Integrin α6Bβ1 is involved in kidney tubulogenesis in vitro

Journal of Cell Science

Volumn 109, Issue 12, 1996, Pages 2801-2810

  Falk, Mats ^a   Salmivirta, Katriina ^a   Durbeej, Madeleine ^a   Larsson, Erik ^a   Ekblom, Marja ^a   Vestweber, Dietmar ^b   Ekblom, Peter ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

Apoptosis; Epithelium; Integrin; Kidney; Laminin

Indexed keywords

INTEGRIN; LAMININ; LAMININ RECEPTOR;

ANIMAL CELL; ARTICLE; EMBRYO; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; KIDNEY DEVELOPMENT; KIDNEY TUBULE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIBODIES; ANTIGENS, CD29; BLOTTING, NORTHERN; CADHERINS; IN SITU HYBRIDIZATION; INTEGRIN ALPHA6BETA1; INTEGRINS; KIDNEY TUBULES; MICE; POLYMERASE CHAIN REACTION; RECEPTORS, LAMININ;

ANIMALIA;

EID: 0030451419     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Aumailley, M., Timpl, R. and Sonnenberg, A. (1990). Antibody to integrin α6 subunit specifically inhibits cell-binding to laminin fragment 8. Exp. Cell Res. 188, 55-60.
2. Burgeson, R. E., Chiquet, M., Ekblom, P., Engel, J., Kleinman, H., Martin, G. R., Ortonne, J., Paulsson, M., Timpl, R., Tryggvason, K., Yamada, Y. and Yurchenco, P. D. (1994). A new nomenclature for the laminins. Matrix Biol. 14, 209-211.
3. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J. and Rutter, W. J. (1979). Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18, 5294-5299.
4. Durbeej, M., Söderström, S., Ebendal, T., Birchmeier, C. and Ekblom, P. (1993). Differential expression of neurotrophin receptors during renal development. Development 119, 977-989.
5. Durbeej, M., Larsson, E., Ibraghimov-Beskrovnaya, O., Roberds, S. L., Campbell, K. P. and Ekblom, P. (1995). Non-muscle α-dystroglycan is involved in epithelial development. J. Cell Biol. 130, 79-91.
6. Ekblom, P., Vestweber, D. and Kemler, R. (1986). Cell-matrix interactions and cell adhesion during development. Annu. Rev. Cell Biol. 2, 27-47.
7. Ekblom, M., Klein, G., Mugrauer, G., Fecker, L., Deutzmann, R., Timpl, R. and Ekblom, P. (1990). Transient and locally restricted expression of laminin A chain mRNA by developing epithelial cells during kidney organogenesis. Cell 60, 337-346.
8. Ekblom, P. (1992). Renal development. In The Kidney: Physiology and Pathophysiology (ed. D. W. Seldin and G. Giebisch), pp. 475-501. Raven Press, Ltd, New York.
9. Ekblom, P. (1993). Basement membranes in development. In Molecular and Cellular Aspects of Basement Membranes (ed. R. Timpl and D. H. Rohrbach), pp. 359-383.
10. Frisch, S. M. and Francis, H. (1994). Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 12, 619-626.
11. Grobstein, C. (1955). Inductive interaction in the development of the mouse metanephros. J. Exp. Zool. 130, 319-340.
12. Grobstein, C. (1956). Trans-filter induction of kidney tubules in mouse metanephric mesenchyme. Exp. Cell Res. 10, 424-440.
13. Gullberg, D., Terracio, L., Borg, T. K. and Rubin, K. (1989). Identification of integrin-like matrix receptors with affinity for interstitial collagens. J. Biol. Chem. 264, 12686-12694.
14. Hatta, K., Takagi, S., Fujisawa, H. and Takeichi, M. (1987). Spatial and temporal expression patterns of N-cadherin adhesion molecules correlated with morphogenetic processes in chicken embryos. Dev. Biol. 120, 215-227.
15. Hierck, B. P., Thorsteinsdóttir, S., Niessen, C. M., Freund, E., Iperen, L. V., Feyen, A., Hogervorst, F., Poelmann, R. E., Mummery, C. L. and Sonnenberg, A. (1993). Variants of the α6β1 laminin receptor in early murine development: distribution, molecular cloning and chromosomal localization of the mouse integrin α6 subunit. Cell Adhes. Commun, 1, 33-53.
16. Hogervorst, F., Kuikman, I., Geurts van Kessel, A. and Sonnenberg, A. (1991). Molecular cloning of the human α6 integrin subunit. Alternative splicing of α6 mRNA and chromosomal localization of the α6 and β4 genes. Eur. J. Biochem. 199, 425-433.
17. Hogervorst, F., Admiraal, L. G., Niessen, C., Kuikman, I., Janssen, H., Daams, H. and Sonnenberg, A. (1993). Biochemical characterization and tissue distribution of the A and B variant of the integrin α6 subunit. J. Cell Biol. 121, 179-191.
18. Holers, V. M., Ruff, T. G., Parks, D. L., McDonald, J. A., Ballard, L. L. and Brown, E. L. (1989). Molecular cloning of a murine fibronectin receptor and its expression during inflammation. Expression of VLA-5 is increased in activated peritoneal macrophages in a manner discordant from major histocompatibility complex class II. J. Exp. Med. 169, 1589-1605.
19. Kadoya, Y., Kadoya, K., Durbeej, M., Holmvall, K., Sorokin, L. and Ekblom, P. (1995). Antibodies against domain E3 of laminin-1 and integrin α6 subunit perturb branching epithelial morphogenesis of submandibular gland, but by different modes. J. Cell Biol. 129, 521-534.
20. Kemler, R. (1993). From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9, 317-321.
21. Kennel, S. J., Foote, L. J., Falcioni, R., Sonnenberg, A., Stringer, C. D., Crouse, C. and Hemler, M. E. (1989). Analysis of the tumor-associated antigen TSP-180. Identity with α6β4 in the integrin superfamily. J. Biol. Chem. 264, 15515-15521.
22. Kennel, S. J., Godfrey, V., Ch'ang, L. Y., Lankford, T. K., Foote, L. J. and Makkinje, A. (1992). The β4 subunit of the integrin family is displayed on a restricted subset of endothelia in mice. J. Cell Sci. 101, 145-150.
23. Kennel, S. J., Foote, L. J., Cimino, L., Rizzo, M. G., Chang, L. Y. and Sacchi, A. (1993). Sequence of a cDNA encoding the β4 subunit of murine integrin. Gene 130, 209-216.
24. Klein, G., Langegger, M., Timpl, R. and Ekblom, P. (1988). Role of laminin A chain in the development of epithelial cell polarity. Cell 55, 331-341.
25. Korhonen, M., Ylänne, J., Laitinen, L. and Virtanen, I. (1990a). The distribution of β1 and β3 integrins in human fetal and adult kidney. Lab. Invest 62, 616-625.
26. Korhonen, M., Ylänne, J., Laitinen, L. and Virtanen, I. (1990b). The α1-α6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron. J. Cell Boil. 111, 1245-1254.
27. Larue, L., Ohsugi, M., Hirchenhain, J. and Kemler, R. (1994). E-cadherin null mutant embryos fail to form a trophectoderm. Proc. Nat. Acad. Sci. USA 91, 8263-8267.
28. Lee, M. M., Lotz, C. A., Steele, G. D. Jr and Mercurio, A. M. (1992). The integrin α6β4 is a laminin receptor. J. Cell Biol. 117, 671-678.
29. Lenter, M., Uhlig, H., Hamann, A., Jenö, P., Imhof, B. and Vestweber, D. (1993). A monoclonal antibody against an activation epitope on mouse integrin chain β1 blocks adhesion of lymphocytes to the endothelial integrin α6β1. Proc. Nat. Acad. Sci. USA 90, 9051-9055.
30. Matlin, K. S. and Caplan, M. J. (1992). Epithelial cell structure and polarity. The Kidney: Physiology and Pathophysiology (ed. D. W. Seldin and G. Geibisch ), pp. 475-501. Raven Press, New York.
31. Meredith, J. E., Fazeli, B. and Schwarz, M. A. (1993). The extracellular matrix as a cell survival factor. Mol. Biol. Cell. 4, 953-961.
32. Natali, P. G., Nicotra, M. R., Bigotti, A. and Demartino, C. (1992). Localization of the α6 and β4 integrin subunits in normal human non-lymphoid tissues. J. Cell Sci. 103, 1243-1247.
33. Niessen, C. M., Hogervorst, F., Jaspers, L. H., de Melker, A. A., Delwel, G., Hulsman, E., Kuikman, I. and Sonnenberg, A, (1994). The α6β4 integrin is a receptor for both laminin and kalinin. Exp. Cell Res. 211, 360-367.
34. Rodriguez-Boulan, E. and Nelson, W. J. (1989). Morphogenesis of the polarized epithelial phenotype. Science 245, 718-725.
35. Salmivirta, K., Gullberg, D., Hirsch, E., Altruda, F. and Ekblom, P. (1996). Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. Dev. Dynamics 206 (in press).
36. Saxén, L., Koskimies, O., Lahti, A., Miettinen, H., Rapola, J. and Wartiovaara, J. (1968). Differentiation of kidney mesenchyme in an experimental model system. Advan. Morphogen. 7, 251-293.
37. Schoenenberger, C.-A., Zuk, A., Zinnkl, G. M., Kendall, D. and Matlin, K. S. (1994). Inlegrin expression and localization in normal MDCK cells and transformed MDCK cells lacking apical polarity. J. Cell Sci. 107, 527-541.
38. Shaw, L. M., Turner, C. E. and Mearcurio, A. M. (1995). The α6Aβ1 and α6Bβ1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins. J. Biol. Chem. 270, 23648-23652.
39. Sonnenberg, A., Linders, C. J. T., Daams, J. H. and Kennel, S. J. (1990a). The α6β1 (VLA-6) and α6β4 protein complexes: tissue distribution and biochemical properties. J. Cell Sci. 96, 207-217.
40. Sonnenberg, A., Linders, C. J. T., Modderman, P. W., Damsky, C. H., Aumailley, M. and Timpl, R. (1990b). Integrin recognizing of different cell-binding fragments of laminin (P1, E3, E8) and evidence that α6β1 but not α6β4 functions as a major receptor for fragment E8. J. Cell Biol. 110, 2145-2155.
41. Sonnenberg, A., Calafat, J., Janssen, H., Daams, H., van der Raaij-Helmer, L. M. H., Falcioni, R., Kennel, S. J., Aplin, J. D., Baker, J., Loizidou, M. and Garrod, D. (1991). Integrin α6/β4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion. J. Cell Biol. 113, 907-917.
42. Sonnenberg, A., de Melker, A. A., Martinez de Velasco, A. M., Janssen, H., Calafat, J. and Niessen, C. M. (1993). Formation of hemidesmosomes in cells of a transformed murine cell line and mechanisms involved in adherance of these cells to laminin and kalinin. J. Cell Sci. 106, 1083-1102.
43. Sorokin, L., Sonnenberg, A., Aumailley, M., Timpl, R. and Ekblom, P. (1990). Recognition of the laminin E8 cell-binding site by an integrin possessing the α6 subunit is essential for epithelial polarization in developing kidney tubules. J. Cell Biol. 111, 1265-1274.
44. Spinardi, L., Einheber, S., Cullen, T., Milner, T. A. and Giancotti, F. (1995). A recombinant tail-less integrin β4 subunit disrupts hemidesomosomes, but does not suppress α6β4-mediated cell adhesion to laminins. J. Cell Biol. 129, 473-487.
45. Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
46. Tamura, R. N., Rozzo, C., Stan, L., Chambers, J., Reichardt, L. F., Cooper, H. M. and Quaranta, V. (1990). Epithelial integrin α6β4: Complete primary structure of α6 and variant forms of β4. J. Cell Biol. 111, 1593-1604.
47. Tamura, R. N., Cooper, H. M., Collo, G. and Quaranta, V. (1991). Cell type-specific integrin variants with alternative α chain cytoplasmic domains. Proc. Nat. Acad. Sci. USA 88, 10183-10187.
48. Tarone, G., Russo, M. A., Hirsch, E., Odorisio, T., Altruda, F., Silengo, L. and Siracusa, G. (1993). Expression of β1 integrin complexes on the surface of unfertilized mouse oocyte. Development 117, 1369-1375.
49. Timpl, R. and Brown, J. C. (1994). The laminins. Matrix Biol. 14, 275-281.
50. Tözeren, A., Kleinman, H. K., Wu, S., Mercurio, A. M. and Byers, S. W. (1994). Integrin α6β4 mediates dynamic interactions with laminin. J. Cell Sci. 107, 3153-3163.
51. Vestweber, D. and Kemler, R. (1985). Identification of a putative cell adhesion domain of uvomorulin. EMBOJ. 4, 3393-3398.
52. Vestweber, D., Kemler, R. and Ekblom P. (1985). Cell-adhesion molecule uvomorulin during kidney development. Dev Biol. 112, 213-221.
53. Xiang, Y., Tanaka, M., Suzuki, M., Igarashi, H., Kiyokawa, E., Naito, Y., Ohtawara, Y., Shen, Q., Sugimura, H. and Kino, I. (1994). Isolation of complementary DNA encoding K-cadherin, a novel rat cadherin preferentially expressed in fetal kidney and kidney carcinoma. Cancer Res. 54, 3034-3041.