Effectiveness and stability of heterologous proteins expressed in plants by Turnip mosaic virus vector at five different insertion sites

Virus Research

Volumn 130, Issue 1-2, 2007, Pages 210-227

  Chen, Chin Chih ^a,b   Chen, Tsung Chi ^a   Raja, Joseph A J ^a   Chang, Chin An ^b   Chen, Li Wen ^b   Lin, Shih Shun ^a   Yeh, Shyi Dong ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b TAIWAN AGRICULTURAL RESEARCH INSTITUTE   (Taiwan)

Author keywords

Dust mite allergen Der p 5; Insertion sites; Plant expression; Potyvirus; Stability; TuMV vector

Indexed keywords

ALLERGEN; DER P 5 ALLERGEN; GREEN FLUORESCENT PROTEIN; HOUSE DUST ALLERGEN; POLYPROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS VECTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CHENOPODIUM QUINOA; CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; GENE INSERTION SEQUENCE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; TURNIP YELLOW MOSAIC VIRUS;

ANTIGENS, DERMATOPHAGOIDES; BRASSICA; CHENOPODIUM QUINOA; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; PLANTS, GENETICALLY MODIFIED; POLYPROTEINS; POTYVIRUS; RECOMBINANT PROTEINS; TOBACCO; VIRAL PROTEINS;

ACARI; BRASSICA; BRASSICA JUNCEA; BRASSICA RAPA; CHENOPODIUM QUINOA; DERMATOPHAGOIDES PTERONYSSINUS; NICOTIANA BENTHAMIANA; POTYVIRUS; SCYPHOZOA; TURNIP MOSAIC VIRUS;

EID: 35748937943     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2007.06.014     Document Type: Article

References (57)

1. Arazi T., Lee Huang P., Huang P.L., Zhang L., Moshe Shiboleth Y., Gal-On A., and Lee-Huang S. Production of antiviral and antitumor proteins MAP30 and GAP31 in cucurbits using the plant virus vector ZYMV-AGII. Biochem. Biophys. Res. Commun. 292 (2002) 441-448
2. Arazi T., Shiboleth Y.M., and Gal-On A. A nonviral peptide can replace the entire N terminus of Zucchini Yellow Mosaic potyvirus coat protein and permits viral systemic infection. J. Virol. 75 (2001) 5975-6329
3. Arazi T., Slutsky S.G., Shiboleth Y.M., Wang Y., Rubinstein M., Barak S., Yang J., and Gal-On A. Engineering zucchini yellow mosaic potyvirus as a non-pathogenic vector for expression of heterologous proteins in cucurbits. J. Biotechnol. 87 (2001) 67-82
4. Beauchemin C., Bougie V., and Laliberté J.F. Stimultaneous production of two foreign proteins from a potyvirus-based vector. Virus Res. 112 (2005) 1-8
5. Brennan F.R., Jones T.D., and Hamilton W.D.O. Cowpea mosaic virus as a vaccine carrier of heterologous antigens. Mol. Biotechnol. 17 (2001) 15-26
6. Carrington J.C., Freed D.D., and Sanders T.C. Autocatalytic processing of the potyvirus helper component proteinase in Escherichia coli and in vitro. J. Virol. 63 (1989) 4459-4463
7. Carrington J.C., Haldeman R., Dolja V.V., and Restrepo-Hartwig M.A. Internal cleavage and trans-proteolytic activities of the VPg-proteinase (NIa) of tobacco etch potyvirus in vivo. J. Virol. 67 (1993) 6995-7000
8. Carrington J.C., Jensen P.E., and Schaad M.C. Genetic evidence for an essential role for potyvirus CI protein in cell-to-cell movement. Plant J. 14 (1998) 393-400
9. Chen, C.C. 2006. Development of Turnip mosaic virus as a plant viral vector for expressing foreign proteins and generation of attenuated strains for cross protection. Ph.D. Thesis, Department of Plant Pathology, National Chung Hsing University, Taiwan, ROC.
10. Chen C.C., Chao C.H., Chen C.C., Yeh S.D., Tsai H.T., and Chang C.A. Identification of Turnip mosaic virus isolates causing yellow stripe and spot on calla lily. Plant Dis. 87 (2003) 901-905
11. Chen C.C., Hsiang T., Chiang F.L., and Chang C.A. Molecular characterization of Tuberose mild mosaic virus and preparation of its antiserum to the coat protein expressed in bacteria. Bot. Bull. Acad. Sin. 43 (2002) 13-20
12. Choi I.R., Stenger D.C., Morries T.J., and French R. A plant virus vector for systemic expression of foreign genes in cereals. Plant J. 23 (2000) 547-555
13. Cronin S., Verchot J., Haldeman-Cahill R., Schaad M.C., and Carrington J.C. Long-distance movement factor: a transport function of the potyvirus helper component proteinase. Plant Cell 7 (1995) 549-559
14. Dietrich C., and Maiss E. Fluorescent labelling reveals spatial separation of potyvirus populations in mixed infected Nicotiana benthamiana plants. J. Gen. Virol. 84 (2003) 2871-2876
15. Dolja V.V., Haldeman R., Robertson N.L., Dougherty W.G., and Carrington J.C. Distinct functions of capsid protein in assembly and movement of tobacco etch potyvirus in plants. EMBO J. 13 (1994) 1482-1491
16. Dolja V.V., Haldeman-Cahill R., Montgomery A.E., Vandenbosch K.A., and Carrington J.C. Capsid protein determinants involved in cell-to-cell and long distance movement of tobacco etch potyvirus. Virology 206 (1995) 1007-1016
17. Dolja V.V., Herndon K.L., Pirone T.P., and Carrington J.C. Spontaneous mutagenesis of a plant potyvirus genome after insertion of a foreign gene. J. Virol. 67 (1993) 5968-5975
18. Dolja V.V., Hong J., Keller K.E., Martin R.R., and Peremyslov V.V. Suppression of potyvirus infection by coexpressed closterovirus protein. Virology 234 (1997) 243-252
19. Dolja V.V., McBride H.J., and Carrington J.C. Tagging of plant potyvirus replication and movement by insertion of beta-glucuronidase into the viral polyprotein. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 10208-10212
20. Fernández A., Guo H.S., Sáenz P., Simón-Buela L., Gómez de Cedrón M., and García J.A. The motif V of plum pox potyvirus CI RNA helicase is involved in NTP hydrolysis and is essential for virus RNA replication. Nucleic Acids Res. 25 (1997) 4474-4480
21. Fernandez-Fernandez M.R., Mourino M., Rivera J., Rodriguez F., Plana-Duran J., and Garcia J.A. Protection of rabbits against rabbit hemorrhagic disease virus by immonization with the VP60 protein expressed in plants with a potyvirus-based vector. Virology 280 (2001) 283-291
22. German-Retana S., Candresse T., Alias E., Delbos R.P., and Le Gall O. Effects of green fluorescent protein or beta-glucuronidase tagging on the accumulation and pathogenicity of a resistance-breaking Lettuce mosaic virus isolate in susceptible and resistant lettuce cultivars. Mol. Plant-Microb. Interact. 13 (2000) 316-324
23. Guo H.S., Lopez-Moya J.J., and Garcia J.A. Susceptibility to recombination rearrangements of a chimeric plum pox potyvirus genome after insertion of a foreign gene. Virus Res. 57 (1998) 183-195
24. Haldeman-Cahill R., Daros J.A., and Carrington J.C. Secondary structures in the capsid protein coding sequence and 3' nontranslated region involved in amplification of the tobacco etch virus genome. J. Virol. 72 (1998) 4072-4079
25. Hsu C.H., Lin S.S., Liu F.L., Su W.C., and Yeh S.D. Oral administration of a mite allergen expressed by zucchini yellow mosaic virus in cucurbit species downregulates allergen-induced airway inflammation and IgE synthesis. J. Allergy Clin. Immunol. 113 (2004) 1079-1085
26. Hull R. Matthews Plant Virology. fourth ed. (2002), A Harcourt Science and Technology Company, London, UK
27. Ivanov K.I., Puustinen P., Gabrenaite R., Vihinen H., Ronnstrand L., Valmu L., Kalkkinen N., and Makinen K. Phosphorylation of the potyvirus capsid protein by protein kinase CK2 and its relevance for virus infection. Plant Cell 15 (2003) 2124-2139
28. Jenner C.E., Sanchez F., Nettleship S.B., Foster G.D., Ponz F., and Walsh J.A. The cylindrical inclusion gene of Turnip mosaic virus encodes a pathogenic determinant to the brassica resistance gene TuRB01. Mol. Plant-Microb. Interact. 13 (2000) 1102-1108
29. Jenner C.E., Wang X., Tomimura K., Ohshima K., Ponz F., and Walsh J.A. The dual role of the potyvirus P3 protein of Turnip mosaic virus as a symptom and avirulence determinant in brassicas. Mol. Plant-Microb. Interact. 16 (2003) 777-784
30. Kasschau K.D., Cronin S., and Carrington J.C. Genome amplification and long-distance movement functions associated with the central domain of tobacco etch potyvirus helper component-proteinase. Virology 228 (1997) 251-262
31. Kekarainen T., Savilahti H., and Valkonen J.P.T. Functional genomics on Potato virus A: virus genome-wide map of sites essential for virus propagation. Genome Res. 12 (2002) 584-594
32. Klein P.G., Klein R.R., Rodríguez-Cerezo E., Hunt A.G., and Shaw J.G. Mutational analysis of the tobacco vein mottling virus genome. Virology 204 (1994) 759-769
33. Lellis A.D., Kasschau K.D., Whitham S.A., and Carrington J.C. Loss-of- susceptibility mutants of Arabidopsis thaliana reveal an essential role for eIF(iso)4E during potyvirus infection. Curr. Biol. 12 (2002) 1046-1051
34. Masuta C., Yamana T., Tacahashi Y., Uyeda I., Sato M., Ueda S., and Matsumura T. Development of Clover yellow vein virus as an efficient, stable gene-expression system for legume species. Plant J. 23 (2000) 539-546
35. Merits A., Guo D., Järvekülg L., and Saarma M. Biochemical and genetic evidence for interactions between potato A potyvirus-encoded proteins P1 and P3 and proteins of the putative replication complex. Virology 263 (1999) 15-22
36. Mushegian A.R., and Shepherd R.J. Genetic elements of plant viruses as tools for genetic engineering. Microbiol. Rev. 59 (1995) 548-578
37. Nicolas O., Dunnington S.W., Gotow L.F., Pirone T.P., and Hellmann G.M. Variations in the VPg protein allow a potyvirus to overcome va gene resistance in tobacco. Virology 237 (1997) 452-459
38. Pickart C.M. Ubiquitin biology: an old dog learns an old trick. Nat. Cell Biol. 2 (2000) E139-E141
39. Porta C., and Lomonossoff G.P. Viruses as vectors for the expression of foreign sequences in plants. Biotechnol. Genet. Eng. Rev. 19 (2002) 245-291
40. Rajamaki M.L., Kelloniemi J., Alminaite A., Kekarainen T., Rabenstein F., and Valkonen J.P.T. A novel insertion site inside the potyvirus P1 cistron allows expression of heterologous proteins and suggests some P1 functions. Virology 342 (2005) 88-101
41. Revers F., Le Gall O., Candresse T., and Maule A.J. New advances in understanding the molecular biology of plant/potyvirus interactions. Mol. Plant-Microb. Interact. 12 (1999) 367-376
42. Riechmann J.L., Lain S., and Garcia J.A. Highlights and prospects of potyvirus molecular biology. J. Gen. Virol. 73 (1992) 1-16
43. Rojas M.R., Zerbini F.M., Allison R.F., Gilbertson R.L., and Lucas W.J. Capsid protein and helper component-proteinase functions as potyvirus cell-to-cell movement proteins. Virology 237 (1997) 283-295
44. Schaad M.C., Carrington A.D., and Lellis J.C. VPg of tobacco etch potyvirus is a host genotype-specific determinant for long distance movement. J. Virol. 71 (1997) 8624-8631
45. Scholthof H.B., Scholthof K.B.G., and Jackson A.O. Plant virus gene vectors for transient expression of foreign proteins in plants. Annu. Rev. Phytopathol. 34 (1996) 299-323
46. Shukla D.D., Ward C.W., and Brunt A.A. The Potyviridae (1994), CAB International, Wallingford p. 516
47. Suehiro N., Natsuaki T., Watanabe T., and Okuda S. An important determinant of the ability of Turnip mosaic virus to infect Brassica spp. and/or Raphanus sativus is in its P3 protein. J. Gen. Virol. 85 (2004) 2087-2098
48. Sugiyama Y., Hamamoto H., Takemoto S., Watanabe Y., and Okada Y. Systemic production of foreign peptides on the particle surface of tobacco mosaic virus. FEBS Lett. 359 (1995) 247-250
49. Tan Z., Gibbs A.J., Tomitaka Y., Sanchez F., Ponz F., and Ohshima K. Mutations in Turnip mosaic virus genomes that have adapted to Raphanus sativus. J. Gen. Virol. 86 (2005) 501-510
50. Tomlinson J.A. Epidemiology and control of virus diseases of vegetables. Ann. Appl. Biol. 110 (1987) 661-681
51. Urcuqui-Inchima S., Haenni A.L., and Bernardi F. Potyvirus proteins: a wealth of functions. Virus Res. 74 (2001) 157-175
52. Van Vloten-Doting L., Bol J.F., and Cornelissen B. Plant virus-based vectors for gene transfer will be of limited use because of the high error frequency during viral RNA synthesis. Plant Mol. Biol. 4 (1985) 323-26361
53. Varshavsky A. The N-end rule: functions, mysteries, uses. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 12142-12149
54. Varshavsky A. The N-end rule pathway of protein degradation. Genes Cells 2 (1997) 13-28
55. Varshavsky A., Byrd C., Davydov I.V., Dohmen R.J., Du F., Ghislain M., Gonzalez M., Grigoryev S., Johnson E.S., Johnsson N., Johnston J.A., Kwon Y.T., Le'vy F., Lomovskaya O., Madura K., Ota I., Ru'menapf T., Shrader T.E., Suzuki T., Turner G., Waller P.R.H., and Webster A. The N-end rule pathway. In: Peters J.-M., Harris J.R., and Finley D. (Eds). Ubiquitin and the Biology of the Cell (1998), Plenum Press, New York, NY 223-278
56. Verchot J., Koonin E.V., and Carrington J.C. The 35-kDa protein from the N-terminus of the potyviral polyprotein functions as a third virus-encoded proteinase. Virology 185 (1991) 527-535
57. Worley C.K., Ling R., and Callis J. Engineering in vivo instability of firefly luciferase and Escherichia coli β-glucuronidase in higher plants using recognition elements from the ubiquitin pathway. Plant Mol. Biol. 37 (1998) 337-347