-
1
-
-
33646577163
-
Genetics and biology of pancreatic ductal adenocarcinoma
-
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA: Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev 2006;20:1218-1249.
-
(2006)
Genes Dev
, vol.20
, pp. 1218-1249
-
-
Hezel, A.F.1
Kimmelman, A.C.2
Stanger, B.Z.3
Bardeesy, N.4
Depinho, R.A.5
-
2
-
-
0036944329
-
Emerging cellular and molecular themes in pancreatic cancer research
-
Urrutia R: Emerging cellular and molecular themes in pancreatic cancer research. Int J Gastrointest Cancer 2002;31:1-4.
-
(2002)
Int J Gastrointest Cancer
, vol.31
, pp. 1-4
-
-
Urrutia, R.1
-
4
-
-
0034094977
-
Molecular genetic alterations in ductal pancreatic adenocarcinomas
-
xi
-
Kern SE: Molecular genetic alterations in ductal pancreatic adenocarcinomas. Med Clin North Am 2000;84:691-695, xi.
-
(2000)
Med Clin North Am
, vol.84
, pp. 691-695
-
-
Kern, S.E.1
-
5
-
-
0032943591
-
The nuclear factorkappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
-
Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, Chiao PJ: The nuclear factorkappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 1999;5:119-127.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
Chiao, P.J.6
-
6
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW: NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;2:301-310.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
7
-
-
0038621384
-
Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death
-
Arlt A, Gehrz A, Muerkoster S, Vorndamm J, Kruse ML, Folsch UR, Schafer H: Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene 2003;22:3243-3251.
-
(2003)
Oncogene
, vol.22
, pp. 3243-3251
-
-
Arlt, A.1
Gehrz, A.2
Muerkoster, S.3
Vorndamm, J.4
Kruse, M.L.5
Folsch, U.R.6
Schafer, H.7
-
8
-
-
0035864344
-
Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin
-
Arlt A, Vorndamm J, Breitenbroich M, Folsch UR, Kalthoff H, Schmidt WE, Schafer H: Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin. Oncogene 2001;20:859-868.
-
(2001)
Oncogene
, vol.20
, pp. 859-868
-
-
Arlt, A.1
Vorndamm, J.2
Breitenbroich, M.3
Folsch, U.R.4
Kalthoff, H.5
Schmidt, W.E.6
Schafer, H.7
-
9
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal BB: Nuclear factor-kappaB: the enemy within. Cancer Cell 2004;6:203-208.
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwal, B.B.1
-
10
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett JR: Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J 1990;9:2431-2438.
-
(1990)
EMBO J
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
11
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
Doble BW, Woodgett JR: GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 2003;116:1175-1186.
-
(2003)
J Cell Sci
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
12
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995;378:785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
13
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P: Wnt signaling and cancer. Genes Dev 2000;14:1837-1851.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
14
-
-
0029664368
-
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
-
Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P: Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 1996;272:1023-1026.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
15
-
-
33646795341
-
-
Ougolkov AV, Billadeau DD: Targeting GSK-3: a promising approach for cancer therapy? Future Oncol 2006;2:91-100.
-
Ougolkov AV, Billadeau DD: Targeting GSK-3: a promising approach for cancer therapy? Future Oncol 2006;2:91-100.
-
-
-
-
16
-
-
23044444841
-
Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation
-
Shakoori A, Ougolkov A, Yu ZW, Zhang B, Modarressi MH, Billadeau DD, Mai M, Takahashi Y, Minamoto T: Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 2005;334:1365-1373.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1365-1373
-
-
Shakoori, A.1
Ougolkov, A.2
Yu, Z.W.3
Zhang, B.4
Modarressi, M.H.5
Billadeau, D.D.6
Mai, M.7
Takahashi, Y.8
Minamoto, T.9
-
17
-
-
16844374033
-
Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells
-
Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD: Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Res 2005;65:2076-2081.
-
(2005)
Cancer Res
, vol.65
, pp. 2076-2081
-
-
Ougolkov, A.V.1
Fernandez-Zapico, M.E.2
Savoy, D.N.3
Urrutia, R.A.4
Billadeau, D.D.5
-
18
-
-
33749015218
-
Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: Association with kinase activity and tumor dedifferentiation
-
Ougolkov AV, Fernandez-Zapico ME, Bilim VN, Smyrk TC, Chari ST, Billadeau DD: Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiation. Clin Cancer Res 2006;12:5074-5081.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5074-5081
-
-
Ougolkov, A.V.1
Fernandez-Zapico, M.E.2
Bilim, V.N.3
Smyrk, T.C.4
Chari, S.T.5
Billadeau, D.D.6
-
19
-
-
20344399386
-
Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells
-
Erdal E, Ozturk N, Cagatay T, Eksioglu-Demiralp E, Ozturk M: Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. Int J Cancer 2005;115:903-910.
-
(2005)
Int J Cancer
, vol.115
, pp. 903-910
-
-
Erdal, E.1
Ozturk, N.2
Cagatay, T.3
Eksioglu-Demiralp, E.4
Ozturk, M.5
-
20
-
-
33746239119
-
Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells
-
Cao Q, Lu X, Feng YJ: Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells. Cell Res 2006;16:671-677.
-
(2006)
Cell Res
, vol.16
, pp. 671-677
-
-
Cao, Q.1
Lu, X.2
Feng, Y.J.3
-
21
-
-
7644220896
-
Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth
-
Mazor M, Kawano Y, Zhu H, Waxman J, Kypta RM: Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth. Oncogene 2004;23:7882-7892.
-
(2004)
Oncogene
, vol.23
, pp. 7882-7892
-
-
Mazor, M.1
Kawano, Y.2
Zhu, H.3
Waxman, J.4
Kypta, R.M.5
-
22
-
-
33744476502
-
A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia
-
De Toni F, Racaud-Sultan C, Chicanne G, Mas VM, Cariven C, Mesange F, Salles JP, Demur C, Allouche M, Payrastre B, Manenti S, Ysebaert L: A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia. Oncogene 2006;25:3113-3122.
-
(2006)
Oncogene
, vol.25
, pp. 3113-3122
-
-
De Toni, F.1
Racaud-Sultan, C.2
Chicanne, G.3
Mas, V.M.4
Cariven, C.5
Mesange, F.6
Salles, J.P.7
Demur, C.8
Allouche, M.9
Payrastre, B.10
Manenti, S.11
Ysebaert, L.12
-
23
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR: Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 2000;406:86-90.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
24
-
-
0030890234
-
Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3
-
Beals CR, Sheridan CM, Turck CW, Gardner P, Crabtree GR: Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 1997;275:1930-1934.
-
(1997)
Science
, vol.275
, pp. 1930-1934
-
-
Beals, C.R.1
Sheridan, C.M.2
Turck, C.W.3
Gardner, P.4
Crabtree, G.R.5
-
25
-
-
34547114509
-
Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells
-
Ougolkov AV, Bone ND, Fernandez-Zapico ME, Kay NE, Billadeau DD: Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood 2007;110:735-742.
-
(2007)
Blood
, vol.110
, pp. 735-742
-
-
Ougolkov, A.V.1
Bone, N.D.2
Fernandez-Zapico, M.E.3
Kay, N.E.4
Billadeau, D.D.5
-
26
-
-
9644262497
-
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity
-
Buss H, Dorrie A, Schmitz ML, Frank R, Livingstone M, Resch K, Kracht M: Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem 2004;279:49571-49574.
-
(2004)
J Biol Chem
, vol.279
, pp. 49571-49574
-
-
Buss, H.1
Dorrie, A.2
Schmitz, M.L.3
Frank, R.4
Livingstone, M.5
Resch, K.6
Kracht, M.7
-
27
-
-
26444436331
-
IKKbeta phosphorylates p65 at S468 in transactivation domain 2
-
Schwabe RF, Sakurai H: IKKbeta phosphorylates p65 at S468 in transactivation domain 2. FASEB J 2005;19:1758-1760.
-
(2005)
FASEB J
, vol.19
, pp. 1758-1760
-
-
Schwabe, R.F.1
Sakurai, H.2
-
28
-
-
0036081578
-
Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes
-
Schwabe RF, Brenner DA: Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes. Am J Physiol Gastrointest Liver Physiol 2002;283:G204-G211.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Schwabe, R.F.1
Brenner, D.A.2
-
29
-
-
0141928780
-
Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability
-
Demarchi F, Bertoli C, Sandy P, Schneider C: Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability. J Biol Chem 2003;278:39583-39590.
-
(2003)
J Biol Chem
, vol.278
, pp. 39583-39590
-
-
Demarchi, F.1
Bertoli, C.2
Sandy, P.3
Schneider, C.4
-
30
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW: Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004;23:2369-2380.
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
31
-
-
25444530592
-
Glycogen synthase kinase 3beta functions to specify gene-specific, NFkappaB-dependent transcription
-
Steinbrecher KA, Wilson W 3rd, Cogswell PC, Baldwin AS: Glycogen synthase kinase 3beta functions to specify gene-specific, NFkappaB-dependent transcription. Mol Cell Biol 2005;25:8444-8455.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8444-8455
-
-
Steinbrecher, K.A.1
Wilson 3rd, W.2
Cogswell, P.C.3
Baldwin, A.S.4
-
32
-
-
33645772214
-
Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through IKK2
-
Vashisht Gopal YN, Arora TS, Van Dyke MW: Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through IKK2. EMBO Rep 2006;7:291-296.
-
(2006)
EMBO Rep
, vol.7
, pp. 291-296
-
-
Vashisht Gopal, Y.N.1
Arora, T.S.2
Van Dyke, M.W.3
|