메뉴 건너뛰기




Volumn 4, Issue 2, 2007, Pages 66-75

Pharmacogenetic studies investigating the adverse effects of antipsychotics

Author keywords

Adverse effects; Antipsychotics; Pharmacogenetics; Tardive dyskinesia; Weight gain

Indexed keywords

ACYLTRANSFERASE; ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DNA; MYELOPEROXIDASE; OLANZAPINE; RISPERIDONE; THIOPURINE METHYLTRANSFERASE; ZIPRASIDONE;

EID: 35348959536     PISSN: 17383684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (140)
  • 1
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: A critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • Miyamoto S, Duncan GE, Marx CE, Lieberman JA. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 2005;10:79-104.
    • (2005) Mol Psychiatry , vol.10 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 2
  • 3
    • 33645793568 scopus 로고    scopus 로고
    • Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care
    • Ascher-Svanum H, Faries DE, Zhu B, Ernst FR, Swartz MS, Swanson JW. Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care. J Clin Psychiatry 2006;67:453-460.
    • (2006) J Clin Psychiatry , vol.67 , pp. 453-460
    • Ascher-Svanum, H.1    Faries, D.E.2    Zhu, B.3    Ernst, F.R.4    Swartz, M.S.5    Swanson, J.W.6
  • 4
    • 0036357801 scopus 로고    scopus 로고
    • Antipsychotic medication adherence: Is there a difference between typical and atypical agents?
    • Dolder CR, Lacro JP, Dunn LB, Jeste DV. Antipsychotic medication adherence: is there a difference between typical and atypical agents? Am J Psychiatry 2002;159:103-108.
    • (2002) Am J Psychiatry , vol.159 , pp. 103-108
    • Dolder, C.R.1    Lacro, J.P.2    Dunn, L.B.3    Jeste, D.V.4
  • 5
    • 0032850678 scopus 로고    scopus 로고
    • Use patterns for antipsychotic medications in Medicaid patients with schizophrenia
    • McCombs JS, Nichol MD, Stimmel GL, Shi J, Smith RR. Use patterns for antipsychotic medications in Medicaid patients with schizophrenia. J Clin Psychiatry 1999;60 (suppl 19):5-11.
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 19 , pp. 5-11
    • McCombs, J.S.1    Nichol, M.D.2    Stimmel, G.L.3    Shi, J.4    Smith, R.R.5
  • 6
    • 0033828231 scopus 로고    scopus 로고
    • The evolution of drug metabolism
    • Nebert DW, Dieter MZ. The evolution of drug metabolism. Pharmacology 2000;61:124-135.
    • (2000) Pharmacology , vol.61 , pp. 124-135
    • Nebert, D.W.1    Dieter, M.Z.2
  • 7
    • 0029808456 scopus 로고    scopus 로고
    • Influence of pharmacogenetics on drug disposition and response
    • Eichelbaum M, Evert B. Influence of pharmacogenetics on drug disposition and response. Clin Exp Pharmacol Physiol 1996;23:983-985.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 983-985
    • Eichelbaum, M.1    Evert, B.2
  • 8
    • 0028186982 scopus 로고
    • Genetic polymorphism of cytochrome P450. Functional consequences and possible relationship to disease and alcohol toxicity
    • Ingelman-Sundberg M, Johansson I, Persson I, Oscarson M, Hu Y, Bertilsson L, et al. Genetic polymorphism of cytochrome P450. Functional consequences and possible relationship to disease and alcohol toxicity. EXS 1994;71:197-207.
    • (1994) EXS , vol.71 , pp. 197-207
    • Ingelman-Sundberg, M.1    Johansson, I.2    Persson, I.3    Oscarson, M.4    Hu, Y.5    Bertilsson, L.6
  • 9
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 2002;3:229-243.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 10
    • 0034094251 scopus 로고    scopus 로고
    • Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes
    • Kubota T, Yamaura Y, Ohkawa N, Hara H, Chiba K. Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes. Br J Clin Pharmacol 2000;50:31-34.
    • (2000) Br J Clin Pharmacol , vol.50 , pp. 31-34
    • Kubota, T.1    Yamaura, Y.2    Ohkawa, N.3    Hara, H.4    Chiba, K.5
  • 11
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotypc of drug response
    • Kirchheiner J, Nickchen K, Bauer M, Wong ML, Licinio J, Roots I, et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotypc of drug response. Mol Psychiatry 2004;9:442-473.
    • (2004) Mol Psychiatry , vol.9 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3    Wong, M.L.4    Licinio, J.5    Roots, I.6
  • 13
    • 13844320650 scopus 로고    scopus 로고
    • The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation
    • de Leon J, Susce MT, Pan RM, Fairchild M, Koch WH, Wedlund PJ. The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation. J Clin Psychiatry 2005;66:15-27.
    • (2005) J Clin Psychiatry , vol.66 , pp. 15-27
    • de Leon, J.1    Susce, M.T.2    Pan, R.M.3    Fairchild, M.4    Koch, W.H.5    Wedlund, P.J.6
  • 14
    • 20144373429 scopus 로고    scopus 로고
    • Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6
    • Kakihara S, Yoshimura R, Shinkai K, Matsumoto C, Goto M, Kaji K, et al. Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6. Int Clin Psychopharmacol 2005;20:71-78.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 71-78
    • Kakihara, S.1    Yoshimura, R.2    Shinkai, K.3    Matsumoto, C.4    Goto, M.5    Kaji, K.6
  • 16
    • 0030077735 scopus 로고    scopus 로고
    • Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine
    • Ring BJ, Catlow J, Lindsay TJ, Gillespie T, Roskos LK, Cerimele BJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther 1996;276:658-666.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 658-666
    • Ring, B.J.1    Catlow, J.2    Lindsay, T.J.3    Gillespie, T.4    Roskos, L.K.5    Cerimele, B.J.6
  • 17
    • 0032908778 scopus 로고    scopus 로고
    • Functional significance of a C - >A polymorphism in intron I of the cytochrome P450 CYP1A2 gene tested with caffeine
    • Sachse C, Brockmoller J, Bauer S, Roots I. Functional significance of a C - >A polymorphism in intron I of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 1999;47:445-449.
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 445-449
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 18
    • 9144230034 scopus 로고    scopus 로고
    • Six novel nonsynony mous CYP1A2 gene polymorphisms: Catalytic activities of the naturally occurring variant enzymes
    • Murayama N, Soyama A, Saito Y, Nakajima Y, Komamura K, Ueno K, et al. Six novel nonsynony mous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes. J Pharmacol Exp Ther 2004;308:300-306.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 300-306
    • Murayama, N.1    Soyama, A.2    Saito, Y.3    Nakajima, Y.4    Komamura, K.5    Ueno, K.6
  • 19
    • 18844455524 scopus 로고    scopus 로고
    • The cytochrome P450 CYP1A2 genetic polymorphisms *IF and *ID do not affect clozapine clearance in a group of schizophrenic patients
    • Kootstra-Ros JE, Smallegoor W, van der WJ. The cytochrome P450 CYP1A2 genetic polymorphisms *IF and *ID do not affect clozapine clearance in a group of schizophrenic patients. Ann Clin Biochem 2005;42:216-219.
    • (2005) Ann Clin Biochem , vol.42 , pp. 216-219
    • Kootstra-Ros, J.E.1    Smallegoor, W.2    van der, W.J.3
  • 20
    • 18244426328 scopus 로고    scopus 로고
    • Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C - >A polymorphism in intron 1 of the CYP1A2 gene: Effect of grapefruit juice and low-dose fluvoxamine
    • Ozdemir V, Kalow W, Okey AB, Lam MS, Albers LJ, Reist C, et al. Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C - >A polymorphism in intron 1 of the CYP1A2 gene: effect of grapefruit juice and low-dose fluvoxamine. J Clin Psychopharmacol 2001;21:603-607.
    • (2001) J Clin Psychopharmacol , vol.21 , pp. 603-607
    • Ozdemir, V.1    Kalow, W.2    Okey, A.B.3    Lam, M.S.4    Albers, L.J.5    Reist, C.6
  • 22
    • 0035197548 scopus 로고    scopus 로고
    • Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos
    • Dai D, Tang J, Rose R, Hodgson E, Bienstock RJ, Mohrenweiser HW, et al. Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. J Pharmacol Exp Ther 2001;299:825-831.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 825-831
    • Dai, D.1    Tang, J.2    Rose, R.3    Hodgson, E.4    Bienstock, R.J.5    Mohrenweiser, H.W.6
  • 23
    • 0032980471 scopus 로고    scopus 로고
    • Metabolism, pharmacogenetics, and metabolic drug-drug interactions of antipsychotic drugs
    • Fang J, Gorrod JW. Metabolism, pharmacogenetics, and metabolic drug-drug interactions of antipsychotic drugs. Cell Mol Neurobiol 1999;19:491-510.
    • (1999) Cell Mol Neurobiol , vol.19 , pp. 491-510
    • Fang, J.1    Gorrod, J.W.2
  • 24
    • 30344457586 scopus 로고    scopus 로고
    • A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
    • Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, et al. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther 2006;79:103-113.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 103-113
    • Sim, S.C.1    Risinger, C.2    Dahl, M.L.3    Aklillu, E.4    Christensen, M.5    Bertilsson, L.6
  • 25
    • 11244284872 scopus 로고    scopus 로고
    • Upstream and coding region CYP2C9 polymorphisms: Correlation with warfarin dose and metabolism
    • King BP, Khan TI, Aithal GP, Kamali F, Daly AK. Upstream and coding region CYP2C9 polymorphisms: correlation with warfarin dose and metabolism. Pharmacogenetics 2004;14:813-822.
    • (2004) Pharmacogenetics , vol.14 , pp. 813-822
    • King, B.P.1    Khan, T.I.2    Aithal, G.P.3    Kamali, F.4    Daly, A.K.5
  • 26
    • 33745944880 scopus 로고    scopus 로고
    • AmpliChip CYP450 test: Personalized medicine has arrived in psychiatry
    • de Leon J. AmpliChip CYP450 test: personalized medicine has arrived in psychiatry. Expert Rev Mol Diagn 2006;6:277-826.
    • (2006) Expert Rev Mol Diagn , vol.6 , pp. 277-826
    • de Leon, J.1
  • 27
    • 32644479571 scopus 로고    scopus 로고
    • Genetic basis of toxic reactions to drugs and chemicals
    • Cascorbi I. Genetic basis of toxic reactions to drugs and chemicals. Toxicol Lett 2006;162:16-28.
    • (2006) Toxicol Lett , vol.162 , pp. 16-28
    • Cascorbi, I.1
  • 28
    • 1942421701 scopus 로고    scopus 로고
    • Pharmacogenetics of cytochrome P450 and its applications in drug therapy: The past, present and future
    • Ingelman-Sundberg M. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future. Trends Pharmacol Sci 2004;25:193-200.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 193-200
    • Ingelman-Sundberg, M.1
  • 29
    • 0032868798 scopus 로고    scopus 로고
    • The role of serotonin in antipsychotic drug action
    • Meltzer HY. The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 1999;21 (suppl 2):106-115.
    • (1999) Neuropsychopharmacology , vol.21 , Issue.SUPPL. 2 , pp. 106-115
    • Meltzer, H.Y.1
  • 30
    • 0025053583 scopus 로고
    • Neuroleptic-induced vacuous chewing movements as an animal model of tardive dyskinesia: A study in three rat strains
    • Tamminga CA, Dale JM, Goodman L, Kaneda H, Kaneda N. Neuroleptic-induced vacuous chewing movements as an animal model of tardive dyskinesia: a study in three rat strains. Psychopharmacology (Berl) 1990;102:474-478.
    • (1990) Psychopharmacology (Berl) , vol.102 , pp. 474-478
    • Tamminga, C.A.1    Dale, J.M.2    Goodman, L.3    Kaneda, H.4    Kaneda, N.5
  • 31
    • 0019782863 scopus 로고
    • Familial tardive dyskinesia
    • Yassa R, Ananth J. Familial tardive dyskinesia. Am J Psychiatry 1981;138:1618-1619.
    • (1981) Am J Psychiatry , vol.138 , pp. 1618-1619
    • Yassa, R.1    Ananth, J.2
  • 32
    • 0017396773 scopus 로고
    • The pathophysiologic basis of tardive dyskinesia
    • Tarsy D, Baldessarini RJ. The pathophysiologic basis of tardive dyskinesia. Biol Psychiatry 1977;12:431-450.
    • (1977) Biol Psychiatry , vol.12 , pp. 431-450
    • Tarsy, D.1    Baldessarini, R.J.2
  • 33
    • 0028114486 scopus 로고
    • An overview of the mechanism of action of clozapine
    • Meltzer HY. An overview of the mechanism of action of clozapine. J Clin Psychiatry 1994:55 (suppl B):47-52.
    • (1994) J Clin Psychiatry , vol.55 , Issue.SUPPL. B , pp. 47-52
    • Meltzer, H.Y.1
  • 35
    • 0034256946 scopus 로고    scopus 로고
    • Neurotoxicity associated with neuroleptic-induced oral dyskinesias in rats. Implications for tardive dyskinesia?
    • Andreassen OA, Jorgensen HA. Neurotoxicity associated with neuroleptic-induced oral dyskinesias in rats. Implications for tardive dyskinesia? Prog Neurobiol 2000;61:525-541.
    • (2000) Prog Neurobiol , vol.61 , pp. 525-541
    • Andreassen, O.A.1    Jorgensen, H.A.2
  • 36
    • 0030975438 scopus 로고    scopus 로고
    • Association of TaqI A polymorphism of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia
    • Chen CH, Wei FU, Koong FJ, Hsiao KJ. Association of TaqI A polymorphism of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia. Biol Psychiatry 1997;41:827-829.
    • (1997) Biol Psychiatry , vol.41 , pp. 827-829
    • Chen, C.H.1    Wei, F.U.2    Koong, F.J.3    Hsiao, K.J.4
  • 37
    • 0041825283 scopus 로고    scopus 로고
    • Chong SA, Tan EC, Tan CH, Mythily, Chan YH. Polymorphisms of dopamine receptors and tardive dyskinesia among Chinese patients with schizophrenia. Am J Med Genet B Neuropsychiatr Genet 2003;11631-54.
    • Chong SA, Tan EC, Tan CH, Mythily, Chan YH. Polymorphisms of dopamine receptors and tardive dyskinesia among Chinese patients with schizophrenia. Am J Med Genet B Neuropsychiatr Genet 2003;11631-54.
  • 38
    • 35348965192 scopus 로고    scopus 로고
    • Polymorphic variations in GSTM1, GSTT1, GSTP1, dopamine D2 and D3 receptors and their association with tardive dyskinesia in chronic schizophrenia
    • Lee HJ, Choi JE, Kang SG, Kim L. Polymorphic variations in GSTM1, GSTT1, GSTP1, dopamine D2 and D3 receptors and their association with tardive dyskinesia in chronic schizophrenia. Psychiatry Invest 2007;4(suppl 1):121.
    • (2007) Psychiatry Invest , vol.4 , Issue.SUPPL. 1 , pp. 121
    • Lee, H.J.1    Choi, J.E.2    Kang, S.G.3    Kim, L.4
  • 40
    • 0035094264 scopus 로고    scopus 로고
    • Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics? A new hypothesis
    • Kapur S, Seeman P. Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics? A new hypothesis. Am J Psychiatry 2001;158:360-369.
    • (2001) Am J Psychiatry , vol.158 , pp. 360-369
    • Kapur, S.1    Seeman, P.2
  • 41
    • 0030903368 scopus 로고    scopus 로고
    • Dopamine D3-receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients
    • Steen VM, Lovlie R, MacEwan T, McCreadie RG. Dopamine D3-receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients. Mol Psychiatry 1997;2:139-145.
    • (1997) Mol Psychiatry , vol.2 , pp. 139-145
    • Steen, V.M.1    Lovlie, R.2    MacEwan, T.3    McCreadie, R.G.4
  • 42
    • 0033046439 scopus 로고    scopus 로고
    • Genotypic association between the dopamine D3 receptor and tardive dyskinesia in chronic schizophrenia
    • Segman R, Neeman T, Heresco-Levy U, Finkel B, Karagichev L, Schlafman M, et al. Genotypic association between the dopamine D3 receptor and tardive dyskinesia in chronic schizophrenia. Mol Psychiatry 1999;4:247-253.
    • (1999) Mol Psychiatry , vol.4 , pp. 247-253
    • Segman, R.1    Neeman, T.2    Heresco-Levy, U.3    Finkel, B.4    Karagichev, L.5    Schlafman, M.6
  • 43
    • 0036283004 scopus 로고    scopus 로고
    • Pharmacogenetics of tardive dyskinesia: Combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism
    • Lerer B, Segman RH, Fangerau H, Daly AK, Basile VS, Cavallaro R, et al. Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism. Neuropsychopharmacology 2002;27:105-119.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 105-119
    • Lerer, B.1    Segman, R.H.2    Fangerau, H.3    Daly, A.K.4    Basile, V.S.5    Cavallaro, R.6
  • 45
    • 33645851672 scopus 로고    scopus 로고
    • Antipsychotic-induced tardive dyskinesia and the Ser9Gly polymorphism in the DRD3 gene: A metaanalysis
    • Bakker PR, van Harten PN, Van Os J. Antipsychotic-induced tardive dyskinesia and the Ser9Gly polymorphism in the DRD3 gene: a metaanalysis. Schizophr Res 2006;83:185-192.
    • (2006) Schizophr Res , vol.83 , pp. 185-192
    • Bakker, P.R.1    van Harten, P.N.2    Van Os, J.3
  • 46
    • 10644270840 scopus 로고    scopus 로고
    • Tardive dyskinesia and DRD2, DRD3, DRD4, 5-HT2A variants in schizophrenia: An association study with repeated assessment
    • Lattuada E, Cavallaro R, Serretti A, Lorenzi C, Smeraldi E. Tardive dyskinesia and DRD2, DRD3, DRD4, 5-HT2A variants in schizophrenia: an association study with repeated assessment. Int J Neuropsychopharmacol 2004;7:489-493.
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 489-493
    • Lattuada, E.1    Cavallaro, R.2    Serretti, A.3    Lorenzi, C.4    Smeraldi, E.5
  • 47
    • 10744222019 scopus 로고    scopus 로고
    • Association of dopaminergic and serotonergic genes with tardive dyskinesia in patients with chronic schizophrenia
    • Segman RH, Goltser T, Heresco-Levy U, Finkel B, Shalem R, Schlafman M, et al. Association of dopaminergic and serotonergic genes with tardive dyskinesia in patients with chronic schizophrenia. Pharmacogenomics J 2003;3:277-283.
    • (2003) Pharmacogenomics J , vol.3 , pp. 277-283
    • Segman, R.H.1    Goltser, T.2    Heresco-Levy, U.3    Finkel, B.4    Shalem, R.5    Schlafman, M.6
  • 48
    • 31344437482 scopus 로고    scopus 로고
    • Genetic susceptibility to tardive dyskinesia among schizophrenia subjects: IV. Role of dopaminergic pathway gene polymorphisms
    • Srivastava V, Varma PG, Prasad S, Semwal P, Nimgaonkar VL, Lerer B, et al. Genetic susceptibility to tardive dyskinesia among schizophrenia subjects: IV. Role of dopaminergic pathway gene polymorphisms. Pharmacogenet Genomics 2006;16:111-117.
    • (2006) Pharmacogenet Genomics , vol.16 , pp. 111-117
    • Srivastava, V.1    Varma, P.G.2    Prasad, S.3    Semwal, P.4    Nimgaonkar, V.L.5    Lerer, B.6
  • 49
    • 34347207196 scopus 로고    scopus 로고
    • No association between dopamine D4 receptor (DRD4) gene -521 CT polymorphism and tardive dyskinesia in schizophrenia
    • Lee HJ, Kang SG, Choi JE, Paik JW, Kim YK, Kim SH, et al. No association between dopamine D4 receptor (DRD4) gene -521 CT polymorphism and tardive dyskinesia in schizophrenia. Neuropsychobiology 2007;55:47-51.
    • (2007) Neuropsychobiology , vol.55 , pp. 47-51
    • Lee, H.J.1    Kang, S.G.2    Choi, J.E.3    Paik, J.W.4    Kim, Y.K.5    Kim, S.H.6
  • 50
    • 3142777760 scopus 로고    scopus 로고
    • Polymorphisms of dopamine degradation enzyme (COMT and MAO) genes and tardive dyskinesia in patients with schizophrenia
    • Matsumoto C, Shinkai T, Hori H, Ohmori O, Nakamura J. Polymorphisms of dopamine degradation enzyme (COMT and MAO) genes and tardive dyskinesia in patients with schizophrenia. Psychiatry Res 2004;127:1-7.
    • (2004) Psychiatry Res , vol.127 , pp. 1-7
    • Matsumoto, C.1    Shinkai, T.2    Hori, H.3    Ohmori, O.4    Nakamura, J.5
  • 51
    • 0035878579 scopus 로고    scopus 로고
    • Susceptibility to neuroleptic-induced tardive dyskinesia and the T102C polymorphism in the serotonin type 2A receptor
    • Tan EC, Chong SA, Mahendran R, Dong F, Tan CH. Susceptibility to neuroleptic-induced tardive dyskinesia and the T102C polymorphism in the serotonin type 2A receptor. Biol Psychiatry 2001;50:144-147.
    • (2001) Biol Psychiatry , vol.50 , pp. 144-147
    • Tan, E.C.1    Chong, S.A.2    Mahendran, R.3    Dong, F.4    Tan, C.H.5
  • 52
    • 17744392199 scopus 로고    scopus 로고
    • Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia
    • Segman RH, Heresco-Levy U, Finkel B, Goltser T, Shalem R, Schlafman M, et al. Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia. Mol Psychiatry 2001;6:225-229.
    • (2001) Mol Psychiatry , vol.6 , pp. 225-229
    • Segman, R.H.1    Heresco-Levy, U.2    Finkel, B.3    Goltser, T.4    Shalem, R.5    Schlafman, M.6
  • 53
    • 0037628614 scopus 로고    scopus 로고
    • Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene
    • Herken H, Erdal ME, Boke O, Savas HA. Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene. Eur Psychiatry 2003;18:77-81.
    • (2003) Eur Psychiatry , vol.18 , pp. 77-81
    • Herken, H.1    Erdal, M.E.2    Boke, O.3    Savas, H.A.4
  • 54
    • 0035116425 scopus 로고    scopus 로고
    • Lack of association between serotonin-2A receptor gene (HTR2A) polymorphisms and tardive dyskinesia in schizophrenia
    • Basile VS, Ozdemir V, Masellis M, Meltzer HY, Lieberman JA, Potkin SG, et al. Lack of association between serotonin-2A receptor gene (HTR2A) polymorphisms and tardive dyskinesia in schizophrenia. Mol Psychiatry 2001;6:230-234.
    • (2001) Mol Psychiatry , vol.6 , pp. 230-234
    • Basile, V.S.1    Ozdemir, V.2    Masellis, M.3    Meltzer, H.Y.4    Lieberman, J.A.5    Potkin, S.G.6
  • 55
    • 24144503437 scopus 로고    scopus 로고
    • Serotonin receptor gene polymorphisms and their association with tardive dyskinesia among schizophrenia patients from North India
    • Deshpande SN, Vanna PG, Semwal P, Rao AR, Bhatia T, Nimgaonkar VL, et al. Serotonin receptor gene polymorphisms and their association with tardive dyskinesia among schizophrenia patients from North India. Psychiatr Genet 2005;15:157-158.
    • (2005) Psychiatr Genet , vol.15 , pp. 157-158
    • Deshpande, S.N.1    Vanna, P.G.2    Semwal, P.3    Rao, A.R.4    Bhatia, T.5    Nimgaonkar, V.L.6
  • 56
    • 22344436588 scopus 로고    scopus 로고
    • Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial subtype
    • Lerer B, Segman RH, Tan EC, Basile VS, Cavallaro R, Aschauer HN, et al. Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial subtype. Int J Neuropsychopharmacol 2005;8:411-425.
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 411-425
    • Lerer, B.1    Segman, R.H.2    Tan, E.C.3    Basile, V.S.4    Cavallaro, R.5    Aschauer, H.N.6
  • 57
    • 0036371340 scopus 로고    scopus 로고
    • Association of a polymorphism in the promoter region of the serotonin 5-HT2C receptor gene with tardive dyskinesia in patients with schizophrenia
    • Zhang ZJ, Zhang XB, Sha WW, Zhang XB, Reynolds GP. Association of a polymorphism in the promoter region of the serotonin 5-HT2C receptor gene with tardive dyskinesia in patients with schizophrenia. Mol Psychiatry 2002;7:670-671.
    • (2002) Mol Psychiatry , vol.7 , pp. 670-671
    • Zhang, Z.J.1    Zhang, X.B.2    Sha, W.W.3    Zhang, X.B.4    Reynolds, G.P.5
  • 58
    • 0030738648 scopus 로고    scopus 로고
    • Efficacy and side-effects of clozapine not associated with variation in the 5-HT2C receptor
    • Rietschel M, Naber D, Fimmers R, Moller HJ, Propping P, Nothen MM. Efficacy and side-effects of clozapine not associated with variation in the 5-HT2C receptor. Neuroreport 1997;8:1999-2003.
    • (1997) Neuroreport , vol.8 , pp. 1999-2003
    • Rietschel, M.1    Naber, D.2    Fimmers, R.3    Moller, H.J.4    Propping, P.5    Nothen, M.M.6
  • 59
    • 0036606013 scopus 로고    scopus 로고
    • Genetic association analysis of 5-HT (6) receptor gene polymorphism (267C/T) with tardive dyskinesia
    • Ohmori O, Shinkai T, Hori H, Nakamura J. Genetic association analysis of 5-HT (6) receptor gene polymorphism (267C/T) with tardive dyskinesia. Psychiatry Res 2002;110:97-102.
    • (2002) Psychiatry Res , vol.110 , pp. 97-102
    • Ohmori, O.1    Shinkai, T.2    Hori, H.3    Nakamura, J.4
  • 60
    • 0034606264 scopus 로고    scopus 로고
    • Tardive dyskinesia is not associated with the serotonin gene polymorphism (5-HTTLPR) in Chinese
    • Chong SA, Tan EC, Tan CH, Mahendren R, Tay AH, Chua HC. Tardive dyskinesia is not associated with the serotonin gene polymorphism (5-HTTLPR) in Chinese. Am J Med Genet 2000;96:712-715.
    • (2000) Am J Med Genet , vol.96 , pp. 712-715
    • Chong, S.A.1    Tan, E.C.2    Tan, C.H.3    Mahendren, R.4    Tay, A.H.5    Chua, H.C.6
  • 61
    • 0031844208 scopus 로고    scopus 로고
    • Induction of reactive oxygen species in neurons by haloperidol
    • Sagara Y. Induction of reactive oxygen species in neurons by haloperidol. J Neurochem 1998;71:1002-1012.
    • (1998) J Neurochem , vol.71 , pp. 1002-1012
    • Sagara, Y.1
  • 62
    • 0025125631 scopus 로고
    • Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia
    • Lohr JB, Kuczenski R, Bracha HS, Moir M, Jeste DV. Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia. Biol Psychiatry 1990;28:535-539.
    • (1990) Biol Psychiatry , vol.28 , pp. 535-539
    • Lohr, J.B.1    Kuczenski, R.2    Bracha, H.S.3    Moir, M.4    Jeste, D.V.5
  • 63
    • 0031695231 scopus 로고    scopus 로고
    • Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia
    • Tsai G, Goff DC, Chang RW, Flood J, Baer L, Coyle JT. Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia. Am J Psychiatry 1998;155:1207-1213.
    • (1998) Am J Psychiatry , vol.155 , pp. 1207-1213
    • Tsai, G.1    Goff, D.C.2    Chang, R.W.3    Flood, J.4    Baer, L.5    Coyle, J.T.6
  • 66
    • 0036019989 scopus 로고    scopus 로고
    • The increased activity of plasma manganese superoxide dismutase in tardive dyskinesia is unrelated to the Ala-9Val polymorphism
    • Zhang Z, Zhang X, Hou G, Sha W, Reynolds GP. The increased activity of plasma manganese superoxide dismutase in tardive dyskinesia is unrelated to the Ala-9Val polymorphism. J Psychiatr Res 2002;36:317-324.
    • (2002) J Psychiatr Res , vol.36 , pp. 317-324
    • Zhang, Z.1    Zhang, X.2    Hou, G.3    Sha, W.4    Reynolds, G.P.5
  • 67
    • 4644307783 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 polymorphism may contribute to schizophrenia in the Korean population
    • Pae CU, Yu HS, Kim JJ, Kim W, Lee CU, Lee SJ, et al. Glutathione S-transferase M1 polymorphism may contribute to schizophrenia in the Korean population. Psychiatr Genet 2004;14:147-150.
    • (2004) Psychiatr Genet , vol.14 , pp. 147-150
    • Pae, C.U.1    Yu, H.S.2    Kim, J.J.3    Kim, W.4    Lee, C.U.5    Lee, S.J.6
  • 68
    • 33645035694 scopus 로고    scopus 로고
    • Genetic association analysis of the glutathione peroxidase (GP-X1) gene polymorphism (Pro197Leu) with tardive dyskinesia
    • Shinkai T, Müller DJ, De Luca V, Shaikh S, Matsumoto C, Hwang R, et al. Genetic association analysis of the glutathione peroxidase (GP-X1) gene polymorphism (Pro197Leu) with tardive dyskinesia. Psychiatry Res 2006;141:123-128.
    • (2006) Psychiatry Res , vol.141 , pp. 123-128
    • Shinkai, T.1    Müller, D.J.2    De Luca, V.3    Shaikh, S.4    Matsumoto, C.5    Hwang, R.6
  • 69
    • 2342523372 scopus 로고    scopus 로고
    • Genetic association analysis of neuronal nitric oxide synthase gene polymorphism with tardive dyskinesia
    • Shinkai T, Ohmori O, Matsumoto C, Hori H, Kennedy JL, Nakamura J. Genetic association analysis of neuronal nitric oxide synthase gene polymorphism with tardive dyskinesia. Neuromolecular Med 2004;5:163-170.
    • (2004) Neuromolecular Med , vol.5 , pp. 163-170
    • Shinkai, T.1    Ohmori, O.2    Matsumoto, C.3    Hori, H.4    Kennedy, J.L.5    Nakamura, J.6
  • 70
    • 33745229249 scopus 로고    scopus 로고
    • No association between a functional NAD(P)H: Quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia
    • Hori H, Shinkai I, Matsumoto C, Ohmori O, Nakamura J. No association between a functional NAD(P)H: quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia. Neuromolecular Med 2006;8:375-380.
    • (2006) Neuromolecular Med , vol.8 , pp. 375-380
    • Hori, H.1    Shinkai, I.2    Matsumoto, C.3    Ohmori, O.4    Nakamura, J.5
  • 71
    • 10644226033 scopus 로고    scopus 로고
    • Quinone oxidoreduetase (NQO1) gene polymorphism (609C/T) may be associated with tardive dyskinesia, but not with the development of schizophrenia
    • Pae CU, Yu HS, Kim JJ, Lee CU, Lee SJ, Jun TY, et al. Quinone oxidoreduetase (NQO1) gene polymorphism (609C/T) may be associated with tardive dyskinesia, but not with the development of schizophrenia. Int J Neuropsychopharmacol 2004;7:495-500.
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 495-500
    • Pae, C.U.1    Yu, H.S.2    Kim, J.J.3    Lee, C.U.4    Lee, S.J.5    Jun, T.Y.6
  • 72
    • 25444490459 scopus 로고    scopus 로고
    • Polymorphic variations in GSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 and D3 receptors and their association with tardive dyskinesia in severe mental illness
    • de Leon J, Susce MT, Pan RM, Koch WH, Wedlund PJ. Polymorphic variations in GSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 and D3 receptors and their association with tardive dyskinesia in severe mental illness. J Clin Psychopharmacol 2005;25:448-456.
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 448-456
    • de Leon, J.1    Susce, M.T.2    Pan, R.M.3    Koch, W.H.4    Wedlund, P.J.5
  • 73
    • 33644876960 scopus 로고    scopus 로고
    • A novel brain-targeted antioxidant (AD4) attenuates haloperidol-induced abnormal movement in rats: Implications for tardive dyskinesia
    • Sadan O, Bahat-Stromza M, Gilgun-Sherki Y, Atlas D, Melamed E, Offen D. A novel brain-targeted antioxidant (AD4) attenuates haloperidol-induced abnormal movement in rats: implications for tardive dyskinesia. Clin Neuropharmacol 2005;28:285-288.
    • (2005) Clin Neuropharmacol , vol.28 , pp. 285-288
    • Sadan, O.1    Bahat-Stromza, M.2    Gilgun-Sherki, Y.3    Atlas, D.4    Melamed, E.5    Offen, D.6
  • 74
    • 34247107021 scopus 로고    scopus 로고
    • Genetic susceptibility to Tardive Dyskinesia in chronic schizophrenia subjects: Role of oxidative stress pathway genes
    • Thelma BK, Tiwari AK, Deshpande SN, Lerer B, Nimgaonkar VL. Genetic susceptibility to Tardive Dyskinesia in chronic schizophrenia subjects: role of oxidative stress pathway genes. Schizophr Res 2007;92278-279.
    • (2007) Schizophr Res , pp. 92278-92279
    • Thelma, B.K.1    Tiwari, A.K.2    Deshpande, S.N.3    Lerer, B.4    Nimgaonkar, V.L.5
  • 75
    • 0029049844 scopus 로고
    • Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia
    • Arthur H, Dahl ML, Siwers B, Sjoqvist F. Polymorphic drug metabolism in schizophrenic patients with tardive dyskinesia. J Clin Psychopharmacol 1995;15:211-216.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 211-216
    • Arthur, H.1    Dahl, M.L.2    Siwers, B.3    Sjoqvist, F.4
  • 76
    • 33644819392 scopus 로고    scopus 로고
    • Association of CYP2D6 and CYP1A2 gene polymorphism with tardive dyskinesia in Chinese schizophrenic patients
    • Fu Y, Fan CH, Deng HH, Hu SH, Lv DP, Li LH, et al. Association of CYP2D6 and CYP1A2 gene polymorphism with tardive dyskinesia in Chinese schizophrenic patients. Acta Pharmacol Sin 2006;27:328-332.
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 328-332
    • Fu, Y.1    Fan, C.H.2    Deng, H.H.3    Hu, S.H.4    Lv, D.P.5    Li, L.H.6
  • 77
  • 78
    • 2342562985 scopus 로고    scopus 로고
    • Cytochrome P-450 2D6*10 C188 T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients
    • Liou YJ, Wang YC, Bai YM, Lin CC, Yu SC, Liao DL, et al. Cytochrome P-450 2D6*10 C188 T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients. Neuropsychobiology 2004;49:167-173.
    • (2004) Neuropsychobiology , vol.49 , pp. 167-173
    • Liou, Y.J.1    Wang, Y.C.2    Bai, Y.M.3    Lin, C.C.4    Yu, S.C.5    Liao, D.L.6
  • 79
    • 0033939932 scopus 로고    scopus 로고
    • A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: Association with tardive dyskinesia in schizophrenia
    • Basile VS, Ozdemir V, Masellis M, Walker ML, Meltzer HY, Lieberman JA, et al. A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia. Mol Psychiatry 2000;5:410-417.
    • (2000) Mol Psychiatry , vol.5 , pp. 410-417
    • Basile, V.S.1    Ozdemir, V.2    Masellis, M.3    Walker, M.L.4    Meltzer, H.Y.5    Lieberman, J.A.6
  • 80
    • 16844384063 scopus 로고    scopus 로고
    • Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: III. Lack of association of CYP3A4 and CYP2D6 gene polymorphisms
    • Tiwari AK, Deshpande SN, Rao AR, Bhatia T, Lerer B, Nimgaonkar VL, et al. Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: III. Lack of association of CYP3A4 and CYP2D6 gene polymorphisms. Schizophr Res 2005;75:21-26.
    • (2005) Schizophr Res , vol.75 , pp. 21-26
    • Tiwari, A.K.1    Deshpande, S.N.2    Rao, A.R.3    Bhatia, T.4    Lerer, B.5    Nimgaonkar, V.L.6
  • 81
    • 25444490459 scopus 로고    scopus 로고
    • Polymorphic variations in GSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 and D3 receptors and their association with tardive dyskinesia in severe mental illness
    • de Leon J, Susce MT, Pan RM, Koch WH, Wedlund PJ. Polymorphic variations in GSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 and D3 receptors and their association with tardive dyskinesia in severe mental illness. J Clin Psychopharmacol 2005;25:448-456.
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 448-456
    • de Leon, J.1    Susce, M.T.2    Pan, R.M.3    Koch, W.H.4    Wedlund, P.J.5
  • 82
    • 35348957329 scopus 로고    scopus 로고
    • No evidence for an association between G protein beta3 subunit gene C825T polymorphism and tardive dyskinesia in schizophrenia
    • in press
    • Lee HJ, Kang SG, Paik JW, Lee MS, Cho BH, Park YM, et al. No evidence for an association between G protein beta3 subunit gene C825T polymorphism and tardive dyskinesia in schizophrenia. Hum Psychopharmacol 2007, in press.
    • (2007) Hum Psychopharmacol
    • Lee, H.J.1    Kang, S.G.2    Paik, J.W.3    Lee, M.S.4    Cho, B.H.5    Park, Y.M.6
  • 84
    • 0034121256 scopus 로고    scopus 로고
    • Atypical antipsychotics and weight gain - a systematic review
    • Taylor DM, McAskill R. Atypical antipsychotics and weight gain - a systematic review. Acta Psychiatr Scand 2000;101:416-432.
    • (2000) Acta Psychiatr Scand , vol.101 , pp. 416-432
    • Taylor, D.M.1    McAskill, R.2
  • 85
    • 4644354707 scopus 로고    scopus 로고
    • Atypical antipsychotics and metabolic dysregulation: Evaluating the risk/benefit equation and improving the standard of care
    • Nasrallah HA, Newcomer JW. Atypical antipsychotics and metabolic dysregulation: evaluating the risk/benefit equation and improving the standard of care. J Clin Psychopharmacol 200424 (5 suppl 1):7-14.
    • (2004) J Clin Psychopharmacol , vol.24 , Issue.5 SUPPL. 1 , pp. 7-14
    • Nasrallah, H.A.1    Newcomer, J.W.2
  • 86
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 2002;359:2086-2087.
    • (2002) Lancet , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 87
    • 0034103054 scopus 로고    scopus 로고
    • Identification of polymorphic loci in the promoter region of the serotonin 5-HT2C receptor gene and their association with obesity and type II diabetes
    • Yuan X, Yamada K, Ishiyama-Shigemoto S, Koyama W, Nonaka K. Identification of polymorphic loci in the promoter region of the serotonin 5-HT2C receptor gene and their association with obesity and type II diabetes. Diabetologia 2000;43:373-376.
    • (2000) Diabetologia , vol.43 , pp. 373-376
    • Yuan, X.1    Yamada, K.2    Ishiyama-Shigemoto, S.3    Koyama, W.4    Nonaka, K.5
  • 88
    • 0034785813 scopus 로고    scopus 로고
    • Genetic dissection of atypical antipsychotic-induced weight gain: Novel preliminary data on the pharmacogenetic puzzle
    • Basile VS, Masellis M, McIntyre RS, Meltzer HY, Lieberman JA, Kennedy JL. Genetic dissection of atypical antipsychotic-induced weight gain: novel preliminary data on the pharmacogenetic puzzle. J Clin Psychiatry 2001;62(suppl 23):45-66.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 23 , pp. 45-66
    • Basile, V.S.1    Masellis, M.2    McIntyre, R.S.3    Meltzer, H.Y.4    Lieberman, J.A.5    Kennedy, J.L.6
  • 89
    • 2342525335 scopus 로고    scopus 로고
    • Association of -2548G/A functional polymorphism in the promoter region of leptin gene with antipsychotic agent-induced weight gain
    • Zhang ZJ, Yao ZJ, Mou XD, Chen JF, Zhuk RX, Liu W, et al. Association of -2548G/A functional polymorphism in the promoter region of leptin gene with antipsychotic agent-induced weight gain. Zhonghua Yi Xue Za Zhi 2003;83:2119-2123.
    • (2003) Zhonghua Yi Xue Za Zhi , vol.83 , pp. 2119-2123
    • Zhang, Z.J.1    Yao, Z.J.2    Mou, X.D.3    Chen, J.F.4    Zhuk, R.X.5    Liu, W.6
  • 90
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, San L. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics 2005;15:195-200.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 91
    • 0038474172 scopus 로고    scopus 로고
    • Polymorphism of the promoter region of the serotonin 5-HT (2C) receptor gene and clozapine-induced weight gain
    • Reynolds GP, Zhang ZJ, Zhang XB. Polymorphism of the promoter region of the serotonin 5-HT (2C) receptor gene and clozapine-induced weight gain. Am J Psychiatry 2003;160:677-679.
    • (2003) Am J Psychiatry , vol.160 , pp. 677-679
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 92
    • 14844322355 scopus 로고    scopus 로고
    • Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain
    • Buckland PR, Hoogendoorn B, Guy CA, Smith SK, Coleman SL, O'donovan MC. Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain. Am J Psychiatry 2005;162:613-615.
    • (2005) Am J Psychiatry , vol.162 , pp. 613-615
    • Buckland, P.R.1    Hoogendoorn, B.2    Guy, C.A.3    Smith, S.K.4    Coleman, S.L.5    O'donovan, M.C.6
  • 94
    • 0035052252 scopus 로고    scopus 로고
    • Genetic variants of the serotonin system and weight change during clozapine treatment
    • Hong CJ, Lin CH, Yu YW, Yang KH, Tsai SJ. Genetic variants of the serotonin system and weight change during clozapine treatment. Pharmacogenetics 2001;11:265-268.
    • (2001) Pharmacogenetics , vol.11 , pp. 265-268
    • Hong, C.J.1    Lin, C.H.2    Yu, Y.W.3    Yang, K.H.4    Tsai, S.J.5
  • 95
    • 0037202751 scopus 로고    scopus 로고
    • 759C/T genetic variation of 5HT (2C) receptor and clozapine-induced weight gain
    • Tsai SJ, Hong CJ, Yu YW, Lin CH. 759C/T genetic variation of 5HT (2C) receptor and clozapine-induced weight gain. Lancet 2002;360:1790.
    • (2002) Lancet , vol.360 , pp. 1790
    • Tsai, S.J.1    Hong, C.J.2    Yu, Y.W.3    Lin, C.H.4
  • 96
    • 0037202751 scopus 로고    scopus 로고
    • 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain
    • Basile VS, Masellis M, De Luca V, Meltzer HY, Kennedy JL. 759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain. Lancet 2002;360:1790-1791.
    • (2002) Lancet , vol.360 , pp. 1790-1791
    • Basile, V.S.1    Masellis, M.2    De Luca, V.3    Meltzer, H.Y.4    Kennedy, J.L.5
  • 97
    • 4644225416 scopus 로고    scopus 로고
    • Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals
    • Theisen FM, Hinney A, Bromel T, Heinzel-Gutenbrunner M, Martin M, Krieg JC, et al. Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals. Psychiatr Genet 2004;14:139-142.
    • (2004) Psychiatr Genet , vol.14 , pp. 139-142
    • Theisen, F.M.1    Hinney, A.2    Bromel, T.3    Heinzel-Gutenbrunner, M.4    Martin, M.5    Krieg, J.C.6
  • 99
    • 33947512695 scopus 로고    scopus 로고
    • 759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment
    • Ryu S, Cho EY, Park T, Oh S, Jang WS, Kim SK, et al. -759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment. Prog Neuropsychopharmacol Biol Psychiatry 2007;31:673-677.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 673-677
    • Ryu, S.1    Cho, E.Y.2    Park, T.3    Oh, S.4    Jang, W.S.5    Kim, S.K.6
  • 102
    • 0030032754 scopus 로고    scopus 로고
    • Genomic structure and promoter analysis of the human obese gene
    • Gong DW, Bi S, Pratley RE, Weintraub BD. Genomic structure and promoter analysis of the human obese gene. J Biol Chem 1996;271:3971-3974.
    • (1996) J Biol Chem , vol.271 , pp. 3971-3974
    • Gong, D.W.1    Bi, S.2    Pratley, R.E.3    Weintraub, B.D.4
  • 103
    • 0034527931 scopus 로고    scopus 로고
    • Association of the G-2548A polymorphism in the 50 region of the LEP gene with overweight
    • Mammes O, Betoulle D, Aubert R, Herbeth B, Siest G, Fumeron F. Association of the G-2548A polymorphism in the 50 region of the LEP gene with overweight. Ann Hum Genet 2000;64:391-394.
    • (2000) Ann Hum Genet , vol.64 , pp. 391-394
    • Mammes, O.1    Betoulle, D.2    Aubert, R.3    Herbeth, B.4    Siest, G.5    Fumeron, F.6
  • 104
    • 0032871802 scopus 로고    scopus 로고
    • Sequence variants in the 5′ flanking region of the leptin gene are associated with obesity in women
    • Li WD, Reed DR, Lee JH, Xu W, Kilker RL, Sodam BR, et al. Sequence variants in the 5′ flanking region of the leptin gene are associated with obesity in women. Ann Hum Genet 1999;63:227-234.
    • (1999) Ann Hum Genet , vol.63 , pp. 227-234
    • Li, W.D.1    Reed, D.R.2    Lee, J.H.3    Xu, W.4    Kilker, R.L.5    Sodam, B.R.6
  • 105
    • 33748194234 scopus 로고    scopus 로고
    • G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines
    • Wang TN, Huang MC, Chang WT, Ko AM, Tsai EM, Liu CS, et al. G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines. Obesity 2006;14:183-187.
    • (2006) Obesity , vol.14 , pp. 183-187
    • Wang, T.N.1    Huang, M.C.2    Chang, W.T.3    Ko, A.M.4    Tsai, E.M.5    Liu, C.S.6
  • 106
    • 38349027801 scopus 로고    scopus 로고
    • Association Study of-2548A/G Polymorphism of Leptin Gene with Antipsyhotics-Induced Weight Gain
    • Ryu SH, Jang WS, Cho EY, Kim SK, Lee DS, Hong KS. Association Study of-2548A/G Polymorphism of Leptin Gene with Antipsyhotics-Induced Weight Gain. Korean J Psychopharmacol 2006;17: 23-428.
    • (2006) Korean J Psychopharmacol , vol.17 , pp. 23-428
    • Ryu, S.H.1    Jang, W.S.2    Cho, E.Y.3    Kim, S.K.4    Lee, D.S.5    Hong, K.S.6
  • 108
    • 25144477595 scopus 로고    scopus 로고
    • Polymorphism of the adrenergic receptor alpha 2a -129IC>G genetic variation and clozapine-induced weight gain
    • Wang YC, Bai YM, Chen JY, Lin CC, Lai IC, Liou YJ. Polymorphism of the adrenergic receptor alpha 2a -129IC>G genetic variation and clozapine-induced weight gain. J Neural Transm 2005;112:1463-1468.
    • (2005) J Neural Transm , vol.112 , pp. 1463-1468
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3    Lin, C.C.4    Lai, I.C.5    Liou, Y.J.6
  • 109
    • 33745013199 scopus 로고    scopus 로고
    • Weight gain associated with the alpha2a-adrencrgic receptor -1,291 C/G polymorphism and olanzapine treatment
    • Park YM, Chung YC, Lee SH, Lee KJ, Kim H, Byun YC, et al. Weight gain associated with the alpha2a-adrencrgic receptor -1,291 C/G polymorphism and olanzapine treatment. Am J Med Genet B Neuropsychiatr Genet 2006;141:394-397.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 , pp. 394-397
    • Park, Y.M.1    Chung, Y.C.2    Lee, S.H.3    Lee, K.J.4    Kim, H.5    Byun, Y.C.6
  • 110
    • 2642586378 scopus 로고    scopus 로고
    • Association study of adrenergic beta3 receptor (Trp64Arg) and G-protein beta3 subunit gene (C825T) polymorphisms and weight change during clozapine treatment
    • Tsai SJ, Yu YW, Lin CH, Wang YC, Chen JY, Hong CJ. Association study of adrenergic beta3 receptor (Trp64Arg) and G-protein beta3 subunit gene (C825T) polymorphisms and weight change during clozapine treatment. Neuropsychobiology 2004;50:37-40.
    • (2004) Neuropsychobiology , vol.50 , pp. 37-40
    • Tsai, S.J.1    Yu, Y.W.2    Lin, C.H.3    Wang, Y.C.4    Chen, J.Y.5    Hong, C.J.6
  • 111
    • 25144497419 scopus 로고    scopus 로고
    • C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population
    • Wang YC, Bai YM, Chen JY, Lin CC, Lai IC, Liou YJ. C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population. Pharmacogenet Genomics 2005;15:743-748.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 743-748
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3    Lin, C.C.4    Lai, I.C.5    Liou, Y.J.6
  • 112
    • 32044467124 scopus 로고    scopus 로고
    • Pilot study of the G-protein beta3 subunit gene (C825T) polymorphism and clinical response to olanzapine or olanzapine-related weight gain in persons with schizophrenia
    • Bishop JR, Ellingrod VL, Moline J, Miller D. Pilot study of the G-protein beta3 subunit gene (C825T) polymorphism and clinical response to olanzapine or olanzapine-related weight gain in persons with schizophrenia. Med Sci Monit 2006;12:BR47-BR50.
    • (2006) Med Sci Monit , vol.12
    • Bishop, J.R.1    Ellingrod, V.L.2    Moline, J.3    Miller, D.4
  • 113
    • 35349018499 scopus 로고    scopus 로고
    • Park YM, Lee HJ, Chung YC, Lee SH, Kang SG, Choi JE, et al. No evidence of association between G-protein beta subunit gene polymorphism and olanzapine-induce weight gain, in submission
    • Park YM, Lee HJ, Chung YC, Lee SH, Kang SG, Choi JE, et al. No evidence of association between G-protein beta subunit gene polymorphism and olanzapine-induce weight gain, in submission.
  • 114
    • 11244270333 scopus 로고    scopus 로고
    • A genome wide linkage study of obesity as secondary effect of antipsychotics in multigenerational families of eastern Quebec affected by psychoses
    • Chagnon YC, Merette C, Bouchard RH, Emond C, Roy MA, Maziade M. A genome wide linkage study of obesity as secondary effect of antipsychotics in multigenerational families of eastern Quebec affected by psychoses. Mol Psychiatry 2004;9:1067-1074.
    • (2004) Mol Psychiatry , vol.9 , pp. 1067-1074
    • Chagnon, Y.C.1    Merette, C.2    Bouchard, R.H.3    Emond, C.4    Roy, M.A.5    Maziade, M.6
  • 116
    • 0038154906 scopus 로고    scopus 로고
    • Restless legs syndrome (RLS), a common disorder rarely diagnosed in Europe or USA: The REST (RLS epidemiology, symptoms and treatment) study in primary care
    • Allen R, Hening WA, Montplaiser J, Walters AS, Brown T, Myers A. Restless legs syndrome (RLS), a common disorder rarely diagnosed in Europe or USA: the REST (RLS epidemiology, symptoms and treatment) study in primary care. Mov Disord 2002;17:S240.
    • (2002) Mov Disord , vol.17
    • Allen, R.1    Hening, W.A.2    Montplaiser, J.3    Walters, A.S.4    Brown, T.5    Myers, A.6
  • 117
    • 21244442618 scopus 로고    scopus 로고
    • Prevalence of restless legs syndrome and associated factors in the Korean adult population: The Korean Health and Genome Study
    • Kim JY, Choi C, Shin K, Yi H, Park M, Cho N, et al. Prevalence of restless legs syndrome and associated factors in the Korean adult population: the Korean Health and Genome Study. Psychiatry and Clin Neurosci 2005;59:350-353.
    • (2005) Psychiatry and Clin Neurosci , vol.59 , pp. 350-353
    • Kim, J.Y.1    Choi, C.2    Shin, K.3    Yi, H.4    Park, M.5    Cho, N.6
  • 120
    • 2342527865 scopus 로고    scopus 로고
    • Genomewide linkage scan identifies a novel susceptibility locus for RLS on chromosome 9p
    • Chen S, Ondo WG, Rao S, Li L, Chen Q, Wang Q. Genomewide linkage scan identifies a novel susceptibility locus for RLS on chromosome 9p. Am J Hum Genet 2004;74:876-889.
    • (2004) Am J Hum Genet , vol.74 , pp. 876-889
    • Chen, S.1    Ondo, W.G.2    Rao, S.3    Li, L.4    Chen, Q.5    Wang, Q.6
  • 121
  • 122
    • 20144387708 scopus 로고    scopus 로고
    • Restless legs syndrome: Confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity
    • Desautels A, Turecki G, Montplaisir J, Xiong L, Walters AS, Ehrenberg BL, et al. Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity. Arch Neurol 2005;62:591-596.
    • (2005) Arch Neurol , vol.62 , pp. 591-596
    • Desautels, A.1    Turecki, G.2    Montplaisir, J.3    Xiong, L.4    Walters, A.S.5    Ehrenberg, B.L.6
  • 124
    • 33749005651 scopus 로고    scopus 로고
    • Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolate
    • Pichler I, Marroni F, Volpato CB, Gusella JF, Klein C, Casari G, et al. Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolate. Am J Hum Genet 2006;79:716-723.
    • (2006) Am J Hum Genet , vol.79 , pp. 716-723
    • Pichler, I.1    Marroni, F.2    Volpato, C.B.3    Gusella, J.F.4    Klein, C.5    Casari, G.6
  • 127
    • 0037162352 scopus 로고    scopus 로고
    • Evidence for a genetic association between monoamine oxidase A and restless legs syndrome
    • Desautels A, Turecki G, Montplaisir J, Briscbois K, Sequeira A, Adam B, et al. Evidence for a genetic association between monoamine oxidase A and restless legs syndrome. Neurology 2002;59:215-219.
    • (2002) Neurology , vol.59 , pp. 215-219
    • Desautels, A.1    Turecki, G.2    Montplaisir, J.3    Briscbois, K.4    Sequeira, A.5    Adam, B.6
  • 128
    • 36248996970 scopus 로고    scopus 로고
    • Possible association between G-protein beta3 C825T polymorphism and antipsychotic-induced restless legs syndrome in schizophrenia
    • in press
    • Kang SG, Lee HJ, Choi JE, Park JH, Lee SS, Han C, et al. Possible association between G-protein beta3 C825T polymorphism and antipsychotic-induced restless legs syndrome in schizophrenia. Acta Neuropsychiatrica, in press.
    • Acta Neuropsychiatrica
    • Kang, S.G.1    Lee, H.J.2    Choi, J.E.3    Park, J.H.4    Lee, S.S.5    Han, C.6
  • 130
    • 0033288769 scopus 로고    scopus 로고
    • Active monitoring of 12 760 clozapine recipients in the UK and Ireland. Beyond pharmacovigilance
    • Munro J, O'Sullivan D, Andrews C, Arana A, Mortimer A, Kerwin R. Active monitoring of 12 760 clozapine recipients in the UK and Ireland. Beyond pharmacovigilance. Br J Psychiatry 1999;175:576-580.
    • (1999) Br J Psychiatry , vol.175 , pp. 576-580
    • Munro, J.1    O'Sullivan, D.2    Andrews, C.3    Arana, A.4    Mortimer, A.5    Kerwin, R.6
  • 132
    • 0031965777 scopus 로고    scopus 로고
    • HLA-B38 and clozapine-induced agranulotycosis in Israeli Jewish schizophrenic patients
    • Valevski A, Klein T, Gazit E, Meged S, Stein D, Elizur A, et al. HLA-B38 and clozapine-induced agranulotycosis in Israeli Jewish schizophrenic patients. Eur J Immunogenet 1998;25:11-13.
    • (1998) Eur J Immunogenet , vol.25 , pp. 11-13
    • Valevski, A.1    Klein, T.2    Gazit, E.3    Meged, S.4    Stein, D.5    Elizur, A.6
  • 133
    • 0035175936 scopus 로고    scopus 로고
    • Genetic determinants of clozapine-induced agranulocytosis: Recent results of HLA subtyping in a non-Jewish Caucasian sample
    • Dettling M, Cascorbi I. Genetic determinants of clozapine-induced agranulocytosis: recent results of HLA subtyping in a non-Jewish Caucasian sample. Arch Gen Psychiatry 2001;58:93-94.
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 93-94
    • Dettling, M.1    Cascorbi, I.2
  • 136
    • 0030992688 scopus 로고    scopus 로고
    • Tumor necrosis factor constellation polymorphism and clozapin-induced agranulocytosis in two different ethnic groups
    • Turbay D, Lieberman J, Alper CA, Delgado JC, Corzo D, Yunis JJ, et al. Tumor necrosis factor constellation polymorphism and clozapin-induced agranulocytosis in two different ethnic groups. Blood 1997;89:4167-4174.
    • (1997) Blood , vol.89 , pp. 4167-4174
    • Turbay, D.1    Lieberman, J.2    Alper, C.A.3    Delgado, J.C.4    Corzo, D.5    Yunis, J.J.6
  • 137
    • 22244471085 scopus 로고    scopus 로고
    • Genetics and epigenetics in major psychiatric disorders: Dilemmas, achievements, applications, and future scope
    • Abdolmaleky HM, Thiagalingam S, Wilcox M. Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope. Am J Pharmacogenomics 2005;5:149-160.
    • (2005) Am J Pharmacogenomics , vol.5 , pp. 149-160
    • Abdolmaleky, H.M.1    Thiagalingam, S.2    Wilcox, M.3
  • 138
    • 2342460272 scopus 로고    scopus 로고
    • Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene
    • Flomen R, Knight J, Sham P, Kerwin R, Makoff A. Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene. Nucleic Acids Res 2004;32:2113-2122.
    • (2004) Nucleic Acids Res , vol.32 , pp. 2113-2122
    • Flomen, R.1    Knight, J.2    Sham, P.3    Kerwin, R.4    Makoff, A.5
  • 139
    • 33745752370 scopus 로고    scopus 로고
    • Epigenetics and twins: Three variations on the theme
    • Petronis A. Epigenetics and twins: three variations on the theme. Trends Genet 2006;22:347-350.
    • (2006) Trends Genet , vol.22 , pp. 347-350
    • Petronis, A.1
  • 140
    • 0038155088 scopus 로고    scopus 로고
    • Opposite regulation by typical and atypical anti-psychotics of ERK1/2. CREB and Elk-1 phosphorylation in mouse dorsal striatum
    • Pozzi L, Hakansson K, Usiello A, Borgkvist A, Lindskog M, Grecngard P, et al. Opposite regulation by typical and atypical anti-psychotics of ERK1/2. CREB and Elk-1 phosphorylation in mouse dorsal striatum. J Neurochem 2003;86451-459.
    • (2003) J Neurochem , pp. 86451-86459
    • Pozzi, L.1    Hakansson, K.2    Usiello, A.3    Borgkvist, A.4    Lindskog, M.5    Grecngard, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.