Effect of erythropoietin on brain tissue after experimental head trauma in rats

Surgical Neurology

Volumn 68, Issue 5, 2007, Pages 547-555

  Akdemir Ozisik, Pinar ^a   Oruckaptan, Hakan ^a   Ozdemir Geyik, Pinar ^a   Misirlioglu, Muge ^b   Sargon, Mustafa F ^a   Kilinc, Kamer ^a   Ozgen, Tuncalp ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b Metis Biotechnology Ltd   (Turkey)

Author keywords

Apoptosis; bcl 2; Brain injury; Electron microscopy; Erythropoietin; Lipid peroxidation; Methylprednisolone; Survivin

Indexed keywords

METHYLPREDNISOLONE SODIUM SUCCINATE; PROTEIN BCL 2; RECOMBINANT ERYTHROPOIETIN; SURVIVIN;

ANIMAL MODEL; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; GENE EXPRESSION; GENETIC ANALYSIS; HEAD INJURY; LIPID PEROXIDATION; NEUROPROTECTION; NONHUMAN; RAT; SCORING SYSTEM; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN; BRAIN INJURIES; ERYTHROPOIETIN, RECOMBINANT; FREE RADICALS; LIPID PEROXIDATION; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 35348967341     PISSN: 00903019     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.surneu.2007.01.030     Document Type: Article

References (45)

1. Adida C., Crotty P.L., Mcgrath J., Berrebi D., Diebold J., and Altieri D.C. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol 152 (1998) 43-44
2. Anderson D.K., Dugan L.L., Means E.D., and Horrocks L.A. Methylprednisolone and membrane properties of primary cultures of mouse spinal cord. Brain Res 637 (1994) 119-125
3. Aoki Y., Tamura M., Itoh Y., Seto T., Nonaka K., Mukai H., and Ukai Y. Effective plasma concentration of a novel Na+/Ca+ channel blocker NS-7 for its cerebroprotective actions in rats with a transient middle cerebral artery occlusion. J Pharmacol Exp Ther 296 (2001) 306-311
4. Bany-Mohammed F.M., Slivka S., and Hallman M. Recombinant human erythropoietin: possible role as an antioxidant in premature rabbits. Pediatr Res 40 (1996) 381-387
5. Bourke R.S., Kimelberg H.K., and Daze M.A. Studies on the formation of astroglial swelling and its inhibition by clinically useful agents. In: Popp A.J., Bourke R.S., Nelson L.R., and Kimelberg H.K. (Eds). Neural trauma (1979), Raven Press, NY 95-113
6. Braughler J.M., and Hall E.D. Correlation of methylprednisolone levels in cat spinal cord with its effect on (Na+-K+) ATPase, lipid peroxidation and alpha motor neuron function. Neurosurgery 56 (1982) 838-844
7. Braughler J.M., and Lainer M.J. The effects of large doses of methylprednisolone on neurologic recovery and survival in the Mongolian gerbil following three hours of unilateral carotid occlusion. Cent Nerv Syst Trauma 3 (1986) 153-162
8. Buemi M., Cavallaro E., Floccari F., Sturiale A., Aloisi C., Trimarchi M., Grasso G., Corica F., and Frinisa N. Erythropoietin and the brain: from neurodevelopment to neuroprotection. Clin Sci (Lond) 103 (2002) 275-282
9. Cheung N.S., Beart P.M., Pascoe C.J., John C.A., and Bernard O. Human bcl-2 protects against AMPA receptor-mediated apoptosis. J Neurochem 74 (2000) 1613-1620
10. CRASH Trial collaborators. Effect of intravenous corticosteroids on death within 14 days in 10 008 adults with clinically significant head injury (MRC CRASH trial): randomized placebo-controlled trial. Lancet 364 (2004) 1321-1328
11. Deveraux Q.L., and Reed J.C. IAP family proteins-suppressors of apoptosis. Genes Dev 13 (1999) 239-252
12. Dogan A., Rao A.M., Hatcher J., Rao V.L.R., Baskaya M.K., and Dempsey R.J. Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. J Neurochem 72 (1999) 765-770
13. Eid T., and Brines M. Recombinant human erythropoietin for neuroprotection: what is the evidence?. Clin Breast Cancer 3 Suppl 3 (2002) 109-115
14. Fujimoto S., Mizoi K., Yoshimoto T., and Suzuki J. The protective effect of vitamin E on cerebral ischemia. Surg Neurol 22 (1984) 449-454
15. Hall E.D., and Braughler J.M. Free radicals in CNS injury. In: Waxman S.G. (Ed). Molecular and cellular approaches to the treatment of neurological diseases (1993), Raven Press, NY 81-105
16. Hall E.D. High-dose glucocorticoid treatment improves neurological recovery in head-injured mice. J Neurosurg 62 (1985) 882-887
17. Ildan F., Polat S., Oner A., Isbir T., Cetinalp T., Kaya M., and Karadayi A. The effect of the treatment of high dose methylprednisolone on Na+-K+/Mg+2 ATPase activity and lipid peroxidation and ultrastructural findings following cerebral contusion in rat. Surg Neurol 44 (1995) 573-580
18. Jelkmann W. Erythropoietin: structure, control of production, and function. Physiol Rev 72 (1992) 672-676
19. Johnson E.A., Svetlov S.I., Pike B.R., Tolentino P.J., Shaw G., Wang K.W., Hayes R.L., and Pineda J.A. Cell-specific upregulation of Survivin after experimental traumatic brain injury in rats. J Neurotrauma 21 (2004) 1183-1195
20. Kalinina O., Lebedeva I., Brown J., and Silver J. Nanoliter scale PCR with TaqMan detection. Nucleic Acids Res 25 (1997) 1999-2004
21. Kirkali Z., Esen A.A., Hayran M., Gencbay A., Gidener S., Guven H., and Gure A. The effect of extracorporeal electromagnetic shock waves on the morphology and contractility of the rabbit ureter. J Urol 154 (1995) 1939-1943
22. Kiwak K.J., Moskowitz M.A., and Levine L. Leukotriene production in gerbil brain after ischemic insult, subarachnoid hemorrhage and concussive head injury. J Neurosurg 62 (1985) 865-869
23. Kleindienst A., Marmarou A., Fazzina G., Amorini A.M., Dunbar J.G., and Glisson R. Protective effect of the V1a receptor antagonist SR49059 on brain edema formation following middle cerebral artery occlusion in the rat. Poster presentation in "13th International Symposium on Brain Edema and Conference on Intracerebral Hemorrhage". Ann Arbor, Michigan; May 31-June 4 (2005)
24. Kobayashi K., Hatano M., Otaki M., Ogasawara T., and Tokuhisa T. Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc Natl Acad Sci U S A 96 (1999) 1457-1462
25. Koc R.K., Kurtsoy A., Pasaoglu H., Karakucuk E.I., Oktem I.S., and Meral M. Lipid peroxidation and edema in experimental brain injury: comparison of treatment with methylprednisolone, tirilazad mesylate and vitamin E. Res Exp Med 199 (1999) 21-28
26. Kontos H.A., and Povlishock J.T. Oxygen radicals in brain injury. Cent Nerv Syst Trauma 3 (1986) 257-263
27. Kumral A., Uysal N., Tugyan K., Sonmez A., Yilmaz O., Gokmen N., Kiray M., Genc S., Duman N., Koroglu T.F., Ozkan H., and Genc K. Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats. Behav Brain Res 153 (2004) 77-86
28. Martinou J.C., Dubois-Dauphin M., Staple J.K., Rodriguez I., Frankowski H., Missotten M., Albertini P., Talabot D., Catsicas S., and Pietra C. Overexpression of bcl-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 13 (1994) 1017-1030
29. Matsuo Y., Mihara S., Ninomiya M., and Fujimoto M. Protective effect of endothelin type A receptor antagonist on brain edema and injury after transient middle cerebral artery occlusion in rats. Stroke 32 (2001) 2143-2148
30. Meyer J.S., Charney J., Rivera V.M., and Mathew M.T. Treatment with glycerol of cerebral edema due to acute cerebral infarction. Lancet 2 (1971) 933-977
31. Mihara S., and Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86 (1978) 271-278
32. Minn A.J., Velez P., Schendel S.L., Liang H., Muchmore S.W., Fesik S.W., Fill M., and Thompson C.B. Bcl-x(L) forms an ion channel in synthetic lipid membrane. Nature 385 (1997) 353-357
33. Muchmore S.W., Chen J., Jakob C., Zakula D., Matayoshi E.D., Wu W., Zhang H., Li F., Ng S.C., and Aaltieri D.C. Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin. Mol Cell 6 (1999) 213-218
34. Ohlsson M., Westerlund U., Langmoen I.A., and Svensson M. Methylprednisolone treatment does not influence axonal regeneration or degeneration following optic nerve injury in the adult rat. J Neuro-Ophtalmol 24 (2004) 11-18
35. Ozisik K., Yildirim E., Kaplan S., Solaroglu I., Sargon M., and Kilinc K. Ultrastructural changes of rat cardiac myocytes in a time-dependent manner after traumatic brain injury. Am J Transplant 4 (2004) 900-904
36. Paydas S., Tanriverdi K., Yavuz S., Disel U., Sahin B., and Burgut R. Survivin and aven: two distinct antiapoptotic signals in acute leukemias. Ann Oncol 14 (2003) 1045-1050
37. Peirson S.N., Butler J.N., and Foster R.G. Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res 31 14 (2003) 73
38. Shingo T., Sorokan S.T., Shimazaki T., and Weiss S. Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J Neurosci 21 (2001) 9733-9743
39. Simonati A., Tosati C., Rosso T., Piazzola E., and Rizzuto N. Cell proliferation and death: morphological evidence during corticogenesis in the developing human brain. Microsc Res Tech 45 (1999) 341-352
40. Tanabe H., Eguchi Y., Kamada S., Martinou J.C., and Tsujimoto Y. Susceptibility of cerebellar granule neurons derived from bcl-2-deficient and transgenic mice to cell death. Eur J Neurosci 9 (1997) 848-856
41. Tron V.A., Krajewski S., Lkein-Parker H., Li G., Ho V.C., and Reed J.C. Immunohistochemical analysis of Bcl-2 protein regulation in cutaneous melanoma. Am J Pathol 146 (1995) 643-650
42. Veis D.J., Sorenson C.M., Shutter J.R., and Korsmeyer S.J. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75 (1993) 229-240
43. Wang L., Zhang Z., Wang Y., Zhang R., and Chopp M. Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological functions in rats. Stroke 35 (2004) 1732-1737
44. Yamada Y., Watanabe Y., Zhang J., Haraoka J., and Ito H. Changes in cortical and cerebellar bcl-2 mRNA levels in the developing hydrocephalic rat (LEW-HYR) as measured by a real time quantified RT-PCR. Neuroscience 114 (2002) 165-171
45. Zamzami N., Susin S.A., and Kromer G. Mitochondrial control of apoptosis. Immunol Today 18 (1997) 44-51