Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes

Cancer Research

Volumn 61, Issue 21, 2001, Pages 7719-7721

  Marra, Giancarlo ^a   D'Atri, Stefania ^b   Yan, Hai ^c   Perrera, Claudia ^a   Cannavo', Elda ^b   Vogelstein, Bert ^c   Jiricny, Josef ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CANCER SUSCEPTIBILITY; CHROMOSOME MUTATION; COLON CANCER; CONTROLLED STUDY; DIPLOIDY; DNA REPAIR; HAPLOIDY; HUMAN; HUMAN CELL; HYBRID CELL; MISSENSE MUTATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ALLELES; ANIMALS; BASE PAIR MISMATCH; CHROMOSOMES, HUMAN, PAIR 2; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR; DNA-BINDING PROTEINS; GENE SILENCING; HUMANS; HYBRID CELLS; MICE; MUTATION; MUTATION, MISSENSE; MUTS HOMOLOG 2 PROTEIN; PROTO-ONCOGENE PROTEINS;

EID: 0035502991     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Conversion of diploidy to haploidy
2. Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells
3. Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
4. Mismatch repair deficiency associated with overexpression of the MSH3 gene
5. Heteroduplex repair in extracts of human HeLa cells
6. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
7. 6-alkylguanine alkyltransferase activity in Chinese hamster V79 cells following selection with chloroethylating agents
8. hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSα
9. hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds
10. A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: Implications for clinical screening
11. The human MLHI cDNA complements DNA mismatch repair defects in Mlh 1-deficient mouse embryonic fibroblasts
12. DNA damage tolerance, mismatch repair and genome instability
13. Involvement of the mismatch repair system in temozolomide-induced apoptosis
14. Functional analysis of human MLHI mutations in Saccharomyces cerevisiae
15. The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer