Significant association of the arylalkylamine N-acetyltransferase (AA-NAT) gene with delayed sleep phase syndrome

Neurogenetics

Volumn 4, Issue 3, 2003, Pages 151-153

  Hohjoh, Hirohiko ^a,c   Takasu, Miwa ^a   Shishikura, Kaori ^a   Takahashi, Yasurou ^b   Honda, Yutaka ^b   Tokunaga, Katsushi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SEIWA HOSPITAL   (Japan)

^c NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Arylalkylamine N acetyltransferase; Delayed sleep phase syndrome; Single nucleotide polymorphism

Indexed keywords

ACYLTRANSFERASE; ALANINE; AMINE N ACETYLTRANSFERASE; AMINO ACID; NUCLEOTIDE; THREONINE; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DELAYED SLEEP PHASE SYNDROME; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HEALTH STATUS; HUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP DISORDER;

EID: 0037611063     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10048-002-0141-9     Document Type: Article

References (8)

1. Dollins AB, Zhdanova IV, Wurtman RJ, Lynch HJ, Deng MH (1994) Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc Natl Acad Sci U S A 91:1824-1828
2. Arendt J (1995) Melatonin and the mammalian pineal gland. Chapman and Hall, London, pp 201-285
3. Klein DC, Coon SL, Roseboom PH, Weller JL, Bernard M, Gastel JA, Zatz M, Iuvone PM, Rodriguez IR, Begay V, Falcon J, Cahill GM, Cassone VM, Baler R (1997) The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland. Recent Prog Horm Res 52:307-358
4. Foulker NS, Borjigin J, Snyder SH, Sassone-Corsi P (1997) Rhythmic transcription: the molecular basis of circadian melatonin synthesis. Trends Neurosci 20:487-492
5. Coon SL, Mazuruk K, Bernard M, Roseboom PH, Klein DC, Rodriguez IR (1996) The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression. Genomics 34:76-84
6. Diagnostic Classification Steering Committee (1990) Delayed sleep phase syndrome. In: International classification of sleep disorders: diagnostic and coding manual. American Sleep Disorder Association, Rochester, Minn. USA, pp 128-133
7. Shibui K, Uchiyama M, Okawa M (1999) Melatonin rhythms in delayed sleep phase syndrome. J Biol Rhythms 14:72-76
8. Hohjoh H, Nakayama T, Ohashi J, Miyagawa T, Tanaka H, Akaza T, Honda Y, Juji T, Tokunaga K (1999) Significant association of a single nucleotide polymorphism in the tumor necrosis factor-alpha (TNF-α) gene promoter with human narcolepsy. Tissue Antigens 54:138-145