Vascular adaptations to hypoxia: Molecular and cellular mechanisms regulating vascular tone

Essays in Biochemistry

Volumn 43, Issue , 2007, Pages 105-119

  Paffett, Michael L ^a   Walker, Benjimen R ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN PAPILLOMAVIRUS;

CALCIUM; OXYGEN; POTASSIUM; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL; ANOXIA; BIOLOGICAL MODEL; BLOOD VESSEL; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PATHOLOGY; PULMONARY ARTERY; REVIEW;

ANIMALS; ANOXIA; BLOOD VESSELS; CALCIUM; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HUMANS; MITOCHONDRIA; MODELS, BIOLOGICAL; NADPH OXIDASE; OXIDATION-REDUCTION; OXYGEN; POTASSIUM; PULMONARY ARTERY; REACTIVE OXYGEN SPECIES;

EID: 35248821829     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSE0430105     Document Type: Article

References (47)

1. 2-regulated gene expression. FASEB J. 16, 1151-1162
2. Lando, D., Peet, D.J., Gorman, J.J., Whelan, D.A., Whitelaw, M.L & Bruick, R.K. (2002) FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 16, 1466-1471
3. Semenza, G.L. (2000) Oxygen-regulated transcription factors and their role in pulmonary disease. Respir. Res. 1, 159-162
4. BelAiba, R.S., Djordjevic, T., Bonello, S., Flugel, D., Hess, J., Kietzmann, T. & Gorlach, A. (2004) Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells. Biol. Chem. 385, 249-257
5. Gorlach, A., Diebold, I., Schini-Kerth, V.B., Berchner-Pfannschmidt, U., Roth, U., Brandes, R.P., Kietzmann, T. & Busse, R. (2001) Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: role of the p22(phox)-containing NADPH oxidase. Circ. Res. 89, 47-54
6. Wolin, M.S., Ahmad, M. & Gupte, S.A. (2005) Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH. Am. J. Physiol. Lung Cell. Mol. Physiol. 289, L159-L173
7. 2+ activation of the NADPH oxidase 5 (NOX5). J. Biol. Chem. 279, 18583-18591
8. Cheng, G., Ritsick, D. & Lambeth, J.D. (2004) Nox3 regulation by NOXOI, p47phox, and p67phox. J. Biol. Chem. 279, 34250-34255
9. Geiszt, M., Lekstrom, K., Witta, J. & Leto, T.L. (2003) Proteins homologous to p47phox and p67phox support Superoxide production by NAD(P)H oxidase 1 in colon epithelial cells. J. Biol. Chem. 278, 20006-20012
10. Lassegue, B., Sorescu, D., Szocs, K., Yin, Q., Akers, M., Zhang, Y., Grant, S.L., Lambeth, J.D. & Griendling, K.K. (2001) Novel gp91 (phox) homologues in vascular smooth muscle cells: nox1 mediates angiotensin ll-induced Superoxide formation and redox-sensitive signaling pathways. Circ. Res. 88, 888-894
11. Patterson, C., Ruef, J., Madamanchi, N.R., Barry-Lane, P., Hu, Z., Horaist, C., Ballinger, C.A., Brasier, A.R., Bode, C. & Runge, M.S. (1999) Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47(phox) may participate in forming this oxidase in vitro and in vivo. J. Biol. Chem. 274, 19814-19822
12. McCoubrey, Jr, W.K., Huang, T.J. & Maines, M.D. (1997) Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur. J. Biochem. 247, 725-732
13. Morita, T., Perrella, M.A., Lee, M.E. & Kourembanas, S. (1995) Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl. Acad Sci. U.S.A. 92, 1475-1479
14. Gagov, H., Kadinov, B., Hristov, K., Boev, K., Itzev, D., Bolton, T. & Duridanova, D. (2003) Role of constitutively expressed heme oxygenase-2 in the regulation of guinea pig coronary artery tone. Pflugen Arch. 446, 412-421
15. Wijayanti, N., Kietzmann, T. & Immenschuh, S. (2005) Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B., p38-dependent signaling pathway in monocytes. J. Biol. Chem. 280, 21820-21829
16. Hartsfield, C.L., Alam, J. & Choi, A.M. (1998) Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate. FASEB J. 12, 1675-1682
17. Cheng, P.Y., Lee, Y.M., Shih, N.L., Chen, Y.C. & Yen, M.H. (2006) Heme oxygenase-1 contributes to the cytoprotection of a-lipoic acid via activation of p44/42 mitogen-activated protein kinase in vascular smooth muscle cells. Free Radical Biol. Med. 40, 1313-1322
18. Matsumoto, H., Ishikawa, K., Itabe, H. & Maruyama, Y. (2006) Carbon monoxide and bilirubin from heme oxygenase-1 suppresses reactive oxygen species generation and plasminogen activator inhibitor-1 induction. Mol. Cell Biochem. 291, 21-28
19. Abraham, N.G. & Kappas, A. (2005) Heme oxygenase and the cardiovascular-renal system. Free Radical Biol. Med 39, 1-25
20. Michelakis, E.D., Hampl, V., Nsair, A., Wu, X., Harry, G., Haromy, A., Gurtu, R. & Archer, S.L. (2002) Diversity in mitochondrial function explains differences in vascular oxygen sensing. Circ. Res. 90, 1307-1315
21. Freeman, B.A. & Crapo, J.D. (1981) Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J. Biol. Chem. 256, 10986-10992
22. Gupte, S.A., Kaminski, P.M., Floyd, B., Agarwal, R., Ali, N., Ahmad, M., Edwards, J. & Wolin, M.S. (2005) Cytosolic NADPH may regulate differences in basal Nox oxidase-derived Superoxide generation in bovine coronary and pulmonary arteries. Am. J. Physiol Heart Circ. Physiol. 288, H13-H21
23. Gupte, S.A., Arshad, M., Viola, S., Kaminski, P.M., Ungvari, Z., Rabbani, G., Koller, A. & Wolin, M.S. (2003) Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries. Am. J. Physiol Heart Circ. Physiol. 285, H2316-H2326
24. Marshall, C., Mamary, A.J., Verhoeven, A.J. & Marshall, B.E. (1996) Pulmonary artery NADPH-oxidase is activated in hypoxic pulmonary vasoconstriction. Am. J. Respir. Cell Mol. Biol. 15, 633-644
25. Liu, J.Q., Zelko, I.N., Erbynn, E.M., Sham, J.S. & Folz, R.J. (2006) Hypoxic pulmonary hypertension: role of Superoxide and NADPH oxidase (gp91 phox). Am. J. Physiol. Lung Cell Mol. Physiol. 290, L2-L10
26. Waypa, G.B., Guzy, R., Mungai, P.T., Mack, M.M., Marks, J.D., Roe, M.W. & Schumacker, P.T. (2006) Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circ. Res. 99, 970-978
27. Waypa, G.B., Chandel, N.S. & Schumacker, P.T. (2001) Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing. Circ. Res. 88, 1259-1266
28. 2 sensor in rat pulmonary vasculature. Circ. Res. 73, 1100-1112
29. Paky, A., Michael, J.R., Burke-Wolin, T.M., Wolin, M.S. & Gurtner, G.H. (1993) Endogenous production of Superoxide by rabbit lungs: effects of hypoxia or metabolic inhibitors. J. Appl. Physiol. 74, 2868-2874
30. + channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ. Res. 95, 308-318
31. Olschewski, A., Hong, Z., Peterson, D.A., Nelson, D.P., Porter, V.A. & Weir, E.K. (2004) Opposite effects of redox status on membrane potential, cytosolic calcium, and tone in pulmonary arteries and ductus arteriosus. Am. J. Physiol. Lung Cell Mol. Physiol. 286, L15-L22
32. Wilson, H.L., Dipp, M., Thomas, J.M., Lad, C., Galione, A. & Evans, A.M. (2001) ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor: a primary role for cyclic ADP-ribose in hypoxic pulmonary vasoconstriction. J. Biol. Chem. 276, 11180-11188
33. Snetkov, V.A., Aaronson, P.I., Ward, J.P., Knock, G.A. & Robertson, T.P. (2003) Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat. Br. J. Pharmacol. 140, 97-106
34. 2+ sensitization during sustained hypoxic pulmonary vasoconstriction is endothelium dependent. Am. J. Physiol. Lung Cell Mol. Physiol. 284, L1121-L1126
35. Liu, Q., Sham, J.S., Shimoda, L.A. & Sylvester, J.T. (2001) Hypoxic constriction of porcine distal pulmonary arteries: endothelium and endothelin dependence. Am. J. Physiol. Lung Cell Mol. Physiol. 280, L856-L865
36. Stenmark, K.R. & Mecham, R.P. (1997) Cellular and molecular mechanisms of pulmonary vascular remodeling. Annu. Rev. Physiol. 59, 89-144
37. Klemm, D.J., Watson, P.A., Frid, M.G., Dempsey, B.C., Schaack, J., Colton, LA., Nesterova, A., Stenmark, K.R. & Reusch, J.E. (2001) cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J. Biol. Chem. 276, 46132-46141
38. Barbera, J.A., Riverola, A., Roca, J., Ramirez, J., Wagner, P.D., Ros, D., Wiggs, B.R. & Rodriguez-Roisin, R. (1994) Pulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary disease. Am. J. Respir. Crit Care Med. 149, 423-429
39. Peinado, V.I., Barbera, J.A., Ramirez, J., Gomez, F.P., Roca, J., Jover, L., Gimferrer, J.M. & Rodriguez-Roisin, R. (1998) Endothelial dysfunction in pulmonary arteries of patients with mild COPD. Am. J. Physiol. 274, L908-L913
40. Chen, Y.F., Feng, J.A., Li, P., Xing, D., Zhang, Y., Serra, R., Ambalavanan, N., Majid-Hassan, E. & Oparil, S. (2006) Dominant negative mutation of the TGF-β receptor blocks hypoxia-induced pulmonary vascular remodeling. J. Appl. Physiol. 100, 564-571
41. Stenmark, K.R., Gerasimovskaya, E., Nemenoff, R.A. & Das, M. (2002) Hypoxic activation of adventitial fibroblasts: role in vascular remodeling. Chest 122, 326S-334S
42. Naik, J.S., Earley, S., Resta, T.C. & Walker, B.R. (2005) Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction. J. Appl. Physiol. 98, 1119-1124
43. Sweeney, M. & Yuan, J.X. (2000) Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels. Respir. Res. 1, 40-48
44. Platoshyn, O., Yu, Y., Golovina, VA, McDaniel, S.S., Krick, S., Li, L., Wang, J.Y., Rubin, L.J. & Yuan, J.X. (2001) Chronic hypoxia decreases K(V) channel expression and function in pulmonary artery myocytes. Am. J. Physiol. Lung Cell Mol. Physiol. 280, L801-L812
45. + channel activity and enhances survival in vascular smooth muscle cells. Am. J. Physiol. Cell Physiol. 281, C157-C165
46. Fagan, K.A., Oka, M., Bauer, N.R., Gebb, S.A., Ivy, D.D., Morris, K.G. & McMurtry, I.F. (2004) Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am. J. Phpiol. Lung Cell Mol. Physiol. 287, L656-L664
47. Hyvelin, J.M., Howell, K., Nichol, A., Costello, C.M., Preston, R.J. & McLoughlin, P. (2005) Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ. Res. 97, 185-191