Restoration of the balanced α/β-globin gene expression in β654-thalassemia mice using combined RNAi and antisense RNA approach

Human Molecular Genetics

Volumn 16, Issue 21, 2007, Pages 2616-2625

  Xie, Shu Yang ^a   Ren, Zhao Rui ^a   Zhang, Jing Zhi ^a   Guo, Xin Bin ^a   Wang, Qing Xue ^a   Wang, Shu ^a   Lin, Dan ^a   Gong, Xiu Li ^a   Li, Wei ^a   Huang, Shu Zhen ^a   Zeng, Fanyi ^a   Zeng, Yi Tao ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; BETA GLOBIN; COMPLEMENTARY RNA; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTISENSE THERAPY; ARTICLE; BETA THALASSEMIA; CONTROLLED STUDY; DYSERYTHROPOIESIS; EXTRAMEDULLARY HEMATOPOIESIS; FEASIBILITY STUDY; GENE EXPRESSION; HEMATOLOGICAL PARAMETERS; MOUSE; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROGENY; PROTEIN BLOOD LEVEL; PROTEIN TARGETING; RNA INTERFERENCE; RNA SPLICING; SURVIVAL RATE; SURVIVAL TIME; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

ANEMIA; ANIMALS; BETA-THALASSEMIA; BONE MARROW; ERYTHROPOIESIS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GLOBINS; HEMOGLOBINS; HUMANS; LENTIVIRUS; MICE; MICE, TRANSGENIC; PHENOTYPE; RNA SPLICING; RNA, ANTISENSE; RNA, SMALL INTERFERING;

MUS; MUS MUSCULUS;

EID: 35448973406     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm218     Document Type: Article

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