Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3′-Azido-3′-deoxythymidine and 2′,3′-dideoxyinosine

Environmental and Molecular Mutagenesis

Volumn 39, Issue 4, 2002, Pages 282-295

  Meng, Quanxin ^a   Su, Ting ^b   O'Neill, J Patrick ^c   Walker, Vernon E ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b WADSWORTH CENTER   (United States)

^c UNIVERSITY OF VERMONT   (United States)

Author keywords

AZT; Ddl; HPRT; Mutational spectrum; TK; TK6 cells

Indexed keywords

ANTIRETROVIRUS AGENT; COMPLEMENTARY DNA; DIDANOSINE; GENOMIC DNA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; RNA; RNA DIRECTED DNA POLYMERASE INHIBITOR; THYMIDINE KINASE; ZIDOVUDINE;

CANCER RISK; CHI SQUARE TEST; CONFERENCE PAPER; CONTROLLED STUDY; DNA SEQUENCE; DRUG EXPOSURE; DRUG POTENTIATION; GENE DELETION; GENE INSERTION; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; POINT MUTATION; RANK SUM TEST; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SOUTHERN BLOTTING;

ANTI-HIV AGENTS; B-LYMPHOCYTES; BLOTTING, SOUTHERN; CELL LINE; DIDANOSINE; DNA; DNA MUTATIONAL ANALYSIS; DRUG SYNERGISM; GENE DELETION; GENES, REPORTER; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTAGENICITY TESTS; MUTATION; POINT MUTATION; PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ZIDOVUDINE;

INSERTION SEQUENCES;

EID: 0036305980     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.10073     Document Type: Conference Paper

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