Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia

Neuroscience Research

Volumn 59, Issue 4, 2007, Pages 406-412

  Ishikawa, Akira ^a   Yoshida, Hidemi ^a   Metoki, Norifumi ^b   Toki, Tsutomu ^a   Imaizumi, Tadaatsu ^a   Matsumiya, Tomoh ^a   Yamashita, Koji ^c   Taima, Kageaki ^a   Satoh, Kei ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b Hirosaki Stroke Center   (Japan)

^c AOMORI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Astroglia; Cerebral edema; Edaravone; HIF 1; Stroke; VEGF

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; NORPHENAZONE; VASCULOTROPIN;

ARTICLE; ASTROCYTE; BRAIN EDEMA; CELL HYPOXIA; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HYPOXIC CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; WESTERN BLOTTING;

ANTIPYRINE; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN EDEMA; CELL NUCLEUS; CELLS, CULTURED; CEREBRAL ARTERIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; HUMANS; HYPOXIA, BRAIN; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 35549012820     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.08.008     Document Type: Article

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