Reversed-phase high performance liquid chromatographic determination of lipophilicity of potential antituberculosis compounds

Journal of Liquid Chromatography and Related Technologies

Volumn 27, Issue 16, 2004, Pages 2539-2545

  Kresta, Jan ^a   Kastner, Petr ^a   Klimeš, Jiri ^a   Klimešová, Věra ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Antituberculosis compounds; Lipophilicity; Octanol water system; RP HPLC

Indexed keywords

AROMATIC HYDROCARBONS; CORRELATION METHODS; DERIVATIVES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATHEMATICAL MODELS; SYNTHESIS (CHEMICAL);

BENZOTHIAZOLE; LIPOPHILICITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC);

DRUG PRODUCTS;

2 BENZYLSULFANYL DERIVATIVE; BENZOTHIAZOLE DERIVATIVE; METHANOL; SULFUR DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; WATER;

ARTICLE; CALCULATION; COMPUTER PROGRAM; CORRELATION ANALYSIS; DRUG DETERMINATION; DRUG STRUCTURE; LIPOPHILICITY; MATHEMATICAL ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

EID: 4644263283     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-200028388     Document Type: Article

References (22)

1. Hansch, C.; Andersen, S.M. J. Org. Chem. 1967, 32, 2583.
2. Fujita, T.; Iwasa, J.; Hansch, J. J. Am. Chem. Soc. 1964, 86, 5175.
3. Hong, H.; Wang, L.; Zou, G. J. Liq. Chromatogr. Relat. Technol. 1997, 20, 3029.
4. Yamana, S.; Tsuji, A.; Miyamoto, E.; Kubo, S. J. Pharm. Sci. 1997, 66, 747.
5. Minnick, D.J.; Brent, D.A.; Frenz, J. J. Chromatogr. 1989, 461, 177.
6. Britto, M.M.; Cass, Q.B.; Montanari, C.A.I.; Aboul-Enein, H.Y. J. Liq. Chromatogr. Relat. Technol. 1999, 22, 2139.
7. Bechalany, A.; Tsantili-Kakoulidou, A.; El Tayar, N.; Testa, B. J. Chromatogr. 1991, 541, 221.
8. Griffin, S.; Wyllie, S.G.; Markham, J. J. Chromatogr. 1999, 864, 221.
9. Klimeš, J.; Zimová, G.; Kastner, P.; Klimeš ová, V.; Palát, K. J. Liq. Chromatogr. Relat. Technol. 2001, 24, 2257.
10. Cimpan, G.; Hadaruga, M.; Miclaus, V. J. Chromatogr. A 2000, 869, 49.
11. Kastner, P.; Klimeš, J.; Velenovská, P.; Klimešová, V. J. Liq. Chromatogr. Relat. Technol. 25, 2849.
12. Cserháti, T.; Forgács, E.; Hajós, G. J. Planar Chromatogr. 1998, 11, 64.
13. Dross, K.P.; Rekker, R.F.; de Vries, G.; Mannhold, R. Quant. Struct.- Act. Relat. 1998, 17, 549.
14. Cimpan, G.; Irimie, F.; Gocan, S. J. Planar Chromatogr. 1998, 11, 342.
15. Forgács, E.; Cserháti, T.; Kaliszan, R.; Haber, P.; Nasal, A. J. Planar Chromatogr. 1998, 11, 383.
16. Kastner, P.; Kuchar, M.; Klimeš, J.; Dosedlová, D. J. Chromatogr. A 1996, 766, 165.
17. Kastner, P.; Klimeř, J.; Zimová, G.; Klimeš ová, V. J. Planar Chromatogr. 2001, 14, 291.
18. Kastner, P.; Klimeš, J.; Velenovská, P.; Klimešová, V. J. Planar Chromatogr. 2002, 15, 200.
19. Braumann, T. J. Chromatogr. 1986, 373, 191.
20. Hsie, M.M.; Dorsey, J.G. J. Chromatogr. 1993, 631, 63.
21. Jandera, P.; Kubat, J. J. Chromatogr. 1990, 500, 281.
22. Klimešová, V.; Svoboda, M.; Waisser, K.; Kaustová, J.; Buchta, V.; Král'ová, K. Eur. J. Med. Chem. 1999, 34, 433.