Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 37, 2007, Pages 14634-14639

  Stagno, Jason ^a   Aphasizheva, Inna ^b   Aphasizhev, Ruslan ^b   Luecke, Hartmut ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Crystal structure; Nucleotidyl transferase; RNA editing; Terminal RNA uridylyltransferase poly(A) polymerase; Trypanosoma

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HEXOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; NUCLEOSIDE; NUCLEOSIDE TRIPHOSPHATASE; NUCLEOTIDYLTRANSFERASE; PROTEIN TBTUT4; PURINE; PYRIMIDINE; RNA; UNCLASSIFIED DRUG; URACIL; URIDINE PHOSPHATE; URIDINE TRIPHOSPHATE;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME MECHANISM; ENZYME SUBSTRATE; METAL BINDING; NONHUMAN; ORIENTATION; PRIORITY JOURNAL; TRYPANOSOMA;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYTIDINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE; KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RNA; RNA EDITING; RNA NUCLEOTIDYLTRANSFERASES; SUBSTRATE SPECIFICITY; TRYPANOSOMA BRUCEI BRUCEI; URIDINE MONOPHOSPHATE; URIDINE TRIPHOSPHATE;

TRYPANOSOMA;

EID: 35548937853     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0704259104     Document Type: Article

References (34)

1. Aphasizhev R (2005) Cell Mol Life Sci 62:2194-2203.
2. Holm L, Sander C (1995) Trends Biochem Sci 20:345-347.
3. Aravind L, Koonin EV (1999) Nucleic Acids Res 27:1609-1618.
4. Aphasizhev R, Sbicego S, Peris M, Jang SH, Aphasizheva I, Simpson AM, Rivlin A, Simpson L (2002) Cell 108:637-648.
5. Aphasizhev R, Aphasizheva I, Simpson L (2003) Proc Natl Acad Sci USA 100:10617-10622.
6. Ernst NL, Panicucci B, Igo RP, Jr, Panigrahi AK, Salavati R, Stuart K (2003) Mol Cell 11:1525-1536.
7. Aphasizhev R, Aphasizheva I, Simpson L (2004) FEBS Lett 572:15-18.
8. Stagno J, Aphasizheva I, Rosengarth A, Luecke H, Aphasizhev R (2007) J Mol Biol 366:882-899.
9. Trippe R, Guschina E, Hossbach M, Urlaub H, Luhrmann R, Benecke BJ (2006) RNA 12:1494-1504.
10. Rissland OS, Mikulaslova A, Norbury CJ (2007) Mol Cell Biol 27:3612-3624.
11. Read RL, Martinho RG, Wang SW, Carr AM, Norbury CJ (2002) Proc Natl Acad Sci USA 99:12079-12084.
12. Wang L, Eckmann CR, Kadyk LC, Wickens M, Kimble J (2002) Nature 419:312-316.
13. Kwak JE, Wickens M (2007) RNA 13:860-867.
14. Deng J, Ernst NL, Turley S, Stuart KD, Hol WG (2005) EMBO J 24:4007-4017.
15. Rogozin IB, Aravind L, Koonin EV (2003) J Mol Biol 326:1449-1461.
16. Stevenson AL, Norbury CJ (2006) Yeast 23:991-1000.
17. Steitz TA (1997) Harvey Lect 93:75-93.
18. Kwak JE, Wang L, Ballantyne S, Kimble J, Wickens M (2004) Proc Natl Acad Sci USA 101:4407-4412.
19. LaCava J, Houseley J, Saveanu C, Petfalski E, Thompson E, Jacquier A, Tollervey D (2005) Cell 121:713-724.
20. Vanacova S, Wolf J, Martin G, Blank D, Dettwiler S, Friedlein A, Langen H, Keith G, Keller W (2005) PLoS Biol 3:e189.
21. Wyers F, Rougemaille M, Badis G, Rousselle JC, Dufour ME, Boulay J, Regnault B, Devaux F, Namane A, Seraphin B, et al. (2005) Cell 121:725-737.
22. Saitoh S, Chabes A, McDonald WH, Thelander L, Yates JR, Russell P (2002) Cell 109:563-573.
23. Aphasizheva I, Aphasizhev R, Simpson L (2004) J Biol Chem 279:24123-24130.
24. Steitz TA (1999) J Biol Chem 274:17395-17398.
25. Stuart KD, Schnaufer A, Ernst NL, Panigrahi AK (2005) Trends Biochem Sci 30:97-105.
26. Xiong Y, Steitz TA (2004) Nature 430:640-645.
27. Bard J, Zhelkovsky AM, Helmling S, Earnest TN, Moore CL, Bohm A (2000) Science 289:1346-1349.
28. Martin G, Keller W, Doublie S (2000) EMBO J 19:4193-4203.
29. Martin G, Moglich A, Keller W, Doublie S (2004) J Mol Biol 341:911-925.
30. Zhelkovsky A, Helmling S, Bohm A, Moore C (2004) RNA 10:558-564.
31. Moure CM, Bowman BR, Gershon PD, Quiocho FA (2006) Mol Cell 22:339-349.
32. Pflugrath JW (1999) Acta Crystallogr D 55:1718-1725.
33. Emsley P, Cowtan K (2004) Acta Crystallogr D 60:2126-2132.
34. Potterton L, McNicholas S, Krissinel E, Gruber J, Cowtan K, Emsley P, Murshudov GN, Cohen S, Perrakis A, Noble M (2004) Acta Crystallogr D 60:2288-2294.