-
2
-
-
0030746359
-
The development of a model for the homing of multiple myeloma cells to human bone marrow
-
Urashima M., Chen B.P., Chen S., et al. The development of a model for the homing of multiple myeloma cells to human bone marrow. Blood 90 2 (1997) 754-765
-
(1997)
Blood
, vol.90
, Issue.2
, pp. 754-765
-
-
Urashima, M.1
Chen, B.P.2
Chen, S.3
-
3
-
-
0032930729
-
Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice
-
Hjorth-Hansen H., Seifert M.F., Borset M., et al. Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice. J Bone Miner Res 14 2 (1999) 256-263
-
(1999)
J Bone Miner Res
, vol.14
, Issue.2
, pp. 256-263
-
-
Hjorth-Hansen, H.1
Seifert, M.F.2
Borset, M.3
-
4
-
-
0142188727
-
Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications
-
Mitsiades C.S., Mitsiades N.S., Bronson R.T., et al. Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications. Cancer Res 63 20 (2003) 6689-6696
-
(2003)
Cancer Res
, vol.63
, Issue.20
, pp. 6689-6696
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
Bronson, R.T.3
-
5
-
-
0018351394
-
Idiopathic paraproteinemia. II. Transplantation of the paraprotein-producing clone from old to young C57BL/KaLwRij mice
-
Radl J., De Glopper E.D., Schuit H.R., et al. Idiopathic paraproteinemia. II. Transplantation of the paraprotein-producing clone from old to young C57BL/KaLwRij mice. J Immunol 122 2 (1979) 609-613
-
(1979)
J Immunol
, vol.122
, Issue.2
, pp. 609-613
-
-
Radl, J.1
De Glopper, E.D.2
Schuit, H.R.3
-
6
-
-
0027279967
-
Heterotransplantation of human multiple myeloma cell lines in severe combined immunodeficiency (SCID) mice
-
Tong A.W., Huang Y.W., Zhang B.Q., et al. Heterotransplantation of human multiple myeloma cell lines in severe combined immunodeficiency (SCID) mice. Anticancer Res 13 3 (1993) 593-597
-
(1993)
Anticancer Res
, vol.13
, Issue.3
, pp. 593-597
-
-
Tong, A.W.1
Huang, Y.W.2
Zhang, B.Q.3
-
7
-
-
0036735298
-
Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model
-
LeBlanc R., Catley L.P., Hideshima T., et al. Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model. Cancer Res 62 17 (2002) 4996-5000
-
(2002)
Cancer Res
, vol.62
, Issue.17
, pp. 4996-5000
-
-
LeBlanc, R.1
Catley, L.P.2
Hideshima, T.3
-
8
-
-
33750209537
-
A novel proteasome inhibitor NPI-0052 as an anticancer therapy
-
Chauhan D., Hideshima T., and Anderson K.C. A novel proteasome inhibitor NPI-0052 as an anticancer therapy. Br J Cancer 95 8 (2006) 961-965
-
(2006)
Br J Cancer
, vol.95
, Issue.8
, pp. 961-965
-
-
Chauhan, D.1
Hideshima, T.2
Anderson, K.C.3
-
9
-
-
0037089554
-
S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice
-
Lentzsch S., Rogers M.S., LeBlanc R., et al. S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice. Cancer Res 62 8 (2002) 2300-2305
-
(2002)
Cancer Res
, vol.62
, Issue.8
, pp. 2300-2305
-
-
Lentzsch, S.1
Rogers, M.S.2
LeBlanc, R.3
-
10
-
-
33751258297
-
Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90
-
Sydor J.R., Normant E., Pien C.S., et al. Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90. Proc Natl Acad Sci U S A 103 46 (2006) 17408-17413
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.46
, pp. 17408-17413
-
-
Sydor, J.R.1
Normant, E.2
Pien, C.S.3
-
11
-
-
33646577479
-
Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells
-
Hideshima T., Catley L., Yasui H., et al. Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells. Blood 107 10 (2006) 4053-4062
-
(2006)
Blood
, vol.107
, Issue.10
, pp. 4053-4062
-
-
Hideshima, T.1
Catley, L.2
Yasui, H.3
-
12
-
-
33646555792
-
The inhibitory anti-FGFR3 antibody, PRO-001, is cytotoxic to t(4;14) multiple myeloma cells
-
Trudel S., Stewart A.K., Rom E., et al. The inhibitory anti-FGFR3 antibody, PRO-001, is cytotoxic to t(4;14) multiple myeloma cells. Blood 107 10 (2006) 4039-4046
-
(2006)
Blood
, vol.107
, Issue.10
, pp. 4039-4046
-
-
Trudel, S.1
Stewart, A.K.2
Rom, E.3
-
13
-
-
1942456800
-
Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma
-
Trudel S., Ely S., Farooqi Y., et al. Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma. Blood 103 9 (2004) 3521-3528
-
(2004)
Blood
, vol.103
, Issue.9
, pp. 3521-3528
-
-
Trudel, S.1
Ely, S.2
Farooqi, Y.3
-
14
-
-
15944378835
-
CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma
-
Trudel S., Li Z.H., Wei E., et al. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma. Blood 105 7 (2005) 2941-2948
-
(2005)
Blood
, vol.105
, Issue.7
, pp. 2941-2948
-
-
Trudel, S.1
Li, Z.H.2
Wei, E.3
-
15
-
-
0035437171
-
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications
-
Mitsiades C.S., Treon S.P., Mitsiades N., et al. TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications. Blood 98 3 (2001) 795-804
-
(2001)
Blood
, vol.98
, Issue.3
, pp. 795-804
-
-
Mitsiades, C.S.1
Treon, S.P.2
Mitsiades, N.3
-
16
-
-
33846884216
-
The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan
-
Trudel S., Stewart A.K., Li Z., et al. The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan. Clin Cancer Res 13 2 Pt 1 (2007) 621-629
-
(2007)
Clin Cancer Res
, vol.13
, Issue.2 PART 1
, pp. 621-629
-
-
Trudel, S.1
Stewart, A.K.2
Li, Z.3
-
17
-
-
33845882259
-
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma
-
Podar K., Tonon G., Sattler M., et al. The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma. Proc Natl Acad Sci U S A 103 51 (2006) 19478-19483
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.51
, pp. 19478-19483
-
-
Podar, K.1
Tonon, G.2
Sattler, M.3
-
18
-
-
33744494283
-
Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo
-
Navas T.A., Nguyen A.N., Hideshima T., et al. Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo. Leukemia 20 6 (2006) 1017-1027
-
(2006)
Leukemia
, vol.20
, Issue.6
, pp. 1017-1027
-
-
Navas, T.A.1
Nguyen, A.N.2
Hideshima, T.3
-
19
-
-
19944428071
-
Patupilone (epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo
-
Lin B., Catley L., LeBlanc R., et al. Patupilone (epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo. Blood 105 1 (2005) 350-357
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 350-357
-
-
Lin, B.1
Catley, L.2
LeBlanc, R.3
-
20
-
-
33644516582
-
Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis
-
Yan H., Frost P., Shi Y., et al. Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis. Cancer Res 66 4 (2006) 2305-2313
-
(2006)
Cancer Res
, vol.66
, Issue.4
, pp. 2305-2313
-
-
Yan, H.1
Frost, P.2
Shi, Y.3
-
21
-
-
0026724269
-
Anti-human interleukin-6 receptor antibody inhibits human myeloma growth in vivo
-
Suzuki H., Yasukawa K., Saito T., et al. Anti-human interleukin-6 receptor antibody inhibits human myeloma growth in vivo. Eur J Immunol 22 8 (1992) 1989-1993
-
(1992)
Eur J Immunol
, vol.22
, Issue.8
, pp. 1989-1993
-
-
Suzuki, H.1
Yasukawa, K.2
Saito, T.3
-
22
-
-
0032103451
-
Radioimmunodetection of human myeloma xenografts with a monoclonal antibody directed against a plasma cell specific antigen, HM1.24
-
Ozaki S., Kosaka M., Harada M., et al. Radioimmunodetection of human myeloma xenografts with a monoclonal antibody directed against a plasma cell specific antigen, HM1.24. Cancer 82 11 (1998) 2184-2190
-
(1998)
Cancer
, vol.82
, Issue.11
, pp. 2184-2190
-
-
Ozaki, S.1
Kosaka, M.2
Harada, M.3
-
23
-
-
3242777803
-
Advances in biology of multiple myeloma: clinical applications
-
Hideshima T., Bergsagel P.L., Kuehl W.M., et al. Advances in biology of multiple myeloma: clinical applications. Blood 104 3 (2004) 607-618
-
(2004)
Blood
, vol.104
, Issue.3
, pp. 607-618
-
-
Hideshima, T.1
Bergsagel, P.L.2
Kuehl, W.M.3
-
24
-
-
0024213523
-
Infection of the SCID-hu mouse by HIV-1
-
Namikawa R., Kaneshima H., Lieberman M., et al. Infection of the SCID-hu mouse by HIV-1. Science 242 4886 (1988) 1684-1686
-
(1988)
Science
, vol.242
, Issue.4886
, pp. 1684-1686
-
-
Namikawa, R.1
Kaneshima, H.2
Lieberman, M.3
-
25
-
-
0023753744
-
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function
-
McCune J.M., Namikawa R., Kaneshima H., et al. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 241 4873 (1988) 1632-1639
-
(1988)
Science
, vol.241
, Issue.4873
, pp. 1632-1639
-
-
McCune, J.M.1
Namikawa, R.2
Kaneshima, H.3
-
26
-
-
0032532608
-
Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations
-
Yaccoby S., Barlogie B., and Epstein J. Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations. Blood 92 8 (1998) 2908-2913
-
(1998)
Blood
, vol.92
, Issue.8
, pp. 2908-2913
-
-
Yaccoby, S.1
Barlogie, B.2
Epstein, J.3
-
27
-
-
22844450849
-
The SCID-hu myeloma model
-
Epstein J., and Yaccoby S. The SCID-hu myeloma model. Methods Mol Med 113 (2005) 183-190
-
(2005)
Methods Mol Med
, vol.113
, pp. 183-190
-
-
Epstein, J.1
Yaccoby, S.2
-
28
-
-
0033570946
-
The proliferative potential of myeloma plasma cells manifest in the SCID-hu host
-
Yaccoby S., and Epstein J. The proliferative potential of myeloma plasma cells manifest in the SCID-hu host. Blood 94 10 (1999) 3576-3582
-
(1999)
Blood
, vol.94
, Issue.10
, pp. 3576-3582
-
-
Yaccoby, S.1
Epstein, J.2
-
29
-
-
0036891888
-
Antimyeloma efficacy of thalidomide in the SCID-hu model
-
Yaccoby S., Johnson C.L., Mahaffey S.C., et al. Antimyeloma efficacy of thalidomide in the SCID-hu model. Blood 100 12 (2002) 4162-4168
-
(2002)
Blood
, vol.100
, Issue.12
, pp. 4162-4168
-
-
Yaccoby, S.1
Johnson, C.L.2
Mahaffey, S.C.3
-
30
-
-
0035949510
-
Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
-
Pearse R.N., Sordillo E.M., Yaccoby S., et al. Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A 98 20 (2001) 11581-11586
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.20
, pp. 11581-11586
-
-
Pearse, R.N.1
Sordillo, E.M.2
Yaccoby, S.3
-
31
-
-
0036181668
-
Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
-
Yaccoby S., Pearse R.N., Johnson C.L., et al. Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. Br J Haematol 116 2 (2002) 278-290
-
(2002)
Br J Haematol
, vol.116
, Issue.2
, pp. 278-290
-
-
Yaccoby, S.1
Pearse, R.N.2
Johnson, C.L.3
-
32
-
-
0037303260
-
RANK-Fc: a therapeutic antagonist for RANK-L in myeloma
-
Sordillo E.M., and Pearse R.N. RANK-Fc: a therapeutic antagonist for RANK-L in myeloma. Cancer 97 3 Suppl (2003) 802-812
-
(2003)
Cancer
, vol.97
, Issue.3 SUPPL
, pp. 802-812
-
-
Sordillo, E.M.1
Pearse, R.N.2
-
33
-
-
33750283069
-
MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo
-
Hideshima T., Neri P., Tassone P., et al. MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo. Clin Cancer Res 12 19 (2006) 5887-5894
-
(2006)
Clin Cancer Res
, vol.12
, Issue.19
, pp. 5887-5894
-
-
Hideshima, T.1
Neri, P.2
Tassone, P.3
-
34
-
-
20444416005
-
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells
-
Zhu K., Gerbino E., Beaupre D.M., et al. Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells. Blood 105 12 (2005) 4759-4766
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4759-4766
-
-
Zhu, K.1
Gerbino, E.2
Beaupre, D.M.3
-
35
-
-
9444223279
-
Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells
-
Tassone P., Goldmacher V.S., Neri P., et al. Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells. Blood 104 12 (2004) 3688-3696
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3688-3696
-
-
Tassone, P.1
Goldmacher, V.S.2
Neri, P.3
-
36
-
-
33646408780
-
Inhibition of bone-derived insulin-like growth factors by a ligand-specific antibody suppresses the growth of human multiple myeloma in the human adult bone explanted in NOD/SCID mouse
-
Araki K., Sangai T., Miyamoto S., et al. Inhibition of bone-derived insulin-like growth factors by a ligand-specific antibody suppresses the growth of human multiple myeloma in the human adult bone explanted in NOD/SCID mouse. Int J Cancer 118 10 (2006) 2602-2608
-
(2006)
Int J Cancer
, vol.118
, Issue.10
, pp. 2602-2608
-
-
Araki, K.1
Sangai, T.2
Miyamoto, S.3
-
37
-
-
20344385768
-
Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu In vivo model of human multiple myeloma
-
Tassone P., Neri P., Burger R., et al. Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu In vivo model of human multiple myeloma. Clin Cancer Res 11 11 (2005) 4251-4258
-
(2005)
Clin Cancer Res
, vol.11
, Issue.11
, pp. 4251-4258
-
-
Tassone, P.1
Neri, P.2
Burger, R.3
-
38
-
-
3042822264
-
In vitro and in vivo activity of the maytansinoid immunoconjugate huN901-N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-maytansine against CD56+ multiple myeloma cells
-
Tassone P., Gozzini A., Goldmacher V., et al. In vitro and in vivo activity of the maytansinoid immunoconjugate huN901-N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-maytansine against CD56+ multiple myeloma cells. Cancer Res 64 13 (2004) 4629-4636
-
(2004)
Cancer Res
, vol.64
, Issue.13
, pp. 4629-4636
-
-
Tassone, P.1
Gozzini, A.2
Goldmacher, V.3
-
39
-
-
8844264524
-
The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells
-
Yata K., and Yaccoby S. The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells. Leukemia 18 11 (2004) 1891-1897
-
(2004)
Leukemia
, vol.18
, Issue.11
, pp. 1891-1897
-
-
Yata, K.1
Yaccoby, S.2
-
40
-
-
0034142369
-
Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice
-
Pilarski L.M., Hipperson G., Seeberger K., et al. Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice. Blood 95 3 (2000) 1056-1065
-
(2000)
Blood
, vol.95
, Issue.3
, pp. 1056-1065
-
-
Pilarski, L.M.1
Hipperson, G.2
Seeberger, K.3
-
41
-
-
0036191321
-
Leukemic B cells clonally identical to myeloma plasma cells are myelomagenic in NOD/SCID mice
-
Pilarski L.M., Seeberger K., Coupland R.W., et al. Leukemic B cells clonally identical to myeloma plasma cells are myelomagenic in NOD/SCID mice. Exp Hematol 30 3 (2002) 221-228
-
(2002)
Exp Hematol
, vol.30
, Issue.3
, pp. 221-228
-
-
Pilarski, L.M.1
Seeberger, K.2
Coupland, R.W.3
-
42
-
-
0030821607
-
New xenograft model of multiple myeloma and efficacy of a humanized antibody against human interleukin-6 receptor
-
Tsunenari T., Koishihara Y., Nakamura A., et al. New xenograft model of multiple myeloma and efficacy of a humanized antibody against human interleukin-6 receptor. Blood 90 6 (1997) 2437-2444
-
(1997)
Blood
, vol.90
, Issue.6
, pp. 2437-2444
-
-
Tsunenari, T.1
Koishihara, Y.2
Nakamura, A.3
-
43
-
-
10744225890
-
Establishment of a new model of human multiple myeloma using NOD/SCID/gammac(null) (NOG) mice
-
Miyakawa Y., Ohnishi Y., Tomisawa M., et al. Establishment of a new model of human multiple myeloma using NOD/SCID/gammac(null) (NOG) mice. Biochem Biophys Res Commun 313 2 (2004) 258-262
-
(2004)
Biochem Biophys Res Commun
, vol.313
, Issue.2
, pp. 258-262
-
-
Miyakawa, Y.1
Ohnishi, Y.2
Tomisawa, M.3
-
44
-
-
12144290914
-
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
-
Mitsiades C.S., Mitsiades N.S., McMullan C.J., et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell 5 3 (2004) 221-230
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 221-230
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
45
-
-
4143149779
-
Prompt tumor formation and maintenance of constitutive NF-kappaB activity of multiple myeloma cells in NOD/SCID/gammacnull mice
-
Dewan M.Z., Watanabe M., Terashima K., et al. Prompt tumor formation and maintenance of constitutive NF-kappaB activity of multiple myeloma cells in NOD/SCID/gammacnull mice. Cancer Sci 95 7 (2004) 564-568
-
(2004)
Cancer Sci
, vol.95
, Issue.7
, pp. 564-568
-
-
Dewan, M.Z.1
Watanabe, M.2
Terashima, K.3
-
46
-
-
23044482259
-
Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo
-
Wu K.D., Cho Y.S., Katz J., et al. Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo. Proc Natl Acad Sci U S A 102 30 (2005) 10640-10645
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.30
, pp. 10640-10645
-
-
Wu, K.D.1
Cho, Y.S.2
Katz, J.3
-
47
-
-
31544436323
-
Antimyeloma activity of heat shock protein-90 inhibition
-
Mitsiades C.S., Mitsiades N.S., McMullan C.J., et al. Antimyeloma activity of heat shock protein-90 inhibition. Blood 107 3 (2006) 1092-1100
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 1092-1100
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
48
-
-
33748349241
-
CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice
-
Xin X., Abrams T.J., Hollenbach P.W., et al. CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice. Clin Cancer Res 12 16 (2006) 4908-4915
-
(2006)
Clin Cancer Res
, vol.12
, Issue.16
, pp. 4908-4915
-
-
Xin, X.1
Abrams, T.J.2
Hollenbach, P.W.3
-
49
-
-
33745949229
-
CD52 antigen expressed by malignant plasma cells can be targeted by alemtuzumab in vivo in NOD/SCID mice
-
Carlo-Stella C., Guidetti A., Di Nicola M., et al. CD52 antigen expressed by malignant plasma cells can be targeted by alemtuzumab in vivo in NOD/SCID mice. Exp Hematol 34 6 (2006) 721-727
-
(2006)
Exp Hematol
, vol.34
, Issue.6
, pp. 721-727
-
-
Carlo-Stella, C.1
Guidetti, A.2
Di Nicola, M.3
-
50
-
-
33747872306
-
A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6
-
Baughn L.B., Di Liberto M., Wu K., et al. A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6. Cancer Res 66 15 (2006) 7661-7667
-
(2006)
Cancer Res
, vol.66
, Issue.15
, pp. 7661-7667
-
-
Baughn, L.B.1
Di Liberto, M.2
Wu, K.3
-
51
-
-
33845959800
-
Antibody targeting of the insulin-like growth factor I receptor enhances the anti-tumor response of multiple myeloma to chemotherapy through inhibition of tumor proliferation and angiogenesis
-
Wu K.D., Zhou L., Burtrum D., et al. Antibody targeting of the insulin-like growth factor I receptor enhances the anti-tumor response of multiple myeloma to chemotherapy through inhibition of tumor proliferation and angiogenesis. Cancer Immunol Immunother 56 3 (2007) 343-357
-
(2007)
Cancer Immunol Immunother
, vol.56
, Issue.3
, pp. 343-357
-
-
Wu, K.D.1
Zhou, L.2
Burtrum, D.3
-
52
-
-
0027534880
-
Disseminated growth of a human multiple myeloma cell line in mice with severe combined immunodeficiency disease
-
Huang Y.W., Richardson J.A., Tong A.W., et al. Disseminated growth of a human multiple myeloma cell line in mice with severe combined immunodeficiency disease. Cancer Res 53 6 (1993) 1392-1396
-
(1993)
Cancer Res
, vol.53
, Issue.6
, pp. 1392-1396
-
-
Huang, Y.W.1
Richardson, J.A.2
Tong, A.W.3
-
53
-
-
0029129937
-
An in vivo model of human multiple myeloma bone disease
-
Alsina M., Boyce B.F., Mundy G.R., et al. An in vivo model of human multiple myeloma bone disease. Stem Cells 13 Suppl 2 (1995) 48-50
-
(1995)
Stem Cells
, vol.13
, Issue.SUPPL. 2
, pp. 48-50
-
-
Alsina, M.1
Boyce, B.F.2
Mundy, G.R.3
-
54
-
-
0030019981
-
Development of an in vivo model of human multiple myeloma bone disease
-
Alsina M., Boyce B., Devlin R.D., et al. Development of an in vivo model of human multiple myeloma bone disease. Blood 87 4 (1996) 1495-1501
-
(1996)
Blood
, vol.87
, Issue.4
, pp. 1495-1501
-
-
Alsina, M.1
Boyce, B.2
Devlin, R.D.3
-
55
-
-
0030069665
-
Development of an orthotopic SCID mouse-human tumor xenograft model displaying the multidrug-resistant phenotype
-
Bellamy W.T., Mendibles P., Bontje P., et al. Development of an orthotopic SCID mouse-human tumor xenograft model displaying the multidrug-resistant phenotype. Cancer Chemother Pharmacol 37 4 (1996) 305-316
-
(1996)
Cancer Chemother Pharmacol
, vol.37
, Issue.4
, pp. 305-316
-
-
Bellamy, W.T.1
Mendibles, P.2
Bontje, P.3
-
56
-
-
2142709468
-
Persistent use of false myeloma cell lines
-
Drexler H.G., Matsuo Y., and MacLeod R.A. Persistent use of false myeloma cell lines. Hum Cell 16 3 (2003) 101-105
-
(2003)
Hum Cell
, vol.16
, Issue.3
, pp. 101-105
-
-
Drexler, H.G.1
Matsuo, Y.2
MacLeod, R.A.3
-
57
-
-
0036794974
-
Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors
-
Pilarski L.M., and Belch A.R. Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors. Clin Cancer Res 8 10 (2002) 3198-3204
-
(2002)
Clin Cancer Res
, vol.8
, Issue.10
, pp. 3198-3204
-
-
Pilarski, L.M.1
Belch, A.R.2
-
58
-
-
0036512435
-
Multiple myeloma: evolving genetic events and host interactions
-
Kuehl W.M., and Bergsagel P.L. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer 2 3 (2002) 175-187
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.3
, pp. 175-187
-
-
Kuehl, W.M.1
Bergsagel, P.L.2
-
59
-
-
20344381988
-
A clinically relevant SCID-hu in vivo model of human multiple myeloma
-
Tassone P., Neri P., Carrasco D.R., et al. A clinically relevant SCID-hu in vivo model of human multiple myeloma. Blood 106 2 (2005) 713-716
-
(2005)
Blood
, vol.106
, Issue.2
, pp. 713-716
-
-
Tassone, P.1
Neri, P.2
Carrasco, D.R.3
-
60
-
-
7944231931
-
Visualization of 5T33 myeloma cells in the C57BL/KaLwRij mouse: establishment of a new syngeneic murine model of multiple myeloma
-
Alici E., Konstantinidis K.V., Aints A., et al. Visualization of 5T33 myeloma cells in the C57BL/KaLwRij mouse: establishment of a new syngeneic murine model of multiple myeloma. Exp Hematol 32 11 (2004) 1064-1072
-
(2004)
Exp Hematol
, vol.32
, Issue.11
, pp. 1064-1072
-
-
Alici, E.1
Konstantinidis, K.V.2
Aints, A.3
-
61
-
-
33846433720
-
An osteoprotegerin-like peptidomimetic inhibits osteoclastic bone resorption and osteolytic bone disease in myeloma
-
Heath D.J., Vanderkerken K., Cheng X., et al. An osteoprotegerin-like peptidomimetic inhibits osteoclastic bone resorption and osteolytic bone disease in myeloma. Cancer Res 67 1 (2007) 202-208
-
(2007)
Cancer Res
, vol.67
, Issue.1
, pp. 202-208
-
-
Heath, D.J.1
Vanderkerken, K.2
Cheng, X.3
-
62
-
-
0038336667
-
Neoplastic development in plasma cells
-
Potter M. Neoplastic development in plasma cells. Immunol Rev 194 (2003) 177-195
-
(2003)
Immunol Rev
, vol.194
, pp. 177-195
-
-
Potter, M.1
-
63
-
-
0041331741
-
Increased bone remodeling due to ovariectomy dramatically increases tumoral growth in the 5T2 multiple myeloma mouse model
-
Libouban H., Moreau M.F., Basle M.F., et al. Increased bone remodeling due to ovariectomy dramatically increases tumoral growth in the 5T2 multiple myeloma mouse model. Bone 33 3 (2003) 283-292
-
(2003)
Bone
, vol.33
, Issue.3
, pp. 283-292
-
-
Libouban, H.1
Moreau, M.F.2
Basle, M.F.3
-
64
-
-
0037303261
-
Bisphosphonates and osteoprotegerin as inhibitors of myeloma bone disease
-
Croucher P.I., Shipman C.M., Van Camp B., et al. Bisphosphonates and osteoprotegerin as inhibitors of myeloma bone disease. Cancer 97 3 Suppl (2003) 818-824
-
(2003)
Cancer
, vol.97
, Issue.3 SUPPL
, pp. 818-824
-
-
Croucher, P.I.1
Shipman, C.M.2
Van Camp, B.3
-
65
-
-
0037238062
-
Selective in vivo growth of lymphocyte function- associated antigen-1-positive murine myeloma cells. Involvement of function-associated antigen-1-mediated homotypic cell-cell adhesion
-
Asosingh K., Vankerkhove V., Van Riet I., et al. Selective in vivo growth of lymphocyte function- associated antigen-1-positive murine myeloma cells. Involvement of function-associated antigen-1-mediated homotypic cell-cell adhesion. Exp Hematol 31 1 (2003) 48-55
-
(2003)
Exp Hematol
, vol.31
, Issue.1
, pp. 48-55
-
-
Asosingh, K.1
Vankerkhove, V.2
Van Riet, I.3
-
66
-
-
0141498246
-
Migration, adhesion and differentiation of malignant plasma cells in the 5T murine model of myeloma
-
Asosingh K. Migration, adhesion and differentiation of malignant plasma cells in the 5T murine model of myeloma. Verh K Acad Geneeskd Belg 65 2 (2003) 127-134
-
(2003)
Verh K Acad Geneeskd Belg
, vol.65
, Issue.2
, pp. 127-134
-
-
Asosingh, K.1
-
67
-
-
0036186907
-
Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells
-
Vanderkerken K., Vande Broek I., Eizirik D.L., et al. Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells. Clin Exp Metastasis 19 1 (2002) 87-90
-
(2002)
Clin Exp Metastasis
, vol.19
, Issue.1
, pp. 87-90
-
-
Vanderkerken, K.1
Vande Broek, I.2
Eizirik, D.L.3
-
68
-
-
18344376170
-
Murine 5T multiple myeloma cells induce angiogenesis in vitro and in vivo
-
Van Valckenborgh E., De Raeve H., Devy L., et al. Murine 5T multiple myeloma cells induce angiogenesis in vitro and in vivo. Br J Cancer 86 5 (2002) 796-802
-
(2002)
Br J Cancer
, vol.86
, Issue.5
, pp. 796-802
-
-
Van Valckenborgh, E.1
De Raeve, H.2
Devy, L.3
-
69
-
-
0037145325
-
Upregulation of matrix metalloproteinase-9 in murine 5T33 multiple myeloma cells by interaction with bone marrow endothelial cells
-
Van Valckenborgh E., Bakkus M., Munaut C., et al. Upregulation of matrix metalloproteinase-9 in murine 5T33 multiple myeloma cells by interaction with bone marrow endothelial cells. Int J Cancer 101 6 (2002) 512-518
-
(2002)
Int J Cancer
, vol.101
, Issue.6
, pp. 512-518
-
-
Van Valckenborgh, E.1
Bakkus, M.2
Munaut, C.3
-
70
-
-
0036959475
-
The F-actin content of multiple myeloma cells as a measure of their migration
-
Menu E., Braet F., Timmers M., et al. The F-actin content of multiple myeloma cells as a measure of their migration. Ann N Y Acad Sci 973 (2002) 124-136
-
(2002)
Ann N Y Acad Sci
, vol.973
, pp. 124-136
-
-
Menu, E.1
Braet, F.2
Timmers, M.3
-
71
-
-
0036459199
-
Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma
-
Asosingh K., Menu E., Van Valckenborgh E., et al. Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma. Clin Exp Metastasis 19 7 (2002) 583-591
-
(2002)
Clin Exp Metastasis
, vol.19
, Issue.7
, pp. 583-591
-
-
Asosingh, K.1
Menu, E.2
Van Valckenborgh, E.3
-
72
-
-
0035942272
-
Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models
-
Mittelman M., Neumann D., Peled A., et al. Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models. Proc Natl Acad Sci U S A 98 9 (2001) 5181-5186
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.9
, pp. 5181-5186
-
-
Mittelman, M.1
Neumann, D.2
Peled, A.3
-
73
-
-
0035105419
-
Purging of myeloma cells using all-trans retinoic acid in a mouse model
-
Henry J.M., Morley A.A., and Sykes P.J. Purging of myeloma cells using all-trans retinoic acid in a mouse model. Exp Hematol 29 3 (2001) 315-321
-
(2001)
Exp Hematol
, vol.29
, Issue.3
, pp. 315-321
-
-
Henry, J.M.1
Morley, A.A.2
Sykes, P.J.3
-
74
-
-
0034895198
-
Myeloma isotype-switch variants in the murine 5T myeloma model: evidence that myeloma IgM and IgA expressing subclones can originate from the IgG expressing tumour
-
Bakkus M.H., Asosingh K., Vanderkerken K., et al. Myeloma isotype-switch variants in the murine 5T myeloma model: evidence that myeloma IgM and IgA expressing subclones can originate from the IgG expressing tumour. Leukemia 15 7 (2001) 1127-1132
-
(2001)
Leukemia
, vol.15
, Issue.7
, pp. 1127-1132
-
-
Bakkus, M.H.1
Asosingh, K.2
Vanderkerken, K.3
-
75
-
-
0035300537
-
A unique pathway in the homing of murine multiple myeloma cells: CD44v10 mediates binding to bone marrow endothelium
-
Asosingh K., Gunthert U., De Raeve H., et al. A unique pathway in the homing of murine multiple myeloma cells: CD44v10 mediates binding to bone marrow endothelium. Cancer Res 61 7 (2001) 2862-2865
-
(2001)
Cancer Res
, vol.61
, Issue.7
, pp. 2862-2865
-
-
Asosingh, K.1
Gunthert, U.2
De Raeve, H.3
-
76
-
-
0035164061
-
In vivo homing and differentiation characteristics of mature (CD45-) and immature (CD45+) 5T multiple myeloma cells
-
Asosingh K., De Raeve H., Croucher P., et al. In vivo homing and differentiation characteristics of mature (CD45-) and immature (CD45+) 5T multiple myeloma cells. Exp Hematol 29 1 (2001) 77-84
-
(2001)
Exp Hematol
, vol.29
, Issue.1
, pp. 77-84
-
-
Asosingh, K.1
De Raeve, H.2
Croucher, P.3
-
78
-
-
0033973841
-
Selective initial in vivo homing pattern of 5T2 multiple myeloma cells in the C57BL/KalwRij mouse
-
Vanderkerken K., De Greef C., Asosingh K., et al. Selective initial in vivo homing pattern of 5T2 multiple myeloma cells in the C57BL/KalwRij mouse. Br J Cancer 82 4 (2000) 953-959
-
(2000)
Br J Cancer
, vol.82
, Issue.4
, pp. 953-959
-
-
Vanderkerken, K.1
De Greef, C.2
Asosingh, K.3
-
79
-
-
0034094950
-
Absence of herpesvirus DNA sequences in the 5T murine model of human multiple myeloma
-
Oyajobi B.O., Deng J.H., Dallas S.L., et al. Absence of herpesvirus DNA sequences in the 5T murine model of human multiple myeloma. Br J Haematol 109 2 (2000) 413-419
-
(2000)
Br J Haematol
, vol.109
, Issue.2
, pp. 413-419
-
-
Oyajobi, B.O.1
Deng, J.H.2
Dallas, S.L.3
-
80
-
-
0034584607
-
The 5TMM series: a useful in vivo mouse model of human multiple myeloma
-
Asosingh K., Radl J., Van Riet I., et al. The 5TMM series: a useful in vivo mouse model of human multiple myeloma. Hematol J 1 5 (2000) 351-356
-
(2000)
Hematol J
, vol.1
, Issue.5
, pp. 351-356
-
-
Asosingh, K.1
Radl, J.2
Van Riet, I.3
-
81
-
-
0032939906
-
Insulin-like growth factor-1 acts as a chemoattractant factor for 5T2 multiple myeloma cells
-
Vanderkerken K., Asosingh K., Braet F., et al. Insulin-like growth factor-1 acts as a chemoattractant factor for 5T2 multiple myeloma cells. Blood 93 1 (1999) 235-241
-
(1999)
Blood
, vol.93
, Issue.1
, pp. 235-241
-
-
Vanderkerken, K.1
Asosingh, K.2
Braet, F.3
-
82
-
-
0032698788
-
Effects of the glucolipid synthase inhibitor, P4, on functional and phenotypic parameters of murine myeloma cells
-
Manning L.S., and Radin N.S. Effects of the glucolipid synthase inhibitor, P4, on functional and phenotypic parameters of murine myeloma cells. Br J Cancer 81 6 (1999) 952-958
-
(1999)
Br J Cancer
, vol.81
, Issue.6
, pp. 952-958
-
-
Manning, L.S.1
Radin, N.S.2
-
83
-
-
0031595998
-
Immunoglobulin VH gene sequence analysis of spontaneous murine immunoglobulin-secreting B-cell tumours with clinical features of human disease
-
Zhu D., van Arkel C., King C.A., et al. Immunoglobulin VH gene sequence analysis of spontaneous murine immunoglobulin-secreting B-cell tumours with clinical features of human disease. Immunology 93 2 (1998) 162-170
-
(1998)
Immunology
, vol.93
, Issue.2
, pp. 162-170
-
-
Zhu, D.1
van Arkel, C.2
King, C.A.3
-
84
-
-
0030749836
-
Organ involvement and phenotypic adhesion profile of 5T2 and 5T33 myeloma cells in the C57BL/KaLwRij mouse
-
Vanderkerken K., De Raeve H., Goes E., et al. Organ involvement and phenotypic adhesion profile of 5T2 and 5T33 myeloma cells in the C57BL/KaLwRij mouse. Br J Cancer 76 4 (1997) 451-460
-
(1997)
Br J Cancer
, vol.76
, Issue.4
, pp. 451-460
-
-
Vanderkerken, K.1
De Raeve, H.2
Goes, E.3
-
85
-
-
0030056093
-
Follow-up of bone lesions in an experimental multiple myeloma mouse model: description of an in vivo technique using radiography dedicated for mammography
-
Vanderkerken K., Goes E., De Raeve H., et al. Follow-up of bone lesions in an experimental multiple myeloma mouse model: description of an in vivo technique using radiography dedicated for mammography. Br J Cancer 73 12 (1996) 1463-1465
-
(1996)
Br J Cancer
, vol.73
, Issue.12
, pp. 1463-1465
-
-
Vanderkerken, K.1
Goes, E.2
De Raeve, H.3
-
86
-
-
0029978141
-
Cytogenetic findings in mouse multiple myeloma and Waldenstrom's macroglobulinemia
-
van den Akker T.W., Radl J., Franken-Postma E., et al. Cytogenetic findings in mouse multiple myeloma and Waldenstrom's macroglobulinemia. Cancer Genet Cytogenet 86 2 (1996) 156-161
-
(1996)
Cancer Genet Cytogenet
, vol.86
, Issue.2
, pp. 156-161
-
-
van den Akker, T.W.1
Radl, J.2
Franken-Postma, E.3
-
87
-
-
0029966306
-
Interaction between a murine myeloma cell line and bone marrow stromal cells
-
Bradley T.R., Kriegler A.B., Verschoor S.M., et al. Interaction between a murine myeloma cell line and bone marrow stromal cells. Exp Hematol 24 2 (1996) 307-309
-
(1996)
Exp Hematol
, vol.24
, Issue.2
, pp. 307-309
-
-
Bradley, T.R.1
Kriegler, A.B.2
Verschoor, S.M.3
-
88
-
-
0029114293
-
Assessment of the therapeutic potential of cytokines, cytotoxic drugs and effector cell populations for the treatment of multiple myeloma using the 5T33 murine myeloma model
-
Manning L.S., Chamberlain N.L., Leahy M.F., et al. Assessment of the therapeutic potential of cytokines, cytotoxic drugs and effector cell populations for the treatment of multiple myeloma using the 5T33 murine myeloma model. Immunol Cell Biol 73 4 (1995) 326-332
-
(1995)
Immunol Cell Biol
, vol.73
, Issue.4
, pp. 326-332
-
-
Manning, L.S.1
Chamberlain, N.L.2
Leahy, M.F.3
-
89
-
-
0027290533
-
Radiopharmaceutical therapy of 5T33 murine myeloma by sequential treatment with samarium-153 ethylenediaminetetramethylene phosphonate, melphalan, and bone marrow transplantation
-
Turner J.H., Claringbold P.G., Manning L.S., et al. Radiopharmaceutical therapy of 5T33 murine myeloma by sequential treatment with samarium-153 ethylenediaminetetramethylene phosphonate, melphalan, and bone marrow transplantation. J Natl Cancer Inst 85 18 (1993) 1508-1513
-
(1993)
J Natl Cancer Inst
, vol.85
, Issue.18
, pp. 1508-1513
-
-
Turner, J.H.1
Claringbold, P.G.2
Manning, L.S.3
-
90
-
-
0027085782
-
A model of multiple myeloma: culture of 5T33 murine myeloma cells and evaluation of tumorigenicity in the C57BL/KaLwRij mouse
-
Manning L.S., Berger J.D., O'Donoghue H.L., et al. A model of multiple myeloma: culture of 5T33 murine myeloma cells and evaluation of tumorigenicity in the C57BL/KaLwRij mouse. Br J Cancer 66 6 (1992) 1088-1093
-
(1992)
Br J Cancer
, vol.66
, Issue.6
, pp. 1088-1093
-
-
Manning, L.S.1
Berger, J.D.2
O'Donoghue, H.L.3
-
91
-
-
0025985310
-
Immune regulation of mouse 5T2 multiple myeloma. I. Immune response to 5T2 MM idiotype
-
Croese J.W., Vissinga C.S., Boersma W.J., et al. Immune regulation of mouse 5T2 multiple myeloma. I. Immune response to 5T2 MM idiotype. Neoplasma 38 5 (1991) 457-466
-
(1991)
Neoplasma
, vol.38
, Issue.5
, pp. 457-466
-
-
Croese, J.W.1
Vissinga, C.S.2
Boersma, W.J.3
-
92
-
-
0025932042
-
Immune regulation of 5T2 mouse multiple myeloma. II. Immunological treatment of 5T2 MM residual disease
-
Croese J.W., Van den Enden-Vieveen M.H., and Radl J. Immune regulation of 5T2 mouse multiple myeloma. II. Immunological treatment of 5T2 MM residual disease. Neoplasma 38 5 (1991) 467-474
-
(1991)
Neoplasma
, vol.38
, Issue.5
, pp. 467-474
-
-
Croese, J.W.1
Van den Enden-Vieveen, M.H.2
Radl, J.3
-
93
-
-
0025176944
-
The 5T mouse multiple myeloma model: absence of c-myc oncogene rearrangement in early transplant generations
-
Radl J., Punt Y.A., van den Enden-Vieveen M.H., et al. The 5T mouse multiple myeloma model: absence of c-myc oncogene rearrangement in early transplant generations. Br J Cancer 61 2 (1990) 276-278
-
(1990)
Br J Cancer
, vol.61
, Issue.2
, pp. 276-278
-
-
Radl, J.1
Punt, Y.A.2
van den Enden-Vieveen, M.H.3
-
94
-
-
0023628690
-
The 5T2 mouse multiple myeloma model: characterization of 5T2 cells within the bone marrow
-
Croese J.W., Vas Nunes C.M., Radl J., et al. The 5T2 mouse multiple myeloma model: characterization of 5T2 cells within the bone marrow. Br J Cancer 56 5 (1987) 555-560
-
(1987)
Br J Cancer
, vol.56
, Issue.5
, pp. 555-560
-
-
Croese, J.W.1
Vas Nunes, C.M.2
Radl, J.3
-
95
-
-
0021907418
-
Influence of treatment with APD-bisphosphonate on the bone lesions in the mouse 5T2 multiple myeloma
-
Radl J., Croese J.W., Zurcher C., et al. Influence of treatment with APD-bisphosphonate on the bone lesions in the mouse 5T2 multiple myeloma. Cancer 55 5 (1985) 1030-1040
-
(1985)
Cancer
, vol.55
, Issue.5
, pp. 1030-1040
-
-
Radl, J.1
Croese, J.W.2
Zurcher, C.3
-
96
-
-
0018128194
-
Idiopathic paraproteinaemia. I. Studies in an animal model-the ageing C57BL/KaLwRij mouse
-
Radl J., Hollander C.F., van den Berg P., et al. Idiopathic paraproteinaemia. I. Studies in an animal model-the ageing C57BL/KaLwRij mouse. Clin Exp Immunol 33 3 (1978) 395-402
-
(1978)
Clin Exp Immunol
, vol.33
, Issue.3
, pp. 395-402
-
-
Radl, J.1
Hollander, C.F.2
van den Berg, P.3
-
97
-
-
33751190044
-
Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model
-
Menu E., De Leenheer E., De Raeve H., et al. Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model. Clin Exp Metastasis 23 5-6 (2006) 291-300
-
(2006)
Clin Exp Metastasis
, vol.23
, Issue.5-6
, pp. 291-300
-
-
Menu, E.1
De Leenheer, E.2
De Raeve, H.3
-
98
-
-
33744467387
-
The involvement of stromal derived factor 1alpha in homing and progression of multiple myeloma in the 5TMM model
-
Menu E., Asosingh K., Indraccolo S., et al. The involvement of stromal derived factor 1alpha in homing and progression of multiple myeloma in the 5TMM model. Haematologica 91 5 (2006) 605-612
-
(2006)
Haematologica
, vol.91
, Issue.5
, pp. 605-612
-
-
Menu, E.1
Asosingh, K.2
Indraccolo, S.3
-
99
-
-
21244460271
-
Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression
-
Asosingh K., De Raeve H., de Ridder M., et al. Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression. Haematologica 90 6 (2005) 810-817
-
(2005)
Haematologica
, vol.90
, Issue.6
, pp. 810-817
-
-
Asosingh, K.1
De Raeve, H.2
de Ridder, M.3
-
100
-
-
0242308942
-
Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival
-
Croucher P.I., De Hendrik R., Perry M.J., et al. Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival. J Bone Miner Res 18 3 (2003) 482-492
-
(2003)
J Bone Miner Res
, vol.18
, Issue.3
, pp. 482-492
-
-
Croucher, P.I.1
De Hendrik, R.2
Perry, M.J.3
-
101
-
-
30444446821
-
Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model
-
Menu E., Jernberg-Wiklund H., Stromberg T., et al. Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model. Blood 107 2 (2006) 655-660
-
(2006)
Blood
, vol.107
, Issue.2
, pp. 655-660
-
-
Menu, E.1
Jernberg-Wiklund, H.2
Stromberg, T.3
-
102
-
-
33947161063
-
Apominetrade mark, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo
-
Edwards C.M., Mueller G., Roelofs A.J., et al. Apominetrade mark, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo. Int J Cancer 120 8 (2007) 1657-1663
-
(2007)
Int J Cancer
, vol.120
, Issue.8
, pp. 1657-1663
-
-
Edwards, C.M.1
Mueller, G.2
Roelofs, A.J.3
-
103
-
-
1642333882
-
Selection of a highly aggressive myeloma cell line by an altered bone microenvironment in the C57BL/KaLwRij mouse
-
Libouban H., Moreau M.F., Basle M.F., et al. Selection of a highly aggressive myeloma cell line by an altered bone microenvironment in the C57BL/KaLwRij mouse. Biochem Biophys Res Commun 316 3 (2004) 859-866
-
(2004)
Biochem Biophys Res Commun
, vol.316
, Issue.3
, pp. 859-866
-
-
Libouban, H.1
Moreau, M.F.2
Basle, M.F.3
-
104
-
-
33747121704
-
LAGlambda-1: a clinically relevant drug resistant human multiple myeloma tumor murine model that enables rapid evaluation of treatments for multiple myeloma
-
Campbell R.A., Manyak S.J., Yang H.H., et al. LAGlambda-1: a clinically relevant drug resistant human multiple myeloma tumor murine model that enables rapid evaluation of treatments for multiple myeloma. Int J Oncol 28 6 (2006) 1409-1417
-
(2006)
Int J Oncol
, vol.28
, Issue.6
, pp. 1409-1417
-
-
Campbell, R.A.1
Manyak, S.J.2
Yang, H.H.3
-
105
-
-
0038675136
-
The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response
-
Iwakoshi N.N., Lee A.H., and Glimcher L.H. The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response. Immunol Rev 194 (2003) 29-38
-
(2003)
Immunol Rev
, vol.194
, pp. 29-38
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Glimcher, L.H.3
-
106
-
-
0033020874
-
Multiple myeloma and related disorders. Lessons from an animal model
-
Radl J. Multiple myeloma and related disorders. Lessons from an animal model. Pathol Biol (Paris) 47 2 (1999) 109-114
-
(1999)
Pathol Biol (Paris)
, vol.47
, Issue.2
, pp. 109-114
-
-
Radl, J.1
-
107
-
-
0031001374
-
Experimental plasmacytomagenesis in mice
-
Potter M. Experimental plasmacytomagenesis in mice. Hematol Oncol Clin North Am 11 2 (1997) 323-347
-
(1997)
Hematol Oncol Clin North Am
, vol.11
, Issue.2
, pp. 323-347
-
-
Potter, M.1
-
108
-
-
0034751091
-
Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility
-
Zhang S.L., DuBois W., Ramsay E.S., et al. Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility. Mol Cell Biol 21 1 (2001) 310-318
-
(2001)
Mol Cell Biol
, vol.21
, Issue.1
, pp. 310-318
-
-
Zhang, S.L.1
DuBois, W.2
Ramsay, E.S.3
-
109
-
-
0037022341
-
IL-6 transgenic mouse model for extraosseous plasmacytoma
-
Kovalchuk A.L., Kim J.S., Park S.S., et al. IL-6 transgenic mouse model for extraosseous plasmacytoma. Proc Natl Acad Sci U S A 99 3 (2002) 1509-1514
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.3
, pp. 1509-1514
-
-
Kovalchuk, A.L.1
Kim, J.S.2
Park, S.S.3
-
110
-
-
0037372285
-
NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors
-
Chiarle R., Gong J.Z., Guasparri I., et al. NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood 101 5 (2003) 1919-1927
-
(2003)
Blood
, vol.101
, Issue.5
, pp. 1919-1927
-
-
Chiarle, R.1
Gong, J.Z.2
Guasparri, I.3
-
111
-
-
3042806890
-
Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice
-
Cheung W.C., Kim J.S., Linden M., et al. Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice. J Clin Invest 113 12 (2004) 1763-1773
-
(2004)
J Clin Invest
, vol.113
, Issue.12
, pp. 1763-1773
-
-
Cheung, W.C.1
Kim, J.S.2
Linden, M.3
-
112
-
-
33645976496
-
Plasma cell tumour progression in iMycEmu gene-insertion mice
-
Kim J.S., Han S.S., Park S.S., et al. Plasma cell tumour progression in iMycEmu gene-insertion mice. J Pathol 209 1 (2006) 44-55
-
(2006)
J Pathol
, vol.209
, Issue.1
, pp. 44-55
-
-
Kim, J.S.1
Han, S.S.2
Park, S.S.3
-
113
-
-
35748948001
-
A novel transgenic mouse model of multiple myeloma reliably predicts drug response
-
Sebag M., Stewart K., Palmer S., et al. A novel transgenic mouse model of multiple myeloma reliably predicts drug response. Blood 108 11 (2006) 75a
-
(2006)
Blood
, vol.108
, Issue.11
-
-
Sebag, M.1
Stewart, K.2
Palmer, S.3
-
114
-
-
34047136169
-
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
-
Carrasco D.R., Sukhdeo K., Protopopova M., et al. The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell 11 4 (2007) 349-360
-
(2007)
Cancer Cell
, vol.11
, Issue.4
, pp. 349-360
-
-
Carrasco, D.R.1
Sukhdeo, K.2
Protopopova, M.3
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