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit. Cell Death Differ 1999;6:652-60.
    • (1999) Cell Death Differ , vol.6 , pp. 652-660
    • Bernassola, F.1    Scheuerpflug, C.2    Herr, I.3    Krammer, P.H.4    Debatin, K.M.5    Melino, G.6
  • 48
    • 84889271499 scopus 로고    scopus 로고
    • IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
    • Fulda S, Debatin KM. IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene 2002;21:2295-308.
    • (2002) Oncogene , vol.21 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.M.2
  • 49
    • 0037373901 scopus 로고    scopus 로고
    • Induction of caspase 8 by interferon γ renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB
    • Yang X, Merchant MS, Romero ME, et al. Induction of caspase 8 by interferon γ renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Cancer Res 2003;63:1122-9.
    • (2003) Cancer Res , vol.63 , pp. 1122-1129
    • Yang, X.1    Merchant, M.S.2    Romero, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.