Rapid radiation-induction of ATM protein levels in situ

Pathology

Volumn 33, Issue 1, 2001, Pages 30-36

  Fang, Z M ^a   Lee, C S ^a   Sarris, M ^a   Kearsley, J H ^a   Murrell, D ^a,b   Lavin, M F ^b   Keating, K ^b   Clarke, R A ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Ataxia telangiectasia; ATM; Cancer; Protein level; Protein regulation; Radiation induction; Radio protection; Radiosensitivity

Indexed keywords

ATM PROTEIN; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL TYPE; CONTROLLED STUDY; ENZYME ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IONIZING RADIATION; LYMPHOBLASTOID CELL; NORMAL HUMAN; PROTEIN EXPRESSION; PROTEIN PROCESSING; RADIATION PROTECTION; RADIOSENSITIVITY; SKIN; WESTERN BLOTTING;

EID: 0035105888     PISSN: 00313025     EISSN: None     Source Type: Journal    
DOI: 10.1080/00313020125667     Document Type: Article

References (36)

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6. Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation
7. The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
8. Predominance of null mutations in ataxia-telangiectasia
9. Ataxia-telangiectasia: Mutations in ATM cDNA detected by protein-truncation screening
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11. ATM gene product phosphorylates I kappa B-alpha
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13. Interaction between ATM protein and c-Abl in response to DNA damage
14. ATM associates with and phosphorylates p53: Mapping the region of interaction
15. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
16. Requirement of ATM-dependent phosphorylation of brcal in the DNA damage response to doublestrand breaks
17. Upregulation of ATM in sclerosing adenosis of the breast
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24. Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms
25. Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype
26. ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells
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28. Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia
29. Signal transduction. Three paths to stress relief
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31. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
32. Characterization of the signal transduction pathway mediating gamma ray-induced inhibition of DNA synthesis in human cells: Indirect evidence for involvement of calmodulin but not protein kinase C nor p53
33. Localization of a portion of extranuclear ATM to peroxisomes
34. ATM binds to beta-adaptin in cytoplasmic vesicles
35. Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development
36. ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation