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Volumn 204, Issue 10, 2007, Pages 2249-2252

If the treatment works, do we need to know why?: The promise of immunotherapy for experimental medicine

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CORTICOSTEROID; ETANERCEPT; INFLIXIMAB; METHOTREXATE; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR;

EID: 34948836136     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20071737     Document Type: Review
Times cited : (12)

References (32)
  • 1
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids - new mechanisms for old drugs
    • Rhen, T., and J.A. Cidlowski. 2005. Antiinflammatory action of glucocorticoids - new mechanisms for old drugs. N. Engl. J. Med. 353:1711-1723.
    • (2005) N. Engl. J. Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 2
    • 14844311937 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease
    • Brown, S.J., and M.T. Abreu. 2005. Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease. Curr. Opin. Drug Discov. Devel. 8:160-168.
    • (2005) Curr. Opin. Drug Discov. Devel , vol.8 , pp. 160-168
    • Brown, S.J.1    Abreu, M.T.2
  • 6
    • 0345490890 scopus 로고    scopus 로고
    • Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa: Data from the STURE registry showing that switching tumour necrosis factor alpha blockers can make sense
    • van Vollenhoven, R., A. Harju, S. Brannemark, and L. Klareskog. 2003. Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa: data from the STURE registry showing that switching tumour necrosis factor alpha blockers can make sense. Ann. Rheum. Dis. 62:1195-1198.
    • (2003) Ann. Rheum. Dis , vol.62 , pp. 1195-1198
    • van Vollenhoven, R.1    Harju, A.2    Brannemark, S.3    Klareskog, L.4
  • 7
    • 33846239331 scopus 로고    scopus 로고
    • Outcomes after switching from one anti-tumor necrosis factor alpha agent to a second anti-tumor necrosis factor alpha agent in patients with rheumatoid arthritis: Results from a large UK national cohort study
    • Hyrich, K.L., M. Lunt, K.D. Watson, D.P. Symmons, and A.J. Silman. 2006. Outcomes after switching from one anti-tumor necrosis factor alpha agent to a second anti-tumor necrosis factor alpha agent in patients with rheumatoid arthritis: results from a large UK national cohort study. Arthritis Rheum. 56:13-20.
    • (2006) Arthritis Rheum , vol.56 , pp. 13-20
    • Hyrich, K.L.1    Lunt, M.2    Watson, K.D.3    Symmons, D.P.4    Silman, A.J.5
  • 8
    • 33846446041 scopus 로고    scopus 로고
    • Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β
    • Nadkarni, S., C. Mauri, and M.R. Ehrenstein. 2007. Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β. J. Exp. Med. 204:33-39.
    • (2007) J. Exp. Med , vol.204 , pp. 33-39
    • Nadkarni, S.1    Mauri, C.2    Ehrenstein, M.R.3
  • 9
    • 0031899715 scopus 로고    scopus 로고
    • B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)
    • Svensson, L., J. Jirholt, R. Holmdahl, and L. Jansson. 1998. B cell-deficient mice do not develop type II collagen-induced arthritis (CIA). Clin. Exp. Immunol. 111:521-526.
    • (1998) Clin. Exp. Immunol , vol.111 , pp. 521-526
    • Svensson, L.1    Jirholt, J.2    Holmdahl, R.3    Jansson, L.4
  • 10
    • 0026644298 scopus 로고
    • Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams, R.O., M. Feldmann, and R.N. Maini. 1992. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. USA. 89:9784-9788.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9784-9788
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 11
    • 0030267786 scopus 로고    scopus 로고
    • Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice
    • Mori, L., S. Iselin, G. De Libero, and W. Lesslauer. 1996. Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice. J. Immunol. 157:3178-3182.
    • (1996) J. Immunol , vol.157 , pp. 3178-3182
    • Mori, L.1    Iselin, S.2    De Libero, G.3    Lesslauer, W.4
  • 12
    • 0034967902 scopus 로고    scopus 로고
    • Severe inflammatory arthritis and lymphadenopathy in the absence of TNF
    • Campbell, I.K., K. O'Donnell, K.E. Lawlor, and I.P. Wicks. 2001. Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. J. Clin. Invest. 107:1519-1527.
    • (2001) J. Clin. Invest , vol.107 , pp. 1519-1527
    • Campbell, I.K.1    O'Donnell, K.2    Lawlor, K.E.3    Wicks, I.P.4
  • 13
    • 0142041982 scopus 로고    scopus 로고
    • Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
    • Feldmann, M., and R.N. Maini. 2003. Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. Nat. Med. 9:1245-1250.
    • (2003) Nat. Med , vol.9 , pp. 1245-1250
    • Feldmann, M.1    Maini, R.N.2
  • 15
    • 34548715943 scopus 로고    scopus 로고
    • B cell depletion delays collagen-induced arthritis in mice: Arthritis induction requires synergy between humoral and cell-mediated immunity
    • Yanaba, K., Y. Hamaguchi, G.M. Venturi, D.A. Steeber, E.W. St Clair, and T.F. Tedder. 2007. B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity. J. Immunol. 179:1369-1380.
    • (2007) J. Immunol , vol.179 , pp. 1369-1380
    • Yanaba, K.1    Hamaguchi, Y.2    Venturi, G.M.3    Steeber, D.A.4    St Clair, E.W.5    Tedder, T.F.6
  • 16
    • 0025000863 scopus 로고
    • An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis
    • Ruddle, N.H., C.M. Bergman, K.M. McGrath, E.G. Lingenheld, M.L. Grunnet, S.J. Padula, and R.B. Clark. 1990. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J. Exp. Med. 172:1193-1200.
    • (1990) J. Exp. Med , vol.172 , pp. 1193-1200
    • Ruddle, N.H.1    Bergman, C.M.2    McGrath, K.M.3    Lingenheld, E.G.4    Grunnet, M.L.5    Padula, S.J.6    Clark, R.B.7
  • 17
    • 0026094706 scopus 로고
    • Anti-tumor necrosis factor therapy abrogates autoimmune demyelination
    • Selmaj, K., C.S. Raine, and A.H. Cross. 1991. Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann. Neurol. 30:694-700.
    • (1991) Ann. Neurol , vol.30 , pp. 694-700
    • Selmaj, K.1    Raine, C.S.2    Cross, A.H.3
  • 18
    • 0038917435 scopus 로고    scopus 로고
    • Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting
    • Korner, H., D.S. Riminton, D.H. Strickland, F.A. Lemckert, J.D. Pollard, and J.D. Sedgwick. 1997. Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J. Exp. Med. 186:1585-1590.
    • (1997) J. Exp. Med , vol.186 , pp. 1585-1590
    • Korner, H.1    Riminton, D.S.2    Strickland, D.H.3    Lemckert, F.A.4    Pollard, J.D.5    Sedgwick, J.D.6
  • 19
    • 0035128996 scopus 로고    scopus 로고
    • Genetic models for CNS inflammation
    • Owens, T., H. Wekerle, and J. Antel. 2001. Genetic models for CNS inflammation. Nat. Med. 7:161-166.
    • (2001) Nat. Med , vol.7 , pp. 161-166
    • Owens, T.1    Wekerle, H.2    Antel, J.3
  • 20
    • 0033546665 scopus 로고    scopus 로고
    • TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
    • 1999. TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Neurology. 53:457-465.
    • (1999) Neurology , vol.53 , pp. 457-465
  • 21
    • 0030456897 scopus 로고    scopus 로고
    • Experimental auto-immune encephalomyelitis induction in genetically B cell-deficient mice
    • Wolf, S.D., B.N. Dittel, F. Hardardottir, and C.A. Janeway Jr. 1996. Experimental auto-immune encephalomyelitis induction in genetically B cell-deficient mice. J. Exp. Med. 184:2271-2278.
    • (1996) J. Exp. Med , vol.184 , pp. 2271-2278
    • Wolf, S.D.1    Dittel, B.N.2    Hardardottir, F.3    Janeway Jr., C.A.4
  • 23
    • 0032729174 scopus 로고    scopus 로고
    • B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide
    • Lyons, J.A., M. San, M.P. Happ, and A.H. Cross. 1999. B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide. Eur. J. Immunol. 29:3432-3439.
    • (1999) Eur. J. Immunol , vol.29 , pp. 3432-3439
    • Lyons, J.A.1    San, M.2    Happ, M.P.3    Cross, A.H.4
  • 24
    • 33750627447 scopus 로고    scopus 로고
    • Roles of immunoglobulins and B cells in multiple sclerosis: From pathogenesis to treatment
    • Antel, J., and A. Bar-Or. 2006. Roles of immunoglobulins and B cells in multiple sclerosis: from pathogenesis to treatment. J. Neuroimmunol. 180:3-8.
    • (2006) J. Neuroimmunol , vol.180 , pp. 3-8
    • Antel, J.1    Bar-Or, A.2
  • 25
    • 33750485302 scopus 로고    scopus 로고
    • Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor
    • Winthrop, K.L. 2006. Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor. Nat. Clin. Pract. Rheumatol. 2:602-610.
    • (2006) Nat. Clin. Pract. Rheumatol , vol.2 , pp. 602-610
    • Winthrop, K.L.1
  • 27
    • 34047142747 scopus 로고    scopus 로고
    • Repeated B lymphocyte depletion with rituximab in rheumatoid arthritis over 7 yrs
    • Popa, C., M.J. Leandro, G. Cambridge, and J.C. Edwards. 2007. Repeated B lymphocyte depletion with rituximab in rheumatoid arthritis over 7 yrs. Rheumatology (Oxford). 46:626-630.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 626-630
    • Popa, C.1    Leandro, M.J.2    Cambridge, G.3    Edwards, J.C.4
  • 28
    • 0037085795 scopus 로고    scopus 로고
    • Long-lasting memory-resting and memory-eff ector CD4+ T cells in human X-linked agammaglobulinemia
    • Paroli, M., D. Accapezzato, V. Francavilla, A. Insalaco, A. Plebani, F. Balsano, and V. Barnaba. 2002. Long-lasting memory-resting and memory-eff ector CD4+ T cells in human X-linked agammaglobulinemia. Blood. 99:2131-2137.
    • (2002) Blood , vol.99 , pp. 2131-2137
    • Paroli, M.1    Accapezzato, D.2    Francavilla, V.3    Insalaco, A.4    Plebani, A.5    Balsano, F.6    Barnaba, V.7
  • 30
    • 34249739160 scopus 로고    scopus 로고
    • Cytokines and interventional immunology
    • Hafler, D. 2007. Cytokines and interventional immunology. Nat. Rev. Immunol. 7:423.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 423
    • Hafler, D.1
  • 31
    • 27144483896 scopus 로고    scopus 로고
    • CD3-specific antibodies restore self-tolerance: Mechanisms and clinical applications
    • Chatenoud, L. 2005. CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications. Curr. Opin. Immunol. 17:632-637.
    • (2005) Curr. Opin. Immunol , vol.17 , pp. 632-637
    • Chatenoud, L.1


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