From circadian rhythms to clock genes in depression

International Clinical Psychopharmacology

Volumn 22, Issue SUPPL. 2, 2007, Pages

  Turek, Fred W ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Circadian; Clock genes; Depression; Sleep wake cycle

Indexed keywords

CORTICOTROPIN; CRYPTOCHROME; CRYPTOCHROME 1; CRYPTOCHROME 2; GROWTH HORMONE; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; PER1 PROTEIN; PER2 PROTEIN; PROLACTIN; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG;

BEHAVIOR DISORDER; BRAIN VENTRICLE; CASEIN KINASE EPISOLON GENE; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SLEEP DISORDER; CLOCK GENE; CRY1 GENE; CRY2 GENE; DEPRESSION; DISEASE EXACERBATION; DISEASE SEVERITY; DOUBLETIME GENE; DROSOPHILA; FEEDING; GENE; GENE FUNCTION; GENE MUTATION; GENETIC TRANSCRIPTION; HORMONE RELEASE; HUMAN; HYPOTHALAMUS; INSOMNIA; LOCOMOTION; MALAISE; MEDICAL LITERATURE; MOLECULAR CLOCK; MOUSE STRAIN; MUTAGENESIS; NEUROBIOLOGY; NONHUMAN; OPTIC CHIASM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REM SLEEP; REVIEW; SIGNAL TRANSDUCTION; SLEEP WAKING CYCLE; SUPRACHIASMATIC NUCLEUS;

ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; DEPRESSION; DEPRESSIVE DISORDER; HUMANS; SLEEP DISORDERS, CIRCADIAN RHYTHM;

EID: 34948847559     PISSN: 02681315     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.yic.0000277956.93777.6a     Document Type: Review

References (67)

1. Abe M, Herzog ED, Yamazaki S, Straume M, Tei H, Sakaki Y, et al. (2002). Circadian rhythms in isolated brain regions. J Neurosci 22:350-356.
2. Albrecht U, Sun ZS, Eichele G, Lee CC (1997). A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell 91:1055-1064.
3. Alvarez B, Dahliz M, Vignau J, Parkes J (1992). The delayed sleep phase syndrome: clinical and investigative findings in 14 subjects. J Neurol Neurosurg Psychiat 55:665-670.
4. Ancoli-Israel S, Schnierow B, Kelsoe J, Fink R (2001). A pedigree of one family with delayed sleep phase syndrome. Chronobiol Int 18:831-840.
5. Antoch MP, Song E, Chang A, Vitaterna MH, Zhao Y, Wilsbacher LD, et al. (1997). Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell 89:655-667.
6. Archer SN, Robilliard DL, Skene DJ, Smits M, Williams A, Arendt J, et al. (2003). A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep 26:413-415.
7. Asher G, Schibler U (2006). A CLOCK-less clock. Trends Cell Biol 16:547-549.
8. Audinot V, Mailliet F, Lahaye-Brasseur C, Bonnaud A, Le Gall A, Amosse C, et al. (2003). New selective ligands of human cloned melatonin MT1 and MT2 receptors. Naunyn Schmiedebergs Arch Pharmacol 367:553-561.
9. Benca RM (2005). Mood disorders. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. Philadelphia: Saunders; pp. 1311-1326.
10. Czeisler C, Cajochen C, Turek FW (2000). Section four-melatonin in the regulation of sleep and circadian rhythms. In: Kryger MH, Roth T, Dement WC, editors. Principles and practices of sleep medicine. New York: WB Saunders; pp. 400-406.
11. Debruyne JP, Noton E, Lambert CM, Maywood ES, Weaver DR, Reppert SM (2006). A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron 50:465-477.
12. Dijk D-J, Cajochen C (1997). Melatonin and the circadian regulation of sleep initiation, consolidation, structure and the sleep EEG. J Biol Rhythms 12:627-635.
13. Dubocovich ML, Yun K, Al-Ghoul WM, Benloucif S, Masana MI (1998). Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. Faseb J 12:1211-1220.
14. Hattar S, Liao HW, Takao M, Berson DM, Yau KW (2002). Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science 295:1065-1070.
15. Hendricks JC (2003). Invited review: sleeping flies don't lie: the use of Drosophila melanogaster to study sleep and circadian rhythms. J Appl Physiol 94:1660-1672. Discussion: 1673.
16. Hohjoh H, Takasu M, Shishikura K, Takahashi Y, Honda Y, Tokunaga K (2003). Significant association of the arylalkylamine N-acetyltransferase (AA-NAT) gene with delayed sleep phase syndrome. Neurogenetics 4:151-153.
17. Inouye SIT, Takahashi JS, Wollnik F, Turek FW (1988). Inhibitor of protein synthesis phase shifts a circadian pacemaker in the mammalian SCN. Am J Physiol 255: R1055-R1058.
18. Iwase T, Kajimura N, Uchiyama M, Ebisawa T, Yoshimura K, Kamei Y, et al. (2002). Mutation screening of the human Clock gene in circadian rhythm sleep disorders. Psychiatry Res 109:121-128.
19. Jackson A, Cavanagh J, Scott J (2003). A systematic review of manic and depressive prodromes. J Affect Disord 74:209-217.
20. Jones CR, Campbell SS, Zone SE, Cooper F, De Sano A, Murphy PJ, et al. (1999). Familial advanced sleep-phase syndrome: a short-period circadian rhythm variant in humans. Nat Med 5:1062-1065.
21. Katzenberg D, Young T, Finn L, Lin L, King DP, Takahashi JS, et al. (1998). A CLOCK polymorphism associated with human diurnal preference. Sleep 21:569-576.
22. King DP, Zhao Y, Sangoram AM, Wilsbacher LD, Tanaka M, Antoch MP, et al. (1997). Positional cloning of the mouse circadian Clock gene. Cell 89:641-653.
23. Kohsaka A, Bass J (2007). A sense of time: how molecular clocks organize metabolism. Trends Endocrinol Metab 18:4-11.
24. Kolker DE, Fukuyama H, Huang DS, Takahashi JS, Horton TH, Turek FW (2003). Aging alters circadian and light-induced expression of clock genes in golden hamsters. J Biol Rhythms. 18:159-169.
25. Konopka RJ, Benzer S (1971). Clock mutants of Drosophila melanogaster. Proc Natl Acad Sci U S A 68:2112-2116.
26. Kupfer DJ (1999). Pathophysiology and management of insomnia during depression. Ann Clin Psychiatry 11:267-276.
27. Laposky AD, Shelton J, Bass J, Dugovic C, Perrino N, Turek FW (2006). Altered sleep regulation in leptin deficient mice. Am J Physiol Regul Integr Comp Physiol 4:894-903.
28. Lewy AJ, Sack RL (1997). Exogenous melatonin's phase-shifting effects on the endogenous melatonin profile in sighted humans: a brief review and critique of the literature. J Biol Rhythms 12:588-594.
29. Linkowski P, Mendlewicz J, Leclercq R, Van Cauter E (1985). The 24-hour profile of adrenocorticotropin and cortisol in major depressive illness. J Clin Endocrinol Metab 61:429-438.
30. Lowrey PL, Takahashi JS (2000). Genetics of the mammalian circadian system: photic entrainment, circadian pacemaker mechanisms and posttranslational regulation. Annu Rev Genet 34:533-562.
31. Marano HE (2005). Bedfellows: insomnia and depression. In: Psychology today magazine.
32. Mendlewicz J, Linkowski P, Kerkhofs M, Desmedt D, Golstein J, Copinschi G, et al. (1985). Diurnal hypersecretion of growth hormone in depression. J Clin Endocrinol Metab 60:505-512.
33. Naylor E, Bergmann BM, Krauski K, Zee PC, Takahashi JS, Vitaterna MH, et al. (2000). The circadian Clock mutation alters sleep homeostatsis in the mouse. J Neurosci 20:8138-8143.
34. Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, et al. (2002). Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109:307-320.
35. Perlis ML, Giles DE, Buysse DJ, Tu X, Kupfer DJ (1997). Self-reported sleep disturbance as a prodromal symptom in recurrent depression. J Affect Disord 42:209-212.
36. Redman J, Armstrong S, Ng KT (1983). Free-running activity rhythms in the rat: entrainment by melatonin. Science 219:1089-1091.
37. Reid KJ, Chang AM, Dubocovich ML, Turek FW, Takahashi JS, Zee PC (2001). Familial advanced sleep phase syndrome. Arch Neurol 7:1089-1094.
38. Rivara S, Mor M, Silva C, Zuliani V, Vacondio F, Spadoni G, et al. (2003). Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation. J Med Chem 46:1429-1439.
39. Robilliard DL, Archer SN, Arendt J, Lockley SW, Hack LM, English J, et al. (2002). The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects. J Sleep Res 11:305-312.
40. Rogers NL, Dinges D, Allison KC, Maislin G, Martino N, O'Reardon JP, et al. (2006). Assessment of sleep in women with night eating syndrome. Sleep (in press).
41. Satoh K, Mishima K, Inoue Y, Ebisawa T, Shimizu T (2003). Two pedigrees of familial advanced sleep phase syndrome in Japan. Sleep 26:416-417.
42. Sehgal A, Price JL, Man B, Young MW (1994). Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless. Science 263:1603-1606.
43. Shearman LP, Zylka MJ, Weaver DR, Kolakowski LFJ, Reppert SM (1997). Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron 19:1261-1269.
44. Sugden D, Yeh LK, Teh MT (1999). Design of subtype selective melatonin receptor agonists and antagonists. Reprod Nutr Dev 39:335-344.
45. Takahashi Y, Hohjoh H, Matsuura K (2000). Predisposing factors in delayed sleep phase syndrome. Psychiatry Clin Neurosci 54:356-358.
46. Taylor DJ, Lichstein KL, Durrence HH, Reidel BW, Bush AJ (2005). Epidemiology of insomnia, depression, and anxiety. Sleep 28:1457-1464.
47. Tei H, Okamura H, Shigeyoshi Y, Fukuhara C, Ozawa R, Hirose M, et al. (1997). Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature 389:512-516.
48. Thase ME (1999). Antidepressant treatment of the depressed patient with insomnia. J Clin Psychiatry 60 (Suppl 17):28-31. Discussion:46-48.
49. Toh KL, Jones CR, He Y, Eide EJ, Hinz WA, Virshup DM, et al. (2001). An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 291:1040-1043.
50. Turek FW (1987). Pharmacological probes of the mammalian circadian clock: use of the phase response curve approach. Trends Pharmacol Sci 8:212-217.
51. Turek FW (2005). Insomnia and depression: if it looks and walks like a duck. Sleep 28:1362-1363.
52. Turek FW (2006). Staying awake for dinner - staying asleep until breakfast. Sleep 29:747-748.
53. Turek FW, Vitaterna MH (2007). Circadian rhythms, genetics of. In: Fink G, editor. Encyclopedia of stress. 2nd ed. Vol. 1. San Diego, CA: Elsevier; pp. 508-512.
54. Turek FW, Pénev P, Zhang Y, Van Reeth O, Takahashi JS, Zee PC (1994). Circadian clocks and their adjustment, Ciba foundation symposium. London: Pitman Press; pp. 212-234.
55. Turek FW, Zee P, Van Reeth O (1999). Melatonin and aging. Adv Exp Med Biol 460:435-440.
56. Turek FW, Scarbrough K, Penev P, Labyak S, Valentinuzzi VS, Van Reeth O (2001). Aging of the Mammalian Circadian System. In: Takahashi JS, Turek FW, Moore RY, editors. Circadian Clocks. Vol. 12. New York: Kluwer Academic/Plenum Publishers; pp. 292-317.
57. Turek FW, Dugovic C, Laposky A (2005a). Master Circadian Clock, Master Circadian Rhythm. In: Kryger MH, Roth T, Dement W, editors. Principles and practice of sleep medicine. 4th ed. New York: WB Saunders; pp. 318-320.
58. Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDearmon E, et al. (2005b). Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308:1043-1045.
59. Van Cauter E, Turek FW (1986). Depression: a disorder of timekeeping? Perspect Biol Med 29:510-519.
60. Van Cauter E, Turek FW (2000). Roles of sleep-wake and dark-light cycles in the control of endocrine, metabolic, cardiovascular and cognitive function. In: McEwen BS, ed. Handbook of physiology, section 7: the endocrine system. New York: Oxford University Press; pp. 313-330.
61. Van Cauter E, Copinschi G, Turek FW (2001). Endocrine and other biologic rhythms. In: DeGroot LJ, Jameson JL, editors. Endocrinology. 4th ed. Vol. 1. New York: WB Saunders; pp. 235-256.
62. Van Reeth O, Olivares W, Zhang Y, Zee PC, Mocaer E, Defrance R, et al. (1997). Comparative effects of a melatonin-agonist on the circadian system in mice and Syrian hamsters. Brain Res 762:185-194.
63. Van Reeth O, Olivares E, Turek FW, Granjon L, Mocaer E (1998). Resynchronisation of a diurnal rodent circadian clock accelerated by a melatonin agonist. Neuroreport 9:1901-1905.
64. Vitaterna MH, King DP, Chang A-M, Kornhauser JM, Lowrey PL, McDonald JD, et al. (1994). Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264:719-725.
65. Wallez V, Durieux-Poissonnier S, Chavatte P, Boutin JA, Audinot V, Nicolas JP, et al. (2002). Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands. J Med Chem 45:2788-2800.
66. Wehr TA, Goodwin FK (1983). Circadian rhythms in psychiatry. Pacific Grove, California: Boxwood.
67. Yous S, Durieux-Poissonnier S, Lipka-Belloli E, Guelzim H, Bochu C, Audinot V, et al. (2003). Design and synthesis of 3-phenyl tetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands. Bioorg Med Chem 11:753-759.