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Volumn 53, Issue 4, 2003, Pages 469-479

A novel mechanism underlying drug resistance in chronic epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; SODIUM CHANNEL;

EID: 0345382778     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.10473     Document Type: Article
Times cited : (209)

References (44)
  • 1
    • 0028895740 scopus 로고
    • MDR1 gene expression in brain of patients with medically intractable epilepsy
    • Tishler DM, Weinberg KI, Hinton DR, et al. MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia 1995;36:1-6.
    • (1995) Epilepsia , vol.36 , pp. 1-6
    • Tishler, D.M.1    Weinberg, K.I.2    Hinton, D.R.3
  • 2
    • 0032723612 scopus 로고    scopus 로고
    • Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy
    • Lazarowski A, Sevlever G, Taratuto A, et al. Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy. Pediatr Neurol 1999;21:731-734.
    • (1999) Pediatr Neurol , vol.21 , pp. 731-734
    • Lazarowski, A.1    Sevlever, G.2    Taratuto, A.3
  • 3
    • 0035814649 scopus 로고    scopus 로고
    • Multidrug-resistance protein 1 in focal cortical dysplasia
    • Sisodiya SM, Lin WR, Squier MV, et al. Multidrug-resistance protein 1 in focal cortical dysplasia. Lancet 2001;357:42-43.
    • (2001) Lancet , vol.357 , pp. 42-43
    • Sisodiya, S.M.1    Lin, W.R.2    Squier, M.V.3
  • 4
    • 0032972644 scopus 로고    scopus 로고
    • Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections
    • Zhang L, Ong WY, Lee T. Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections. Exp Brain Res 1999;126:509-516.
    • (1999) Exp Brain Res , vol.126 , pp. 509-516
    • Zhang, L.1    Ong, W.Y.2    Lee, T.3
  • 5
    • 0032879904 scopus 로고    scopus 로고
    • MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
    • Schuetz JD, Connelly MC, Sun D, et al. MRP4: a previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat Med 1999;5:1048-1051.
    • (1999) Nat Med , vol.5 , pp. 1048-1051
    • Schuetz, J.D.1    Connelly, M.C.2    Sun, D.3
  • 6
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001;293:876-880.
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3
  • 7
    • 0028420272 scopus 로고
    • Resistance to antibiotics mediated by target alterations
    • Spratt BG. Resistance to antibiotics mediated by target alterations. Science 1994;264:388-393.
    • (1994) Science , vol.264 , pp. 388-393
    • Spratt, B.G.1
  • 8
    • 0034680167 scopus 로고    scopus 로고
    • Molecular mechanisms that confer antibacterial drug resistance
    • Walsh C. Molecular mechanisms that confer antibacterial drug resistance. Nature 2000;406:775-781.
    • (2000) Nature , vol.406 , pp. 775-781
    • Walsh, C.1
  • 9
    • 0034914046 scopus 로고    scopus 로고
    • Do we need any more new antiepileptic drugs?
    • Brodie MJ. Do we need any more new antiepileptic drugs? Epilepsy Res 2001;45:3-6.
    • (2001) Epilepsy Res , vol.45 , pp. 3-6
    • Brodie, M.J.1
  • 10
    • 0025007629 scopus 로고
    • New and potential anticonvulsants
    • Brodie MJ, Porter RJ. New and potential anticonvulsants. Lancet 1990;336:425-426.
    • (1990) Lancet , vol.336 , pp. 425-426
    • Brodie, M.J.1    Porter, R.J.2
  • 11
    • 0035036730 scopus 로고    scopus 로고
    • Carbamazepine is not a substrate for P-glycoprotein
    • Owen A, Pirmohamed M, Tettey JN, et al. Carbamazepine is not a substrate for P-glycoprotein. Br J Clin Pharmacol 2001;51:345-349.
    • (2001) Br J Clin Pharmacol , vol.51 , pp. 345-349
    • Owen, A.1    Pirmohamed, M.2    Tettey, J.N.3
  • 12
    • 0029892497 scopus 로고    scopus 로고
    • P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
    • Schinkel AH, Wagenaar E, Mol CA, et al. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 1996;97:2517-2524.
    • (1996) J Clin Invest , vol.97 , pp. 2517-2524
    • Schinkel, A.H.1    Wagenaar, E.2    Mol, C.A.3
  • 13
    • 0031966045 scopus 로고    scopus 로고
    • Sodium channels as molecular targets for antiepileptic drugs
    • Ragsdale DS, Avoli M. Sodium channels as molecular targets for antiepileptic drugs. Brain Res Brain Res Rev 1998;26:16-28.
    • (1998) Brain Res Brain Res Rev , vol.26 , pp. 16-28
    • Ragsdale, D.S.1    Avoli, M.2
  • 15
    • 0024372376 scopus 로고
    • Phenytoin and carbamazepine: Potential-and frequency-dependent block of Na currents in mammalian myelinated nerve fibers
    • Schwarz JR, Grigat G. Phenytoin and carbamazepine: potential-and frequency-dependent block of Na currents in mammalian myelinated nerve fibers. Epilepsia 1989;30:286-294.
    • (1989) Epilepsia , vol.30 , pp. 286-294
    • Schwarz, J.R.1    Grigat, G.2
  • 16
    • 0021913947 scopus 로고
    • Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells
    • Willow M, Gonoi T, Catterall WA. Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells. Mol Pharmacol 1985;27:549-558.
    • (1985) Mol Pharmacol , vol.27 , pp. 549-558
    • Willow, M.1    Gonoi, T.2    Catterall, W.A.3
  • 17
    • 0035310424 scopus 로고    scopus 로고
    • +-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy
    • +-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy. J Physiol 2001;532:205-216.
    • (2001) J Physiol , vol.532 , pp. 205-216
    • Sanabria, E.R.G.1    Su, H.2    Yaari, Y.3
  • 18
    • 0013950709 scopus 로고
    • A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes
    • Margerison JH, Corsellis JAN. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain 1966;89:499-530.
    • (1966) Brain , vol.89 , pp. 499-530
    • Margerison, J.H.1    Corsellis, J.A.N.2
  • 19
    • 0344172752 scopus 로고    scopus 로고
    • Molecular neuropathology of human mesial temporal lobe epilepsy
    • Blumcke I, Beck H, Lie AA, et al. Molecular neuropathology of human mesial temporal lobe epilepsy. Epilepsy Res 1999;36:205-223.
    • (1999) Epilepsy Res , vol.36 , pp. 205-223
    • Blumcke, I.1    Beck, H.2    Lie, A.A.3
  • 21
    • 0027050718 scopus 로고
    • Properties of two voltage-activated potassium currents in acutely isolated juvenile rat dentate gyrus granule cells
    • Beck H, Ficker E, Heinemann U. Properties of two voltage-activated potassium currents in acutely isolated juvenile rat dentate gyrus granule cells. J Neurophysiol 1992;68:2086-2099.
    • (1992) J Neurophysiol , vol.68 , pp. 2086-2099
    • Beck, H.1    Ficker, E.2    Heinemann, U.3
  • 22
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • Hamill OP, Marty A, Neher E, et al. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 1981;391:85-100.
    • (1981) Pflugers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3
  • 23
    • 0035871089 scopus 로고    scopus 로고
    • + channels in hippocampal granule cells, hilar neurons and basket cells
    • + channels in hippocampal granule cells, hilar neurons and basket cells. J Physiol 2001;532:385-397.
    • (2001) J Physiol , vol.532 , pp. 385-397
    • Ellerkmann, R.K.1    Riazanski, V.2    Elger, C.E.3
  • 24
    • 0034094956 scopus 로고    scopus 로고
    • +]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1
    • +]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1. Eur J Neurosci 2000;12:2039-2048.
    • (2000) Eur J Neurosci , vol.12 , pp. 2039-2048
    • Kivi, A.1    Lehmann, T.N.2    Kovacs, R.3
  • 25
    • 0032546902 scopus 로고    scopus 로고
    • +]o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampus
    • +]o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampus. Neurosci Lett 1998;249:91-94.
    • (1998) Neurosci Lett , vol.249 , pp. 91-94
    • Gabriel, S.1    Kivi, A.2    Kovacs, R.3
  • 26
    • 0020545095 scopus 로고
    • Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study
    • Turski WA, Cavalheiro EA, Schwarz M, et al. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res 1983;9:315-335.
    • (1983) Behav Brain Res , vol.9 , pp. 315-335
    • Turski, W.A.1    Cavalheiro, E.A.2    Schwarz, M.3
  • 27
    • 0006336164 scopus 로고    scopus 로고
    • + currents in human dentate granule cells from epileptogenic tissue
    • + currents in human dentate granule cells from epileptogenic tissue. Epilepsia 1999;40:401-407.
    • (1999) Epilepsia , vol.40 , pp. 401-407
    • Reckziegel, G.1    Beck, H.2    Schramm, J.3
  • 28
    • 0030949912 scopus 로고    scopus 로고
    • + currents: Quantitative distinction from phenytoin and possible therapeutic implications
    • + currents: quantitative distinction from phenytoin and possible therapeutic implications. Mol Pharmacol 1997;51:1077-1083.
    • (1997) Mol Pharmacol , vol.51 , pp. 1077-1083
    • Kuo, C.C.1    Chen, R.S.2    Lu, L.3
  • 29
    • 0025827588 scopus 로고
    • + channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs
    • + channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs. Mol Pharmacol 1991;40:756-765.
    • (1991) Mol Pharmacol , vol.40 , pp. 756-765
    • Ragsdale, D.S.1    Scheuer, T.2    Catterall, W.A.3
  • 31
    • 0025732928 scopus 로고
    • + current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil
    • + current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil. Brain Res 1991;548:41-49.
    • (1991) Brain Res , vol.548 , pp. 41-49
    • Backus, K.H.1    Pflimlin, P.2    Trube, G.3
  • 32
    • 0027507511 scopus 로고
    • Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells
    • Lang DG, Wang CM, Cooper BR. Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells. J Pharmacol Exp Ther 1993;266:829-835.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 829-835
    • Lang, D.G.1    Wang, C.M.2    Cooper, B.R.3
  • 33
    • 0032745927 scopus 로고    scopus 로고
    • Modulation of sodium currents in rat CA1 neurons by carbamazepine and valproate after kindling epileptogenesis
    • Vreugdenhil M, Wadman WJ. Modulation of sodium currents in rat CA1 neurons by carbamazepine and valproate after kindling epileptogenesis. Epilepsia 1999;40:1512-1522.
    • (1999) Epilepsia , vol.40 , pp. 1512-1522
    • Vreugdenhil, M.1    Wadman, W.J.2
  • 35
    • 0018126080 scopus 로고
    • Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients
    • Friis ML, Christiansen J, Hvidberg EF. Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients. Eur J Clin Pharmacol 1978;14:47-51.
    • (1978) Eur J Clin Pharmacol , vol.14 , pp. 47-51
    • Friis, M.L.1    Christiansen, J.2    Hvidberg, E.F.3
  • 36
    • 0027538206 scopus 로고
    • Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in the serum: Analysis of autoptic specimens from 51 epileptic patients
    • Rambeck B, Schnabel R, May T, et al. Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in the serum: analysis of autoptic specimens from 51 epileptic patients. Ther Drug Monit 1993;15:91-98.
    • (1993) Ther Drug Monit , vol.15 , pp. 91-98
    • Rambeck, B.1    Schnabel, R.2    May, T.3
  • 37
    • 0028836283 scopus 로고
    • Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats
    • Leite JP, Cavalheiro EA. Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats. Epilepsy Res 1995;20:93-104.
    • (1995) Epilepsy Res , vol.20 , pp. 93-104
    • Leite, J.P.1    Cavalheiro, E.A.2
  • 38
    • 0000743599 scopus 로고    scopus 로고
    • Anticonvulsant effects of the novel antiepileptic drug levetiracetam in the rat pilocarpine model of temporal lobe epilepsy
    • Glien M, Brandt C, Potschka H, et al. Anticonvulsant effects of the novel antiepileptic drug levetiracetam in the rat pilocarpine model of temporal lobe epilepsy. Epilepsia 2001;42(suppl 7):268.
    • (2001) Epilepsia , vol.42 , Issue.SUPPL. 7 , pp. 268
    • Glien, M.1    Brandt, C.2    Potschka, H.3
  • 39
    • 0000983086 scopus 로고    scopus 로고
    • An animal model with spontaneous seizures: A new tool for testing the effects of antiepileptic compounds
    • Nissinen JPT, Pitkänen A. An animal model with spontaneous seizures: a new tool for testing the effects of antiepileptic compounds. Epilepsia 2000;41:136.
    • (2000) Epilepsia , vol.41 , pp. 136
    • Nissinen, J.P.T.1    Pitkänen, A.2
  • 40
    • 0026075949 scopus 로고
    • Kindling as a model of drug-resistant partial epilepsy: Selection of phenytoin-resistant and nonresistant rats
    • Loscher W, Rundfeldt C. Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats. J Pharmacol Exp Ther 1991;258:483-489.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 483-489
    • Loscher, W.1    Rundfeldt, C.2
  • 41
    • 0027242081 scopus 로고
    • Pharmacological characterization of phenytoinresistent amygdala-kindled rats, a new model of drug-resistant partial epilepsy
    • Löscher W, Rundfeldt C, Hönack D. Pharmacological characterization of phenytoinresistent amygdala-kindled rats, a new model of drug-resistant partial epilepsy. Epilepsy Res 1993;15:207-219.
    • (1993) Epilepsy Res , vol.15 , pp. 207-219
    • Löscher, W.1    Rundfeldt, C.2    Hönack, D.3
  • 42
    • 0024320376 scopus 로고
    • Amygdala-kindling as a model for chronic efficacy studies on antiepileptic drugs: Experiments with carbamazepine
    • Hönack D, Löscher W. Amygdala-kindling as a model for chronic efficacy studies on antiepileptic drugs: experiments with carbamazepine. Neuropharmacology 1989;28:599-610.
    • (1989) Neuropharmacology , vol.28 , pp. 599-610
    • Hönack, D.1    Löscher, W.2
  • 43
    • 0036144493 scopus 로고    scopus 로고
    • Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats
    • Jeub M, Beck H, Siep E, et al. Effect of phenytoin on sodium and calcium currents in hippocampal CA1 neurons of phenytoin-resistant kindled rats. Neuropharmacology 2002;42:107-116.
    • (2002) Neuropharmacology , vol.42 , pp. 107-116
    • Jeub, M.1    Beck, H.2    Siep, E.3
  • 44
    • 0035900333 scopus 로고    scopus 로고
    • P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
    • Potschka H, Fedrowitz M, Loscher W. P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport 2001;12:3557-3560.
    • (2001) Neuroreport , vol.12 , pp. 3557-3560
    • Potschka, H.1    Fedrowitz, M.2    Loscher, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.