Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 293, Issue 4, 2007, Pages

  Garneau, Hugo ^a   Alvarez, Laetitia ^a   Paquin, Marie Christine ^a   Lussier, Carine ^a   Rancourt, Claudine ^a   Tremblay, Éric ^a   Beaulieu, Jean Francois ^a   Rivard, Nathalie ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Colon cancer; E2F; Intestinal epithelial crypt apoptosis; p53

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; FAS ANTIGEN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN JNK1; PROTEIN P14ARF; PROTEIN P53; PROTEIN PUMA; PROTEIN RIP; SERINE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR E2F4; UNCLASSIFIED DRUG;

ADENOVIRUS; APOPTOSIS; ARTICLE; BAX GENE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; CRYPT CELL; CYTOPLASM; DOWN REGULATION; ENZYME ACTIVATION; GENE; GENE MUTATION; HUMAN; HUMAN CELL; MITOGENESIS; NUCLEAR LOCALIZATION SIGNAL; P53 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; RNA INTERFERENCE; WILD TYPE;

APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; COLONIC NEOPLASMS; E2F4 TRANSCRIPTION FACTOR; HUMANS; INTESTINAL MUCOSA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 35349011041     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00050.2007     Document Type: Article

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