Expression of IL-9 receptor α chain on human germinal center B cells modulates IgE secretion

Journal of Allergy and Clinical Immunology

Volumn 120, Issue 5, 2007, Pages 1208-1215

  Fawaz, Lama M ^a,b   Sharif Askari, Ehssan ^c   Hajoui, Oumnia ^b   Soussi Gounni, Abdelilah ^d   Hamid, Qutayba ^b   Mazer, Bruce D ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF MANITOBA   (Canada)

Author keywords

B cell maturation; Germinal center B cells; IgE; IL 9

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 9 RECEPTOR;

ARTICLE; B LYMPHOCYTE; CELL DENSITY; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GERMINAL CENTER; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANTIGENS, CD27; B-LYMPHOCYTES; CELLS, CULTURED; GERMINAL CENTER; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-4; INTERLEUKIN-9; PHOSPHORYLATION; RECEPTORS, INTERLEUKIN-9; TONSIL; UP-REGULATION;

EID: 35648997017     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.08.022     Document Type: Article

References (34)

1. Hendriks R.W., and Middendorp S. The pre-BCR checkpoint as a cell-autonomous proliferation switch. Trends Immunol 25 (2004) 249-256
2. Loder F., Mutschler B., Ray R.J., Paige C.J., Sideras P., Torres R., et al. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J Exp Med 190 (1999) 75-89
3. Chung J.B., Silverman M., and Monroe J.G. Transitional B cells: step by step towards immune competence. Trends Immunol 24 (2003) 343-349
4. Petit-Frere C., Dugas B., Braquet P., and Mencia-Huerta J.M. Interleukin-9 potentiates the interleukin-4-induced IgE and IgG1 release from murine B lymphocytes. Immunology 79 (1993) 146-151
5. Nicolaides N.C., Holroyd K.J., Ewart S.L., Eleff S.M., Kiser M.B., Dragwa C.R., et al. Interleukin 9: a candidate gene for asthma. Proc Natl Acad Sci U S A 94 (1997) 13175-13180
6. Marsh D.G., Neely J.D., Breazeale D.R., Ghosh B., Freidhoff L.R., Ehrlich-Kautzky E., et al. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 264 (1994) 1152-1156
7. Renauld J.C., van der L.N., Vink A., van Roon M., Godfraind C., Warnier G., et al. Thymic lymphomas in interleukin 9 transgenic mice. Oncogene 9 (1994) 1327-1332
8. Temann U.A., Geba G.P., Rankin J.A., and Flavell R.A. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J Exp Med 188 (1998) 1307-1320
9. McLane M.P., Haczku A., van de R.M., Weiss C., Ferrante V., MacDonald D., et al. Interleukin-9 promotes allergen-induced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice. Am J Respir Cell Mol Biol 19 (1998) 713-720
10. Busslinger M. Transcriptional control of early B cell development. Annu Rev Immunol 22 (2004) 55-79
11. Gounni A.S., Lamkhioued B., Koussih L., Ra C., Renzi P.M., and Hamid Q. Human neutrophils express the high-affinity receptor for immunoglobulin E (Fc epsilon RI): role in asthma. FASEB J 15 (2001) 940-949
12. Dong Q., Louahed J., Vink A., Sullivan C.D., Messler C.J., Zhou Y., et al. IL-9 induces chemokine expression in lung epithelial cells and baseline airway eosinophilia in transgenic mice. Eur J Immunol 29 (1999) 2130-2139
13. Louahed J., Toda M., Jen J., Hamid Q., Renauld J.C., Levitt R.C., et al. Interleukin-9 upregulates mucus expression in the airways. Am J Respir Cell Mol Biol 22 (2000) 649-656
14. Baraldo S., Faffe D.S., Moore P.E., Whitehead T., McKenna M., Silverman E.S., et al. Interleukin-9 influences chemokine release in airway smooth muscle: role of ERK. Am J Physiol Lung Cell Mol Physiol 284 (2003) L1093-L1102
15. Liu Y.J., Joshua D.E., Williams G.T., Smith C.A., Gordon J., and MacLennan I.C. Mechanism of antigen-driven selection in germinal centres. Nature 342 (1989) 929-931
16. Suzuki N., Ueda Y., and Sakane T. Differential mechanism for differentiation into immunoglobulin-secreting cells in human resting B lymphocyte subsets isolated on the basis of cell density. J Clin Invest 81 (1988) 261-269
17. Bastien Y., Toledano B.J., Mehio N., Cameron L., Lamoukhaid B., Renzi P., et al. Detection of functional platelet-activating factor receptors on human tonsillar B lymphocytes. J Immunol 162 (1999) 5498-5505
18. Chow S., Patel H., and Hedley D.W. Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors. Cytometry 46 (2001) 72-78
19. Hajoui O., Janani R., Tulic M., Joubert P., Ronis T., Hamid Q., et al. Synthesis of IL-13 by human B lymphocytes: regulation and role in IgE production. J Allergy Clin Immunol 114 (2004) 657-663
20. Liu Y.J., and Arpin C. Germinal center development. Immunol Rev 156 (1997) 111-126
21. Demoulin J.B., Van Roost E., Stevens M., Groner B., and Renauld J.C. Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9. J Biol Chem 274 (1999) 25855-25861
22. Demoulin J.B., Uyttenhove C., Van Roost E., DeLestre B., Donckers D., Van Snick J., et al. A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9. Mol Cell Biol 16 (1996) 4710-4716
23. McHeyzer-Williams L.J., and McHeyzer-Williams M.G. Antigen-specific memory B cell development. Annu Rev Immunol 23 (2005) 487-513
24. Steiniger B., Timphus E.M., Jacob R., and Barth P.J. CD27+ B cells in human lymphatic organs: re-evaluating the splenic marginal zone. Immunology 116 (2005) 429-442
25. Demoulin J.B., Uyttenhove C., Lejeune D., Mui A., Groner B., and Renauld J.C. STAT5 activation is required for interleukin-9-dependent growth and transformation of lymphoid cells. Cancer Res 60 (2000) 3971-3977
26. Fornek J.L., Tygrett L.T., Waldschmidt T.J., Poli V., Rickert R.C., and Kansas G.S. Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells. Blood 107 (2006) 1085-1091
27. Demoulin J.B., Van Snick J., and Renauld J.C. Interleukin-9 (IL-9) induces cell growth arrest associated with sustained signal transducer and activator of transcription activation in lymphoma cells overexpressing the IL-9 receptor. Cell Growth Differ 12 (2001) 169-174
28. Scheeren F.A., Naspetti M., Diehl S., Schotte R., Nagasawa M., Wijnands E., et al. STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression. Nat Immunol 6 (2005) 303-313
29. Hajoui O., Zheng H., Guay J., Letuve S., Fawaz L.M., and Mazer B.D. Regulation of IL-13 receptor α1 expression and signaling on human tonsillar B-lymphocyte subsets. J Allergy Clin Immunol (2007) Aug 28 [epub ahead of print]
30. Defrance T., Carayon P., Billian G., Guillemot J.C., Minty A., Caput D., et al. Interleukin 13 is a B cell stimulating factor. J Exp Med 179 (1994) 135-143
31. Gounni A.S., Hamid Q., Rahman S.M., Hoeck J., Yang J., and Shan L. IL-9-mediated induction of eotaxin1/CCL11 in human airway smooth muscle cells. J Immunol 173 (2004) 2771-2779
32. Erpenbeck V.J., Hohlfeld J.M., Volkmann B., Hagenberg A., Geldmacher H., Braun A., et al. Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes. J Allergy Clin Immunol 111 (2003) 1319-1327
33. Gounni A.S., Gregory B., Nutku E., Aris F., Latifa K., Minshall E., et al. Interleukin-9 enhances interleukin-5 receptor expression, differentiation, and survival of human eosinophils. Blood 96 (2000) 2163-2171
34. Louahed J., Zhou Y., Maloy W.L., Rani P.U., Weiss C., Tomer Y., et al. Interleukin 9 promotes influx and local maturation of eosinophils. Blood 97 (2001) 1035-1042