-
1
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist C.J., and Kastan M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421 (2003) 499-506
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
2
-
-
23844433614
-
Molecular basis of ataxia telangiectasia and related diseases
-
Ball L.G., and Xiao W. Molecular basis of ataxia telangiectasia and related diseases. Acta. Pharmacol. Sin. 26 (2005) 897-907
-
(2005)
Acta. Pharmacol. Sin.
, vol.26
, pp. 897-907
-
-
Ball, L.G.1
Xiao, W.2
-
3
-
-
15844426692
-
Atm-deficient mice: a paradigm of ataxia telangiectasia
-
Barlow C., Hirotsune S., Paylor R., Liyanage M., Eckhaus M., Collins F., Shiloh Y., Crawley J.N., Ried T., Tagle D., and Wynshaw-Boris A. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86 (1996) 159-171
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
Shiloh, Y.7
Crawley, J.N.8
Ried, T.9
Tagle, D.10
Wynshaw-Boris, A.11
-
4
-
-
25144451864
-
Analysis of full length ADAMTS6 transcript reveals alternative splicing and a role for the 5′ untranslated region in translational control
-
Bevitt D.J., Li Z., Lindrop J.L., Barker M.D., Clarke M.P., and McKie N. Analysis of full length ADAMTS6 transcript reveals alternative splicing and a role for the 5′ untranslated region in translational control. Gene 359 (2005) 99-110
-
(2005)
Gene
, vol.359
, pp. 99-110
-
-
Bevitt, D.J.1
Li, Z.2
Lindrop, J.L.3
Barker, M.D.4
Clarke, M.P.5
McKie, N.6
-
5
-
-
0029807481
-
A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies
-
Byrd P.J., Cooper P.R., Stankovic T., Kullar H.S., Watts G.D., Robinson P.J., and Taylor M.R. A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies. Hum. Mol. Genet. 5 (1996) 1785-1791
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1785-1791
-
-
Byrd, P.J.1
Cooper, P.R.2
Stankovic, T.3
Kullar, H.S.4
Watts, G.D.5
Robinson, P.J.6
Taylor, M.R.7
-
6
-
-
0036534129
-
Alternative splicing: multiple control mechanisms and involvement in human disease
-
Caceres J.F., and Kornblihtt A.R. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet. 18 (2002) 186-193
-
(2002)
Trends Genet.
, vol.18
, pp. 186-193
-
-
Caceres, J.F.1
Kornblihtt, A.R.2
-
7
-
-
0030476720
-
The product of the ATM gene is a 370-kDa nuclear phosphoprotein
-
Chen G., and Lee E. The product of the ATM gene is a 370-kDa nuclear phosphoprotein. J. Biol. Chem. 271 (1996) 33693-33697
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 33693-33697
-
-
Chen, G.1
Lee, E.2
-
8
-
-
26944478233
-
Evolutionary conservation suggests a regulatory function of AUG triplets in 5′-UTRs of eukaryotic genes
-
Churbanov A., Rogozin I.B., Babenko V.N., Ali H., and Koonin E.V. Evolutionary conservation suggests a regulatory function of AUG triplets in 5′-UTRs of eukaryotic genes. Nucleic Acids Res. 33 (2005) 5512-5520
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5512-5520
-
-
Churbanov, A.1
Rogozin, I.B.2
Babenko, V.N.3
Ali, H.4
Koonin, E.V.5
-
9
-
-
0029848286
-
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice
-
Elson A., Wang Y., Daugherty C.J., Morton C.C., Zhou F., Campos-Torres J., and Leder P. Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 13084-13089
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 13084-13089
-
-
Elson, A.1
Wang, Y.2
Daugherty, C.J.3
Morton, C.C.4
Zhou, F.5
Campos-Torres, J.6
Leder, P.7
-
10
-
-
0031978181
-
Base-calling of automated sequencer traces using phred. II. Error probabilities
-
Ewing B., and Green P. Base-calling of automated sequencer traces using phred. II. Error probabilities. Genome Res. 8 (1998) 186-194
-
(1998)
Genome Res.
, vol.8
, pp. 186-194
-
-
Ewing, B.1
Green, P.2
-
11
-
-
0035105888
-
Rapid radiation-induction of ATM protein levels in situ
-
Fang Z.M., Lee C.S., Sarris M., Kearsley J.H., Murrell D., Lavin M.F., Keating K., and Clarke R.A. Rapid radiation-induction of ATM protein levels in situ. Pathology 33 (2001) 30-36
-
(2001)
Pathology
, vol.33
, pp. 30-36
-
-
Fang, Z.M.1
Lee, C.S.2
Sarris, M.3
Kearsley, J.H.4
Murrell, D.5
Lavin, M.F.6
Keating, K.7
Clarke, R.A.8
-
12
-
-
0035007832
-
A porcine BAC library with tenfold genome coverage: a resource for physical and genetic map integration
-
Fahrenkrug S.C., Rohrer G.A., Freking B.A., Smith T.P.L., Osoegawa K., Shu C.L., Catanese J.J., and de Jong P.J. A porcine BAC library with tenfold genome coverage: a resource for physical and genetic map integration. Mamm. Genome 12 (2001) 472-474
-
(2001)
Mamm. Genome
, vol.12
, pp. 472-474
-
-
Fahrenkrug, S.C.1
Rohrer, G.A.2
Freking, B.A.3
Smith, T.P.L.4
Osoegawa, K.5
Shu, C.L.6
Catanese, J.J.7
de Jong, P.J.8
-
13
-
-
13344269672
-
Predominance of null mutations in ataxia-telangiectasia
-
Gilad S., Khosravi R., Shkedy D., Uziel T., Ziv Y., Savitsky K., Rotman G., Smith S., Chessa L., Jorgensen T.J., Harnik R., Frydman M., Sanal O., Portnoi S., Goldwicz Z., Jaspers N.G., Gatti R.A., Lenoir G., Lavin M.F., Tatsumi K., Wegner R.D., Shiloh Y., and Bar-Shira A. Predominance of null mutations in ataxia-telangiectasia. Hum. Mol. Genet. 5 (1996) 433-439
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 433-439
-
-
Gilad, S.1
Khosravi, R.2
Shkedy, D.3
Uziel, T.4
Ziv, Y.5
Savitsky, K.6
Rotman, G.7
Smith, S.8
Chessa, L.9
Jorgensen, T.J.10
Harnik, R.11
Frydman, M.12
Sanal, O.13
Portnoi, S.14
Goldwicz, Z.15
Jaspers, N.G.16
Gatti, R.A.17
Lenoir, G.18
Lavin, M.F.19
Tatsumi, K.20
Wegner, R.D.21
Shiloh, Y.22
Bar-Shira, A.23
more..
-
14
-
-
0035252410
-
Alternative splicing: increasing diversity in the proteomic world
-
Graveley B.R. Alternative splicing: increasing diversity in the proteomic world. Trends Genet. 17 (2001) 100-107
-
(2001)
Trends Genet.
, vol.17
, pp. 100-107
-
-
Graveley, B.R.1
-
15
-
-
0041332880
-
Site-directed mutagenesis of the ATM promoter: consequences for response to proliferation and ionizing radiation
-
Gueven N., Keating K., Fukao T., Loeffler H., Kondo N., Rodemann H.P., and Lavin M.F. Site-directed mutagenesis of the ATM promoter: consequences for response to proliferation and ionizing radiation. Genes, Chromosomes Cancer 38 (2003) 157-167
-
(2003)
Genes, Chromosomes Cancer
, vol.38
, pp. 157-167
-
-
Gueven, N.1
Keating, K.2
Fukao, T.3
Loeffler, H.4
Kondo, N.5
Rodemann, H.P.6
Lavin, M.F.7
-
16
-
-
33644932202
-
Regulation of the Atm promoter in vivo
-
Gueven N., Fukao T., Luff J., Paterson C., Kay G., Kondo N., and Lavin M.F. Regulation of the Atm promoter in vivo. Genes, Chromosomes Cancer 45 (2006) 61-71
-
(2006)
Genes, Chromosomes Cancer
, vol.45
, pp. 61-71
-
-
Gueven, N.1
Fukao, T.2
Luff, J.3
Paterson, C.4
Kay, G.5
Kondo, N.6
Lavin, M.F.7
-
17
-
-
0032524070
-
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
-
Herzog K.H., Chong M.J., Kapsetaki M., Morgan J.I., and McKinnon P.J. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 280 (1998) 1089-1091
-
(1998)
Science
, vol.280
, pp. 1089-1091
-
-
Herzog, K.H.1
Chong, M.J.2
Kapsetaki, M.3
Morgan, J.I.4
McKinnon, P.J.5
-
18
-
-
0347623371
-
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
-
Johnson J.M., Castle J., Garrett-Engele P., Kan Z., Loerch P.M., Armour C.D., Santos R., Schadt E.E., Stoughton R., and Shoemaker D.D. Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science 302 (2003) 2141-2144
-
(2003)
Science
, vol.302
, pp. 2141-2144
-
-
Johnson, J.M.1
Castle, J.2
Garrett-Engele, P.3
Kan, Z.4
Loerch, P.M.5
Armour, C.D.6
Santos, R.7
Schadt, E.E.8
Stoughton, R.9
Shoemaker, D.D.10
-
20
-
-
0036510540
-
A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells
-
Kishi S., and Lu K.P. A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells. J. Biol. Chem. 277 (2002) 7420-7429
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7420-7429
-
-
Kishi, S.1
Lu, K.P.2
-
21
-
-
0005218668
-
Influences of mRNA secondary structure on initiation by eukaryotic ribosomes
-
Kozak M. Influences of mRNA secondary structure on initiation by eukaryotic ribosomes. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 2850-2854
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 2850-2854
-
-
Kozak, M.1
-
22
-
-
27144555357
-
Regulation of translation via mRNA structure in prokaryotes and eukaryotes
-
Kozak M. Regulation of translation via mRNA structure in prokaryotes and eukaryotes. Gene 361 (2005) 13-37
-
(2005)
Gene
, vol.361
, pp. 13-37
-
-
Kozak, M.1
-
23
-
-
0030472725
-
Analysis of the ATM protein in wild-type and ataxia telangiectasia cells
-
Lakin N.D., Weber P., Stankovic T., Rottinghaus S.T., Taylor A.M., and Jackson S.P. Analysis of the ATM protein in wild-type and ataxia telangiectasia cells. Oncogene 13 (1996) 2707-2716
-
(1996)
Oncogene
, vol.13
, pp. 2707-2716
-
-
Lakin, N.D.1
Weber, P.2
Stankovic, T.3
Rottinghaus, S.T.4
Taylor, A.M.5
Jackson, S.P.6
-
24
-
-
0030933152
-
The genetic defect in ataxia-telangiectasia
-
Lavin M.F., and Shiloh Y. The genetic defect in ataxia-telangiectasia. Annu. Rev. Immunol. 15 (1997) 177-202
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 177-202
-
-
Lavin, M.F.1
Shiloh, Y.2
-
25
-
-
3242879267
-
Functional consequences of sequence alterations in the ATM gene
-
Lavin M.F., Scott S., Gueven N., Kozlov S., Peng C., and Chen P. Functional consequences of sequence alterations in the ATM gene. DNA Repair (Amst). 3 (2004) 1197-1205
-
(2004)
DNA Repair (Amst).
, vol.3
, pp. 1197-1205
-
-
Lavin, M.F.1
Scott, S.2
Gueven, N.3
Kozlov, S.4
Peng, C.5
Chen, P.6
-
26
-
-
35548930304
-
-
Pearson Education, Inc., New Jersey (USA)
-
Lewin B. GenesVIII (2004), Pearson Education, Inc., New Jersey (USA) 597-631
-
(2004)
GenesVIII
, pp. 597-631
-
-
Lewin, B.1
-
27
-
-
4444339751
-
ATM and ataxia telangiectasia
-
McKinnon P.J. ATM and ataxia telangiectasia. EMBO Rep. 5 (2004) 772-776
-
(2004)
EMBO Rep.
, vol.5
, pp. 772-776
-
-
McKinnon, P.J.1
-
28
-
-
0038617729
-
Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss
-
Modrek C.J., and Lee C.J. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat. Genet. 34 (2003) 177-180
-
(2003)
Nat. Genet.
, vol.34
, pp. 177-180
-
-
Modrek, C.J.1
Lee, C.J.2
-
29
-
-
10944245056
-
Alternative splicing of conserved exons is frequently species-specific in human and mouse
-
Pan Q., Bakowski M.A., Morris Q., Zhang W., Frey B.J., Hughes T.R., and Blencowe B.J. Alternative splicing of conserved exons is frequently species-specific in human and mouse. Trends Genet. 21 (2005) 73-77
-
(2005)
Trends Genet.
, vol.21
, pp. 73-77
-
-
Pan, Q.1
Bakowski, M.A.2
Morris, Q.3
Zhang, W.4
Frey, B.J.5
Hughes, T.R.6
Blencowe, B.J.7
-
30
-
-
0037148403
-
ATM function and telomere stability
-
Pandita T.K. ATM function and telomere stability. Oncogene 21 (2002) 611-618
-
(2002)
Oncogene
, vol.21
, pp. 611-618
-
-
Pandita, T.K.1
-
31
-
-
0033000784
-
Atm inactivation results in aberrant telomere clustering during meiotic prophase
-
Pandita T.K., Westphal C.H., Anger M., Sawant S.G., Geard C.R., Pandita R.K., and Scherthan H. Atm inactivation results in aberrant telomere clustering during meiotic prophase. Mol. Cell Biol. 19 (1999) 5096-5105
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 5096-5105
-
-
Pandita, T.K.1
Westphal, C.H.2
Anger, M.3
Sawant, S.G.4
Geard, C.R.5
Pandita, R.K.6
Scherthan, H.7
-
32
-
-
0034624782
-
Ionizing radiation activates the ATM kinase throughout the cell cycle
-
Pandita T.K., Lieberman H.B., Lim D.S., Dhar S., Zheng W., Taya Y., and Kastan M.B. Ionizing radiation activates the ATM kinase throughout the cell cycle. Oncogene 19 (2000) 1386-1391
-
(2000)
Oncogene
, vol.19
, pp. 1386-1391
-
-
Pandita, T.K.1
Lieberman, H.B.2
Lim, D.S.3
Dhar, S.4
Zheng, W.5
Taya, Y.6
Kastan, M.B.7
-
33
-
-
0030816212
-
Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene
-
Platzer M., Rotman G., Bauer D., Uziel T., Savitsky K., Bar-Shira A., Gilad S., Shiloh Y., and Rosenthal A. Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene. Genome Res. 7 (1997) 592-605
-
(1997)
Genome Res.
, vol.7
, pp. 592-605
-
-
Platzer, M.1
Rotman, G.2
Bauer, D.3
Uziel, T.4
Savitsky, K.5
Bar-Shira, A.6
Gilad, S.7
Shiloh, Y.8
Rosenthal, A.9
-
34
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky K., Bar-Shira A., Gilad S., Rotman G., Ziv Y., Vanagaite L., Tagle D.A., Smith S., Uziel T., and Sfez S. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268 (1995) 1749-1753
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
Tagle, D.A.7
Smith, S.8
Uziel, T.9
Sfez, S.10
-
35
-
-
0030871226
-
Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression
-
Savitsky K., Platzer M., Uziel T., Gilad S., Sartiel A., Rosenthal A., Elroy-Stein O., Shiloh Y., and Rotman G. Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression. Nucleic Acids Res. 25 (1997) 1678-1684
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1678-1684
-
-
Savitsky, K.1
Platzer, M.2
Uziel, T.3
Gilad, S.4
Sartiel, A.5
Rosenthal, A.6
Elroy-Stein, O.7
Shiloh, Y.8
Rotman, G.9
-
36
-
-
27844583947
-
Swine in biomedical research: creating the building blocks of animal models
-
Schook L., Beattie C., Beever J., Donovan S., Jamison R., Niemi S., Rothschild M., Rutherford M., Smith D., and Zuckerman F. Swine in biomedical research: creating the building blocks of animal models. Anim. Biotechnol. 16 (2005) 183-190
-
(2005)
Anim. Biotechnol.
, vol.16
, pp. 183-190
-
-
Schook, L.1
Beattie, C.2
Beever, J.3
Donovan, S.4
Jamison, R.5
Niemi, S.6
Rothschild, M.7
Rutherford, M.8
Smith, D.9
Zuckerman, F.10
-
37
-
-
0037365789
-
ATM and related protein kinases: safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3 (2003) 155-168
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
38
-
-
0035839431
-
Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T → G mutations, showing a less severe phenotype
-
Stewart G.S., Last J.I., Stankovic T., Haites N., Kidd A.M., Byrd P.J., and Taylor A.M. Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T → G mutations, showing a less severe phenotype. J. Biol. Chem. 276 (2001) 30133-30141
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30133-30141
-
-
Stewart, G.S.1
Last, J.I.2
Stankovic, T.3
Haites, N.4
Kidd, A.M.5
Byrd, P.J.6
Taylor, A.M.7
-
40
-
-
0035939844
-
Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53
-
Turenne G.A., Paul P., Laflair L., and Price B.D. Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53. Oncogene 20 (2001) 5100-5110
-
(2001)
Oncogene
, vol.20
, pp. 5100-5110
-
-
Turenne, G.A.1
Paul, P.2
Laflair, L.3
Price, B.D.4
-
41
-
-
1042292696
-
ATM and ATR: sensing DNA damage
-
Yang J., Xu Z.P., Huang Y., Hamrick H.E., Duerksen-Hughes P.J., and Yu Y.N. ATM and ATR: sensing DNA damage. World J. Gastroenterol. 10 (2004) 155-160
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 155-160
-
-
Yang, J.1
Xu, Z.P.2
Huang, Y.3
Hamrick, H.E.4
Duerksen-Hughes, P.J.5
Yu, Y.N.6
-
42
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31 (2003) 3406-3415
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
|