Characterization of the equine 2′-5′ oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genes

BMC Genomics

Volumn 8, Issue , 2007, Pages

  Rios, Jonathan J ^a   Perelygin, Andrey A ^b   Long, Maureen T ^c   Lear, Teri L ^d   Zharkikh, Andrey A ^e   Brinton, Margo A ^b   Adelson, David L ^f  

^a TEXAS A AND M UNIVERSITY   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c University of Florida College of Veterinary Medicine   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

^e Myriad Genetic Laboratories   (United States)

^f UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2' 5' OLIGOADENYLATE SYNTHETASE 1; COMPLEMENTARY DNA; DINUCLEOTIDE; RIBONUCLEASE L; SYNTHETASE; UNCLASSIFIED DRUG; 2',5' OLIGOADENYLATE SYNTHETASE; RIBONUCLEASE;

ARTICLE; CHROMOSOMAL LOCALIZATION; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; GENE LIBRARY; GENETIC IDENTIFICATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HORSE; HUMAN; INNATE IMMUNITY; MICROSATELLITE MARKER; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PROTEIN ASSEMBLY; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; BACTERIAL ARTIFICIAL CHROMOSOME; CHROMOSOME MAP; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; SPECIES DIFFERENCE; STOP CODON;

EQUIDAE; MAMMALIA; MURINAE; MUS; WEST NILE VIRUS;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CODON, TERMINATOR; ENDORIBONUCLEASES; HORSES; IMMUNITY, NATURAL; IN SITU HYBRIDIZATION, FLUORESCENCE; SPECIES SPECIFICITY;

EID: 35648984463     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-8-313     Document Type: Article

References (71)

1. Baglioni C Minks MA Maroney PA Interferon action may be mediated by activation of a nuclease by pppA2′p5′A2′p5′A Nature 1978, 273(5664):684-687. 10.1038/273684a0 208001
2. Clemens MJ Williams BR Inhibition of cell-free protein synthesis by pppA2′p5′A2′p5′A: A novel oligonucleotide synthesized by interferon-treated L cell extracts Cell 1978, 13(3):565-572. 10.1016/0092-8674(78)90329-X 657268
3. Kerr IM Brown RE pppA2′p5′A2′p5′A: An inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells Proc Natl Acad Sci USA 1978, 75(1):256-260. 411225 272640 10.1073/pnas.75.1.256
4. Hovanessian AG Brown RE Kerr IM Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells Nature 1977, 268(5620):537-540. 10.1038/268537a0 560630
5. Kerr IM Brown RE Hovanessian AG Nature of inhibitor of cell-free protein synthesis formed in response to interferon and double-stranded RNA Nature 1977, 268(5620):540-542. 10.1038/268540a0 196217
6. Roberts WK Hovanessian A Brown RE Clemens MJ Kerr IM Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis Nature 1976, 264(5585):477-480. 10.1038/264477a0 1004583
7. Castelli JC Hassel BA Maran A Paranjape J Hewitt JA Li XL Hsu YT Silverman RH Youle RJ The role of 2′-5′ oligoadenylate-activated ribonuclease L in apoptosis Cell Death Differ 1998, 5(4):313-320. 10.1038/sj.cdd.4400352 10200477
8. Diaz-Guerra M Rivas C Esteban M Activation of the IFN-inducible enzyme RNase L causes apoptosis of animal cells Virology 1997, 236(2):354-363. 10.1006/viro.1997.8719 9325243
9. Mullan PB Hosey AM Buckley NE Quinn JE Kennedy RD Johnston PG Harkin DP The 2,5 oligoadenylate synthetase/RNaseL pathway is a novel effector of BRCA1- and interferon-gamma-mediated apoptosis Oncogene 2005, 24(35):5492-5501. 10.1038/sj.onc.1208698 15940267
10. Zhou A Paranjape J Brown TL Nie H Naik S Dong B Chang A Trapp B Fairchild R Colmenares C Interferon action and apoptosis are defective in mice devoid of 2′,5′-oligoadenylate-dependent RNase L Embo J 1997 16 21 6355 6363 1170242 9351818 10.1093/emboj/16.21.6355
11. Domingo-Gil E Esteban M Role of mitochondria in apoptosis induced by the 2-5A system and mechanisms involved Apoptosis 2006, 11(5):725-738. 10.1007/s10495-006-5541-0 16532271
12. Perelygin AA Scherbik SV Zhulin IB Stockman BM Li Y Brinton MA Positional cloning of the murine flavivirus resistance gene Proc Natl Acad Sci USA 2002, 99(14):9322-9327. 123139 12080145 10.1073/ pnas.142287799
13. Mashimo T Lucas M Simon-Chazottes D Frenkiel MP Montagutelli X Ceccaldi PE Deubel V Guenet JL Despres P A nonsense mutation in the gene encoding 2′-5′-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice Proc Natl Acad Sci USA 2002, 99(17):11311-11316. 123253 12186974 10.1073/pnas.172195399
14. Hovnanian A Rebouillat D Mattei MG Levy ER Marie I Monaco AP Hovanessian AG The human 2′,5′-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms Genomics 1998, 52(3):267-277. 10.1006/geno.1998.5443 9790745
15. Chebath J Benech P Hovanessian A Galabru J Revel M Four different forms of interferon-induced 2′,5′-oligo(A) synthetase identified by immunoblotting in human cells J Biol Chem 1987, 262(8):3852-3857. 2434505
16. Hovanessian AG Laurent AG Chebath J Galabru J Robert N Svab J Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies Embo J 1987, 6(5):1273-1280. 553929 2440675
17. Merlin G Chebath J Benech P Metz R Revel M Molecular cloning and sequence of partial cDNA for interferon-induced (2′-5′)oligo(A) synthetase mRNA from human cells Proc Natl Acad Sci USA 1983, 80(16):4904-4908 384155 6348777 10.1073/ pnas.80.16.4904
18. Benech P Merlin G Revel M Chebath J 3′ end structure of the human (2′-5′) oligo A synthetase gene: Prediction of two distinct proteins with cell type-specific expression Nucleic acids research 1985, 13(4):1267-1281. 341071 2860635 10.1093/nar/13.4.1267
19. Bonnevie-Nielsen V Field LL Lu S Zheng DJ Li M Martensen PM Nielsen TB Beck-Nielsen H Lau YL Pociot F Variation in antiviral 2′,5′-oligoadenylate synthetase (2′5′AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene Am J Hum Genet 2005, 76(4):623-633. 1199299 15732009 10.1086/429391
20. Yakub I Lillibridge KM Moran A Gonzalez OY Belmont J Gibbs RA Tweardy DJ Single nucleotide polymorphisms in genes for 2′-5′-oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection J Infect Dis 2005, 192(10):1741-1748. 10.1086/497340 16235172
21. Hamano E Hijikata M Itoyama S Quy T Phi NC Long HT Ha le D Ban VV Matsushita I Yanai H Polymorphisms of interferon-inducible genes OAS-1 and MxA associated with SARS in the Vietnamese population Biochem Biophys Res Commun 2005, 329(4):1234-1239. 10.1016/j.bbrc.2005.02.101 15766558
22. He J Feng D de Vlas SJ Wang H Fontanet A Zhang P Plancoulaine S Tang F Zhan L Yang H Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: A case-control study BMC Infect Dis 2006, 6:106. 1550407-16824203 10.1186/1471-2334-6-106
23. Knapp S Yee LJ Frodsham AJ Hennig BJ Hellier S Zhang L Wright M Chiaramonte M Graves M Thomas HC Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: Roles of MxA, OAS-1 and PKR Genes Immun 2003, 4(6):411-419. 10.1038/sj.gene.6363984 12944978
24. Squire J Zhou A Hassel BA Nie H Silverman RH Localization of the interferon-induced, 2-5A-dependent RNase gene (RNS4) to human chromosome 1q25 Genomics 1994, 19(1):174-175. 10.1006/geno.1994.1033 7514564
25. Squire J Meurs EF Chong KL McMillan NA Hovanessian AG Williams BR Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22 Genomics 1993, 16(3):768-770. 10.1006/geno.1993.1263 7686884
26. Zhou A Hassel BA Silverman RH Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action Cell 1993, 72(5):753-765. 10.1016/0092-8674(93)90403-D 7680958
27. Dong B Silverman RH A bipartite model of 2-5A-dependent RNase L J Biol Chem 1997, 272(35):22236-22242. 10.1074/jbc.272.35.22236 9268370
28. Cole JL Carroll SS Kuo LC Stoichiometry of 2′,5′-oligoadenylate-induced dimerization of ribonuclease L. A sedimentation equilibrium study J Biol Chem 1996, 271(8):3979-3981. 10.1074/jbc.271.8.3979 8626728
29. Tanaka N Nakanishi M Kusakabe Y Goto Y Kitade Y Nakamura KT Structural basis for recognition of 2′,5′-linked oligoadenylates by human ribonuclease L Embo J 2004, 23(20):3929-3938. 524351 15385955 10.1038/sj.emboj.7600420
30. Dong B Silverman RH 2-5A-dependent RNase molecules dimerize during activation by 2-5A J Biol Chem 1995, 270(8):4133-4137. 10.1074/ jbc.270.8.4133 7876164
31. Nakanishi M Goto Y Kitade Y 2-5A induces a conformational change in the ankyrin-repeat domain of RNase L Proteins 2005, 60(1):131-138. 10.1002/ prot.20474 15849753
32. Perelygin AA Lear TL Zharkikh AA Brinton MA Structure of equine 2′-5′oligoadenylate synthetase (OAS) gene family and FISH mapping of OAS genes to ECA8p15 - > p14 and BTA17q24 - >q25 Cytogenet Genome Res 2005, 111(1):51-56. 10.1159/000085670 16093721
33. Ewing B Green P Base-calling of automated sequencer traces using phred. II. Error probabilities Genome Res 1998, 8(3):186-194. 9521922
34. Ewing B Hillier L Wendl MC Green P Base-calling of automated sequencer traces using phred. I. Accuracy assessment Genome Res 1998, 8(3):175-185. 9521921
35. Gordon D Viewing and Editing Assembled Sequences Using Consed Current Protocols in Bioinformatics New York: John Wiley & Co Baxevanis AD, Davison DB 2004, 11.12.11-11.12.43.
36. Gordon D Abajian C Green P Consed: A graphical tool for sequence finishing Genome Res 1998, 8(3):195-202. 9521923
37. Laboratory of Phil Green http://www.phrap.org
38. NCBI Trace Archive http://www.ncbi.nlm.nih.gov/Traces/trace.cgi?
39. Chen TM Kuo PL Hsu CH Tsai SJ Chen MJ Lin CW Sun HS Microsatellite in the 3′ untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression Human mutation 2007, 28(1):98 10.1002/humu.9471 17154280
40. Stephens M Scheet P Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation Am J Hum Genet 2005, 76(3):449-462. 1196397 15700229 10.1086/428594
41. Stephens M Smith NJ Donnelly P A new statistical method for haplotype reconstruction from population data Am J Hum Genet 2001, 68(4):978-989. 1275651 11254454 10.1086/319501
42. TIGR Institute for Genomic Research http://compbio.dfci.harvard.edu/tgi/ cgi-bin/tgi/Blast/
43. Pig EST Data Explorer http://pede.dna.affrc.go.jp/
44. UCSC Genome Bioinformatics http://www.genome.ucsc.edu
45. MOTIF Search http://motif.genome.jp/
46. Ramensky V Bork P Sunyaev S Human non-synonymous SNPs: Server and survey Nucleic acids research 2002, 30(17):3894-3900. 137415 12202775 10.1093/ nar/gkf493
47. Sunyaev S Ramensky V Bork P Towards a structural basis of human non-synonymous single nucleotide polymorphisms Trends Genet 2000, 16(5):198-200. 10.1016/S0168-9525(00)01988-0 10782110
48. Sunyaev S Ramensky V Koch I Lathe W 3rd Kondrashov AS Bork P Prediction of deleterious human alleles Human molecular genetics 2001, 10(6):591-597. 10.1093/hmg/10.6.591 11230178
49. Sarkar SN Miyagi M Crabb JW Sen GC Identification of the substrate-binding sites of 2′-5′-oligoadenylate synthetase J Biol Chem 2002, 277(27):24321-24330. 10.1074/jbc.M110202200 11986302
50. Cayley PJ White RF Antoniw JF Walesby NJ Kerr IM Distribution of the ppp(A2′p)nA-binding protein and interferon-related enzymes in animals, plants, and lower organisms Biochem Biophys Res Commun 1982, 108(3):1243-1250. 10.1016/0006-291X(82)92133-7 6185117
51. Perelygin AA Zharkikh AA Scherbik SV Brinton MA The mammalian 2'-5' oligoadenylate synthetase gene family: Evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla J Mol Evol 2006, 63(4):562-576. 10.1007/s00239-006-0073-3 17024523
52. Ensembl http://www.ensembl.org
53. Raudsepp T Fronicke L Scherthan H Gustavsson I Chowdhary BP Zoo-FISH delineates conserved chromosomal segments in horse and man Chromosome Res 1996, 4(3):218-225 10.1007/BF02254963 8793207
54. Nilsson S Helou K Walentinsson A Szpirer C Nerman O Stahl F Rat-mouse and rat-human comparative maps based on gene homology and high-resolution zoo-FISH Genomics 2001, 74(3):287-298. 10.1006/ geno.2001.6550 11414756
55. Breen M Thomas R Binns MM Carter NP Langford CF Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog (Canis familiaris) and human Genomics 1999, 61(2):145-155. 10.1006/geno.1999.5947 10534400
56. Yang F O'Brien PC Milne BS Graphodatsky AS Solanky N Trifonov V Rens W Sargan D Ferguson-Smith MA A complete comparative chromosome map for the dog, red fox, and human and its integration with canine genetic maps Genomics 1999, 62(2):189-202. 10.1006/geno.1999.5989 10610712
57. Solinas-Toldo S Lengauer C Fries R Comparative genome map of human and cattle Genomics 1995, 27(3):489-496. 10.1006/geno.1995.1081 7558031
58. Feng Y Goulet AC Nelson MA Identification and characterization of the human Cdc2l2 gene promoter Gene 2004, 330:75-84. 10.1016/ j.gene.2004.01.006 15087126
59. Ogasawara K Terada T Asaka J Katsura T Inui K Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element J Pharmacol Exp Ther 2006, 319(1):317-322. 10.1124/ jpet.106.108233 16809478
60. Rani CS Qiang M Ticku MK Potential role of cAMP response element-binding protein in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cells Mol Pharmacol 2005, 67(6):2126-2136. 10.1124/mol.104.007872 15774772
61. Patrocles Targets Database http://www.patrocles.org/
62. Frazer KA Pachter L Poliakov A Rubin EM Dubchak I VISTA: Computational tools for comparative genomics Nucleic acids research 2004, 32 (Web Server):W273-279. 441596 15215394 10.1093/nar/gkh458
63. Mayor C Brudno M Schwartz JR Poliakov A Rubin EM Frazer KA Pachter LS Dubchak I VISTA: Visualizing global DNA sequence alignments of arbitrary length Bioinformatics (Oxford, England) 2000, 16(11):1046-1047. 10.1093/ bioinformatics/16.11.1046 11159318
64. Lindblad-Toh K Plant & Animal Genome XV: January 13-17, 2007 2007 San Diego, California, USA 2007
65. Lindblad-Toh K Wade CM Mikkelsen TS Karlsson EK Jaffe DB Kamal M Clamp M Chang JL Kulbokas EJ 3rd Zody MC Genome sequence, comparative analysis and haplotype structure of the domestic dog Nature 2005, 438(7069):803-819. 10.1038/nature04338 16341006
66. Sharma VK Kumar N Brahmachari SK Ramachandran S Abundance of Dinucleotide Repeats and Gene Expression are Inversely Correlated: A role for gene function in addition to intron length Physiol Genomics 2007.
67. Perelygin AA Lear TL Zharkikh AA Brinton MA Comparative analysis of vertebrate EIF2AK2 (PKR) genes and assignment of the equine gene to ECA15q24-q25 and the bovine gene to BTA11q12-q15 Genet Sel Evol 2006, 38(5):551-563. 10.1051/gse:2006021 16954046
68. Bowling AT Breen M Chowdhary BP Hirota K Lear T Millon LV Ponce de Leon FA Raudsepp T Stranzinger G International system for cytogenetic nomenclature of the domestic horse. Report of the Third International Committee for the Standardization of the domestic horse karyotype, Davis, CA, USA, 1996 Chromosome Res 1997, 5:433-443. 10.1023/ A:1018408811881 9421259
69. Altschul SF Gish W Miller W Myers EW Lipman DJ Basic local alignment search tool J Mol Biol 1990, 215(3):403-410. 2231712
70. Altschul SF Madden TL Schaffer AA Zhang J Zhang Z Miller W Lipman DJ Gapped BLAST and PSI-BLAST: A new generation of protein database search programs Nucleic acids research 1997, 25(17):3389-3402. 146917 9254694 10.1093/nar/25.17.3389
71. National Center for Biotechnology Information http://www.ncbi.nlm.nih.gov/