A new format of bispecific antibody: Highly efficient heterodimerization, expression and tumor cell lysis

Journal of Immunological Methods

Volumn 296, Issue 1-2, 2005, Pages 95-101

  Xie, Zhigang ^a   Guo, Ning ^a   Yu, Ming ^a   Hu, Meiru ^a   Shen, Beifen ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Bispecific antibody; Cancer; Heterodimerization; Immunotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; BISPECIFIC ANTIBODY; CD16 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; IMMUNOGLOBULIN FC FRAGMENT; TRASTUZUMAB;

ANIMAL CELL; ANTIBODY ENGINEERING; ANTIGEN BINDING; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL LINE; CHO CELL; CONTROLLED STUDY; CYTOLYSIS; DIMERIZATION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIBODIES, NEOPLASM; ANTIGENS, CD; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CHO CELLS; CRICETINAE; CRICETULUS; DIMERIZATION; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; LEUKOCYTES, MONONUCLEAR; RECEPTOR, ERBB-2; RECEPTORS, IGG; TRANSFECTION;

MAMMALIA;

EID: 12944312223     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.11.005     Document Type: Article

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