A study of the lipophilicity of amide derivatives of α-(1,2,3,4- tetrahydroisoquinolin-2-yl)-γ-hydroxybutyric acid by use of RP-TLC and calculation

Journal of Planar Chromatography - Modern TLC

Volumn 20, Issue 2, 2007, Pages 101-106

  Wiȩckowski, Krzysztof ^a   Czaja, Anna ^a   Woźniak, Anna ^a   Musiał, Anna ^a   Malawska, Barbara ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Anticonvulsant activity; Derivatives of (1,2,3,4 tetrahydroisoquinolin 2 yl) hydroxybutyric acid; Lipophilicity RM0; Partition coefficient; RP TLC

Indexed keywords

ANTICONVULSANT ACTIVITIES; LIPOPHILICITY; MOBILE PHASES; PARTITION COEFFICIENTS; RETENTION DATA; REVERSED PHASE THIN LAYER CHROMATOGRAPHY (RP TLC);

AMIDES; COMPUTER SOFTWARE; FATTY ACIDS; METHANOL; THIN LAYER CHROMATOGRAPHY;

LIPIDS;

ALPHA(1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL) GAMMA HYDROXYBUTYRIC ACID; AMIDE; ANTICONVULSIVE AGENT; HYDROXYBUTYRIC ACID; METHANOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CALCULATION; CONTROLLED STUDY; DRUG STRUCTURE; ELECTRIC SHOCK; LIPOPHILICITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTITION COEFFICIENT; SEIZURE; THIN LAYER CHROMATOGRAPHY;

EID: 35048867805     PISSN: 09334173     EISSN: None     Source Type: Journal    
DOI: 10.1556/JPC.20.2007.2.6     Document Type: Article

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