The use of microsatellite instability, immunohistochemistry and other variables in determining the clinical significance of MLH1 and MSH2 unclassified variants in Lynch syndrome

Cancer Biomarkers

Volumn 2, Issue 1-2, 2006, Pages 11-27

  Lucci Cordisco, Emanuela ^a,c   Boccuto, Luigi ^b   Neri, Giovanni ^b   Genuardi, Maurizio ^c,d  

^a CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d FiorGen Foundation   (Italy)

Author keywords

colorectal cancer; functional assay; HNPCC; mismatch repair; mutation; polymorphism

Indexed keywords

CARRIER PROTEIN; MICROSATELLITE DNA; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN MSH2;

BIOSYNTHESIS; CHEMISTRY; CLASSIFICATION; COLORECTAL TUMOR; GENETIC VARIABILITY; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; REVIEW;

CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; VARIATION (GENETICS);

EID: 35348836941     PISSN: 15740153     EISSN: 18758592     Source Type: Journal    
DOI: 10.3233/CBM-2006-21-203     Document Type: Review

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