Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining

Journal of Pathology

Volumn 207, Issue 4, 2005, Pages 385-395

  Mangold, Elisabeth ^a   Pagenstecher, Constanze ^a   Friedl, Waltraut ^a   Fischer, Hans Peter ^a   Merkelbach Bruse, Sabine ^a   Ohlendorf, Maike ^a   Friedrichs, Nicolaus ^a   Aretz, Stefan ^a   Buettner, Reinhard ^a   Propping, Peter ^a   Mathiak, Micaela ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

HNPCC; Immunohistochemistry; Microsatellite analysis; MLH1; MSH2

Indexed keywords

GENE PRODUCT; MICROSATELLITE DNA; PROTEIN MLH1; PROTEIN MLH2; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; COLORECTAL TUMOR; DIAGNOSTIC ACCURACY; DNA DETERMINATION; EXON; FALSE POSITIVE RESULT; FRAMESHIFT MUTATION; GENE DELETION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOTE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RISK ASSESSMENT; SENSITIVITY ANALYSIS;

CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MUTATIONAL ANALYSIS; GERM-LINE MUTATION; HETEROZYGOTE; HUMANS; MICROSATELLITE REPEATS; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 29744435357     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1858     Document Type: Article

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