메뉴 건너뛰기




Volumn , Issue , 2005, Pages 421-440

Selection of drug combinations in clinical practice: Current and future perspectives

Author keywords

[No Author keywords available]

Indexed keywords


EID: 35348907382     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511545023.025     Document Type: Chapter
Times cited : (6)

References (115)
  • 1
    • 0036214776 scopus 로고    scopus 로고
    • Is refractory epilepsy preventable?
    • Arroyo S, Brodie MJ, Avanzini G, et al. Is refractory epilepsy preventable? Epilepsia 2002; 43: 437–444.
    • (2002) Epilepsia , vol.43 , pp. 437-444
    • Arroyo, S.1    Brodie, M.J.2    Avanzini, G.3
  • 2
    • 8244234120 scopus 로고
    • Lamotrigine in patients with childhood onset intractable epilepsy
    • Arzimanoglou A, Gerardin V, Moszkowski J, et al. Lamotrigine in patients with childhood onset intractable epilepsy. Epilepsia 1993; 34(Suppl. 6): 113.
    • (1993) Epilepsia , vol.34 , pp. 113
    • Arzimanoglou, A.1    Gerardin, V.2    Moszkowski, J.3
  • 3
    • 0032444401 scopus 로고    scopus 로고
    • Therapeutic strategies against epilepsy in mediterranean countries: A report from an international collaborative surgery
    • Baldy-Moulinier M, Civanis A, D’Urso S, et al. Therapeutic strategies against epilepsy in Mediterranean countries: a report from an international collaborative surgery. Seizure 1998; 7: 513–520.
    • (1998) Seizure , vol.7 , pp. 513-520
    • Baldy-Moulinier, M.1    Civanis, A.2    D’Urso, S.3
  • 4
    • 0036045221 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of lamotrigine in patients suffering from resistant partial seizures
    • Benetello P, Furlanut M, Baraldo M, et al. Therapeutic drug monitoring of lamotrigine in patients suffering from resistant partial seizures. Eur Neurol 2002; 48: 200–203.
    • (2002) Eur Neurol , vol.48 , pp. 200-203
    • Benetello, P.1    Furlanut, M.2    Baraldo, M.3
  • 5
    • 0346798300 scopus 로고
    • Therapeutic interaction of lamotrigine with valproate and suximides
    • Besag FMC, Panayiotopoulos C, Chivers F, et al. Therapeutic interaction of lamotrigine with valproate and suximides. Epilepsia 1995; 36(Suppl. 3): 116.
    • (1995) Epilepsia , vol.36 , pp. 116
    • Besag, F.1    Panayiotopoulos, C.2    Chivers, F.3
  • 6
    • 0031883784 scopus 로고    scopus 로고
    • Carbamazepine toxicity with lamotrigine: Pharmacokinetic or pharmacodynamic interactions?
    • Besag FMC, Berry DJ, Pool F, et al. Carbamazepine toxicity with lamotrigine: pharmacokinetic or pharmacodynamic interactions? Epilepsia 1998; 39: 183–187.
    • (1998) Epilepsia , vol.39 , pp. 183-187
    • Besag, F.1    Berry, D.J.2    Pool, F.3
  • 7
    • 0034776082 scopus 로고    scopus 로고
    • Efficacy of lamotrigine add-on therapy in severe partial epilepsy in adults with drop seizures and secondary bilateral synchrony on eeg
    • Bisulli F, Baruzzi A, Rosati A, et al. Efficacy of lamotrigine add-on therapy in severe partial epilepsy in adults with drop seizures and secondary bilateral synchrony on EEG. Epileptic Disord 2001; 3: 151–156.
    • (2001) Epileptic Disord , vol.3 , pp. 151-156
    • Bisulli, F.1    Baruzzi, A.2    Rosati, A.3
  • 8
    • 0000231206 scopus 로고    scopus 로고
    • Adjunctive tiagabine compared with phenytoin and carbamazepine in multicenter, double-blind trial of complex partial seizures
    • Biton V, Vasquez B, Sachedo RC, et al. Adjunctive tiagabine compared with phenytoin and carbamazepine in multicenter, double-blind trial of complex partial seizures. Epilepsia 1998; 39(Suppl. 6): 125–126.
    • (1998) Epilepsia , vol.39 , pp. 125-126
    • Biton, V.1    Vasquez, B.2    Sachedo, R.C.3
  • 9
    • 0022907940 scopus 로고
    • Antiepileptic drug combinations and experimental background: The case of phenobarbital and phenytoin
    • Bourgeois BFD. Antiepileptic drug combinations and experimental background: the case of phenobarbital and phenytoin. Naunyn Schmiedebergs Arch Pharmacol 1986; 333: 406–411.
    • (1986) Naunyn Schmiedebergs Arch Pharmacol , vol.333 , pp. 406-411
    • Bourgeois, B.1
  • 10
    • 0024239758 scopus 로고
    • Combination of valproate and ethosuximide: Antiepileptic and neurotoxic interactions
    • Bourgeois BFD. Combination of valproate and ethosuximide: Antiepileptic and neurotoxic interactions. J Pharmacol Ther 1988; 247: 1128–1132.
    • (1988) J Pharmacol Ther , vol.247 , pp. 1128-1132
    • Bourgeois, B.1
  • 11
    • 0030975686 scopus 로고    scopus 로고
    • 105 study group. Lamotrigine substitution study: Evidence for synergism with sodium valproate
    • Brodie MJ, Yuen AC, 105 Study Group. Lamotrigine substitution study: evidence for synergism with sodium valproate. Epilepsy Res 1997; 26: 423–432.
    • (1997) Epilepsy Res , vol.26 , pp. 423-432
    • Brodie, M.J.1    Yuen, A.C.2
  • 12
    • 0032891687 scopus 로고    scopus 로고
    • Double blind substitution of vigabatrin and valproate in carbamazepine-resistant partial epilepsy
    • Brodie MJ, Mumford JP for the 012 Study Group. Double blind substitution of vigabatrin and valproate in carbamazepine-resistant partial epilepsy. Epilepsy Res 1999; 40: 199–205.
    • (1999) Epilepsy Res , vol.40 , pp. 199-205
    • Brodie, M.J.1    Mumford, J.P.2
  • 13
    • 0029927328 scopus 로고    scopus 로고
    • Antiepileptic drug therapy: When is epilepsy truly intractable?
    • Camfield PR, Camfield CS. Antiepileptic drug therapy: when is epilepsy truly intractable? Epilepsia 1996; 37(Suppl. 1): 60–65.
    • (1996) Epilepsia , vol.37 , pp. 60-65
    • Camfield, P.R.1    Camfield, C.S.2
  • 16
    • 0036047026 scopus 로고    scopus 로고
    • Zonisamide add-on for drug-resistant partial epilepsy
    • Issue, 2. Oxford: Update Software
    • Chadwick DW, Marson AG. Zonisamide add-on for drug-resistant partial epilepsy Cochrane Rev. The Cochrane Library 2003; Issue, 2. Oxford: Update Software.
    • (2003) Cochrane Rev. the Cochrane Library
    • Chadwick, D.W.1    Marson, A.G.2
  • 17
    • 0035231827 scopus 로고    scopus 로고
    • Calcium antagonists as an add-on therapy for drugresistant epilepsy
    • ; Issue 4, Oxford: Update Software
    • Chaisewikul R, Baillie N, Marson AG. Calcium antagonists as an add-on therapy for drugresistant epilepsy. Cochrane Rev. Cochrane Library 2001a; Issue 4, Oxford: Update Software.
    • (2001) Cochrane Rev. Cochrane Library
    • Chaisewikul, R.1    Baillie, N.2    Marson, A.G.3
  • 18
    • 0035227979 scopus 로고    scopus 로고
    • Levetiracetam add-on for drug-resistant localization related (Partial) epilepsy
    • CD001901
    • Chaisewikul R, Privitera MD, Hutton JL, et al. Levetiracetam add-on for drug-resistant localization related (partial) epilepsy. Cochrane Database Syst Rev 2001b; CD001901.
    • (2001) Cochrane Database Syst Rev
    • Chaisewikul, R.1    Privitera, M.D.2    Hutton, J.L.3
  • 19
    • 85066652105 scopus 로고
    • Studies on the clinical efficacy of marketed antiepileptic drugs
    • Coatsworth JJ. Studies on the clinical efficacy of marketed antiepileptic drugs. NIH PHS USDHEW Bethesda Md 1971; 5: 393.
    • (1971) NIH PHS USDHEW Bethesda Md , vol.5 , pp. 393
    • Coatsworth, J.J.1
  • 20
    • 0002676268 scopus 로고    scopus 로고
    • Experimental background for synergistic and additive effects of antiepileptic drugs
    • Czuczwar SJ. Experimental background for synergistic and additive effects of antiepileptic drugs. Epileptologia 1998; 6(Suppl. 2): 21–29.
    • (1998) Epileptologia , vol.6 , pp. 21-29
    • Czuczwar, S.J.1
  • 21
    • 0036850041 scopus 로고    scopus 로고
    • Polytherapy in epilepsy: The experimental evidence
    • Czuczwar SJ, Borowicz KK. Polytherapy in epilepsy: the experimental evidence. Epilepsy Res 2002; 52: 15–23.
    • (2002) Epilepsy Res , vol.52 , pp. 15-23
    • Czuczwar, S.J.1    Borowicz, K.K.2
  • 22
    • 0026437477 scopus 로고
    • Influence of flunarizine, nicardipine and nimodipine on the anticonvulsant activity of different antiepileptic drugs in mice
    • Czuczwar SJ, Gasior M, Janusz W, et al. Influence of flunarizine, nicardipine and nimodipine on the anticonvulsant activity of different antiepileptic drugs in mice. Neuropharmacology 1992; 31: 1179–1183.
    • (1992) Neuropharmacology , vol.31 , pp. 1179-1183
    • Czuczwar, S.J.1    Gasior, M.2    Janusz, W.3
  • 23
    • 0001589132 scopus 로고
    • Carbamazepine/valproate therapy in 100 patients with partial seizures failing carbamazepine monotherapy: Long-term follow-up
    • Dean JC, Penry JK. Carbamazepine/valproate therapy in 100 patients with partial seizures failing carbamazepine monotherapy: long-term follow-up. Epilepsia 1988; 29: 687.
    • (1988) Epilepsia , vol.29 , pp. 687
    • Dean, J.C.1    Penry, J.K.2
  • 24
    • 0033761218 scopus 로고    scopus 로고
    • Selection of antiepileptic drug polytherapy based on mechanism of action: The evidence reviewed
    • Deckers CLP, Czuczwar SJ, Hekster YA, et al. Selection of antiepileptic drug polytherapy based on mechanism of action: the evidence reviewed. Epilepsia 2000; 41: 1364–1374.
    • (2000) Epilepsia , vol.41 , pp. 1364-1374
    • Deckers, C.1    Czuczwar, S.J.2    Hekster, Y.A.3
  • 25
    • 0035207331 scopus 로고    scopus 로고
    • Monotherapy versus polytherapy for epilepsy: A multicenter double-blind randomised study
    • Deckers CLP, Hekster YA, Keyser A, et al. Monotherapy versus polytherapy for epilepsy: A multicenter double-blind randomised study. Epilepsia 2001; 42: 1387–1394.
    • (2001) Epilepsia , vol.42 , pp. 1387-1394
    • Deckers, C.1    Hekster, Y.A.2    Keyser, A.3
  • 26
    • 12244288290 scopus 로고    scopus 로고
    • Current limitations of antiepileptic drug therapy; a conference review
    • Deckers CLP, Genton P, Sills GJ, et al. Current limitations of antiepileptic drug therapy; a conference review. Epilepsy Res 2003; 53: 1–17.
    • (2003) Epilepsy Res , vol.53 , pp. 1-17
    • Deckers, C.1    Genton, P.2    Sills, G.J.3
  • 27
    • 84889223558 scopus 로고    scopus 로고
    • Lamotrigine and topiramate combination therapy: Experience from postmarking surveillance
    • Delanty N, French JA, Williams SF. Lamotrigine and topiramate combination therapy: experience from postmarking surveillance. Epilepsia 1998; 39(Suppl. 6): 131.
    • (1998) Epilepsia , vol.39 , pp. 131
    • Delanty, N.1    French, J.A.2    Williams, S.F.3
  • 28
    • 0020662030 scopus 로고
    • Principles in designing clinical trials for antiepileptic drugs
    • Delgado-Escueta AV, Mattson RH, Smith DB, et al. Principles in designing clinical trials for antiepileptic drugs. Neurology 1983; 33(Suppl. 1): 8–13.
    • (1983) Neurology , vol.33 , pp. 8-13
    • Delgado-Escueta, A.V.1    Mattson, R.H.2    Smith, D.B.3
  • 29
    • 0032736593 scopus 로고    scopus 로고
    • Lamotrigine in the therapy of resistant epilepsy
    • De Romanis F, Sopranzi N. Lamotrigine in the therapy of resistant epilepsy. Clin Therapeutica 1999; 150: 279–282.
    • (1999) Clin Therapeutica , vol.150 , pp. 279-282
    • De Romanis, F.1    Sopranzi, N.2
  • 30
    • 0019234033 scopus 로고
    • Didepil for the treatment of epilepsy
    • J. Majkowski, ed. Monogr Neural Sci. Basel: S. Karger
    • Doychinov D. Didepil for the treatment of epilepsy. In Epilepsy: A Clinical and Experimental Research. J. Majkowski, ed. Monogr Neural Sci. Basel: S. Karger, 1980: 112–118.
    • (1980) In Epilepsy: A Clinical and Experimental Research , pp. 112-118
    • Doychinov, D.1
  • 31
    • 0002318521 scopus 로고    scopus 로고
    • Principles of treatment of patients with chronic active epilepsy
    • S. Shorvon, F. Dreifuss, D. Fish, D. Thomas, eds. Oxford: Blackwell Science
    • Duncan JS. Principles of treatment of patients with chronic active epilepsy. In The Treatment of Epilepsies. S. Shorvon, F. Dreifuss, D. Fish, D. Thomas, eds. Oxford: Blackwell Science, 1996: 177–190.
    • (1996) The Treatment of Epilepsies , pp. 177-190
    • Duncan, J.S.1
  • 32
    • 0033045047 scopus 로고    scopus 로고
    • Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: Influence of experimental and environmental factors
    • Ebert U, Rundfeldt C, Lehmann H, et al. Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: influence of experimental and environmental factors. Epilepsy Res 1999, 33: 199–215.
    • (1999) Epilepsy Res , vol.33 , pp. 199-215
    • Ebert, U.1    Rundfeldt, C.2    Lehmann, H.3
  • 33
    • 0032821534 scopus 로고    scopus 로고
    • Options after the first antiepileptic drug has failed
    • Elger CE, Fernandez, G. Options after the first antiepileptic drug has failed. Epilepsia 1999; 40(Suppl. 6): 9–12.
    • (1999) Epilepsia , vol.40 , pp. 9-12
    • Elger, C.E.1    Fernandez, G.2
  • 34
    • 0037117058 scopus 로고    scopus 로고
    • Is drug resistant partial epilepsy progressive?
    • Elices E, Arroyo S. Is drug resistant partial epilepsy progressive? Rev Neurol 2002; 34: 505–510.
    • (2002) Rev Neurol , vol.34 , pp. 505-510
    • Elices, E.1    Arroyo, S.2
  • 36
    • 2642598051 scopus 로고    scopus 로고
    • The efficacy of lamotrigine in children and adolescent with refractory generalized epilepsy: A randomized, double-blind, crossover study
    • Eriksson AS, Nergardh A, Hoppu K. The efficacy of lamotrigine in children and adolescent with refractory generalized epilepsy: a randomized, double-blind, crossover study. Epilepsia 1998; 39: 495–501.
    • (1998) Epilepsia , vol.39 , pp. 495-501
    • Eriksson, A.S.1    Nergardh, A.2    Hoppu, K.3
  • 37
    • 0021710051 scopus 로고
    • Intermittent clobazam for catamenial epilepsy: Tolerance avoided
    • Feely M, Gibson J. Intermittent clobazam for catamenial epilepsy: tolerance avoided. J Neurol Neurosurg Psychiatr 1984; 47: 1279–1282.
    • (1984) J Neurol Neurosurg Psychiatr , vol.47 , pp. 1279-1282
    • Feely, M.1    Gibson, J.2
  • 38
    • 85066695173 scopus 로고    scopus 로고
    • Therapeutic interactions of lamotrigine and sodium valproate in intractable myoclonic epilepsy
    • Ferrie CD, Panayiotopoulos CP. Therapeutic interactions of lamotrigine and sodium valproate in intractable myoclonic epilepsy. Seizure 1999; 3: 1375–1376.
    • (1999) Seizure , vol.3 , pp. 1375-1376
    • Ferrie, C.D.1    Panayiotopoulos, C.P.2
  • 39
    • 0029042569 scopus 로고
    • Rational polypharmacy
    • Ferrendelli JA. Rational polypharmacy. Epilepsia 1995; 36(Suppl. 2): 115–118.
    • (1995) Epilepsia , vol.36 , pp. 115-118
    • Ferrendelli, J.A.1
  • 40
    • 0000929415 scopus 로고    scopus 로고
    • Do lamotrigine and valproic acid have an additive anticonvulsant effect
    • Frey M, Kanner AM. Do lamotrigine and valproic acid have an additive anticonvulsant effect. Epilepsia 1999; 40(Suppl. 7): 144.
    • (1999) Epilepsia , vol.40 , pp. 144
    • Frey, M.1    Kanner, A.M.2
  • 41
    • 0007883462 scopus 로고    scopus 로고
    • Synergistic and additive effects of antiepileptic drugs in epileptic patients
    • Fröscher W. Synergistic and additive effects of antiepileptic drugs in epileptic patients. Epileptologia 1998; 6(Suppl. 2): 31–42.
    • (1998) Epileptologia , vol.6 , pp. 31-42
    • Fröscher, W.1
  • 42
    • 37349127376 scopus 로고    scopus 로고
    • Clinical experience with synergistic and additive effects of antiepileptic drugs in epileptic patients – new developments
    • Fröscher W. Clinical experience with synergistic and additive effects of antiepileptic drugs in epileptic patients – new developments. Epileptologia 2000; 8: 221–227.
    • (2000) Epileptologia , vol.8 , pp. 221-227
    • Fröscher, W.1
  • 43
    • 0021244676 scopus 로고
    • Kombinationsbehandlung mit carbamazepin und valproinsäure bei problemfällen einer epilepsie-ambulanz
    • Fröscher W, Stodl K-D, Hoffmann F. Kombinationsbehandlung mit Carbamazepin und Valproinsäure bei Problemfällen einer Epilepsie-Ambulanz. Arzneim Forsch 1984; 34: 910–914.
    • (1984) Arzneim Forsch , vol.34 , pp. 910-914
    • Fröscher, W.1    Stodl, K.-D.2    Hoffmann, F.3
  • 44
    • 0026697901 scopus 로고
    • Vigabatrin bei pharmakoresistenten epilepsien
    • Fröscher W, Rauber A, Rothmeier J, et al. Vigabatrin bei pharmakoresistenten Epilepsien. Akt Neurol 1992; 19: 48–49.
    • (1992) Akt Neurol , vol.19 , pp. 48-49
    • Fröscher, W.1    Rauber, A.2    Rothmeier, J.3
  • 45
    • 0022642461 scopus 로고
    • A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis
    • Gorman WP, Cooper R, Pocock P, et al. A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis. J Neurol Neurosurg Psychiatr 1986; 49: 64–68.
    • (1986) J Neurol Neurosurg Psychiatr , vol.49 , pp. 64-68
    • Gorman, W.P.1    Cooper, R.2    Pocock, P.3
  • 46
    • 0036785082 scopus 로고    scopus 로고
    • Epaj-119 study group. Low-dose topiramate in adults with treatment-resistant partial-onset seizures
    • Guberman A, Neto W, Gassmann-Mayer C, EPAJ-119 Study Group. Low-dose topiramate in adults with treatment-resistant partial-onset seizures. Acta Neurol Scand 2002; 106: 183–189.
    • (2002) Acta Neurol Scand , vol.106 , pp. 183-189
    • Guberman, A.1    Neto, W.2    Gassmann-Mayer, C.3
  • 47
    • 0002704158 scopus 로고
    • Carbamazepine vs diphenylhydatoin vs their combination in adult epilepsy
    • Hakkarainen H. Carbamazepine vs diphenylhydatoin vs their combination in adult epilepsy. Neurology 1980; 30: 354.
    • (1980) Neurology , vol.30 , pp. 354
    • Hakkarainen, H.1
  • 49
    • 0033974461 scopus 로고    scopus 로고
    • Effect of vigabatrin addition on carbamazepine blood serum levels in patients with epilepsy
    • Jêdrzejczak J, Dlawichowska E, Owczarek K, et al. Effect of vigabatrin addition on carbamazepine blood serum levels in patients with epilepsy. Epilepsy Res 2000; 39: 115–120.
    • (2000) Epilepsy Res , vol.39 , pp. 115-120
    • Jêdrzejczak, J.1    Dlawichowska, E.2    Owczarek, K.3
  • 50
    • 85066649847 scopus 로고    scopus 로고
    • The dynamics of natural, undiagnosed epilepsy of many years’ duration – diagnostic difficulties. Three case studies
    • Jêdrzejczak J, Leñska-Mieciek M, Tomik BJ. The dynamics of natural, undiagnosed epilepsy of many years’ duration – diagnostic difficulties. Three case studies. Epileptologia 2002; 10: 163–174.
    • (2002) Epileptologia , vol.10 , pp. 163-174
    • Jêdrzejczak, J.1    Leñska-Mieciek, M.2    Tomik, B.J.3
  • 51
    • 0023000675 scopus 로고
    • Carbamazepine-danazol drug interaction: Its metabolism examined by a stable isotope technique
    • Krämer G, Theisohn M, von Unruh GE, et al. Carbamazepine-danazol drug interaction: its metabolism examined by a stable isotope technique. Ther Drug Monit 1986; 8: 387–392.
    • (1986) Ther Drug Monit , vol.8 , pp. 387-392
    • Krämer, G.1    Theisohn, M.2    Von Unruh, G.E.3
  • 52
    • 0000349429 scopus 로고    scopus 로고
    • Efficacy of combination topiramate and lamotrigine in refractory epilepsy in children
    • Kugler St. L, Sachedo RC, Wenger EC, et al. Efficacy of combination topiramate and lamotrigine in refractory epilepsy in children. Epilepsia 1997; 38(Suppl. 8): 192–193.
    • (1997) Epilepsia , vol.38 , pp. 192-193
    • Kugler, L.1    Sachedo, R.C.2    Wenger, E.C.3
  • 53
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan P, Brodie MJ. Early identification of refractory epilepsy. Engl J Med 2000; 342: 314–319.
    • (2000) Engl J Med , vol.342 , pp. 314-319
    • Kwan, P.1    Brodie, M.J.2
  • 54
    • 0028304171 scopus 로고
    • Synergism with gaba-ergic drugs in refractory epilepsy (Letter)
    • Leach JP, Brodie MJ. Synergism with GABA-ergic drugs in refractory epilepsy (letter). Lancet 1994; 343: 1650.
    • (1994) Lancet , vol.343 , pp. 1650
    • Leach, J.P.1    Brodie, M.J.2
  • 55
    • 0027383365 scopus 로고
    • Antiepileptic medication interactions
    • Leppik LE, Wolff DL. Antiepileptic medication interactions. Neurologic Clinics 1993; 11: 905–921.
    • (1993) Neurologic Clinics , vol.11 , pp. 905-921
    • Leppik, L.E.1    Wolff, D.L.2
  • 56
    • 0036109602 scopus 로고    scopus 로고
    • Animal models of drug-resistant epilepsy
    • Löscher W. Animal models of drug-resistant epilepsy. Novartis Found Symp 2002; 243: 149–159.
    • (2002) Novartis Found Symp , vol.243 , pp. 149-159
    • Löscher, W.1
  • 57
    • 85066650155 scopus 로고    scopus 로고
    • Basic mechanisms of seizure propagation: Targets for rational drug design and rational polypharmacy
    • Löscher W, Ebert U. Basic mechanisms of seizure propagation: targets for rational drug design and rational polypharmacy. Epilepsy Res Suppl 1996; 11: 3–7.
    • (1996) Epilepsy Res Suppl , vol.11 , pp. 3-7
    • Löscher, W.1    Ebert, U.2
  • 58
    • 0036347770 scopus 로고    scopus 로고
    • Critical re-evaluation of previous preclinical strategies for the discovery and the development of new antiepileptic drugs
    • Löscher W, Leppik IE. Critical re-evaluation of previous preclinical strategies for the discovery and the development of new antiepileptic drugs. Epilepsy Res 2002; 50: 17–20.
    • (2002) Epilepsy Res , vol.50 , pp. 17-20
    • Löscher, W.1    Leppik, I.E.2
  • 59
    • 0642308238 scopus 로고    scopus 로고
    • Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice
    • Luszczki JJ, Swiader M, Parada-Turska J, et al. Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice. Neuropsychopharmacology 2003; 28: 1817–1830.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1817-1830
    • Luszczki, J.J.1    Swiader, M.2    Parada-Turska, J.3
  • 60
    • 0025046356 scopus 로고
    • National institutes of health consensus conference. Surgery for epilepsy
    • Lu¨ders HO
    • Lu¨ders HO. National Institutes of Health Consensus Conference. Surgery for epilepsy. J Am Med Assoc 1990; 264: 729–733.
    • (1990) J am Med Assoc , vol.264 , pp. 729-733
  • 62
    • 0021051630 scopus 로고
    • Drug effects on after discharge and seizure threshold in lissencephalic ferrets: An epilepsy model for drug evaluation
    • Majkowski J. Drug effects on after discharge and seizure threshold in lissencephalic ferrets: an epilepsy model for drug evaluation. Epilepsia 1983; 24: 678–685.
    • (1983) Epilepsia , vol.24 , pp. 678-685
    • Majkowski, J.1
  • 63
    • 85066671642 scopus 로고    scopus 로고
    • Drug resistant epilepsy and rational polytherapy in the era of new antiepileptic drug
    • Majkowski J. Drug resistant epilepsy and rational polytherapy in the era of new antiepileptic drug. Epileptologia 1996; 4: 281–293.
    • (1996) Epileptologia , vol.4 , pp. 281-293
    • Majkowski, J.1
  • 64
    • 0011892239 scopus 로고    scopus 로고
    • Natural course of epileptogenesis: From partial simple to partial complex seizures. a case report
    • Majkowski J. Natural course of epileptogenesis: from partial simple to partial complex seizures. A case report. Epileptologia 1998; 6: 99–112.
    • (1998) Epileptologia , vol.6 , pp. 99-112
    • Majkowski, J.1
  • 65
    • 0033256257 scopus 로고    scopus 로고
    • Kindling: Clinical relevance for epileptogenicity in humans. in
    • H. Stefan, F. Andermann, P. Chauvel, S. Shorvon, eds., Philadelphia: Lippincott Williams & Wilkins,;
    • Majkowski J. Kindling: clinical relevance for epileptogenicity in humans. In Advances in Neurology. H. Stefan, F. Andermann, P. Chauvel, S. Shorvon, eds., Philadelphia: Lippincott Williams & Wilkins, 1999; 81, 105–113.
    • (1999) Advances in Neurology , vol.81 , pp. 105-113
    • Majkowski, J.1
  • 66
    • 0011813016 scopus 로고    scopus 로고
    • The natural progression of epileptogenesis: From partial simple visual seizure to complex and secondary generalised seizures. a case study
    • Majkowski J. The natural progression of epileptogenesis: from partial simple visual seizure to complex and secondary generalised seizures. A case study. Epileptologia 2000; 7: 47–58.
    • (2000) Epileptologia , vol.7 , pp. 47-58
    • Majkowski, J.1
  • 67
    • 0021245612 scopus 로고
    • Eeg and seizure threshold in normal and lissencephalic ferrets
    • Majkowski J, Lee MH, Kozlowski PB, et al. EEG and seizure threshold in normal and lissencephalic ferrets. Brain Res 1984; 307: 29–38.
    • (1984) Brain Res , vol.307 , pp. 29-38
    • Majkowski, J.1    Lee, M.H.2    Kozlowski, P.B.3
  • 68
    • 0022993802 scopus 로고
    • Differences in antiepileptic drug efficacy in hippocampal kindled normal and microcephalic rats
    • Majkowski J, Danneberg P, Knappen F. Differences in antiepileptic drug efficacy in hippocampal kindled normal and microcephalic rats. Brain Res 1986; 386: 325–331.
    • (1986) Brain Res , vol.386 , pp. 325-331
    • Majkowski, J.1    Danneberg, P.2    Knappen, F.3
  • 69
    • 85066661988 scopus 로고
    • Prophylaxis and control of febrile convulsion (Fc) by rectal administration of diazepam. prospective study. preliminary report
    • Majkowski J, Sidor K, Wendorff J, et al. Prophylaxis and control of febrile convulsion (FC) by rectal administration of diazepam. Prospective study. Preliminary Report. Epileptologia 1995; 3: 111–120.
    • (1995) Epileptologia , vol.3 , pp. 111-120
    • Majkowski, J.1    Sidor, K.2    Wendorff, J.3
  • 70
    • 85066703563 scopus 로고    scopus 로고
    • Pharmacological treatment of epilepsy in poland 2000–2001. Multicenter prospective study of 6195 patients
    • : In press
    • Majkowski J, Kacinski M, Jedrzejazak J, et al. Pharmacological treatment of epilepsy in Poland 2000–2001. Multicenter Prospective Study of 6195 Patients. Epideplogia 2005; 13: In press
    • (2005) Epideplogia , vol.13
    • Majkowski, J.1    Kacinski, M.2    Jedrzejazak, J.3
  • 71
    • 0037404826 scopus 로고    scopus 로고
    • Vascular and parenchymal mechanisms in multiple drug resistance: A lesson from human epilepsy
    • Marroni M, Marchi N, Cucullo L, et al. Vascular and parenchymal mechanisms in multiple drug resistance: a lesson from human epilepsy. Curr Drug Targets 2003; 4: 297–304.
    • (2003) Curr Drug Targets , vol.4 , pp. 297-304
    • Marroni, M.1    Marchi, N.2    Cucullo, L.3
  • 72
    • 0034892505 scopus 로고    scopus 로고
    • Levetiracetam, oxcarbazepine and zonisamide for drug resistant localisation related epilepsy: A systemic review
    • Marson AG, Hutton JL, Leach JP, et al. Levetiracetam, oxcarbazepine and zonisamide for drug resistant localisation related epilepsy: a systemic review. Epilepsy Res 2001; 46: 259–270.
    • (2001) Epilepsy Res , vol.46 , pp. 259-270
    • Marson, A.G.1    Hutton, J.L.2    Leach, J.P.3
  • 73
    • 0019469190 scopus 로고
    • Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals
    • Masuda Y, Utsui Y, Shiraishi Y, et al. Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals. J Pharmacol Exp Ther, 1981; 217: 805–811.
    • (1981) J Pharmacol Exp Ther , vol.217 , pp. 805-811
    • Masuda, Y.1    Utsui, Y.2    Shiraishi, Y.3
  • 74
    • 0026479707 scopus 로고
    • Drug treatment of partial epilepsies
    • Mattson RH. Drug treatment of partial epilepsies. Adv Neurol 1992; 57: 643–650.
    • (1992) Adv Neurol , vol.57 , pp. 643-650
    • Mattson, R.H.1
  • 75
    • 0023780143 scopus 로고
    • Crossover from polytherapy to monotherapy in primary generalised epilepsy
    • Mattson RH, Cramer JA. Crossover from polytherapy to monotherapy in primary generalised epilepsy. Amer J Med 1988; 84(Suppl. 1A): 23–38.
    • (1988) Amer J Med , vol.84 , pp. 23-38
    • Mattson, R.H.1    Cramer, J.A.2
  • 76
    • 0344760630 scopus 로고
    • Medroxyprogesterone treatment of women with uncontrolled seizures
    • Mattson RH, Klein PE, Caldwell BV, et al. Medroxyprogesterone treatment of women with uncontrolled seizures. Epilepsia 1982; 23: 436–437.
    • (1982) Epilepsia , vol.23 , pp. 436-437
    • Mattson, R.H.1    Klein, P.E.2    Caldwell, B.V.3
  • 77
    • 0020659612 scopus 로고
    • A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults
    • Mattson RH, Cramer JA, Delgado-Escueta AV, et al. A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults. Neurology 1983; 33(Suppl. 1): 14–25.
    • (1983) Neurology , vol.33 , pp. 14-25
    • Mattson, R.H.1    Cramer, J.A.2    Delgado-Escueta, A.V.3
  • 78
    • 84989525536 scopus 로고
    • Vigabatrin as first add-on treatment in carbamazepine-resistant epilepsy patients
    • Muri L, Judice A. Vigabatrin as first add-on treatment in carbamazepine-resistant epilepsy patients. Acta Neurol Scand 1995; 62(Suppl. 1): 40–42.
    • (1995) Acta Neurol Scand , vol.62 , pp. 40-42
    • Muri, L.1    Judice, A.2
  • 79
    • 0023797364 scopus 로고
    • Rational treatment of refractory epilepsy in childhood
    • Ohtsuka Y, Ogino T, Amano R, et al. Rational treatment of refractory epilepsy in childhood. Jpn J Psychiatr Neurol 1988; 42: 443–447.
    • (1988) Jpn J Psychiatr Neurol , vol.42 , pp. 443-447
    • Ohtsuka, Y.1    Ogino, T.2    Amano, R.3
  • 80
    • 0027477375 scopus 로고
    • Interaction of lamotrigine with sodium valproate (Letter)
    • Panayiotopoulos CP, Ferrie CD, Knott C, et al. Interaction of lamotrigine with sodium valproate (letter). Lancet 1993; 341: 445.
    • (1993) Lancet , vol.341 , pp. 445
    • Panayiotopoulos, C.P.1    Ferrie, C.D.2    Knott, C.3
  • 81
    • 0038196961 scopus 로고    scopus 로고
    • Clinically important drug interactions in epilepsy: General features and interactions between antiepileptic drugs
    • Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs. Lancet Neurol 2003; 2: 347–356.
    • (2003) Lancet Neurol , vol.2 , pp. 347-356
    • Patsalos, P.N.1    Perucca, E.2
  • 82
    • 0036220551 scopus 로고    scopus 로고
    • The importance of drug interactions in epilepsy therapy
    • Patsalos PN, Fröscher W, Pisani F, et al. The importance of drug interactions in epilepsy therapy. Epilepsia 2002; 43: 365–385.
    • (2002) Epilepsia , vol.43 , pp. 365-385
    • Patsalos, P.N.1    Fröscher, W.2    Pisani, F.3
  • 84
    • 0017079613 scopus 로고
    • Interlaboratory variability in determination of plasma antiepileptic drug concentrations
    • Pippenger CE, Penry JK, White BG, et al. Interlaboratory variability in determination of plasma antiepileptic drug concentrations. Arch Neurol 1976; 33: 351–355.
    • (1976) Arch Neurol , vol.33 , pp. 351-355
    • Pippenger, C.E.1    Penry, J.K.2    White, B.G.3
  • 85
    • 0027215110 scopus 로고
    • Interaction of lamotrigine with sodium valproate
    • Pisani F, Di Perri R, Perucca E, et al. Interaction of lamotrigine with sodium valproate. Lancet 1993; 341: 1224.
    • (1993) Lancet , vol.341 , pp. 1224
    • Pisani, F.1    Di Perri, R.2    Perucca, E.3
  • 86
    • 0032799794 scopus 로고    scopus 로고
    • The efficacy of valproate–lamotrigine comedication in refractory complex partial seizures: Evidence for pharmacodynamic interactions
    • Pisani F, Oteri G, Russo MF, et al. The efficacy of valproate–lamotrigine comedication in refractory complex partial seizures: evidence for pharmacodynamic interactions. Epilepsia 1999a; 40: 1141–1146.
    • (1999) Epilepsia , vol.40 , pp. 1141-1146
    • Pisani, F.1    Oteri, G.2    Russo, M.F.3
  • 87
    • 0343719299 scopus 로고    scopus 로고
    • Complete seizure control following gabapentin–lamotrigine comedication
    • Pisani F, Oteri G, Antonino F, et al. Complete seizure control following gabapentin–lamotrigine comedication. Epilepsia 1999b; 40(Suppl. 2): 253–254.
    • (1999) Epilepsia , vol.40 , pp. 253-254
    • Pisani, F.1    Oteri, G.2    Antonino, F.3
  • 88
    • 0347364703 scopus 로고    scopus 로고
    • Brain access and anticonvulsant of carbamazepine, lamotrigine, and felbamate in arcc2/mrp2 – deficient tr-rats
    • Potschka H, Fedrowitz M, Löscher W. Brain access and anticonvulsant of carbamazepine, lamotrigine, and felbamate in ARCC2/MRP2 – deficient TR-rats. Epilepsia 2003a; 44: 1479–1486.
    • (2003) Epilepsia , vol.44 , pp. 1479-1486
    • Potschka, H.1    Fedrowitz, M.2    Löscher, W.3
  • 89
    • 0037665280 scopus 로고    scopus 로고
    • Multidrug resistance protein mrp2 contributes to blood–brain barrier function and restricts antiepileptic drug activity
    • Potschka H, Fedrowitz M, Löscher W. Multidrug resistance protein MRP2 contributes to blood–brain barrier function and restricts antiepileptic drug activity. J Pharmacol Exp Ther 2003b; 306: 124–131.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 124-131
    • Potschka, H.1    Fedrowitz, M.2    Löscher, W.3
  • 90
    • 0036153799 scopus 로고    scopus 로고
    • Distribution of glutamate transporters in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy
    • Proper EA, Hoogland G, Kappen SM, et al. Distribution of glutamate transporters in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy. Brain 2002; 125: 32–43.
    • (2002) Brain , vol.125 , pp. 32-43
    • Proper, E.A.1    Hoogland, G.2    Kappen, S.M.3
  • 92
    • 0345382778 scopus 로고    scopus 로고
    • A novel mechanism underlying drug resistance in chronic epilepsy
    • Remy S, Gabriel S, Urban BW, et al. A novel mechanism underlying drug resistance in chronic epilepsy. Ann. Neurol 2003; 53: 469–479.
    • (2003) Ann. Neurol , vol.53 , pp. 469-479
    • Remy, S.1    Gabriel, S.2    Urban, B.W.3
  • 93
    • 0019349776 scopus 로고
    • Monotherapy or polytherapy for epilepsy?
    • Reynolds EH, Shorvon SD. Monotherapy or polytherapy for epilepsy? Epilepsia 1981; 22: 1–10.
    • (1981) Epilepsia , vol.22 , pp. 1-10
    • Reynolds, E.H.1    Shorvon, S.D.2
  • 94
    • 0036342427 scopus 로고    scopus 로고
    • Efficacy and tolerability of long term topiramate in drug resistant epilepsy in adults
    • Ribacoba Montero R, Salas Puig X. Efficacy and tolerability of long term topiramate in drug resistant epilepsy in adults. Rev Neurol 2002; 34: 101–105.
    • (2002) Rev Neurol , vol.34 , pp. 101-105
    • Ribacoba Montero, R.1    Salas Puig, X.2
  • 96
    • 0344889789 scopus 로고
    • Combined gamma-vinyl-gaba (Vigabatrin) and lamotrigine therapy in management of refractory epilepsy
    • Robinson MK, Black AB, Schapel GS, et al. Combined gamma-vinyl-GABA (vigabatrin) and lamotrigine therapy in management of refractory epilepsy. Epilepsia 1993; 34(Suppl. 2): 109.
    • (1993) Epilepsia , vol.34 , pp. 109
    • Robinson, M.K.1    Black, A.B.2    Schapel, G.S.3
  • 97
    • 0021071203 scopus 로고
    • Valproate–ethosuximide combination therapy for refractory absence seizures
    • Rowan AJ, Meijer JWA, de Beer-Pawlikowski N, et al. Valproate–ethosuximide combination therapy for refractory absence seizures. Arch Neurol 1983; 40: 797–802.
    • (1983) Arch Neurol , vol.40 , pp. 797-802
    • Rowan, A.J.1    Meijer, J.2    De Beer-Pawlikowski, N.3
  • 98
    • 0342618681 scopus 로고    scopus 로고
    • Influence of ethosuximide on valproic acid serum concentrations
    • Sälke-Kellermann RA, May T, Boenigk HE. Influence of ethosuximide on valproic acid serum concentrations. Epilepsy Res 1997; 26: 345–349.
    • (1997) Epilepsy Res , vol.26 , pp. 345-349
    • Sälke-Kellermann, R.A.1    May, T.2    Boenigk, H.E.3
  • 99
    • 0029867298 scopus 로고    scopus 로고
    • Combination vigabatrin and lamotrigine therapy for intractable epilepsy
    • Schapel GJ, Black AB, Lam EL, et al. Combination vigabatrin and lamotrigine therapy for intractable epilepsy. Seizure 1996; 5: 51–56.
    • (1996) Seizure , vol.5 , pp. 51-56
    • Schapel, G.J.1    Black, A.B.2    Lam, E.L.3
  • 100
    • 0020446242 scopus 로고
    • Two antiepileptic drugs for intractable epilepsy with complex partial seizures
    • Schmidt D. Two antiepileptic drugs for intractable epilepsy with complex partial seizures. J Neurol Neurosurg Psychiatr 1982; 45: 1119–1124.
    • (1982) J Neurol Neurosurg Psychiatr , vol.45 , pp. 1119-1124
    • Schmidt, D.1
  • 101
    • 0028815488 scopus 로고
    • Monotherapy versus polytherapy in epilepsy. A reappraisal
    • Schmidt D, Gram L. Monotherapy versus polytherapy in epilepsy. A reappraisal. CNS Drugs 1995; 3: 194–208.
    • (1995) CNS Drugs , vol.3 , pp. 194-208
    • Schmidt, D.1    Gram, L.2
  • 102
    • 0036064611 scopus 로고    scopus 로고
    • Expression of the multidrug transporter p-glycoprotein in brain parenchyma of amygdala-kindled rats
    • Seegers U, Potschka H, Löscher W. Expression of the multidrug transporter P-glycoprotein in brain parenchyma of amygdala-kindled rats. Epilepsia 2002; 43: 675–684.
    • (2002) Epilepsia , vol.43 , pp. 675-684
    • Seegers, U.1    Potschka, H.2    Löscher, W.3
  • 103
    • 0018622931 scopus 로고
    • Reduction in polypharmacy for epilepsy
    • Shorvon S, Reynolds EH. Reduction in polypharmacy for epilepsy. Br Med J 1979; 2: 1023–1025.
    • (1979) Br Med J , vol.2 , pp. 1023-1025
    • Shorvon, S.1    Reynolds, E.H.2
  • 104
    • 0037431040 scopus 로고    scopus 로고
    • Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene abcb1
    • Siddiqui A, Kerb R, Weale ME, et al. Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. New Engl J Med 2003; 348: 1442–1448.
    • (2003) New Engl J Med , vol.348 , pp. 1442-1448
    • Siddiqui, A.1    Kerb, R.2    Weale, M.E.3
  • 105
    • 84921243570 scopus 로고
    • Lack of experimental interaction between vigabatrin and lamotrigine
    • Sills GJ, Thompson GT, Forrest G, et al. Lack of experimental interaction between vigabatrin and lamotrigine. Epilepsia 1993; 34(Suppl. 6): 92.
    • (1993) Epilepsia , vol.34 , pp. 92
    • Sills, G.J.1    Thompson, G.T.2    Forrest, G.3
  • 106
    • 0037399407 scopus 로고    scopus 로고
    • Mechanisms of antiepileptic drug resistance
    • Sisodiya SM. Mechanisms of antiepileptic drug resistance. Curr Opin Neurol 2003; 16: 197–201.
    • (2003) Curr Opin Neurol , vol.16 , pp. 197-201
    • Sisodiya, S.M.1
  • 107
    • 0036156280 scopus 로고    scopus 로고
    • Drug resistance in epilepsy: Expression of drug resistance proteins in common causes of refractory epilepsy
    • Sisodiya SM, Lin W-R, Harding BN, et al. Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy. Brain 2002; 1: 22–31.
    • (2002) Brain , vol.1 , pp. 22-31
    • Sisodiya, S.M.1    Lin, W.-R.2    Harding, B.N.3
  • 108
    • 0032495660 scopus 로고    scopus 로고
    • Lamotrigine and topiramate may be a useful combination
    • Stephen LJ, Sills GJ, Brodie MJ. Lamotrigine and topiramate may be a useful combination. Lancet 1998; 351: 958–959.
    • (1998) Lancet , vol.351 , pp. 958-959
    • Stephen, L.J.1    Sills, G.J.2    Brodie, M.J.3
  • 109
    • 0026494640 scopus 로고
    • Lamotrigine for generalized epilepsies (Letter)
    • Stewart J, Hughes E, Reynolds EH. Lamotrigine for generalized epilepsies (letter). Lancet 1992; 340: 1223.
    • (1992) Lancet , vol.340 , pp. 1223
    • Stewart, J.1    Hughes, E.2    Reynolds, E.H.3
  • 110
    • 0008857585 scopus 로고
    • Gamma-vinyl-gaba (Vigabatrin) and lamotrigine: Synergism in a refractory epilepsy?
    • Stolarek I, Blacklaw J, Thompson GG, et al. Gamma-vinyl-GABA (vigabatrin) and lamotrigine: synergism in a refractory epilepsy? Epilepsia 1993; 34(Suppl. 2): 108–109.
    • (1993) Epilepsia , vol.34 , pp. 108-109
    • Stolarek, I.1    Blacklaw, J.2    Thompson, G.G.3
  • 111
    • 0030297101 scopus 로고    scopus 로고
    • Vigabatrin vs carbamazepine monotherapy in newly diagnosed focal epilepsy: A randomised response conditional cross-over study
    • Tanganelli P, Regesta G. Vigabatrin vs carbamazepine monotherapy in newly diagnosed focal epilepsy: a randomised response conditional cross-over study. Epilepsy Res 1996; 25: 257–262.
    • (1996) Epilepsy Res , vol.25 , pp. 257-262
    • Tanganelli, P.1    Regesta, G.2
  • 112
    • 0002093754 scopus 로고
    • Carbamazepine versus valproate versus combined therapy for refractory partial complex seizures with secondary generalization
    • Walker JE, Koon R. Carbamazepine versus valproate versus combined therapy for refractory partial complex seizures with secondary generalization. Epilepsia 1988; 29: 693.
    • (1988) Epilepsia , vol.29 , pp. 693
    • Walker, J.E.1    Koon, R.2
  • 113
    • 0026597799 scopus 로고
    • Lamotrigine-induced carbamazepine toxicity: An interaction with carbamazepine-10, 11-epoxide
    • Warner T, Patsalos PN, Prevett M, et al. Lamotrigine-induced carbamazepine toxicity: an interaction with carbamazepine-10, 11-epoxide. Epilepsy Res 1992; 11: 147–150.
    • (1992) Epilepsy Res , vol.11 , pp. 147-150
    • Warner, T.1    Patsalos, P.N.2    Prevett, M.3
  • 114
    • 0029884831 scopus 로고    scopus 로고
    • Efficacy and safety of add-on divalproex sodium in the treatment of complex partial seizures
    • the M 88–194 Study Group
    • Willmore LJ, Shu V, Vallin B, the M 88–194 Study Group. Efficacy and safety of add-on divalproex sodium in the treatment of complex partial seizures. Neurology 1996; 46: 49–53.
    • (1996) Neurology , vol.46 , pp. 49-53
    • Willmore, L.J.1    Shu, V.2    Vallin, B.3
  • 115
    • 0001327436 scopus 로고
    • Evaluation of standard anticonvulsant therapy of 319 patients
    • Yahr MD, Sciarra D, Carter S. Evaluation of standard anticonvulsant therapy of 319 patients. J Am Med Assoc 1952; 150: 663–667.
    • (1952) J am Med Assoc , vol.150 , pp. 663-667
    • Yahr, M.D.1    Sciarra, D.2    Carter, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.