메뉴 건너뛰기




Volumn 449, Issue 7162, 2007, Pages 611-615

Snapshots of nuclear pore complexes in action captured by cryo-electron tomography

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ELECTRON; EUKARYOTE; EXPERIMENTAL STUDY; IMAGE ANALYSIS; MOLECULAR ANALYSIS; SIMULATION; TOMOGRAPHY;

EID: 34948891095     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06170     Document Type: Article
Times cited : (292)

References (30)
  • 1
    • 1842813943 scopus 로고    scopus 로고
    • The nuclear pore complex: A jack of all trades
    • Fahrenkrog, B., Koser, J. & Aebi, U. The nuclear pore complex: a jack of all trades. Trends Biochem. Sci. 29, 175-182 (2004).
    • (2004) Trends Biochem. Sci , vol.29 , pp. 175-182
    • Fahrenkrog, B.1    Koser, J.2    Aebi, U.3
  • 2
    • 0141995069 scopus 로고    scopus 로고
    • The nuclear pore complex: Nucleocytoplasmic transport and beyond
    • Fahrenkrog, B. & Aebi, U. The nuclear pore complex: nucleocytoplasmic transport and beyond. Nature Rev. Mol. Cell Biol. 4, 757-766 (2003).
    • (2003) Nature Rev. Mol. Cell Biol , vol.4 , pp. 757-766
    • Fahrenkrog, B.1    Aebi, U.2
  • 3
    • 14844330221 scopus 로고    scopus 로고
    • Structural studies by electron tomography: From cells to molecules
    • Lucic, V., Forster, F. & Baumeister, W. Structural studies by electron tomography: from cells to molecules. Annu. Rev. Biochem. 74, 833-865 (2005).
    • (2005) Annu. Rev. Biochem , vol.74 , pp. 833-865
    • Lucic, V.1    Forster, F.2    Baumeister, W.3
  • 4
    • 8844226004 scopus 로고    scopus 로고
    • Nuclear pore complex structure and dynamics revealed by cryoelectron tomography
    • Beck, M. et al. Nuclear pore complex structure and dynamics revealed by cryoelectron tomography. Science 306, 1387-1390 (2004).
    • (2004) Science , vol.306 , pp. 1387-1390
    • Beck, M.1
  • 5
    • 0029021928 scopus 로고
    • Structural plasticity of the nuclear pore complex
    • Akey, C. W. Structural plasticity of the nuclear pore complex. J. Mol. Biol. 248, 273-293 (1995).
    • (1995) J. Mol. Biol , vol.248 , pp. 273-293
    • Akey, C.W.1
  • 6
    • 0037340827 scopus 로고    scopus 로고
    • Nuclear pore complexes exceeding eightfold rotational symmetry
    • Hinshaw, J. E. & Milligan, R. A. Nuclear pore complexes exceeding eightfold rotational symmetry. J. Struct. Biol. 141, 259-268 (2003).
    • (2003) J. Struct. Biol , vol.141 , pp. 259-268
    • Hinshaw, J.E.1    Milligan, R.A.2
  • 7
    • 0019987933 scopus 로고
    • The correlation averaging of a regularly arranged bacterial cell envelope protein
    • Saxton, W. O. & Baumeister, W. The correlation averaging of a regularly arranged bacterial cell envelope protein. J. Microsc. 127, 127-138 (1982).
    • (1982) J. Microsc , vol.127 , pp. 127-138
    • Saxton, W.O.1    Baumeister, W.2
  • 8
    • 0026564158 scopus 로고
    • From lattice distortion to molecular distortion - characterizing and exploiting crystal deformation
    • Saxton, W. O., Durr, R. & Baumeister, W. From lattice distortion to molecular distortion - characterizing and exploiting crystal deformation. Ultramicroscopy 46, 287-306 (1992).
    • (1992) Ultramicroscopy , vol.46 , pp. 287-306
    • Saxton, W.O.1    Durr, R.2    Baumeister, W.3
  • 9
    • 34047159864 scopus 로고    scopus 로고
    • Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding
    • Melcak, I., Hoelz, A. & Blobel, G. Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding. Science 315, 1729-1732 (2007).
    • (2007) Science , vol.315 , pp. 1729-1732
    • Melcak, I.1    Hoelz, A.2    Blobel, G.3
  • 10
    • 9444273167 scopus 로고    scopus 로고
    • Components of coated vesicles and nuclear pore complexes share a common molecular architecture
    • Devos, D. et al. Components of coated vesicles and nuclear pore complexes share a common molecular architecture. PLoS Biol. 2, e380 (2004).
    • (2004) PLoS Biol , vol.2
    • Devos, D.1
  • 11
    • 33846956769 scopus 로고    scopus 로고
    • A general amphipathic alpha-helical motif for sensing membrane curvature
    • Drin, G. et al. A general amphipathic alpha-helical motif for sensing membrane curvature. Nature Struct. Mol. Biol. 14, 138-146 (2007).
    • (2007) Nature Struct. Mol. Biol , vol.14 , pp. 138-146
    • Drin, G.1
  • 12
    • 0037453221 scopus 로고    scopus 로고
    • Cryo-electron tomography provides novel insights into nuclear pore architecture: Implications for nucleocytoplasmic transport
    • Stoffler, D. et al. Cryo-electron tomography provides novel insights into nuclear pore architecture: implications for nucleocytoplasmic transport. J. Mol. Biol. 328, 119-130 (2003).
    • (2003) J. Mol. Biol , vol.328 , pp. 119-130
    • Stoffler, D.1
  • 13
    • 33748310680 scopus 로고    scopus 로고
    • Karyopherin-mediated import of integral inner nuclear membrane proteins
    • King, M. C., Lusk, C. P. & Blobel, G. Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442, 1003-1007 (2006).
    • (2006) Nature , vol.442 , pp. 1003-1007
    • King, M.C.1    Lusk, C.P.2    Blobel, G.3
  • 14
    • 4444284306 scopus 로고    scopus 로고
    • Imaging of single-molecule translocation through nuclear pore complexes
    • Yang, W., Gelles, J. & Musser, S. M. Imaging of single-molecule translocation through nuclear pore complexes. Proc. Natl Acad. Sci. USA 101, 12887-12892 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 12887-12892
    • Yang, W.1    Gelles, J.2    Musser, S.M.3
  • 15
    • 0031562696 scopus 로고    scopus 로고
    • Three-dimensional visualization of the route of protein import: The role of nuclear pore complex substructures
    • Rutherford, S. A., Goldberg, M. W. & Allen, T. D. Three-dimensional visualization of the route of protein import: the role of nuclear pore complex substructures. Exp. Cell Res. 232, 146-160 (1997).
    • (1997) Exp. Cell Res , vol.232 , pp. 146-160
    • Rutherford, S.A.1    Goldberg, M.W.2    Allen, T.D.3
  • 16
    • 0031907210 scopus 로고    scopus 로고
    • Active nuclear pore complexes in Chironomus: Visualization of transporter configurations related to mRNP export
    • Kiseleva, E., Goldberg, M. W., Allen, T. D. & Akey, C. W. Active nuclear pore complexes in Chironomus: visualization of transporter configurations related to mRNP export. J. Cell Sci. 111, 223-236 (1998).
    • (1998) J. Cell Sci , vol.111 , pp. 223-236
    • Kiseleva, E.1    Goldberg, M.W.2    Allen, T.D.3    Akey, C.W.4
  • 17
    • 0029797940 scopus 로고    scopus 로고
    • Sequential binding of import ligands to distinct nucleopore regions during their nuclear import
    • Pante, N. & Aebi, U. Sequential binding of import ligands to distinct nucleopore regions during their nuclear import. Science 273, 1729-1732 (1996).
    • (1996) Science , vol.273 , pp. 1729-1732
    • Pante, N.1    Aebi, U.2
  • 18
    • 0037043339 scopus 로고    scopus 로고
    • The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import
    • Walther, T. C. et al. The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import. J. Cell Biol. 158, 63-77 (2002).
    • (2002) J. Cell Biol , vol.158 , pp. 63-77
    • Walther, T.C.1
  • 20
    • 0035931750 scopus 로고    scopus 로고
    • Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import
    • Ben-Efraim, I. & Gerace, L. Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import. J. Cell Biol. 152, 411-417 (2001).
    • (2001) J. Cell Biol , vol.152 , pp. 411-417
    • Ben-Efraim, I.1    Gerace, L.2
  • 21
    • 0030455748 scopus 로고    scopus 로고
    • A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex
    • Matunis, M. J., Coutavas, E. & Blobel, G. A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J. Cell Biol. 135, 1457-1470 (1996).
    • (1996) J. Cell Biol , vol.135 , pp. 1457-1470
    • Matunis, M.J.1    Coutavas, E.2    Blobel, G.3
  • 22
    • 0029070074 scopus 로고
    • Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region
    • Wu, J., Matunis, M. J., Kraemer, D., Blobel, G. & Coutavas, E. Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. J. Biol. Chem. 270, 14209-14213 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 14209-14213
    • Wu, J.1    Matunis, M.J.2    Kraemer, D.3    Blobel, G.4    Coutavas, E.5
  • 23
    • 22244450050 scopus 로고    scopus 로고
    • Evidence for ectopic neurotransmission at a neuronal synapse
    • Coggan, J. S. et al. Evidence for ectopic neurotransmission at a neuronal synapse. Science 309, 446-451 (2005).
    • (2005) Science , vol.309 , pp. 446-451
    • Coggan, J.S.1
  • 24
    • 12344323514 scopus 로고    scopus 로고
    • Quantitative models of nuclear transport
    • Becskei, A. & Mattaj, I. W. Quantitative models of nuclear transport. Curr. Opin. Cell Biol. 17, 27-34 (2005).
    • (2005) Curr. Opin. Cell Biol , vol.17 , pp. 27-34
    • Becskei, A.1    Mattaj, I.W.2
  • 26
    • 0037416225 scopus 로고    scopus 로고
    • Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation
    • Gorlich, D., Seewald, M. J. & Ribbeck, K. Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. EMBO J. 22, 1088-1100 (2003).
    • (2003) EMBO J , vol.22 , pp. 1088-1100
    • Gorlich, D.1    Seewald, M.J.2    Ribbeck, K.3
  • 27
    • 16844374515 scopus 로고    scopus 로고
    • A systems analysis of importin-α-β mediated nuclear protein import
    • Riddick, G. & Macara, I. G. A systems analysis of importin-α-β mediated nuclear protein import. J. Cell Biol. 168, 1027-1038 (2005).
    • (2005) J. Cell Biol , vol.168 , pp. 1027-1038
    • Riddick, G.1    Macara, I.G.2
  • 28
    • 27744577638 scopus 로고    scopus 로고
    • Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling
    • Matsuura, Y. & Stewart, M. Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling. EMBO J. 24, 3681-3689 (2005).
    • (2005) EMBO J , vol.24 , pp. 3681-3689
    • Matsuura, Y.1    Stewart, M.2
  • 29
    • 33750701489 scopus 로고    scopus 로고
    • FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties
    • Frey, S., Richter, R. P. & Gorlich, D. FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science 314, 815-817 (2006).
    • (2006) Science , vol.314 , pp. 815-817
    • Frey, S.1    Richter, R.P.2    Gorlich, D.3
  • 30
    • 33947727395 scopus 로고    scopus 로고
    • Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex
    • Patel, S. S., Belmont, B. J., Sante, J. M. & Rexach, M. F. Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129, 83-96 (2007).
    • (2007) Cell , vol.129 , pp. 83-96
    • Patel, S.S.1    Belmont, B.J.2    Sante, J.M.3    Rexach, M.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.