-
1
-
-
6344284357
-
-
Zaag-Loonen van der HJ, Casparie M, Taminiau JAJM, Escher JC, Pereira RR, Derkx HH. The incidence of pediatric inflammatory bowel disease in the Netherlands: 1999-2001. J Pediatr Gastroenterol Nutr. 2004;38:302-307.
-
Zaag-Loonen van der HJ, Casparie M, Taminiau JAJM, Escher JC, Pereira RR, Derkx HH. The incidence of pediatric inflammatory bowel disease in the Netherlands: 1999-2001. J Pediatr Gastroenterol Nutr. 2004;38:302-307.
-
-
-
-
2
-
-
33645684568
-
Incidence of pediatric inflammatory bowel disease in South Wales
-
Ahmed M, Davies IH, Hood K, Jenkins HR. Incidence of pediatric inflammatory bowel disease in South Wales. Arch Dis Child. 2006;91:344-345.
-
(2006)
Arch Dis Child
, vol.91
, pp. 344-345
-
-
Ahmed, M.1
Davies, I.H.2
Hood, K.3
Jenkins, H.R.4
-
3
-
-
0035820318
-
Prospective survey of childhood inflammatory bowel disease in the British isles
-
Sawczenko A, Sandhu BK, Logan RFA, et al. Prospective survey of childhood inflammatory bowel disease in the British isles. Lancet. 2001;357:1093-1094.
-
(2001)
Lancet
, vol.357
, pp. 1093-1094
-
-
Sawczenko, A.1
Sandhu, B.K.2
Logan, R.F.A.3
-
4
-
-
0035897904
-
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
-
Hampe J, Cuthbert A, Croucher PJP, et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet. 2003;362:1925-1928.
-
(2003)
Lancet
, vol.362
, pp. 1925-1928
-
-
Hampe, J.1
Cuthbert, A.2
Croucher, P.J.P.3
-
5
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 2001;411:599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
6
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohora N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 2001;411:603-606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohora, N.3
-
7
-
-
0036202336
-
The molecular classification of the clinical manifestations of Crohn's disease
-
Ahmad T, Armuzzi A, Bunce M, et al. The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology. 2002;122:854-866.
-
(2002)
Gastroenterology
, vol.122
, pp. 854-866
-
-
Ahmad, T.1
Armuzzi, A.2
Bunce, M.3
-
8
-
-
0036202885
-
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
-
Cuthbert AP, Fisher SA, Mirza MM, et al. The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. Gastroenterology. 2002;122:867-874.
-
(2002)
Gastroenterology
, vol.122
, pp. 867-874
-
-
Cuthbert, A.P.1
Fisher, S.A.2
Mirza, M.M.3
-
9
-
-
0037062228
-
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: A cohort study
-
Hampe J, Grebe J, Nikolaus S, et al. Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study. Lancet. 2002;359:1661-1665.
-
(2002)
Lancet
, vol.359
, pp. 1661-1665
-
-
Hampe, J.1
Grebe, J.2
Nikolaus, S.3
-
10
-
-
0036201577
-
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
-
Lesage S, Zouali H, Cezard JP, et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet. 2002;70:845-857.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 845-857
-
-
Lesage, S.1
Zouali, H.2
Cezard, J.P.3
-
11
-
-
0036080129
-
The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease
-
Radlmayr M, Torok HP, Martin K, Folwaczny C. The c-insertion mutation of the NOD2 gene is associated with fistulizing and fibrostenotic phenotypes in Crohn's disease. Gastroenterology. 2002;122:2091-2092.
-
(2002)
Gastroenterology
, vol.122
, pp. 2091-2092
-
-
Radlmayr, M.1
Torok, H.P.2
Martin, K.3
Folwaczny, C.4
-
12
-
-
33646020997
-
New genes in inflammatory bowel disease: Lessons for complex diseases?
-
Gaya DR, Russell RK, Nimmo ER, Satsangi J. New genes in inflammatory bowel disease: lessons for complex diseases? Lancet. 2006;367:1271-1284.
-
(2006)
Lancet
, vol.367
, pp. 1271-1284
-
-
Gaya, D.R.1
Russell, R.K.2
Nimmo, E.R.3
Satsangi, J.4
-
13
-
-
0036245610
-
CARD15 gene and the classification of Crohn's disease
-
Murillo L, Crusius JB, van Bodegraven AA, Alizadeh BZ, Pena AS. CARD15 gene and the classification of Crohn's disease. Immunogenetics. 2002;54:59-61.
-
(2002)
Immunogenetics
, vol.54
, pp. 59-61
-
-
Murillo, L.1
Crusius, J.B.2
van Bodegraven, A.A.3
Alizadeh, B.Z.4
Pena, A.S.5
-
14
-
-
20444467612
-
Association between Toll-like receptor 4 and Inflammatory Bowel Disease
-
Oostenbrug LE, Drenth JPH, de Jong DJ, et al. Association between Toll-like receptor 4 and Inflammatory Bowel Disease. Inflamm Bowel Dis. 2005;11:567-575.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 567-575
-
-
Oostenbrug, L.E.1
Drenth, J.P.H.2
de Jong, D.J.3
-
15
-
-
3042521641
-
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
-
Franchimont D, Vermeire S, El Housni H, et al. Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut. 2004;53:987-992.
-
(2004)
Gut
, vol.53
, pp. 987-992
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
-
16
-
-
2942689466
-
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: Association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis
-
Török H-P, Glas J, Tonenchi L, Mussack T, Folwaczny C. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin Immunol. 2004;112:85-91.
-
(2004)
Clin Immunol
, vol.112
, pp. 85-91
-
-
Török, H.-P.1
Glas, J.2
Tonenchi, L.3
Mussack, T.4
Folwaczny, C.5
-
17
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux JD, Silverberg MS, Daly MJ, et al. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet. 2000;66:1863-1870.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1863-1870
-
-
Rioux, J.D.1
Silverberg, M.S.2
Daly, M.J.3
-
18
-
-
0034785352
-
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
-
Rioux JD, Daly MJ, Silverberg MS, et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat Genet. 2001;29:223-228.
-
(2001)
Nat Genet
, vol.29
, pp. 223-228
-
-
Rioux, J.D.1
Daly, M.J.2
Silverberg, M.S.3
-
19
-
-
0037622913
-
Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31
-
Armuzzi A, Ahmad T, Ling KL, et al. Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31. Gut. 2003;52:1133-1139.
-
(2003)
Gut
, vol.52
, pp. 1133-1139
-
-
Armuzzi, A.1
Ahmad, T.2
Ling, K.L.3
-
20
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova VD, Wintle RF, Rubin LA, et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genet. 2004;36:471-475.
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
-
21
-
-
14944356373
-
A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease
-
Newman B, Gu X, Wintle R, et al. A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease. Gastroenterology. 2005;128:260-269.
-
(2005)
Gastroenterology
, vol.128
, pp. 260-269
-
-
Newman, B.1
Gu, X.2
Wintle, R.3
-
22
-
-
28844459843
-
Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD
-
Vermeire S, Pierik M, Hlavaty T, et al. Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD. Gastroenterology. 2005;129:1845-1853.
-
(2005)
Gastroenterology
, vol.129
, pp. 1845-1853
-
-
Vermeire, S.1
Pierik, M.2
Hlavaty, T.3
-
23
-
-
28844509940
-
The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease
-
Noble CL, Nimmo ER, Drummond H, et al. The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease. Gastroenterology. 2005;129:1854-1864.
-
(2005)
Gastroenterology
, vol.129
, pp. 1854-1864
-
-
Noble, C.L.1
Nimmo, E.R.2
Drummond, H.3
-
24
-
-
2442519456
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
-
Stoll M, Corneliussen B, Costello CM, et al. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat Genet. 2004;36:476-480.
-
(2004)
Nat Genet
, vol.36
, pp. 476-480
-
-
Stoll, M.1
Corneliussen, B.2
Costello, C.M.3
-
25
-
-
21344435414
-
DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population
-
Noble CL, Nimmo ER, Drummond H, et al. DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population. Gut. 2005;54:1416-1420.
-
(2005)
Gut
, vol.54
, pp. 1416-1420
-
-
Noble, C.L.1
Nimmo, E.R.2
Drummond, H.3
-
26
-
-
21344449654
-
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease
-
Török H-P, Glas J, Tonenchi L, et al. Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Inflamm Bowel Dis. 2005;54:1421-1427.
-
(2005)
Inflamm Bowel Dis
, vol.54
, pp. 1421-1427
-
-
Török, H.-P.1
Glas, J.2
Tonenchi, L.3
-
27
-
-
33645453615
-
DLG5 variants in inflammatory bowel disease
-
Buning C, Geerdts L, Fiedler T, et al. DLG5 variants in inflammatory bowel disease. Am J Gastroenterol. 2006;101:786-792.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 786-792
-
-
Buning, C.1
Geerdts, L.2
Fiedler, T.3
-
28
-
-
33645105960
-
Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort
-
Tremelling M, Waller S, Bredin F, Greenfield S, Parkers M. Genetic variants in TNF-alpha but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort. Inflamm Bowel Dis. 2006;12:178-184.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 178-184
-
-
Tremelling, M.1
Waller, S.2
Bredin, F.3
Greenfield, S.4
Parkers, M.5
-
29
-
-
12744274602
-
Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease
-
Yamazaki K, Takazoe M, Tanaka T, et al. Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease. J Hum Genet. 2004;49:664-668.
-
(2004)
J Hum Genet
, vol.49
, pp. 664-668
-
-
Yamazaki, K.1
Takazoe, M.2
Tanaka, T.3
-
30
-
-
0024810567
-
Classification of inflammatory bowel disease
-
Lennard-Jones JE. Classification of inflammatory bowel disease. Stand J Gastroenterol Suppl. 1989;170:2-6.
-
(1989)
Stand J Gastroenterol Suppl
, vol.170
, pp. 2-6
-
-
Lennard-Jones, J.E.1
-
31
-
-
33748940263
-
CARD15 in inflammatory bowel disease and Crohn's disease phenotypes: An association study and pooled analysis
-
Oostenbrug LE, Nolte IM, Oosterom E, et al. CARD15 in inflammatory bowel disease and Crohn's disease phenotypes: an association study and pooled analysis. Dig Liver Dis. 2006;38:834-845.
-
(2006)
Dig Liver Dis
, vol.38
, pp. 834-845
-
-
Oostenbrug, L.E.1
Nolte, I.M.2
Oosterom, E.3
-
32
-
-
23844495249
-
Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients
-
Braat H, Stokkers P, Hommes T, et al. Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients. J Mol Med. 2005;83:601-609.
-
(2005)
J Mol Med
, vol.83
, pp. 601-609
-
-
Braat, H.1
Stokkers, P.2
Hommes, T.3
-
33
-
-
23944479252
-
Analysis of CARD15 gene variants in Italian pediatric patients with inflammatory bowel diseases
-
Ferraris A, Knafelz D, Torres B, et al. Analysis of CARD15 gene variants in Italian pediatric patients with inflammatory bowel diseases. J Pediatr. 2005;147:272-273.
-
(2005)
J Pediatr
, vol.147
, pp. 272-273
-
-
Ferraris, A.1
Knafelz, D.2
Torres, B.3
-
34
-
-
3342986671
-
NOD2/CARD15 mutation analysis and genotype-phenotype correlation in Jewish pediatric patients compared with adults with Crohn's disease
-
Weiss B, Shamir R, Bujanover Y, et al. NOD2/CARD15 mutation analysis and genotype-phenotype correlation in Jewish pediatric patients compared with adults with Crohn's disease. J Pediatr. 2004;145:208-212.
-
(2004)
J Pediatr
, vol.145
, pp. 208-212
-
-
Weiss, B.1
Shamir, R.2
Bujanover, Y.3
-
35
-
-
0345358673
-
NOD2/CARD15 variants are associated with lower weight at diagnosis in children with Crohn's disease
-
Tomer G, Ceballos C, Concepcion E, Benkov KJ. NOD2/CARD15 variants are associated with lower weight at diagnosis in children with Crohn's disease. Am J Gastroenterol. 2003;98:2479-2484.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 2479-2484
-
-
Tomer, G.1
Ceballos, C.2
Concepcion, E.3
Benkov, K.J.4
-
36
-
-
24344437711
-
Is age of onset of Crohn's disease governed by mutations in NOD2/caspase recruitment domains 15 and Toll-like receptor 4? Evaluation of a pediatric cohort
-
Leshinsky-Silver E, Karban A, et al. Is age of onset of Crohn's disease governed by mutations in NOD2/caspase recruitment domains 15 and Toll-like receptor 4? Evaluation of a pediatric cohort. Pediatr Res. 2005;58:499-504.
-
(2005)
Pediatr Res
, vol.58
, pp. 499-504
-
-
Leshinsky-Silver, E.1
Karban, A.2
-
37
-
-
16644381717
-
Pediatric Crohn's disease and growth retardation: The role of genotype, phenotype, and disease severity
-
Wine E, Reif SS, Leshinsky-Silver E, et al. Pediatric Crohn's disease and growth retardation: the role of genotype, phenotype, and disease severity. Pediatrics. 2004;114:1281-1286.
-
(2004)
Pediatrics
, vol.114
, pp. 1281-1286
-
-
Wine, E.1
Reif, S.S.2
Leshinsky-Silver, E.3
-
38
-
-
27644591952
-
Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease
-
Russell RK, Drummond HE, Nimmo EE, et al. Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease. Inflamm Bowel Dis. 2005;11:955-964.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 955-964
-
-
Russell, R.K.1
Drummond, H.E.2
Nimmo, E.E.3
-
39
-
-
11144279151
-
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
-
Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol. 2004;99:2393-2404.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 2393-2404
-
-
Economou, M.1
Trikalinos, T.A.2
Loizou, K.T.3
Tsianos, E.V.4
Ioannidis, J.P.5
-
40
-
-
14544281031
-
The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway
-
Ouburg S, Mallant-Hent R, Crusius JBA, et al. The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn's disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway. Gut. 2005;54:439-440.
-
(2005)
Gut
, vol.54
, pp. 439-440
-
-
Ouburg, S.1
Mallant-Hent, R.2
Crusius, J.B.A.3
-
41
-
-
13544276471
-
Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population
-
Gazouli M, Mantzaris G, Kotsinas A, et al. Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. World J Gastroenterol. 2005;11:681-685.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 681-685
-
-
Gazouli, M.1
Mantzaris, G.2
Kotsinas, A.3
-
42
-
-
2942689466
-
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: Association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis
-
Török HP, Glas J, Tonenchi L, et al. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin Immunol. 2004;112:85-91.
-
(2004)
Clin Immunol
, vol.112
, pp. 85-91
-
-
Török, H.P.1
Glas, J.2
Tonenchi, L.3
-
43
-
-
4344671141
-
NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: Evidence for genetic heterogeneity within Europe?
-
Arnott ID, Nimmo ER, Drummond HE, et al. NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? Genes Immun. 2004;5:417-425.
-
(2004)
Genes Immun
, vol.5
, pp. 417-425
-
-
Arnott, I.D.1
Nimmo, E.R.2
Drummond, H.E.3
-
44
-
-
20144387613
-
Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations
-
Lakatos PL, Lakatos L, Szalay F, et al. Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations. World J Gastroenterol. 2005;11:1489-1495.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 1489-1495
-
-
Lakatos, P.L.1
Lakatos, L.2
Szalay, F.3
-
45
-
-
33646061100
-
Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth parameters in early-onset inflammatory bowel disease
-
Russell RK, Drummond HE, Nimmo ER, et al. Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth parameters in early-onset inflammatory bowel disease. Gut. 2006;55:1114-1123.
-
(2006)
Gut
, vol.55
, pp. 1114-1123
-
-
Russell, R.K.1
Drummond, H.E.2
Nimmo, E.R.3
-
46
-
-
33645012263
-
Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men
-
Friedrichs F, Brescianini S, Annese V, et al. Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men. Hum Genet. 2006;119:305-311.
-
(2006)
Hum Genet
, vol.119
, pp. 305-311
-
-
Friedrichs, F.1
Brescianini, S.2
Annese, V.3
-
47
-
-
33846509730
-
DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease
-
Biank V, Friedrichs F, Babusukumar U, Wang T, Stoll M, Broeckel U, Kugathasan S. DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease. Am J Gastroenterol. 2007;102:391-398.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 391-398
-
-
Biank, V.1
Friedrichs, F.2
Babusukumar, U.3
Wang, T.4
Stoll, M.5
Broeckel, U.6
Kugathasan, S.7
|