메뉴 건너뛰기




Volumn 37, Issue SUPPL. 3, 2007, Pages

Murine models of primary biliary cirrhosis: Comparisons and contrasts

Author keywords

Auto immunity; Environmental immunity; Primary biliary cirrhosis; TGF ; Tolerance; Tregs

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; MITOCHONDRION ANTIBODY; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

EID: 35348818680     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2007.00226.x     Document Type: Conference Paper
Times cited : (16)

References (35)
  • 1
    • 0023267078 scopus 로고
    • Identification and specificity of a cDNA encoding the 70 kd mitochondrial antigen recognized in primary biliary cirrhosis
    • Gershwin ME, Mackay IR, Sturgess A, Coppel RL. Identification and specificity of a cDNA encoding the 70 kd mitochondrial antigen recognized in primary biliary cirrhosis. J Immunol 1987; 138: 3525-31.
    • (1987) J Immunol , vol.138 , pp. 3525-3531
    • Gershwin, M.E.1    Mackay, I.R.2    Sturgess, A.3    Coppel, R.L.4
  • 2
    • 0023772131 scopus 로고
    • The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase
    • Van de Water J, Gershwin ME, Leung P, Ansari A, Coppel RL. The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. J Exp Med 1988; 167: 1791-9.
    • (1988) J Exp Med , vol.167 , pp. 1791-1799
    • Van de Water, J.1    Gershwin, M.E.2    Leung, P.3    Ansari, A.4    Coppel, R.L.5
  • 3
    • 0028905099 scopus 로고
    • HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: Evidence of molecular mimicry in human autoimmune diseases
    • Shimoda S, Nakamura M, Ishibashi H, Hayashida K, Niho Y. HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: Evidence of molecular mimicry in human autoimmune diseases. J Exp Med 1995; 181: 1835-45.
    • (1995) J Exp Med , vol.181 , pp. 1835-1845
    • Shimoda, S.1    Nakamura, M.2    Ishibashi, H.3    Hayashida, K.4    Niho, Y.5
  • 4
    • 7844229417 scopus 로고    scopus 로고
    • Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis
    • Shimoda S, Van de Water J, Ansari A et al. Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis. J Clin Invest 1998; 102: 1831-40.
    • (1998) J Clin Invest , vol.102 , pp. 1831-1840
    • Shimoda, S.1    Van de Water, J.2    Ansari, A.3
  • 5
    • 0037033367 scopus 로고    scopus 로고
    • Identification of HLA-A2-restricted CD8 (+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells
    • Kita H, Lian ZX, Van de Water J et al. Identification of HLA-A2-restricted CD8 (+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells. J Exp Med 2002; 195: 113-23.
    • (2002) J Exp Med , vol.195 , pp. 113-123
    • Kita, H.1    Lian, Z.X.2    Van de Water, J.3
  • 6
    • 17544366379 scopus 로고    scopus 로고
    • Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis
    • Reynoso-Paz S, Leung PS, Van De Water J et al. Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis. Hepatology 2000; 31: 24-9.
    • (2000) Hepatology , vol.31 , pp. 24-29
    • Reynoso-Paz, S.1    Leung, P.S.2    Van De Water, J.3
  • 7
    • 0033754620 scopus 로고    scopus 로고
    • Mucosal immunity and primary biliary cirrhosis: Presence of antimitochondrial antibodies in urine
    • Tanaka A, Nalbandian G, Leung PS et al. Mucosal immunity and primary biliary cirrhosis: Presence of antimitochondrial antibodies in urine. Hepatology 2000; 32: 910-15.
    • (2000) Hepatology , vol.32 , pp. 910-915
    • Tanaka, A.1    Nalbandian, G.2    Leung, P.S.3
  • 8
    • 0034953329 scopus 로고    scopus 로고
    • Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis
    • Odin JA, Huebert RC, Casciola-Rosen L, LaRusso NF, Rosen A. Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis. J Clin Invest 2001; 108: 223-32.
    • (2001) J Clin Invest , vol.108 , pp. 223-232
    • Odin, J.A.1    Huebert, R.C.2    Casciola-Rosen, L.3    LaRusso, N.F.4    Rosen, A.5
  • 9
    • 0034031785 scopus 로고    scopus 로고
    • Primary biliary cirrhosis: An orchestrated immune response against epithelial cells
    • Gershwin ME, Ansari AA, Mackay IR et al. Primary biliary cirrhosis: An orchestrated immune response against epithelial cells. Immunol Rev 2000; 174: 210-25.
    • (2000) Immunol Rev , vol.174 , pp. 210-225
    • Gershwin, M.E.1    Ansari, A.A.2    Mackay, I.R.3
  • 10
    • 0036139024 scopus 로고    scopus 로고
    • Contribution to antimitochondrial antibody production: Cleavage of pyruvate dehydrogenase complex-E2 by apoptosis-related proteases
    • Matsumura S, Van De Water J, Kita H et al. Contribution to antimitochondrial antibody production: Cleavage of pyruvate dehydrogenase complex-E2 by apoptosis-related proteases. Hepatology 2002; 35: 14-22.
    • (2002) Hepatology , vol.35 , pp. 14-22
    • Matsumura, S.1    Van De Water, J.2    Kita, H.3
  • 11
    • 0035422204 scopus 로고    scopus 로고
    • Genomic analysis of differentially expressed genes in liver and biliary epithelial cells of patients with primary biliary cirrhosis
    • Tanaka A, Leung PS, Kenny TP et al. Genomic analysis of differentially expressed genes in liver and biliary epithelial cells of patients with primary biliary cirrhosis. J Autoimmun 2001; 17: 89-98.
    • (2001) J Autoimmun , vol.17 , pp. 89-98
    • Tanaka, A.1    Leung, P.S.2    Kenny, T.P.3
  • 12
    • 0030663215 scopus 로고    scopus 로고
    • Enhanced apoptosis relates to bile duct loss in primary biliary cirrhosis
    • Harada K, Ozaki S, Gershwin ME, Nakanuma Y. Enhanced apoptosis relates to bile duct loss in primary biliary cirrhosis. Hepatology 1997; 26: 1399-405.
    • (1997) Hepatology , vol.26 , pp. 1399-1405
    • Harada, K.1    Ozaki, S.2    Gershwin, M.E.3    Nakanuma, Y.4
  • 13
    • 0035451120 scopus 로고    scopus 로고
    • Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: Connecting xenobiotics with primary biliary cirrhosis
    • Long SA, Quan C, Van de Water J et al. Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: Connecting xenobiotics with primary biliary cirrhosis. J Immunol 2001; 167: 2956-63.
    • (2001) J Immunol , vol.167 , pp. 2956-2963
    • Long, S.A.1    Quan, C.2    Van de Water, J.3
  • 14
    • 0038559882 scopus 로고    scopus 로고
    • Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies
    • Leung PS, Quan C, Park O et al. Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. J Immunol 2003; 170: 5326-32.
    • (2003) J Immunol , vol.170 , pp. 5326-5332
    • Leung, P.S.1    Quan, C.2    Park, O.3
  • 16
    • 33746210257 scopus 로고    scopus 로고
    • Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice
    • Oertelt S, Lian ZX, Cheng CM et al. Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice. J Immunol 2006; 177: 1655-60.
    • (2006) J Immunol , vol.177 , pp. 1655-1660
    • Oertelt, S.1    Lian, Z.X.2    Cheng, C.M.3
  • 17
    • 33751002069 scopus 로고    scopus 로고
    • IL-2 Receptor α-/-mice and the development of primary biliary cirrhosis
    • Nov
    • Wakabayashi KLZ, Moritoki Y, Lan R et al. IL-2 Receptor α-/-mice and the development of primary biliary cirrhosis. Hepatology 2006 Nov; 44 (5): 1240-9.
    • (2006) Hepatology , vol.44 , Issue.5 , pp. 1240-1249
    • Wakabayashi, K.L.Z.1    Moritoki, Y.2    Lan, R.3
  • 18
    • 4043129586 scopus 로고    scopus 로고
    • Genetic control of autoimmunity: Protection from diabetes, but spontaneous autoimmune biliary disease in a nonobese diabetic congenic strain
    • Koarada S, Wu Y, Fertig N et al. Genetic control of autoimmunity: protection from diabetes, but spontaneous autoimmune biliary disease in a nonobese diabetic congenic strain. J Immunol 2004; 173: 2315-23.
    • (2004) J Immunol , vol.173 , pp. 2315-2323
    • Koarada, S.1    Wu, Y.2    Fertig, N.3
  • 19
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 1992; 359: 693-9.
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3
  • 20
    • 0027500836 scopus 로고
    • Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: Aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype
    • Geiser AG, Letterio JJ, Kulkarni AB et al. Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: Aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype. Proc Natl Acad Sci USA 1993; 90: 9944-8.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9944-9948
    • Geiser, A.G.1    Letterio, J.J.2    Kulkarni, A.B.3
  • 21
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik L, Flavell RA. Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 2000; 12: 171-81.
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 23
    • 22544431621 scopus 로고    scopus 로고
    • The role of Fas in the immune system biology of IL-2R alpha knockout mice: Interplay among regulatory T cells, inflammation, hemopoiesis, and apoptosis
    • Sharma R, Bagavant H, Jarjour WN, Sung SS, Ju ST. The role of Fas in the immune system biology of IL-2R alpha knockout mice: Interplay among regulatory T cells, inflammation, hemopoiesis, and apoptosis. J Immunol 2005; 175: 1965-73.
    • (2005) J Immunol , vol.175 , pp. 1965-1973
    • Sharma, R.1    Bagavant, H.2    Jarjour, W.N.3    Sung, S.S.4    Ju, S.T.5
  • 24
    • 33747801470 scopus 로고    scopus 로고
    • IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
    • Zorn E, Nelson EA, Mohseni M et al. IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo. Blood 2006; 108: 1571-9.
    • (2006) Blood , vol.108 , pp. 1571-1579
    • Zorn, E.1    Nelson, E.A.2    Mohseni, M.3
  • 25
    • 2442637772 scopus 로고    scopus 로고
    • Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
    • Thornton AM, Donovan EE, Piccirillo CA, Shevach EM. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J Immunol 2004; 172: 6519-23.
    • (2004) J Immunol , vol.172 , pp. 6519-6523
    • Thornton, A.M.1    Donovan, E.E.2    Piccirillo, C.A.3    Shevach, E.M.4
  • 26
    • 33646000803 scopus 로고    scopus 로고
    • Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis
    • Lan RY, Cheng C, Lian ZX et al. Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis. Hepatology 2006; 43: 729-37.
    • (2006) Hepatology , vol.43 , pp. 729-737
    • Lan, R.Y.1    Cheng, C.2    Lian, Z.X.3
  • 27
    • 20144363210 scopus 로고    scopus 로고
    • Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis
    • Kikuchi K, Lian ZX, Kimura Y et al. Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis. J Autoimmun 2005; 24: 347-52.
    • (2005) J Autoimmun , vol.24 , pp. 347-352
    • Kikuchi, K.1    Lian, Z.X.2    Kimura, Y.3
  • 28
    • 25844471675 scopus 로고    scopus 로고
    • Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis
    • Mao TK, Lian ZX, Selmi C et al. Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis. Hepatology 2005; 42: 802-8.
    • (2005) Hepatology , vol.42 , pp. 802-808
    • Mao, T.K.1    Lian, Z.X.2    Selmi, C.3
  • 29
    • 2342541212 scopus 로고    scopus 로고
    • Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis
    • Matsumura S, Van De Water J, Leung P et al. Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. Hepatology 2004; 39: 1415-22.
    • (2004) Hepatology , vol.39 , pp. 1415-1422
    • Matsumura, S.1    Van De Water, J.2    Leung, P.3
  • 30
    • 0031883604 scopus 로고    scopus 로고
    • Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: In situ and culture study
    • Yasoshima M, Kono N, Sugawara H et al. Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: In situ and culture study. Lab Invest 1998; 78: 89-100.
    • (1998) Lab Invest , vol.78 , pp. 89-100
    • Yasoshima, M.1    Kono, N.2    Sugawara, H.3
  • 31
    • 0030977867 scopus 로고    scopus 로고
    • Cytokines in primary biliary cirrhosis
    • Berg PA, Klein R, Rocken M. Cytokines in primary biliary cirrhosis. Semin Liver Dis 1997; 17: 115-23.
    • (1997) Semin Liver Dis , vol.17 , pp. 115-123
    • Berg, P.A.1    Klein, R.2    Rocken, M.3
  • 32
    • 33646673596 scopus 로고    scopus 로고
    • NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis
    • Irie J, Wu Y, Wicker LS et al. NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis. J Exp Med 2006; 203: 1209-19.
    • (2006) J Exp Med , vol.203 , pp. 1209-1219
    • Irie, J.1    Wu, Y.2    Wicker, L.S.3
  • 33
    • 34247598749 scopus 로고    scopus 로고
    • Balancing autoaggressive and protective T cell responses
    • Mar-May
    • Abbas AK, Lohr J, Knoechel B. Balancing autoaggressive and protective T cell responses. J Autoimmun 2007 Mar-May; 28 (2-3): 59-61.
    • (2007) , vol.28 , Issue.2-3 , pp. 59-61
    • Abbas, A.K.1    Lohr, J.2    Knoechel, B.3
  • 35
    • 34247633493 scopus 로고    scopus 로고
    • The X and why of xenobiotics in primary biliary cirrhosis
    • Mar-May
    • Rieger R, Gershwin ME. The X and why of xenobiotics in primary biliary cirrhosis. J Autoimmun 2007 Mar-May; 28 (2-3): 76-84.
    • (2007) J Autoimmun , vol.28 , Issue.2-3 , pp. 76-84
    • Rieger, R.1    Gershwin, M.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.