-
1
-
-
0028895740
-
MDR1 gene expression in brain of patients with medically intractable epilepsy
-
Tishler DM, Weinberg KI, Hinton DR, et al. MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia 1995;36:1-6.
-
(1995)
Epilepsia
, vol.36
, pp. 1-6
-
-
Tishler, D.M.1
Weinberg, K.I.2
Hinton, D.R.3
-
2
-
-
0032723612
-
Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy
-
Lazarowski A, Sevlever G, Taratuto A, et al. Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy. Pediatr Neurol 1999;21:731-734.
-
(1999)
Pediatr Neurol
, vol.21
, pp. 731-734
-
-
Lazarowski, A.1
Sevlever, G.2
Taratuto, A.3
-
3
-
-
0035814649
-
Multidrug-resistance protein 1 in focal cortical dysplasia
-
Sisodiya SM, Lin WR, Squier MV, et al. Multidrug-resistance protein 1 in focal cortical dysplasia. Lancet 2001;357:42-43.
-
(2001)
Lancet
, vol.357
, pp. 42-43
-
-
Sisodiya, S.M.1
Lin, W.R.2
Squier, M.V.3
-
4
-
-
0032972644
-
Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections
-
Zhang L, Ong WY, Lee T. Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections. Exp Brain Res 1999;126:509-516.
-
(1999)
Exp Brain Res
, vol.126
, pp. 509-516
-
-
Zhang, L.1
Ong, W.Y.2
Lee, T.3
-
5
-
-
0032879904
-
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
-
Schuetz JD, Connelly MC, Sun D, et al. MRP4: a previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat Med 1999;5:1048-1051.
-
(1999)
Nat Med
, vol.5
, pp. 1048-1051
-
-
Schuetz, J.D.1
Connelly, M.C.2
Sun, D.3
-
6
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001;293:876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
7
-
-
0028420272
-
Resistance to antibiotics mediated by target alterations
-
Spratt BG. Resistance to antibiotics mediated by target alterations. Science 1994;264:388-393.
-
(1994)
Science
, vol.264
, pp. 388-393
-
-
Spratt, B.G.1
-
8
-
-
0034680167
-
Molecular mechanisms that confer antibacterial drug resistance
-
Walsh C. Molecular mechanisms that confer antibacterial drug resistance. Nature 2000;406:775-781.
-
(2000)
Nature
, vol.406
, pp. 775-781
-
-
Walsh, C.1
-
9
-
-
0034914046
-
Do we need any more new antiepileptic drugs?
-
Brodie MJ. Do we need any more new antiepileptic drugs? Epilepsy Res 2001;45:3-6.
-
(2001)
Epilepsy Res
, vol.45
, pp. 3-6
-
-
Brodie, M.J.1
-
10
-
-
0025007629
-
New and potential anticonvulsants
-
Brodie MJ, Porter RJ. New and potential anticonvulsants. Lancet 1990;336:425-426.
-
(1990)
Lancet
, vol.336
, pp. 425-426
-
-
Brodie, M.J.1
Porter, R.J.2
-
11
-
-
0035036730
-
Carbamazepine is not a substrate for P-glycoprotein
-
Owen A, Pirmohamed M, Tettey JN, et al. Carbamazepine is not a substrate for P-glycoprotein. Br J Clin Pharmacol 2001;51:345-349.
-
(2001)
Br J Clin Pharmacol
, vol.51
, pp. 345-349
-
-
Owen, A.1
Pirmohamed, M.2
Tettey, J.N.3
-
12
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel AH, Wagenaar E, Mol CA, et al. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 1996;97:2517-2524.
-
(1996)
J Clin Invest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
-
13
-
-
0031966045
-
Sodium channels as molecular targets for antiepileptic drugs
-
Ragsdale DS, Avoli M. Sodium channels as molecular targets for antiepileptic drugs. Brain Res Brain Res Rev 1998;26:16-28.
-
(1998)
Brain Res Brain Res Rev
, vol.26
, pp. 16-28
-
-
Ragsdale, D.S.1
Avoli, M.2
-
15
-
-
0024372376
-
Phenytoin and carbamazepine: Potential-and frequency-dependent block of Na currents in mammalian myelinated nerve fibers
-
Schwarz JR, Grigat G. Phenytoin and carbamazepine: potential-and frequency-dependent block of Na currents in mammalian myelinated nerve fibers. Epilepsia 1989;30:286-294.
-
(1989)
Epilepsia
, vol.30
, pp. 286-294
-
-
Schwarz, J.R.1
Grigat, G.2
-
16
-
-
0021913947
-
Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells
-
Willow M, Gonoi T, Catterall WA. Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells. Mol Pharmacol 1985;27:549-558.
-
(1985)
Mol Pharmacol
, vol.27
, pp. 549-558
-
-
Willow, M.1
Gonoi, T.2
Catterall, W.A.3
-
17
-
-
0035310424
-
+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy
-
+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy. J Physiol 2001;532:205-216.
-
(2001)
J Physiol
, vol.532
, pp. 205-216
-
-
Sanabria, E.R.G.1
Su, H.2
Yaari, Y.3
-
18
-
-
0013950709
-
A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes
-
Margerison JH, Corsellis JAN. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain 1966;89:499-530.
-
(1966)
Brain
, vol.89
, pp. 499-530
-
-
Margerison, J.H.1
Corsellis, J.A.N.2
-
19
-
-
0344172752
-
Molecular neuropathology of human mesial temporal lobe epilepsy
-
Blumcke I, Beck H, Lie AA, et al. Molecular neuropathology of human mesial temporal lobe epilepsy. Epilepsy Res 1999;36:205-223.
-
(1999)
Epilepsy Res
, vol.36
, pp. 205-223
-
-
Blumcke, I.1
Beck, H.2
Lie, A.A.3
-
21
-
-
0027050718
-
Properties of two voltage-activated potassium currents in acutely isolated juvenile rat dentate gyrus granule cells
-
Beck H, Ficker E, Heinemann U. Properties of two voltage-activated potassium currents in acutely isolated juvenile rat dentate gyrus granule cells. J Neurophysiol 1992;68:2086-2099.
-
(1992)
J Neurophysiol
, vol.68
, pp. 2086-2099
-
-
Beck, H.1
Ficker, E.2
Heinemann, U.3
-
22
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
Hamill OP, Marty A, Neher E, et al. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 1981;391:85-100.
-
(1981)
Pflugers Arch
, vol.391
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
-
23
-
-
0035871089
-
+ channels in hippocampal granule cells, hilar neurons and basket cells
-
+ channels in hippocampal granule cells, hilar neurons and basket cells. J Physiol 2001;532:385-397.
-
(2001)
J Physiol
, vol.532
, pp. 385-397
-
-
Ellerkmann, R.K.1
Riazanski, V.2
Elger, C.E.3
-
24
-
-
0034094956
-
+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1
-
+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1. Eur J Neurosci 2000;12:2039-2048.
-
(2000)
Eur J Neurosci
, vol.12
, pp. 2039-2048
-
-
Kivi, A.1
Lehmann, T.N.2
Kovacs, R.3
-
25
-
-
0032546902
-
+]o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampus
-
+]o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampus. Neurosci Lett 1998;249:91-94.
-
(1998)
Neurosci Lett
, vol.249
, pp. 91-94
-
-
Gabriel, S.1
Kivi, A.2
Kovacs, R.3
-
26
-
-
0020545095
-
Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study
-
Turski WA, Cavalheiro EA, Schwarz M, et al. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res 1983;9:315-335.
-
(1983)
Behav Brain Res
, vol.9
, pp. 315-335
-
-
Turski, W.A.1
Cavalheiro, E.A.2
Schwarz, M.3
-
27
-
-
0006336164
-
+ currents in human dentate granule cells from epileptogenic tissue
-
+ currents in human dentate granule cells from epileptogenic tissue. Epilepsia 1999;40:401-407.
-
(1999)
Epilepsia
, vol.40
, pp. 401-407
-
-
Reckziegel, G.1
Beck, H.2
Schramm, J.3
-
28
-
-
0030949912
-
+ currents: Quantitative distinction from phenytoin and possible therapeutic implications
-
+ currents: quantitative distinction from phenytoin and possible therapeutic implications. Mol Pharmacol 1997;51:1077-1083.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 1077-1083
-
-
Kuo, C.C.1
Chen, R.S.2
Lu, L.3
-
29
-
-
0025827588
-
+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs
-
+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs. Mol Pharmacol 1991;40:756-765.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 756-765
-
-
Ragsdale, D.S.1
Scheuer, T.2
Catterall, W.A.3
-
31
-
-
0025732928
-
+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil
-
+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil. Brain Res 1991;548:41-49.
-
(1991)
Brain Res
, vol.548
, pp. 41-49
-
-
Backus, K.H.1
Pflimlin, P.2
Trube, G.3
-
32
-
-
0027507511
-
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells
-
Lang DG, Wang CM, Cooper BR. Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. J Pharmacol Exp Ther 1993;266:829-835.
-
(1993)
J Pharmacol Exp Ther
, vol.266
, pp. 829-835
-
-
Lang, D.G.1
Wang, C.M.2
Cooper, B.R.3
-
33
-
-
0032745927
-
Modulation of sodium currents in rat CA1 neurons by carbamazepine and valproate after kindling epileptogenesis
-
Vreugdenhil M, Wadman WJ. Modulation of sodium currents in rat CA1 neurons by carbamazepine and valproate after kindling epileptogenesis. Epilepsia 1999;40:1512-1522.
-
(1999)
Epilepsia
, vol.40
, pp. 1512-1522
-
-
Vreugdenhil, M.1
Wadman, W.J.2
-
35
-
-
0018126080
-
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients
-
Friis ML, Christiansen J, Hvidberg EF. Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients. Eur J Clin Pharmacol 1978;14:47-51.
-
(1978)
Eur J Clin Pharmacol
, vol.14
, pp. 47-51
-
-
Friis, M.L.1
Christiansen, J.2
Hvidberg, E.F.3
-
36
-
-
0027538206
-
Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in the serum: Analysis of autoptic specimens from 51 epileptic patients
-
Rambeck B, Schnabel R, May T, et al. Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in the serum: analysis of autoptic specimens from 51 epileptic patients. Ther Drug Monit 1993;15:91-98.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 91-98
-
-
Rambeck, B.1
Schnabel, R.2
May, T.3
-
37
-
-
0028836283
-
Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats
-
Leite JP, Cavalheiro EA. Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats. Epilepsy Res 1995;20:93-104.
-
(1995)
Epilepsy Res
, vol.20
, pp. 93-104
-
-
Leite, J.P.1
Cavalheiro, E.A.2
-
38
-
-
0000743599
-
Anticonvulsant effects of the novel antiepileptic drug levetiracetam in the rat pilocarpine model of temporal lobe epilepsy
-
Glien M, Brandt C, Potschka H, et al. Anticonvulsant effects of the novel antiepileptic drug levetiracetam in the rat pilocarpine model of temporal lobe epilepsy. Epilepsia 2001;42(suppl 7):268.
-
(2001)
Epilepsia
, vol.42
, Issue.SUPPL. 7
, pp. 268
-
-
Glien, M.1
Brandt, C.2
Potschka, H.3
-
39
-
-
0000983086
-
An animal model with spontaneous seizures: A new tool for testing the effects of antiepileptic compounds
-
Nissinen JPT, Pitkänen A. An animal model with spontaneous seizures: a new tool for testing the effects of antiepileptic compounds. Epilepsia 2000;41:136.
-
(2000)
Epilepsia
, vol.41
, pp. 136
-
-
Nissinen, J.P.T.1
Pitkänen, A.2
-
40
-
-
0026075949
-
Kindling as a model of drug-resistant partial epilepsy: Selection of phenytoin-resistant and nonresistant rats
-
Loscher W, Rundfeldt C. Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats. J Pharmacol Exp Ther 1991;258:483-489.
-
(1991)
J Pharmacol Exp Ther
, vol.258
, pp. 483-489
-
-
Loscher, W.1
Rundfeldt, C.2
-
41
-
-
0027242081
-
Pharmacological characterization of phenytoinresistent amygdala-kindled rats, a new model of drug-resistant partial epilepsy
-
Löscher W, Rundfeldt C, Hönack D. Pharmacological characterization of phenytoinresistent amygdala-kindled rats, a new model of drug-resistant partial epilepsy. Epilepsy Res 1993;15:207-219.
-
(1993)
Epilepsy Res
, vol.15
, pp. 207-219
-
-
Löscher, W.1
Rundfeldt, C.2
Hönack, D.3
-
42
-
-
0024320376
-
Amygdala-kindling as a model for chronic efficacy studies on antiepileptic drugs: Experiments with carbamazepine
-
Hönack D, Löscher W. Amygdala-kindling as a model for chronic efficacy studies on antiepileptic drugs: experiments with carbamazepine. Neuropharmacology 1989;28:599-610.
-
(1989)
Neuropharmacology
, vol.28
, pp. 599-610
-
-
Hönack, D.1
Löscher, W.2
-
43
-
-
0036144493
-
Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats
-
Jeub M, Beck H, Siep E, et al. Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats. Neuropharmacology 2002;42:107-116.
-
(2002)
Neuropharmacology
, vol.42
, pp. 107-116
-
-
Jeub, M.1
Beck, H.2
Siep, E.3
-
44
-
-
0035900333
-
P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
-
Potschka H, Fedrowitz M, Loscher W. P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport 2001;12:3557-3560.
-
(2001)
Neuroreport
, vol.12
, pp. 3557-3560
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
|