Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase

Journal of Molecular Biology

Volumn 341, Issue 4, 2004, Pages 911-925

  Martin, Georges ^a   Möglich, Andreas ^a   Keller, Walter ^a   Doublié, Sylvie ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

ATP binding; mRNA 3 end processing; nucleotidyl transferase; poly(A) polymerase; substrate specificity

Indexed keywords

ADENINE; ADENOSINE TRIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA; FUNGAL ENZYME; MAGNESIUM ION; METAL; POLYNUCLEOTIDE ADENYLYLTRANSFERASE;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOCHEMISTRY; CATALYSIS; CATTLE; CONFORMATION; CRYSTAL STRUCTURE; HYDROLYSIS; KINETICS; MAMMAL; MUTATIONAL ANALYSIS; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; STEADY STATE; YEAST;

BOVINAE; EUKARYOTA; MAMMALIA;

EID: 3843067711     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.06.047     Document Type: Article

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