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Volumn 64, Issue 2, 2007, Pages 127-137
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Design, synthesis and pharmacological evaluation of α-substituted N-benzylamides of γ-hydroxybutyric acid with potential gaba-ergic activity. Part 6. Search for new anticonvulsant compounds
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Author keywords
substituted N benzylamides of hydroxybutyric acid; Anticonvulsant activity; GABA ergic activity; Molecular modeling
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Indexed keywords
3 [(4 PHENYLPIPERAZIN 1 YL)CARBONAMIDOMETHYLAMINE]TETRAHYDROFURAN 2 ONE;
4 AMINOBUTYRIC ACID;
4 AMINOBUTYRIC ACID RECEPTOR;
4 HYDROXYBUTYRIC ACID;
HARKOSERIDE;
N (2 PHENYLETHYLAMIDE) ALPHA (1,2,3,4 TETRAHYDROISOQUINOLINE) 4 BUTYRIC ACID;
N (4 FLUOROBENZYLAMIDE) ALPHA (1,2,3,4 TETRAHYDROISOQUINOLINE) 4 HYDROXYBUTYRIC ACID;
N BENZYLAMIDE ALPHA (1,2,3,4 TETRAHYDROISOQUINOLINE) 4 HYDROXYBUTYRIC ACID;
UNCLASSIFIED DRUG;
4-HYDROXYBUTYRIC ACID;
ANTICONVULSIVE AGENT;
BENZYL DERIVATIVE;
GABAERGIC RECEPTOR AFFECTING AGENT;
HYDROXYBUTYRIC ACID;
PENTETRAZOLE;
TRITIUM;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTICONVULSANT ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG BINDING;
DRUG DESIGN;
DRUG MECHANISM;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ELECTRIC SHOCK;
GABAERGIC SYSTEM;
LIGAND BINDING;
MALE;
MASS SPECTROMETRY;
MOUSE;
NEUROTOXICITY;
NONHUMAN;
RADIOASSAY;
RAT;
SEIZURE;
ANIMAL;
BRAIN CORTEX;
CHEMICAL MODEL;
CHEMICAL STRUCTURE;
CHEMICALLY INDUCED DISORDER;
CHEMISTRY;
DRUG EFFECT;
DRUG SCREENING;
INTRAPERITONEAL DRUG ADMINISTRATION;
METABOLISM;
METHODOLOGY;
SPRAGUE DAWLEY RAT;
SUBCUTANEOUS DRUG ADMINISTRATION;
SYNTHESIS;
WISTAR RAT;
ANIMALS;
ANTICONVULSANTS;
BENZYL COMPOUNDS;
CEREBRAL CORTEX;
DRUG DESIGN;
DRUG EVALUATION, PRECLINICAL;
ELECTROSHOCK;
GABA AGENTS;
HYDROXYBUTYRATES;
INJECTIONS, INTRAPERITONEAL;
INJECTIONS, SUBCUTANEOUS;
MALE;
MICE;
MODELS, CHEMICAL;
MOLECULAR STRUCTURE;
PENTYLENETETRAZOLE;
RADIOLIGAND ASSAY;
RATS;
RATS, SPRAGUE-DAWLEY;
RATS, WISTAR;
SEIZURES;
TRITIUM;
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EID: 35048836884
PISSN: 00016837
EISSN: None
Source Type: Journal
DOI: None Document Type: Article |
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Times cited : (18)
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References (21)
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