Efficient construction of a diabody using a refolding system: Anti-carcinoembryonic antigen recombinant antibody fragment

Journal of Biochemistry

Volumn 132, Issue 6, 2002, Pages 903-909

  Asano, Ryutaro ^a   Kudo, Toshio ^a   Nishimura, Yukihiro ^a   Makabe, Koki ^a   Hayashi, Hiroki ^a,b   Suzuki, Masanori ^b   Tsumoto, Kouhei ^a   Kumagai, Izumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adoptive immunotherapy; Bispecific diabody; CEA; Inclusion body

Indexed keywords

BISPECIFIC ANTIBODY; CARCINOEMBRYONIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; EPITOPE; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY CD3; RECOMBINANT ANTIBODY;

ADOPTIVE IMMUNOTHERAPY; ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; CELL INCLUSION; CELL LINE; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; PROTEIN FOLDING; PROTEIN RENATURATION; STOICHIOMETRY;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTINEOPLASTIC AGENTS; CARCINOEMBRYONIC ANTIGEN; CELL LINE, TUMOR; ESCHERICHIA COLI; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; INCLUSION BODIES; MICE; PROTEIN FOLDING; RECOMBINANT PROTEINS;

ESCHERICHIA COLI; VECTORS;

EID: 0036947103     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a003303     Document Type: Article

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