Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation

Brain Research

Volumn 1176, Issue 1, 2007, Pages 1-10

  Rösner, Harald ^a   Möller, Wolfgang ^a   Wassermann, Torsten ^a   Mihatsch, Julia ^a   Blum, Martin ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Actin; Blebbistatin; Microtubules; Myosin; Neurite outgrowth

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; BLEBBISTATIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN II;

ACTIN MYOSIN INTERACTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICKEN; CONTROLLED STUDY; EMBRYO; FIBROBLAST; MICROTUBULE; MUSCLE CONTRACTILITY; NERVE CELL GROWTH; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ACTOMYOSIN; AMIDES; ANIMALS; CENTRAL NERVOUS SYSTEM; CHICK EMBRYO; CONTRACTILE PROTEINS; CYTOSKELETAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FIBRONECTINS; GROWTH CONES; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; LAMININ; MICROTUBULES; NEURAL PATHWAYS; NEURITES; NEUROGENESIS; NOCODAZOLE; PACLITAXEL; PSEUDOPODIA; PYRIDINES; RHO GTP-BINDING PROTEINS; TUBULIN MODULATORS;

EID: 35148842992     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.07.081     Document Type: Article

References (43)

1. Allingham J.S., Smith R., and Ragment I. The structural basis of blebbistatin inhibition and specificity for myosinII. Nat. Struct. Mol. Biol. 12 (2005) 378-379
2. Brandt R. Cytoskeletal mechanisms of axon outgrowth and pathfinding. Cell Tissue Res. 292 (1998) 181-189
3. Bray D., and White J.G. Cortical flow in animal cells. Science 239 (1988) 883-888
4. Bridgman P.C., Dave S., Asnes C.F., Tullio A.N., and Adelstein R.S. Myosin IIB is required for growth cone motility. J. Neurosci. 21 (2001) 6159-6169
5. Brown J., and Bridgman P.C. The role of myosin II in axonal outgrowth. J. Histochem. Cytochem. 51 (2003) 421-428
6. Brown M.E., and Bridgman P.C. Retrograde flow is increased in growth cones from myosin IIB knockout mice. J. Cell Sci. 116 (2003) 1087-1094
7. Brown M.E., and Bridgman P.C. Myosin function in nervous and sensory systems. J. Neurobiol. 58 (2004) 118-130
8. Dent E.W., and Kalil K. Axon branching requires interactions between dynamic microtubules and actin filaments. J. Neurosci. 21 (2001) 9757-9769
9. Diefenbach T.J., Latham V.M., Yimlamai D., Liu C.A., Herman I.M., and Jay D.G. Myosin 1c and myosin IIB serve opposing roles in lamellipodial dynamics of the neuronal growth cone. J. Cell Biol. 158 (2002) 1207-1217
10. Dontchev V.D., and Letourneau P.C. Growth cones integrate signaling from multiple guidance cues. J. Histochem. Cytochem. 51 (2003) 435-444
11. Forscher P., and Smith S.J. Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone. J. Cell Biol. 107 (1988) 1505-1516
12. Gehler S., Shaw A.E., Sarmiere P.D., Bamburg J.R., and Letourneau P.C. Brain derived neurotropic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin. J. Neurosci. 24 (2004) 10741-10749
13. Gehler S., Gallo G., Veien E., and Letourneau P.C. p75 Neurotrophin receptor signalling regulates growth cone filopodial dynamics through modulating RhoA activity. J. Neurosci. 24 (2004) 4363-4372
14. Gordon-Weeks P.R. Microtubules and growth cone function. J. Neurobiol. 8 (2004) 70-83
15. Gordon-Weeks P.R. Actin dynamics: re-drawing the map. Nat. Cell Biol. 6 (2004) 390-391
16. Heidemann S.R., and Buxbaum R.E. Cell crawling: first the motor, now the transmission. J. Cell Biol. 141 (1998) 1-4
17. Hirose M., Ishzaki T., Wantanabe N., Uehata M., Kranenburg O., Moolenaar W.H., Matsumura F., Maekawa M., Bito H., and Narumiya S. Molecular dissection of the rho-associated protein kinase (p160ROCK)-regulated neurite remodelling in neuroblastoma N1E-115 cells. J. Cell Biol. 141 (1998) 1625-1636
18. Ishizaki T., Morishima Y., Okamoto M., Furuyashiki T., Kato T., and Narumiya S. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia 1. Nat. Cell Biol. 3 (2001) 8-14
19. Jay D.G. The clutch hypothesis revisited: ascribing the roles of actin-associated proteins in filopodial protrusion in the nerve growth cone. J. Neurobiol. 44 (2000) 114-125
20. Kimura K., Ito M., Amano M., Chihara K., Fukata Y., Nakafuku M., Yamamori B., Feng J., Nakano T., Okawa K., Iwamatsu A., and Kaibuchi K. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273 (1996) 245-248
21. Kornack D.R., and Giger R.J. Probing microtubule + Tips. Regulation of axon branching. Curr. Opin. Neurobiol. 15 (2005) 58-66
22. Kovacs M., Tóth J., Hetényi C., Málnási-Csizmadia A., and Sellers J.R. Mechanism of blebbistatin inhibition of myosinII. J. Biol. Chem. 279 (2004) 35557-35563
23. Leung D.L., Green K.J., and Liem R.K. Plakins: a family of versatile cytolinker proteins. Trends Cell Biol. 12 (2002) 37-45
24. Lewis A.K., and Bridgman P.C. Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity. J. Cell Biol. 119 (1992) 1219-1243
25. Limouze J., Straight A.F., Mitchison T., and Sellers J.R. Specificity of blebbistatin, an inhibitor of myosinII. J. Muscle Res. Cell Motil. 25 (2004) 337-341
26. Lin C.H., Espreafico E.M., Mooseker M.S., and Forscher P. Myosin drives retrograde f-actin flow in neuronal growth cones. Neuron 16 (1996) 769-782
27. Medeiros N.A., Burnette D.T., and Forscher P. Myosin II functions in actin-bundle turnover in neuronal growth cones. Nat. Cell Biol. 8 (2006) 215-226
28. Mitchison T., and Kirschner M. Cytoskeletal dynamics and nerve growth. Neuron 1 (1988) 761-772
29. Oberstar J.V., Challacombe J.F., Roche F.K., and Letourneau P.C. Concentration-dependent stimulation and inhibition of growth cone behavior and neurite elongation by protein kinase inhibitors KT5926 and K-252a. J. Neurobiol. 33 (1997) 161-171
30. Rösner H., and Fischer H. In growth cones of rat cerebral neurons and human neuroblastoma cells, activation of protein kinase C causes a shift from filopodial to lamellipodial actin dynamics. Neurosci. Lett. 219 (1996) 175-178
31. Ruchhoeft M.L., and Harris W.A. Myosin functions in Xenopus retinal ganglion cell growth cone motility in vivo. J. Neurobiol. 32 (1997) 567-578
32. Schäfer A.W., Kabir N., and Forscher P. Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones. J. Cell Biol. 158 (2002) 139-152
33. Schmidt J.T., Morgan P., Dowell N., and Leu B. Myosin light chain phosphorylation and growth cone motility. J. Neurobiol. 52 (2002) 175-188
34. Smith S.J. Neuronal cytomechanics: the actin-based motility of growth cones. Science 242 (1988) 708-715
35. Straight A.F., Cheung A., Limouze J., Chen I., Westwood N.J., Sellers J.R., and Mitchison T.J. Dissecting temporal and spatial control of cytokinesis with amyosin II inhibitor. Science 299 (2003) 1743-1747
36. Suter D.M., and Forscher P. Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance. J. Neurobiol. 44 (2000) 97-113
37. Wahl S., Barth H., Ciossek T., Aktories K., and Mueller B.K. Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase. J. Cell Biol. 149 (2000) 263-270
38. Waterman-Storer C.M., and Salmon E.D. Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling. J. Cell Biol. 139 (1997) 417-434
39. Wylie S.R., and Chantler P.D. Myosin IIA drives neurite retraction. Mol. Biol. Cell 14 (2003) 4654-4666
40. Yuan X.-B., Jin M., Xu X., Song Y.-Q., Wu C.-P., Poo M.-M., and Duan S. Signaling and crosstalk of Rho GTPases in mediating axon guidance. Nat. Cell Biol. 5 (2003) 1-8
41. Zhang X.F., et al. Rho-dependent contractile responses in the neuronal growth cone are independent of classical peripheral retrograde actin flow. Neuron 40 (2003) 931-944
42. Zhou F., and Cohan C.S. How actin filaments and microtubules steer growth cones to their targets. J. Neurobiol. 58 (2004) 84-91
43. Zhou F.Q., Waterman-Storer C.M., and Cohan C.S. Focal loss of actin bundles causes microtubule redistribution and growth cone turning. J. Cell Biol. 157 (2002) 839-849